Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
08/2008
08/26/2008US7417137 Tissue specific promoter for expression of a nucleic acid in a cancer cell, where expression is carcinoma selective; useful for tumor-selective suicide gene therapy
08/26/2008US7417136 Containing transcriptional units which encode a signal sequence of one flavivirus and an immunogenic flavivirus antigen of a second flavivirus; Japanese encephalitis virus (JEV), West Nile virus (WNV) or related flaviviruses
08/26/2008US7417130 DNA library comprising nucleotide sequences coding polypeptide containing leucine repeats for monitoring binding and regulation of ligand and cofactor interactions
08/26/2008US7417033 Antisense oligonucleotides capable of inhibiting the formation of capillary tubes by endothelial cells
08/26/2008US7416890 Baculovirus vector, method of producing thereof and method of gene transfer
08/26/2008US7416888 Cell lines
08/26/2008US7416887 Preparing viable stem cells in culture; prepare nutrient broth containing ligand and preferential receptor, inoculate with cells, monitor propagation and viability of cells
08/26/2008US7416855 Comprises nucleotide sequences coding enzymatic polypeptide associated with programed cell death for identifying modulators for treatment of inflammatory, neurodegenerative and cell proliferative disorders
08/26/2008US7416848 DNA encoding SNORF25 receptor
08/26/2008US7416730 Derivatives of the IL-2 receptor gamma chain, their production and use
08/26/2008US7416726 Cytotoxicity; therapeutic antibody
08/26/2008CA2441535C Methods for delivering nucleic acid molecules into cells and assessment thereof
08/26/2008CA2400007C Immunization of an individual against carcinoma and the preliminary stages thereof
08/26/2008CA2374667C Synthetic ligation reassembly in directed evolution
08/26/2008CA2331465C Improvements relating to encapsulation of bioactive agents
08/26/2008CA2289761C Method of making microencapsulated dna for vaccination and gene therapy
08/21/2008WO2008101233A2 Mitochondrial nucleic acid delivery systems
08/21/2008WO2008101219A2 Compositions and methods for inhibiting or reversing fibrotic disorders
08/21/2008WO2008101118A2 A gene expression signature identifying pro-angiogenic genes in ovarian tumor endothelial cell isolates
08/21/2008WO2008101087A1 Compositions and methods for modulation of pdx-1
08/21/2008WO2008100562A2 Indoleamine 2,3-dioxygenase, pd-1/pd-l pathways, and ctla4 pathways in the activation of regulatory t cells
08/21/2008WO2008100556A2 Alimentary protein-based scaffolds (aps) for wound healing, regenerative medicine and drug discovery
08/21/2008WO2008100555A2 Engineered lung tissue construction for high throughput toxicity screening and drug discovery
08/21/2008WO2008100230A1 Membrane(s) and uses thereof
08/21/2008WO2008099906A1 Therapeutic agent for periodontal disease and alveolar bone loss due to surgery
08/21/2008WO2008098569A2 Biologically active molecules, particularly based on pna and sirna, method for the cell-specific activation thereof, and application kit to be administered
08/21/2008WO2008080091A3 Activation of rig-i pathway
08/21/2008WO2008016996A3 Methods of modulating metabolic memory
08/21/2008WO2007134142A3 Methods and compositions for identifying and using p21-regulated proteins
08/21/2008US20080200663 Expression vector comprising nucleotide sequences coding fusion protein comprising HIV preintegration protein Vpr attached to amino or carboxy terminus of the Cre recombinase for use as genetic transfer tool in gene therapeutics
08/21/2008US20080200661 Composition for in vivo delivery
08/21/2008US20080200568 Screening for non-insulin dependent diabetes; using prostaglandin receptors, nitric oxide synthase, caspase, integrins targets; reacting with thrombospondin or metalloprotease
08/21/2008US20080200420 Engineered RNA precursors encoded in plasmids and/or other vectors; simple, low cost technique utilizing DNA molecule production; host cells, transgenes
08/21/2008US20080200419 Deletion and frame shift mutation; protecting hematopoietic stem cells from cytotoxic stress; enhancing maintenance in vitro during retroviral transduction; slowing aging; leukemia, solid tumors, genetic disorders
08/21/2008US20080200417 High efficiency encapsulation of charged therapeutic agents in lipid vesicles
08/21/2008US20080200414 HCaRG, A Novel Calcium-Regulated Gene
08/21/2008US20080200411 Modulating ATP gated ion channel P2X7R protein; administering agonistic agent; depression, anxiety, bipolar disorder
08/21/2008US20080200407 Suppress the immunoreactivity of a CpG motif and preventing and treating immune-mediated diseases such as arthritis
08/21/2008US20080200391 Stimulating differentiation in growth of osteoblasts and osteoclasts; wound healing of bone fractures and de novo bone formation; osteoporosis; bone cancer treatment; polynucleotide encoding polypeptide; genetic engineering
08/21/2008US20080200382 Inhibiting of the proliferation of tumor cells is mediated by upregulation of the activity of p53
08/21/2008US20080200377 Polyamideesters comprised of dicarboxylic acid and reaction product of diol and amino acid; drug delivery through blood vessels; controlled release, reduced adverse effects, inactivation protection, intracellular penetration enhanced pharmacological activity
08/21/2008US20080199917 Using vector comprising early gene modifications as genetic transfer element in gene therapy; gnentic vaccines
08/21/2008US20080199865 Using allelic variation in interleukin-1RN variable number of tandem repeats as diagnostic/prognostic indicator of decrease cell division and aging characteristics
08/21/2008US20080199529 Nanoparticle delivery vehicle
08/21/2008US20080199495 Administering hematopoietic stem cells for activation of gland; improve immunology response to leutinizing hormone- releasing hormone; antitumor, anticancwer agents
08/21/2008US20080199485 Method for enhancing T cell response
08/21/2008US20080199463 Method for treating multiple myeloma
08/21/2008US20080199442 Gene linked to control elements capable of directing in vivo transcription and translation; systemic delivery of erythropoietin
08/21/2008US20080199439 Displaces inhibitor of apoptosis proteins (IAP) from caspase; modification of light emission when bound to cell; selectively damages or kills neoplastic cells
08/21/2008US20080199438 Methods For Suppressing Tumor Proliferation
08/21/2008US20080199434 Compositions and methods for the treatment of cardiovascular conditions
08/21/2008US20080199433 Complementing cell lines
08/21/2008US20080199432 Role for sry in parkinson's disease
08/21/2008CA2677171A1 Transfection in magnetically driven continuous flow
08/21/2008CA2578493A1 A role for sry in parkinson's disease
08/20/2008EP1958964A2 RAB9A, RAB11A, and modulators thereof related to infectious disease
08/20/2008EP1958648A1 Therapeutic method for blood coagulation disorder
08/20/2008EP1958642A1 Regulation of cell growth by MUC1
08/20/2008EP1957648A2 Modulation of gene expression by oligomers targeted to chromosomal dna
08/20/2008EP1957646A1 Compositions and methods for therapy and diagnosis of cancer
08/20/2008EP1957112A2 Role of proteoglycans in drug dependence
08/20/2008EP1957100A1 Induction of mucosal tolerance to antigens
08/20/2008EP1654349A4 Sulfs as modifiers of the beta catenin pathway and methods of use
08/20/2008EP1651956A4 Melks as modifiers of the rac pathway and methods of use
08/20/2008EP1497440B1 Stable adenoviral vectors and methods for propagation thereof
08/20/2008EP1496944B1 Improved raav expression systems for genetic modification of specific capsid proteins
08/20/2008EP1446500B1 A method for regulating immune function in primates using the foxp3 protein
08/20/2008EP1333850B1 Use of il-13 inhibitors for the treatment of tumors
08/20/2008EP1232262B1 Recombinant gelatin in vaccines
08/20/2008EP1228210B1 A method for detecting prostate cancer
08/20/2008EP1142473B1 Compositions for acquiring immunological tolerance
08/20/2008EP1075493B1 Dna encoding snorf25 receptor
08/20/2008EP0826042B1 Genetic sequences and proteins related to alzheimer's disease, and uses therefor
08/20/2008EP0809704B1 Method for preparing a recombinant adenovirus genome
08/20/2008CN101247819A Methods for the treatment of anxiety and for identification of anxiolytic agents
08/20/2008CN101245352A Polygene interferential shRNA plasmid expression vector, construction method and application
08/20/2008CN101245350A Encoding nucleotide sequence of codons optimizing rotavirus protein, recombinant and uses thereof
08/20/2008CN101244269A Recombined foot and mouth disease virus amalgamation protein vaccine
08/20/2008CN101244268A Eimeria Tenella complex immunity regulation type DNA vaccine
08/20/2008CN100412196C Protection against environmental toxicity through manipulation of processing of messenger RNA precursors
08/20/2008CN100412193C Anti human CD19 mouse immune globulin variable zone gene and uses
08/20/2008CN100412090C Novel tissue factor targeted thrombomodulin fusion proteins as anticoagulants
08/20/2008CN100411689C Use of ShRNA for suppressing telomere enzyme reverse transcriptase hTERT expression in antineoplastic action
08/19/2008US7415302 Method and system for leading macromolecule substances into living target cells
08/19/2008US7414122 host cell, viral vector; agonists and antagonists; diagnosis or treatment of cancer; antiproliferative; infertility, miscarriage, preterm labor and delivery, and endometriosis; immunosuppressants; vaccine adjuvants; genetic mapping
08/19/2008US7414120 enhances ubiquitination of phosphorylated I kappa B; human E3 ubiquitin ligase polypeptides; inflammatory diseases, autoimmune diseases, cancer and viral infections
08/19/2008US7414108 novel prostatic acid phosphatase and corresponding coding region derived from mouse; immunizing a subject with a xenogeneic polypeptide antigen, either alone, as part of a viral antigen construct, or as part of a pulsed dendritic cell preparation.
08/19/2008US7414035 hKIS composition and methods of use
08/19/2008US7414034 Administering antibody polynucleotide; controlling glutamate receptors
08/19/2008US7414027 Peptide antagonists of vascular endothelial growth factor
08/19/2008US7414024 B-cell differentiation factor (il-6); anticancer agents; antisense agents; monoclonal antibody
08/19/2008US7414020 DNA expression vector; host cell transformed, transfected or infected with the vector; transgenic cell, tissue or organism; HCDS1 protein
08/19/2008US7413895 Nucleotide sequences coding cell surface protein associated with amino acid transport for use in identifying modlator for treatment and prevention of cell proliferative disorders; antitumor agents; antiproliferative agents
08/19/2008US7413864 Treating cancer using a telomerase vaccine
08/19/2008US7413860 Testing for disease by analyzing if gene has mutation
08/19/2008US7413853 Modulation of metabolism of steroids and xenobiotics
08/19/2008US7413742 Clostridial toxin derivatives and methods for treating pain
08/19/2008CA2318372C A universal immunomodulatory cytokine-expressing bystander cell line and related compositions and methods of manufacture and use
08/19/2008CA2241172C Episomal vector and uses thereof
08/19/2008CA2151801C 3'-modified oligonucleotide derivatives