Patents
Sitemap › A61 - Medical or veterinary science; Hygiene › A61K - Preparations for medical, dental, or toilet purposes › A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
12/2005
12/22/2005WO2005120581A2 Gene therapy for neurometabolic disorders
12/22/2005WO2005120580A2 Compositions and methods for treatment of fibro-proliferative disorders
12/22/2005WO2005120579A1 Freeze-dried composition of inactivated virus envelope with membrane fusion activity
12/22/2005WO2005120566A1 Dendrite cells transduced with recombinant adenovirus advcea which generate cea-specific cytotoxic t lymphocytes, vaccine and pharmaceutical composition comprising the same
12/22/2005WO2005120527A1 Use of lactic acid bacteria for decreasing gum bleeding and reducing oral inflammation
12/22/2005WO2005120520A2 Compositions and methods for diagnosis and treatment of chemotherapy-resistant neoplastic disease
12/22/2005WO2005120469A1 Lipid nanoparticles as vehicles for nucleic acids, process for their preparation and use
12/22/2005WO2005120152A2 Cationic lipids and methods of use
12/22/2005WO2005081847A3 Potent mucosal immune response induced by modified immunomodulatory oligonucleotides
12/22/2005WO2005078096A3 Dual functional oligonucleotides for use in repressing mutant gene expression
12/22/2005WO2005046621A3 Enhancement of vaccine-induced immune responses and protection by heterologous boosting with alphavirus replicon vaccines
12/22/2005WO2005033269A3 Methods for inducing an immune response via oral administration of an adenovirus
12/22/2005WO2005020892B1 Pharmaceutical compositions and methods for metabolic modulation
12/22/2005WO2005001030A3 Markers for pre-cancer and cancer cells and the method to interfere with cell proliferation therein
12/22/2005WO2004111191A3 Methods and compositions for controlling efficacy of rna silencing
12/22/2005WO2004111074A3 In vivo production of a clostridial neurotoxin light chain peptide
12/22/2005WO2004085623A3 A compact synthetic expression vector comprising double-stranded dna molecules and methods of use thereof
12/22/2005WO2004058159A3 Branched immunomodulatory compounds and methods of using the same
12/22/2005US20050283844 Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
12/22/2005US20050282999 Beta-amyloid peptide-binding proteins and polynucleotides encoding the same
12/22/2005US20050282767 Inhibitors of epoxide hydrolases for the treatment of hypertension
12/22/2005US20050282766 Compositions and methods for treating neoplastic disease using chemotherapy and radiation sensitizers
12/22/2005US20050282765 Enzyme having S-adenosyl-L-homocysteine hydrolase (AHCY) type activity
12/22/2005US20050282764 Method of identifying nucleic acid compositions for muting expression of a gene
12/22/2005US20050282763 Methods of treating bladder disorders
12/22/2005US20050282762 Antisense oligonucleotides for treating atopic diseases and neoplastic cell proliferation
12/22/2005US20050282761 Modulation of growth hormone receptor expression and insulin-like growth factor expression
12/22/2005US20050282760 Antisense modulation of ptpn12 expression
12/22/2005US20050282733 Differentiation modulating agents and uses therefor
12/22/2005US20050282280 Oncolytic adenoviral vectors encoding GM-CSF
12/22/2005US20050282275 Adipose-derived stem cells and lattices
12/22/2005US20050282272 inducing a reduced lymphocyte proliferative response to a Major Histocomatibilty Complex (MHC) type presented on an human embryonic stem (hES) cell in a subject; induces a state of inflammatory quiescence or immune unresponsiveness, which in turn enhances engraftment of the stem cells
12/22/2005US20050282255 Cell growth differentiation factor (MP52) for use in treatment and prevention of nervous system, dental, skin, connective tissue and bone disorders; wound healing agents
12/22/2005US20050282217 Using TR10 polypeptide, which is a member of the tumor necrosis factor (TNF) receptor superfamily for inhibiting apoptosis associated with HIV infection
12/22/2005US20050282216 Purified polypeptides having IL-13 receptor activity
12/22/2005US20050282203 Caged RNAs and methods of use thereof
12/22/2005US20050282188 RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)
12/22/2005US20050282165 Diagnosis of Carcinoma Using RAIG1 Polypeptides
12/22/2005US20050282163 Polymorphisms in elastin, fibrillin and related genes as predisposing to restenosis and to a therosclerosis
12/22/2005US20050282157 Using oligonucleotide and peptide nucleic acid oligomers for use as diagnostic tool in monitoring cytosine methylation; detecting cell proliferative, inflammatory, connective, bone, nervous system and cardiovascular disorders
12/22/2005US20050282150 Identifying an inhibitor of cyclin E2 polypeptide/cyclic-dependent kinase-2 complex formation by allowing a cyclin E2 polypeptide having a specific sequence and cdk2 to spontaneously associate to form a cyclin E2 polypeptide/cdk2 complex; adding test compound; and assaying for a decrease in complex
12/22/2005US20050281861 Macromolecule-containing sustained release intraocular implants and related methods
12/22/2005US20050281835 Polypeptide and polynucleotide of given sequences; monoclonal antibody binding to antigen Ag473; use in vaccines and diagnosis
12/22/2005US20050281812 Antibodies to insulin-like growth factor I receptor
12/22/2005US20050281804 Administering human recombinant alpha -L-iduronidase, carrier and polysorbate for therapy of mucopolysaccharidosis
12/22/2005US20050281791 Method for inducing cardiac myocytes in embryonic stem (ES) cells by induction with precardiac endoderm and mesoderm
12/22/2005US20050281787 Tumor-specific vector for gene therapy
12/22/2005US20050281786 AAV mediated gene delivery to cochlear cells
12/22/2005US20050281785 Method of reducing side effects of cancer therapy using p53 recombinant adenovirus
12/22/2005US20050281784 Methods for administering recombinant adeno-associated virus virons to humans previously exposed to adeno-associated virus
12/22/2005US20050281783 Listeria-based EphA2 vaccines
12/22/2005US20050281782 Novel recombinant poxvirus composition and uses thereof
12/22/2005US20050281781 extracted yeast cell wall comprising beta-glucan, a payload molecule(e.g.polynucleotides, polypeptides, proteins, and drugs) and a payload trapping molecule ( e.g polysaccharides, polyamides, polyacrylamide, cationic and anionic polymers, detergents); both in vivo/in vitro delivery of polyload molecule
12/22/2005US20050281780 Contacting, by ductal cannulation, the ductal epithelium of the exocrine gland with a cytolytic virus to destroy less than all of the ductal epithelium so as to inhibit formation of cancer of ductal epithelial origin
12/22/2005US20050281779 Enhancing immune responses to genetic immunization by using a chemokine
12/22/2005US20050281756 Use of lactic acid bacteria for decreasing gum bleeding and reducing oral inflammation
12/22/2005CA2609260A1 Rna-containing microvesicles and methods therefor
12/22/2005CA2569664A1 Lipid encapsulated interfering rna
12/22/2005CA2569645A1 Cationic lipids and methods of use
12/22/2005CA2569419A1 Double strand compositions comprising differentially modified strands for use in gene modulation
12/22/2005CA2568995E Construction of oncolytic adenovirus recombinant specifically expressing immune modulatory factor gm-csf in tumor cells and uses thereof
12/22/2005CA2568735A1 Double strand compositions comprising differentially modified strands for use in gene modulation
12/22/2005CA2567877A1 Polynucleotides encoding acetylcholine-gated chloride channel subunits of caenorhabditis elegans
12/21/2005EP1607402A1 Method for the diagnosis of tumour
12/21/2005EP1607384A1 Novel functional peptide nucleic acid and process for producing the same
12/21/2005EP1606630A2 Diagnostics and therapeutics for diseases associated with dopamine receptor d4 (drd4)
12/21/2005EP1606411A1 Mutant vesicular stomatitis viruses and use thereof
12/21/2005EP1606408A2 Human p53 splice variant displaying differential transcriptional activity
12/21/2005EP1606407A2 Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure
12/21/2005EP1606305A2 Nucleic acid compounds for inhibiting angiogenesis and tumor growth
12/21/2005EP1606302A2 Methods and compositions for using suramin, pentosan polysulfate, telomerase antisense, and telomerase inhibitors
12/21/2005EP1605978A2 Therapeutic compositions
12/21/2005EP1605965A1 Use of saposin-related proteins for preventing and treating obesity, diabetes and/or metabolic syndrome
12/21/2005EP1605961A2 Polypeptide compounds for inhibiting angiogenesis and tumor growth
12/21/2005EP1576086A3 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
12/21/2005EP1341904B1 Zipper protein kinase and uses thereof
12/21/2005EP1218518B1 Dna polymerase lambda and uses thereof
12/21/2005EP1119581B1 USE OF A VECTOR EXPRESSING RB2/p130 FOR PREVENTION OR TREATMENT OF RESTENOSIS OR ATHEROSCLEROTIC PLAQUES
12/21/2005EP0994947B1 Mu-1, member of the cytokine receptor family
12/21/2005EP0920524B1 A short-shafted adenoviral fiber and its use
12/21/2005EP0809705B1 Nucleic acid-containing composition, preparation and use thereof
12/21/2005EP0783573B1 Method of enhancing expression of mhc class i molecules bearing endogenous peptides
12/21/2005EP0698108B2 Adenoviral vectors of animal origin and use thereof in gene therapy
12/21/2005EP0680331B1 Recombinant virus immunotherapy
12/21/2005CN1232643C Nucleic acid vaccine
12/21/2005CN1232641C Modulator for function of receptor of TNF/NGF receptor family and other protein
12/21/2005CN1232306C Adjustable controllable tumor living vaccine and its preparation method
12/21/2005CN1232303C Use of gene NMESI related to esophageal carcinoma and encoded polypeptide
12/20/2005US6977296 Human cervical cancer suppressor protein, polynucleotide encoding the protein, cell transformed with the polynucleotide and method for suppressing proliferation of cancer cell using the expression vector
12/20/2005US6977245 Oligodeoxynucleotide and its use to induce an immune response
12/20/2005US6977244 Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides
12/20/2005US6977174 Circular DNA molecule with conditional origin of replication, method for preparing the same and use thereof in gene therapy
12/20/2005US6977158 Mammalian IAP gene family, primers, probes, and detection methods
12/20/2005US6977144 Nucleic acids encoding Selected Interacting Domain (SID registered) polypeptides binding selectively to a peptide encoded by a pathogenic strain of the hepatitis C virus; genetic engineering; gene therapy; bactericides;
12/15/2005WO2005118840A2 Diagnostics and therapeutics for diseases associated with kallikrein 10 (klk10)
12/15/2005WO2005118825A2 Chimeric adenoviruses for use in cancer treatment
12/15/2005WO2005118811A1 Novel polypeptide useful for diagnosis and treatment of cancer
12/15/2005WO2005118802A2 Targeting pseudotyped retroviral vectors
12/15/2005WO2005118789A2 Therapeutic delivery of adenosine into a tissue
12/15/2005WO2005118016A1 Medical device comprising a biologically active agent
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