Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
08/2008
08/09/2008CA2618099A1 Antagonists of a non-selective cation channel in neural cells
08/07/2008WO2008094866A1 Methods and compositions for transermal delivery of nucleotides
08/07/2008WO2008094860A2 Treating ocular diseases using peroxisome proliferator-activated receptor delta antagonists
08/07/2008WO2008093152A1 Obligate heterodimer meganucleases and uses thereof
08/07/2008WO2008092262A1 Methods and compounds for treatment, prevention and diagnosis of parasitic infection and disease
08/07/2008WO2008074328A3 Microrna target site blocking oligos and uses thereof
08/07/2008WO2008066658A9 Engineered cellular pathways for programmed autoregulation of differentiation
08/07/2008WO2008030560A3 Hsv-1 and hsv-2 vaccines and methods of use thereof
08/07/2008WO2008021160A3 Regulation of litaf modulated cytokine production by a novel p53 short peptide
08/07/2008WO2008021136B1 Methods and sequences to suppress primate huntington gene expression in vivo
08/07/2008WO2008016924A3 Identification of a micro-rna that activates expression of beta-myosin heavy chain
08/07/2008WO2007147168A3 Attenuation of hyperoxia-induced cell death with mitochondrial aldehyde dehydrogenase
08/07/2008US20080188648 siRNA targeting human hairless protein (HR)
08/07/2008US20080188647 siRNA targeting DNA-damage-inducible transcript 4 (DDIT4)
08/07/2008US20080188436 Intact Minicells as Vectors for DNA Transfer and Gene Therapy In Vitro and In Vivo
08/07/2008US20080188432 Short nucleotide subsequences located within number 15; such as locked nucleic acids antisense oligonucleotides; biostability, cell permeability; anticancer agents
08/07/2008US20080188431 Delivery of heterologous nucleic acid into epithelial cells of gut, lung, genitourinary tract, kidney, blood vessels and/or across blood brain barrier without direct injection
08/07/2008US20080188417 Beta-like glycoprotein hormone polypeptide and heterodimer
08/07/2008US20080187997 Novel lentiviral packaging cells
08/07/2008US20080187993 Coupling antisense angents to reverse TAT polypeptide to enhance uptake into activated macrophage and/or lymphocytes; prevention and treatment of human immunodeficiency viral infection
08/07/2008US20080187968 For eukaryotic in vitro expression; silicone-based surfactants and microcapsules; phage display
08/07/2008US20080187576 Osteoarthritis; rheumatic diseases; gene therapy; interleukin receptor antagonist peptide or polypeptide
08/07/2008US20080187556 Using human rabies virus immunoglobulins; viricide against human papillomarvirus; side effect reduction; antiaging and oxidation resistance
08/07/2008US20080187551 Nucleotide sequences coding oncogenic polypeptides for use in generating vaccines to prevent and treat cell proliferative disorders; genetic vaccines
08/07/2008US20080187543 Using antimyostatin immunoglobulin to improving tissue wound healing
08/07/2008US20080187541 Helicobacter pylori adhesin binding group antigen
08/07/2008US20080187538 Posh nucleic acids, polypeptides and related methods
08/07/2008US20080187537 Using immunodeficient animals to generate cancer cell infiltrating lymphocytes; immunotherapy; tissue targeted therapy
08/07/2008US20080187520 Expression vector comprising nucleotide sequences coding cytotoxic exoenzyme fusion for use as tool in development of vaccine which prevent pseudomonal infection; genetic vaccines
08/07/2008US20080187519 Varing hydrogen ion concentration in presence of chelate agents, centrifuging and recovering detach cells from physical surface; generating single cell suspension; tissue engineering
08/07/2008US20080187494 Inducing/ enhancing the induction of differentiation of stem cells into embryonic germ layer by culturing the stem cells in the presence of a defined medium free of xeno- and serum-components, of defined factors that contribute to the promotion of differentiation to embryonic germ layer derivatives
08/07/2008DE102007040718B3 Use of oligonucleotides with defined sequences to reduce mouse major satellite transcription
08/07/2008CA2677177A1 Obligate heterodimer meganucleases and uses thereof
08/07/2008CA2675378A1 Chitosan-based colloidal particles for rna delivery
08/06/2008EP1953243A2 Polynucleotides related to colon cancer
08/06/2008EP1953173A1 Secreted and transmembrane polypeptides and nucleic acids endoding the same
08/06/2008EP1951891A1 Cancer antigen mage-a9 and uses thereof
08/06/2008EP1951865A1 Stabilizing formulations for recombinant viruses
08/06/2008EP1951751A1 Gene therapy for renal failure
08/06/2008EP1951317A1 A pharmaceutical composition for treating malignant tumors containing human p31 genes
08/06/2008EP1951306A2 Reduction and prevention of cell-associated hiv transepithelial migration, microbides and other formulations and methods
08/06/2008EP1449920B1 Trangenic mice used as model for human pathologies originating from stem cells
08/06/2008EP1377671B1 Oncolytic adenoviral vectors
08/06/2008EP1366059B1 Methods and compositions for modulating gluconeogenesis using pgc-1
08/06/2008EP1326879B1 Nucleic acid constructs and cells, and methods utilizing same for modifying the electrophysiological function of excitable tissues
08/06/2008EP1257298B1 Cosmid dna constructs and methods of making and using the same
08/06/2008EP1204739B1 Enhancement of expression of a single-stranded, heterologous nucleotide sequence from recombinant viral vectors by designing the sequence such that it forms intrastrand base pairs
08/06/2008EP1147133B1 Peptides consisting of two PTH functional domains fused by a linker molecule, and derivatives thereof
08/06/2008EP1108034B1 Attenuated salmonella spi2 mutants as antigen carriers
08/06/2008EP0928339B1 Mammalian artificial chromosomes
08/06/2008EP0870047B1 Episomal vector and uses thereof
08/06/2008EP0832109B1 Fibroblast growth factor homologous factor-2 and methods of use
08/06/2008EP0666911B9 Multidrug resistance gene
08/06/2008CN101238218A Transduction of primary cells
08/06/2008CN101238214A Treatment of disease using an improved regulated expression system
08/06/2008CN101237884A Int6 protein involved in hypoxia stress induction and use thereof
08/06/2008CN101235387A Adenoids viral vectors for constructing endogenesis promoter to regulate and control exogenous gene
08/06/2008CN101235386A Fowl infectious bronchitis virus N gene and fowl IL-18 gene coexpression DNA bacterin pIRES-N/IL18
08/06/2008CN101235385A Fowl infectious bronchitis virus M gene and fowl IL-2 gene coexpression DNA bacterin pIRES-M/IL2
08/06/2008CN101235375A Chicken interleukins 16 gene and its eukaryon expression plasmid construction and immunity effect
08/06/2008CN101235374A Chicken interleukins 1beta gene and its eukaryon expression plasmid construction and immunity effect
08/06/2008CN101235373A RG gene sequence for diffusivity large B cell lymphoma correlation antigen specific TCR Vbeta13 subfamily and application thereof
08/06/2008CN101235365A Highly effective method for producing adenovirus
08/06/2008CN101235079A Short peptide for inhibiting growing of liver cancer cell and application thereof
08/06/2008CN100408682C MUC-1 antigen with reduced number of VNTR repeat units
08/06/2008CN100408677C Method for genetically modifying and inducing intracerebral transplantation mesenchymal stem cells to be differentitated into neuron
08/06/2008CN100408101C Gene therapy for critical limb ischemia with wild type or mutant eNOS
08/05/2008US7408046 Administering anticarcinogenic agent and chelate complex of macrocyclic aminophosphonic acid and radionuclide such as samarium ethylenediaminetetramethylenephosphonic acid (EDTMP) to replace total body irradiation;antiproliferative agents; autoimmune, infectious, metabolic or genetic disorders
08/05/2008US7407947 liposomes containing a sterol skeleton based compound wherein one or several amphoteric groups with an isoelectric point of between 4 and 9 are substituted on the 3rd position of the ring system
08/05/2008US7407943 Comprises oligonucleotide which targets apolipoprotein nucleotide sequences and prevents expression; gene expresion inhibition; diagnosis and treatment of cardiovascular, infectious, hyperlipidemic and atherosclerotic disorders
08/05/2008US7407803 Immunogenic composition comprising bacterial or viral vector, antigen and toxins; escherichia and baculovirus; vaccines
08/05/2008US7407801 Nucleic acid encoding CFTR (cystic fibrosis transmembrane conductance regulator) protein of cytomegalovirus (CMV); gene therapy for genetic and metabolic disorders; expression in adenoviral-infected nasal epithelium
08/05/2008US7407792 Compositions, organisms and methodologies employing a novel human kinase
08/05/2008US7407790 Recombinant double-stranded RNA phages and uses thereof
08/05/2008US7407771 modulation of apoptosis or inflammatory processes, by transfection of cells with nucleotide sequences that code for proteins, fragments or isoforms capable of binding to or interacting directly or indirectly with death domains and/or binding proteins
08/05/2008US7407751 Methods for the detection and prognosis of breast tumors
08/05/2008CA2343575C Inhibition of smooth muscle cell migration by heme oxygenase 1
08/05/2008CA2340888C Novel tumor antigen protein sart-3 and tumor antigen peptide thereof
08/05/2008CA2259640C Human glycine transporter
07/2008
07/31/2008WO2008092153A2 Modification of exosomal components for use as a vaccine
07/31/2008WO2008092142A2 Rnai-mediated inhibition of aquaporin 1 for treatment of ocular neovascularization
07/31/2008WO2008092099A2 Compositions and methods for treating hematopoietic malignancies
07/31/2008WO2008092081A2 Targeted delivery of sirna
07/31/2008WO2008092002A2 Compositions and methods for treating and diagnosing pancreatic cancer
07/31/2008WO2008091710A2 Methods and compositions for treating neuropathies
07/31/2008WO2008091703A2 Chemically modified oligonucleotides for use in modulating micro rna and uses thereof
07/31/2008WO2008091680A2 Methods for controlling stem cell differentiation
07/31/2008WO2008091465A2 Peg and targeting ligands on nanoparticle surface
07/31/2008WO2008091171A1 A transgenic animal and a method of producing it
07/31/2008WO2008090850A1 Agent for enhancing the effect of anticancer agent
07/31/2008WO2008089645A1 Fusion polypeptide inhibiting cell growth and use thereof
07/31/2008WO2008073577A3 Electronic and biological pacemaker systems
07/31/2008WO2008035365A3 Rna interference mediated inhibition of aurorakinase b and its combinations as anticancer therapy
07/31/2008WO2006104609A3 Isolated myeloid-like bone marrow cell populations and methods of treatment therewith
07/31/2008US20080182981 Method and medicament for inhibiting the expression of a given gene
07/31/2008US20080182973 Enhance cellular uptake of uncharged antisense oligonucleotide; forming a conjugate and arginine-rich peptide; oligonucleotide includes a string of contiguous guanine bases; substitute inosine base to limit the number of contiguous guanine bases to three; cancer, polycystic kidney disease, restenosis
07/31/2008US20080182807 gene therapy against tumors and cancer; expression vector includes insert into tumor an effective amount of polynucleotides encoding a functionally active p53, express p53 to first DNA damaging agent, contact tumor cell with first DNA damaging agent, and kill tumor cell
07/31/2008US20080182788 Compositions and Methods for Increasing Bone Mineralization
07/31/2008US20080182777 Regulation of cell migration and adhesion
07/31/2008US20080182331 Production of transgenic animals; targeted replacement of an endogenous gene; genetic trait expression; DNA gene inactivation construct