Patents
Sitemap › A61 - Medical or veterinary science; Hygiene › A61K - Preparations for medical, dental, or toilet purposes › A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
12/2005
12/29/2005WO2003068155A3 Inhibition of vegf receptor signaling reverses tumor resistance to radiotherapy
12/29/2005WO2002099040A3 Igs as modifiers of the p53 pathway and methods of use
12/29/2005US20050289660 Cyclic amp phosphodiesterase 4d7 isoforms and methods of use
12/29/2005US20050289658 System for regulating in vivo the expression of a transgene by conditional inhibition
12/29/2005US20050289657 Diagnostic and therapeutic use of an atp-binding cassette gene and protein for neurodegenerative diseases
12/29/2005US20050288651 Apparatus with weeping tip and method of use
12/29/2005US20050288487 Human mast cell-expressed membrane proteins
12/29/2005US20050288248 Polypeptide; polyethylene glycolylated polypeptide; antidiabetic agents; side effect reduction
12/29/2005US20050288247 Inducible inactivation of synaptic transmission
12/29/2005US20050288246 Enhance cellular uptake of uncharged antisense oligonucleotide; forming a conjugate and arginine-rich peptide; oligonucleotide includes a string of contiguous guanine bases; substitute inosine base to limit the number of contiguous guanine bases to three; cancer, polycystic kidney disease, restenosis
12/29/2005US20050288245 Reducing flavivirus or Hepatitis virus replication in vitro or vivo by inhibiting activity of a microRNA; administering an antisense oligonucleotide complementary to microR-122
12/29/2005US20050288244 RNA interference; microRNA; improved pharmacokinetics
12/29/2005US20050288243 Methods and compositions for treating gain-of-function disorders using RNA interference
12/29/2005US20050288242 RNA interference mediated inhibition of RAS gene expression using short interfering nucleic acid (siNA)
12/29/2005US20050288241 encoding novel polypeptides, called "NOVX" nucleic acid sequences; vectors and host cells; wide variety of therapeutic and diagnostic uses; drug targets or therapeutic use; encode proteins such as NOV15 of the MEGF/Fibrillin family of proteins which have epidermal growth factor (EGF)-like motifs
12/29/2005US20050288225 Modulators of intracellular inflammation, cell death and cell survival pathways
12/29/2005US20050287671 Soluble steroidal peptides for nucleic acid delivery
12/29/2005US20050287667 Methods and compositions for the inhibition of gene expression
12/29/2005US20050287657 Method for producing recombinant adenovirus
12/29/2005US20050287584 Secreted proteins encoded by human chromosome 13
12/29/2005US20050287579 Genes for male accessory gland proteins in Drosophila melanogaster
12/29/2005US20050287571 determining the amount of defensin bound to sperm and comparing with a standard control, wherein a decrease in the amount from the standard control indicates a decrease in fertility in the male
12/29/2005US20050287565 Methods, compositions and compound assays for inhibiting amyloid-beta protein production
12/29/2005US20050287558 SNPs of apolipoprotein B and modulation of their expression
12/29/2005US20050287545 Protein belonging to the TNF superfamily involved in signal transduction, nucleic acids encoding same, and methods of use thereof
12/29/2005US20050287530 TCL-1b gene and protein and related methods and compositions
12/29/2005US20050287521 Oligonucleotides from sequences coding for the surface component of ptlv envelope proteins and uses thereof
12/29/2005US20050287519 Methods, compositions and compound assays for inhibiting amyloid-beta protein production
12/29/2005US20050287202 Compound
12/29/2005US20050287168 Recombinant spores
12/29/2005US20050287165 Meningococcal antigens
12/29/2005US20050287162 Recombinant fowlpox virus
12/29/2005US20050287159 Treatment methods for eotaxin mediated inflammatory conditons
12/29/2005US20050287157 Dry formulation for transcutaneous immunization
12/29/2005US20050287148 Monoclonal antibody 1A7 and use for the treatment of melanoma and small cell carcinoma
12/29/2005US20050287144 For the modulation of signal activities controlled by NF-kappa B-inducing kinase (NIK); cancer , rheumatoid arthritis, osteoarthritis, inflammatory bowel disease, asthma, cardiac infarct, Alzheimer's disease, or atherosclerosis
12/29/2005US20050287143 antibodies against such VEGFs, which may be used to inhibit their action, for example, to inhibit the growth of tumors, to treat diabetic retinopathy, rheumatoid arthritis and psoriasis
12/29/2005US20050287142 Remedies or preventives for rheumatoid arthritis
12/29/2005US20050287139 Wound healing
12/29/2005US20050287133 Precursor N-acetylgalactosamine-4 sulfatase, methods of treatment using said enzyme and methods for producing and purifying said enzyme
12/29/2005US20050287132 Biliverdin reductase fragments and variants, and methods of using biliverdin reductase and such fragments and variants
12/29/2005US20050287129 Vectors and methods for long-term immune evasion to prolong transplant viability
12/29/2005US20050287128 RNA interference mediated inhibition of TGF-beta and TGF-beta receptor gene expression using short interfering nucleic acid (siNA)
12/29/2005US20050287127 Use of stem cells to generate inner ear cells
12/29/2005US20050287123 DNA vaccines encoding CEA and a CD40 ligand and methods of use thereof
12/29/2005US20050287122 Adeno-associated virus vectors with modified capsid proteins for use as gene transfer and proliferation tools; gene therapy; genetic vaccines
12/29/2005US20050287121 Methods, compositions and compound assays for inhibiting amyloid-beta protein production
12/29/2005US20050287120 Cancer - targeted viral vectors
12/29/2005US20050287119 Treating a superficial interferon-resistant tumor of the bladder by contacting the tumor with Syn 3 and a replication-deficient adenoviral recombinant vector encoding an interferon alpha, where the vector and Syn3 are instilled intravesically; interferon alpha 2b,2a,2 or 1
12/29/2005US20050287118 Bacterial plasmid with immunological adjuvant function and uses thereof
12/29/2005US20050287116 Use in suicide gene therapy of cancer cells and producing immunotoxins; infecting the cell with an adenovirus produced by a packaging cell line, where an adenoviral vector of a promoter is linked to a nucleic acid encoding the A subunit of diphtheria toxin A or Pseudomonas Exotoxin A, mutated EF-2 gene
12/29/2005US20050287110 Cationic graft-compolymer for non-viral gene delivery vector
12/29/2005DE102004026309A1 Pharamzeutische Zusammensetzung zur Behandlung allergischer Erkrankungen, pathologischer Atemswegsveränderungen und von Krebs durch Modulation der Genexpression des Stat6 Pharamzeutische composition for the treatment of allergic diseases, pathological airway changes and cancer through modulation of gene expression of Stat6
12/29/2005CA2572171A1 Use of dna molecule as vaccine adjuvant
12/29/2005CA2570510A1 Porcine sulfotransferase 2a1 polynucleotide sequence, protein, and methods of use for same
12/29/2005CA2570017A1 Combination treatment of cancer with elicitor of gene product expression and gene-product targeting agent
12/29/2005CA2568643A1 Treatment of non alcoholic steatotic hepatitis (nash)
12/28/2005EP1609864A2 Use of neuronal apoptosis inhibitor protein (NAIP)
12/28/2005EP1609863A2 Secreted and transmembrane polypeptides and nucleic acids encoding the same
12/28/2005EP1609857A1 Method of demethylating target methylated region of genomic dna
12/28/2005EP1609482A1 Drug for treating hemophilia and method of treating hemophilia using the same
12/28/2005EP1608763A2 Compounds and methods to enhance raav transduction
12/28/2005EP1608755A2 Tak1-mediated inhibition of osteogenesis
12/28/2005EP1608753A1 Antisense oligonucleotides (odn) against smad7 and uses in medical field thereof
12/28/2005EP1608735A2 Irna conjugates
12/28/2005EP1608679A1 Dystrophin-related protein (drop1), a marker for carcinomas
12/28/2005EP1608411A2 Stem-cell, precursor cell, or target cell-based treatment of multi-organ failure and renal dysfunction
12/28/2005EP1608410A2 Pharmico-gene theraphy of epithelial sodium channel associated disoders
12/28/2005EP1608409A2 Peptides selectively lethal to malignant and transformed mammalian cells
12/28/2005EP1608390A2 Correlation of gene expression with chromosome abnormalities in ataxia telangiectasia tumorigenesis
12/28/2005EP1608316A2 Methods and compositions for treating and preventing inflammatory conditions
12/28/2005EP1490013A4 Methods, compositions, and kits for enhancing oligonucleotide-mediated nucleic acid sequence alteration using compositions comprising a histone deacetylase inhibitor, lambda phage beta protein, or hydroxyurea
12/28/2005EP1335987B1 Modified vaccinia ankara virus variant
12/28/2005EP1274454B1 Methods and compositions for eliciting an immune response
12/28/2005EP1073683B1 G-csf receptor agonist antibodies and screening method therefor
12/28/2005EP1053302B1 Expanded and genetically modified populations of human hematopoietic stem cells
12/28/2005EP0940467B1 Promoters for swine complement inhibitors
12/28/2005EP0920534B1 Mutations in the diabetes susceptibility genes hepatocyte nuclear factor (hnf) hnf-1alpha, hnf-1beta and hnf-4alpha
12/28/2005EP0879281B1 Methods for transforming dendritic cells and activating t cells
12/28/2005EP0797676B1 Recombinant adenoviral vector and methods of use
12/28/2005EP0742834B9 Method of preparing a viral vector of at least 20kb by intermolecular recombination in a procaryotic cell
12/28/2005EP0672159B1 Homologous sequence targeting in eukaryotic cells
12/28/2005CN1714151A Novel glutamate receptor modulatory proteins and nucleic acid molecules and uses therefor
12/28/2005CN1712070A Production of gene carrier and use thereof
12/28/2005CN1233831C SiRNA and expression plasmid for inhibiting human bc1-2 gene expression and their use for preparing medicine
12/28/2005CN1233421C Plasmid for gene therapy of cardiac muscle
12/27/2005US6979677 Inhibition of vascular smooth muscle cell proliferation
12/27/2005US6979568 Vector for the expression of two foreign genes
12/27/2005US6979555 Hyaluronan receptor for endocytosis
12/27/2005US6979539 Regulation of endogenous gene expression in cells using zinc finger proteins
12/22/2005WO2005121377A2 Methods and compositions for identifying compounds that inhibit hiv-1 subunit-specific reverse transcriptase
12/22/2005WO2005121372A2 Double strand compositions comprising differentially modified strands for use in gene modulation
12/22/2005WO2005121371A2 Double strand compositions comprising differentially modified strands for use in gene modulation
12/22/2005WO2005121370A2 Oligomeric compounds that facilitate risc loading
12/22/2005WO2005121348A1 Lipid encapsulated interfering rna
12/22/2005WO2005121343A1 Construction of oncolytic adenovirus recombinant specifically expressing immune modulatory factor gm-csf in tumor cells and uses thereof
12/22/2005WO2005121339A1 Polynucleotides encoding acetylcholine-gated chloride channel subunits of caenorhabditis elegans
12/22/2005WO2005121320A1 Autonomouos replication promoter for stem cells
12/22/2005WO2005120583A2 Method for preventing or treating cardiac hypertrophy
12/22/2005WO2005120582A2 Compositions and methods for inhibiting expression of hypoxia-inducible genes
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