Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
01/2005
01/06/2005US20050002933 Proliferation and/or differentiation of stem and progenitor cells from embryo or adult
01/06/2005US20050002920 Collecting, activating, culturing and optionally expanding peripheral blood mononuclear cells then hypomethylating with 5-aza-cytidine or 5-aza-2'-deoxycytidine
01/06/2005US20050002919 Using modified cells for drug, diagnostic agent and/or toxin delivery to target tissues; novel genetically altered human progenitor cells
01/06/2005US20050002917 Regulation of Acheron expression
01/06/2005US20050002915 Enhancement of angiogenesis to grafts using cells engineered to produce growth factors
01/06/2005US20050002913 Hematopoietic stem cell gene therapy
01/06/2005US20050002908 Method for producing a recombinant adeno-associated virus, suitable means therefor and use for producing a medicament
01/06/2005US20050002907 Mutated woodchuck posttranscriptional regulatory element (WPRE) sequence having ablated X protein tumorigenic activity; safely used in retroviral and lentiviral vectors to enhance expression levels of heterologous genes or nucleotides
01/06/2005US20050002906 Preferentially amplifying in tumors following cancer cell activation of specific gene regulatory region
01/06/2005US20050002905 RAAV vector-based pro-opiomelanocortin compositions and methods of use
01/06/2005US20050002903 Gene delivery system and methods of use
01/06/2005CA2530248A1 Modified vectors for organelle transfection
01/06/2005CA2530020A1 Novel .beta.-actin and rps21 promoters and uses thereof
01/06/2005CA2529943A1 Peptides derived from the protein mmp-2, and the use thereof in antitumoral immunotherapy
01/06/2005CA2529145A1 Nucleic acid sequences encoding and compositions comprising ige signal peptide and/or il-15 and methods for using the same
01/06/2005CA2529103A1 Use of a recombinant vector encoding il-10 for treating neuropathic pain
01/06/2005CA2528597A1 Stabilized immunomodulatory oligonucleotides
01/06/2005CA2528511A1 Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses
01/06/2005CA2527958A1 Methods and compositions for enhancing the efficacy and specificity of rnai
01/06/2005CA2527957A1 Use of genes differentially expressed during aging of liver for treatment and diagnosis
01/06/2005CA2526639A1 Chimeric rnas and their use for cancer diagonostics and therapy
01/05/2005EP1493033A2 Sc6 for diagnosis of hypoxia related conditions
01/05/2005EP1492890A2 Large scale methods of producing adenovirus and adenovirus seed stocks
01/05/2005EP1492885A2 Schizophrenia associated genes
01/05/2005EP1492883A2 Diagnostics and therapeutics for diseases associated with neuropeptide ff receptor 2 (npff2)
01/05/2005EP1492876A1 Cationic amphiphiles for intracellular delivery of therapeutic molecules, composition, process and use thereof
01/05/2005EP1492875A1 Adeno-associated virus producer system
01/05/2005EP1492817A2 Therapeutic monoclonal anti-tirc7 antibodies for use in immune related and other diseases
01/05/2005EP1492815A2 Cells transfected with a nucleotide sequence encoding glp-1 and secreting insulin in a glucose-dependent manner
01/05/2005EP1492812A2 Modulator of the notch signalling pathway and use thereof in medical treatment
01/05/2005EP1492570A2 Method of diagnosis and treatment of breast lesions
01/05/2005EP1492563A2 Compositions and methods for the diagnosis and treatment of herpes simplex virus infection
01/05/2005EP1492557A2 Xcrf polynucleotides and polypeptides and uses thereof
01/05/2005EP1492555A2 Compositions and methods for modulation of effects on phagocyte and lymphoid cell population
01/05/2005EP1492554A2 Spherical protein particles and methods of making and using them
01/05/2005EP1492552A2 Diagnostics and therapeutics for diseases associated with n-formyl peptide receptor like 1 (fprl1)
01/05/2005EP1492516A2 Use of mob-5 in pain
01/05/2005EP1420643A4 Enhancement of transfection of dna into the liver
01/05/2005EP1200580B1 MODULATION OF OLIGONUCLEOTIDE CpG-MEDIATED IMMUNE STIMULATION BY POSITIONAL MODIFICATION OF NUCLEOSIDES
01/05/2005EP1015014A4 Methods and compositions for inhibiting angiogenesis
01/05/2005DE19957065B4 Screening-Verfahren für Arzneistoffe A screening method for drugs
01/05/2005CN1561396A Method for regulating the expression of genes carried on a viral vector
01/05/2005CN1561344A Angiogenesis-inhibitory tripeptides, compositions and their methods of use
01/05/2005CN1561343A Soluble T cell receptor
01/05/2005CN1561229A Virus coat protein/receptor chimeras and methods of use
01/05/2005CN1561228A Enhancing organ maturity in neonates and predicting their duration of intensive care
01/05/2005CN1561223A New drug
01/05/2005CN1561199A Pharmaceutical composition comprising lipids comprising a polar and a nonpolar moiety
01/05/2005CN1560259A DNA vaccine carrier of carring SV40 enhancer element
01/05/2005CN1560249A Fibroblast growth factor-19 (FGF-19) nucleic acids and polypeptides and methods of use for the treatment of obesity
01/05/2005CN1560080A Corpuscles of stannius protein, stanniocalcin
01/05/2005CN1559615A Location controlled releasing method for ultrasonic microbubble contrast medium
01/05/2005CN1559607A Nucleic acid and protein composition and its production method and application in immune regulation
01/05/2005CN1559360A Method for planting esoderma/endothelial cell on inner surface of artificial blood vessel
01/05/2005CN1183250C Virus with specigic reproduction in tumor well and effective expression of tumor angiogenesis nihibitory factor and its construction method
01/05/2005CN1182874C Gene therapy for diabetic ischemic disease
01/04/2005US6838447 Immobilized nucleotide chargable particles
01/04/2005US6838446 Anticancer agents; genetic engineered enzyme
01/04/2005US6838444 Using nucleic acid; repair interior ear hair
01/04/2005US6838437 Inactivation resistant factor VIII
01/04/2005US6838428 A non-human mammal phenotype, vectors expressing the protein for treating respiratory system disease, viral diseases, purifying SP-D antibodies, enzyme inhibitor of metalloproteinase
01/04/2005US6838282 Polynucleotide that encodes a polypeptide; binding specificity; useful in bone marrow transplantation and gene therapy
01/04/2005US6838280 Containing iduronate-2-sulfatase gene; gene therapy
01/04/2005US6838279 DNA having a deletion in both copies of the LAT gene and ICP34.5 gene are inserted into the malignant cell
01/04/2005US6838273 Cloning and characterization of the FLBA gene of H. pylori, production of aflagellate strains
01/04/2005US6838272 Filtration process for separating viruses
01/04/2005US6838256 Coding sequences of the human BRCA1 gene
01/04/2005US6838240 Detection of blooms disease; obtain tissue sample, incubate with probe which hybridizes to gene associated with blooms disease, the abence of wildtype gene indicates disease
01/04/2005US6838079 Methods for using the obese product to stimulate hematopoietic development
01/04/2005CA2288341C Erythropoietin in the treatment of domestic and livestock animals for anemia
01/04/2005CA2283509C Novel bicyclonucleoside and oligonucleotide analogue
12/2004
12/30/2004US20040268425 use to treat glycosaminoglycan associated pathologies such as eye disorders or tumors; sialated and pegylated forms of a recombinant sHASEGP to enhance stability and serum pharmacokinetics over naturally occurring slaughterhouse enzymes; transgenic animals; dosage forms
12/30/2004US20040267004 nucleic acid that binds to high mobility group protein-I (HMG-I), and causes presenilin-2 gene exon 5-lacked type aberrant splicing by the association with the HMG-I protein; an inhibitor for inhibiting a binding between protein-nucleic acid caused by aberrant splicing; drug screening; antisense agents
12/30/2004US20040267003 Nucleotide and amino aicd sequences of oocyte factors for altering ovarian follicular growth in vivo or in vitro
12/30/2004US20040266994 Type-1 ribosome-inactivating protein
12/30/2004US20040266990 Cd109 nucleic acid molecules polypeptides and methods of use
12/30/2004US20040266720 Splice-region antisense composition and method
12/30/2004US20040266717 Administering polynucleotide capable of modulating an electrical property in a standard cardiac electrophysiological assay; expressing the polynucleotide in the mammal to prevent or treat the cardiac arrhythmia
12/30/2004US20040266716 Administering polynucleotide capable of modulating an electrical property in a standard cardiac electrophysiological assay; expressing the polynucleotide in the mammal to prevent or treat the cardiac arrhythmia
12/30/2004US20040266715 Neurite regeneration
12/30/2004US20040266714 Modulate gene expression; diagnosis, therapy of disease; antidiabetic agents; insulin resistance
12/30/2004US20040266713 Using nucleic acids; antitumor agents
12/30/2004US20040266712 Selective inhibition of vascular smooth muscle cell proliferation
12/30/2004US20040266706 Cross-linked oligomeric compounds and their use in gene modulation
12/30/2004US20040266694 Angiogenesis inhibitor induced by vascular endothelial growth factor
12/30/2004US20040266682 administering gastrin/(cholecystokinin (CCK) receptor ligand and a factor for complementing gastrin for islet neogenesis therapy; sustained release; for expanding a functional beta cell mass of pancreatic islet transplants; reduces amount of stem cells necessary for treatment; kits
12/30/2004US20040266004 Method of promoting nucleic acid transfer
12/30/2004US20040266003 Using bacterial small membrane vessicles as tools for transfer of heterologous nucleotide sequences into cells
12/30/2004US20040265999 Use of antisense oligonucleotides to inhibit the expression of human Akt-1
12/30/2004US20040265968 Tissue plasminogen activator-like protease
12/30/2004US20040265967 14790, a novel protein kinase molecule and uses therefor
12/30/2004US20040265913 Tumor necrosis factors (TNF); humanized/chimeric monoclonal antibodies; fab fragments; hybridomas, host cells, Chinese Hamster Ovary cells
12/30/2004US20040265898 C-type lectin transmembrane antigen expressed in human prostate cancer and uses thereof
12/30/2004US20040265890 a polypeptide of given amino acid sequence; use as drug target for gastrointestinal disorders; fusion proteins; diagnosis
12/30/2004US20040265885 Peptide nucleic acid (PNA) derivatives which carry one or more phosphoryl radicals at the N terminus of the PNA backbone; can be purified using efficient methods such as chromatography or electrophoresis; use as pharmaceuticals and diagnostic agents
12/30/2004US20040265872 nucleotide sequences for polypeptides of the riboflavin specific deaminase family, "ribG"; drug target for use screening for antibacterials; vectors, host cells
12/30/2004US20040265856 5' portion of an intestinal lactase-phlorizine hydrolase (LPH) gene; point mutations; solid phase synthesis; immunoassay; vectors; primers; host cells; antibodies; kits; gene therapy
12/30/2004US20040265852 Diangnosis and treatment of AUR1 and/or AUR2 related disorders
12/30/2004US20040265848 Circovirus sequences associated with piglet weight loss disease (PWD)
12/30/2004US20040265839 Gene knockout; gene overexpression; liposomes; fusion proteins; immunoglobulins; FC fragments; glutathione S-transferase (GST) polypeptides