Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
02/2009
02/24/2009US7494653 Inoculating a patient with an effective amount of PcrV antigen; monoclonal antibodies specific for the PcrV antigen
02/24/2009US7494646 Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
02/24/2009US7494644 contacting a myocardial cells with genetic engineered mammalian cells modified to express a connexin 43 proteins, to establishing electrical coupling between cardiomyocytes and recombinant cells; treatment of cardiac disease or tissue repair
02/24/2009CA2415364C Diagnostic and therapeutic methods based on the l1 adhesion molecule for ovarian and endometrial tumors
02/24/2009CA2360437C Method of acquiring immunological tolerance
02/24/2009CA2329129C Stable gene formulations comprising saccharides
02/24/2009CA2179029C Vertebrate embryonic pattern-inducing hedgehog-like proteins
02/24/2009CA2174556C Recombinant p53 adenovirus methods and compositions
02/19/2009WO2009023814A2 Hucbc treatment of amyloid associated disease
02/19/2009WO2009023795A2 Cell-based compositions and method for treating conditions of the nervous system
02/19/2009WO2009023525A2 Methods of modulating mesenchymal stem cell differentiation
02/19/2009WO2009023333A2 Inhibition of the sh2-domain containing protein tyr-phosphatase, shp-1, to enhance vaccines
02/19/2009WO2009023055A2 Blockade of the inhibitory qa-1-cd94/nkg2a pathway for treatment of autoimmune disease
02/19/2009WO2009023053A2 Use of rsk inhibitors to impede intracellular pathogen infections
02/19/2009WO2009022174A2 Non-aggregating virus formulation
02/19/2009WO2009021325A1 Microrna compositions and methods for the treatment of myelogenous leukemia
02/19/2009WO2009002832A3 Inhibitors of ncca-atp channels for therapy
02/19/2009WO2009002380A3 Isolation of anti-desmoglein 1 antibodies by phage display of pemphigus foliaceus autoantibodies
02/19/2009WO2008157324A3 Peptide linked cell matrix materials for stem cells and methods of using the same
02/19/2009WO2008156629A3 Methods and agents for inhibiting tumor growth by targeting the ssdna replication intermediate of tumor stem cells
02/19/2009WO2008144365A3 Method for making dry powder compositions containing ds-rna based on supercritical fluid technology
02/19/2009WO2008127285A3 Target peptides for ovarian cancer immunotherapy
02/19/2009WO2006118564A3 MODIFIED CELLS EXPRESSING A PROTEIN THAT MODULATES ACTIVITY OF bHLH PROTEINS, AND USES THEREOF
02/19/2009WO2006112869A3 Modulation of cytokine signaling regulators and applications for immunotherapy
02/19/2009US20090048435 Oligonucleotide modulation of cell adhesion
02/19/2009US20090048201 Use of targeted cross-linked nanoparticles for in vivo gene delivery
02/19/2009US20090048191 Therapeutic molecules for modulating stability of vegf
02/19/2009US20090048148 Compositions and methods for therapeutic use
02/19/2009US20090047735 Antibodies Against Human G-Protein Chemokine Receptor (CCR5) HDGNR10
02/19/2009US20090047733 Avidin-Pseudotyped Viral Vectors and Their Use
02/19/2009US20090047668 Novel method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same
02/19/2009US20090047339 Polynucleotides encoding antigenic HIV type C polypeptides, polypeptides and uses thereof
02/19/2009US20090047275 Modulating calvarial osteoblast differentiation; fracture repair
02/19/2009US20090047259 Methods of Using the Calcineurin A Variant CnA-beta 1
02/19/2009US20090047217 Polynucleotides Encoding Members of the Human B Lymphocyte Activation Antigen B7 Family and Polypeptides Encoded Thereby
02/19/2009CA2733676A1 Microrna compositions and methods for the treatment of myelogenous leukemia
02/19/2009CA2695892A1 Non-aggregating virus formulation
02/18/2009EP2025757A2 Polymeric immunoglobulin receptor-mediated gene transfer
02/18/2009EP2025752A2 Antisense oligonucleotides for the inhibition of expression of type I procollagen
02/18/2009EP2025347A1 Prophylactic and therapeutic agent for cancer
02/18/2009EP2023961A1 Method for isolating homogeneous populations of transduced progenitors stably expressing specific levels of a transgene
02/18/2009EP1636260B1 Improved secretion of neublastin
02/18/2009EP1434884B1 Single nucleotide polymorphisms predicting cardiovascular disease
02/18/2009EP1135467B1 Psca: prostate stem cell antigen and uses thereof
02/18/2009EP1007631B2 Cardiac muscle regeneration using mesenchymal stem cells
02/18/2009EP0673415B1 Recombinant viral vector system
02/18/2009CN101370513A Immunogenicity polypeptide composed of optimized concealed peptide derived from tumor antigen
02/18/2009CN101368187A Recombinant human FUS1 and human IL-12 dual-gene expression carrier, liposome complexes, preparation method and application thereof
02/18/2009CN101368173A Antihuman CD44 monoclone antibody hybridoma cell line, monoclone antibody, engineering antibody, carrier, reagent kit and uses thereof
02/18/2009CN101367869A Polypeptide for preventing, diagnosing and treating hepatitis E virus, and vaccine as diagnosis agent of the same
02/18/2009CN101366950A Uses of gamma-ray combined phTERT-HRP/IAA in medicament for treating cancer of larynx
02/18/2009CN101366949A Method for improving feed efficiency and/or growth rate and/or fat reduction of livestock
02/18/2009CN100462438C Chimeric type 5/type 11 or type 35 adenovirus vector for preventing infection with antihuman immunodeficiency virus
02/18/2009CN100462135C Polyethylenimine derivates nanometer hollow microspheres and the preparing method
02/18/2009CN100462104C Targeting-fusion DNA vaccine for caries-prevention, and its prepn. method
02/17/2009US7491815 Antisense modulation of C-reactive protein expression
02/17/2009US7491550 Diagnostics and therapeutics for diseases associated with Neuromedin U2 receptor (NMU2)
02/17/2009US7491538 Gene expression with covalently modified polynucleotides
02/17/2009US7491537 Nucleic acid formulations for gene delivery and methods of use
02/17/2009US7491525 Specific proliferation in tumour cell which can express antioncogene with high efficiency and the use of it
02/17/2009US7491508 termini grow efficiently in desired cell line; left terminus spans the 5' inverted terminal repeat, left terminus spans the E4 region and the 3' inverted terminal repeat; internal regions does not grow efficiently in the desired cell; adenovirus vectors use for gene therapy; culturing; vaccines
02/17/2009US7491401 Lawsonia intracellularis vaccine
02/17/2009US7491398 Proteins in enteroaggregative Escherichia coli (EAEC) useful for diagnosis and therapy of EAEC infections
02/17/2009US7491389 Bone marrow; controlling cell differentiation
02/17/2009US7491385 Polynucleotide gene expression construction; therapy of diseases caused by damage to excitable tissue; cardiovascular disorders therapy; antidiabetic agents; Parkinson's disease; antiepileptic agents; neurodegenerative agents
02/17/2009CA2301874C Suppression of malignancy utilizing ribonucleotide reductase r1
02/17/2009CA2282812C Adenovirus vectors specific for cells expressing androgen receptor and methods of use thereof
02/17/2009CA2236455C Human p27kip1 gene promoter
02/17/2009CA2233166C Hormone immunomodulated induction of mucosal immune responses
02/12/2009WO2009021235A2 Methods and compositions for treating cancer
02/12/2009WO2009021232A2 High-throughput, whole-animal screening system
02/12/2009WO2009021034A2 Methods of treating b-cell cancers
02/12/2009WO2009020645A2 Matriptase protein and uses thereof
02/12/2009WO2009020550A2 Composites for biomedical applications
02/12/2009WO2009020119A1 Pharmaceutical containing hif-1 alpha and hif-2 alpha expression inhibitor
02/12/2009WO2009020028A1 Determination and suppression of expression level of g protein-coupled receptor kinase 4 gene in breast cancer cell
02/12/2009WO2009019612A2 Lentiviral gene transfer vectors and their medicinal applications
02/12/2009WO2008145400A3 Mutated structural protein of a parvovirus
02/12/2009WO2008131807A3 Splice switching oligomers for tnf superfamily receptors and their use in treatment of disease
02/12/2009WO2008131191A8 Nucleic acids hybridizable to micro rna and precursors thereof
02/12/2009WO2008102274A3 Meganuclease variants cleaving a dna target sequence from the beta-2-microglobulin gene and uses thereof
02/12/2009WO2007096882A3 Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
02/12/2009US20090043383 Genetically modified heart valve xenografts
02/12/2009US20090043085 Methods and compositions for the specific inhibition of gene expression by double-stranded rna
02/12/2009US20090043083 Methods and compositions for the specific inhibition of gene expression by double-stranded rna
02/12/2009US20090043082 Microrna and methods for inhibiting same
02/12/2009US20090042830 Novel oncogene, recombinant protein derived therefrom, and uses thereof
02/12/2009US20090042828 Nucleic acid with 1st sequence encoding antisense RNAi specific for targeting regions of copper zinc superoxide dismutase that cause inherited amyotrophic lateral sclerosis, and a 2nd sequence encoding a RNAi resistant replacement gene with silent mutations encoding messenger RNA resistant to cleavage
02/12/2009US20090042827 Antiviral oligonucleotides targeting hbv
02/12/2009US20090042799 Light chain that cleaves a neurosecretory protein; an HN domain that translocates the light chain across an endosome membrane and a substance P targeting moiety; the HC domain is removed or modified to reduce the targeting of the modified Clostridial toxin to the neuromuscular junction
02/12/2009US20090042797 Gamma-heregulin
02/12/2009US20090042796 Derivatives of the il-2 receptor gamma chain, their production and use
02/12/2009US20090042230 Flea allantoinase proteins and uses thereof
02/12/2009US20090042199 Nucleotide sequences coding lymphocyte adhesion protein for use in treatment of autoimmunity, inflammation and infection
02/12/2009US20090041804 Foreign nucleic acid molecule encoding multiple costimulatory molecules, such as B7-1 or B7-2 (antigens), intercellular adhesion molecules and leukocyte function associated antigen-3
02/12/2009US20090041759 Materials and methods for treating ocular-related disorders
02/12/2009US20090041735 CD34 Stem cell-related methods and compositions
02/12/2009US20090041731 Treatment for Diabetes
02/12/2009US20090041726 Tumor therapy with high affinity laminin receptor-target vectors and combinations with chemotherapeutic agents
02/12/2009US20090041718 Methods of Modulating Cytokine Activity; Related Reagents