Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
05/2009
05/27/2009CN100490903C Oligonucleotide for targeted activation of chronic granulocyte leukaemia protein kinase PKR and application thereof
05/27/2009CN100490902C Photochemical internalization for virus-mediated molecule delivery into the cyosol
05/26/2009US7538258 Transgenic nonhuman animal having germ or somatic cell containing nucleic acid encoding human amyloid precursor protein including nucleotides encoding codon 670 and 671; diagnosing and/or predicting predisposition; drug screening
05/26/2009US7538097 Inhibition of antigen presentation with poorly catabolized polymers
05/26/2009US7538093 Compositions and methods for therapeutic use
05/26/2009US7538091 D-retro-inverso amino acid sequence transporter peptide conjugated to nucleic acid biological effector; translocation across the membrane of pancreatic B-cells
05/26/2009US7538083 Compositions and methods for the potentiation of immune responses against target antigens
05/26/2009US7537929 Nucleotide sequences coding serine protease inhibitor for use in targeting and killing insect cell
05/26/2009US7537924 Modified herpes simplex viral particle for targeting and destroying tumor cells
05/26/2009US7537908 Using concentration of high mobility group 1 (HMG1) protein as evaluative tool in detection of infection and acute respiratory distress syndrome; treating obesity with high mobility group antagonist
05/26/2009US7537899 Defects in periaxin associated with myelinopathies
05/26/2009US7537887 Relates to regulation of activity of NET (ERP/SAP-2) protein and to compounds which modify or regulate NET protein activity; methods of screening for agonists or antagonists of NET in order to identify new pro- or anti-angiogenic compounds
05/26/2009US7537756 Using nestin-positive pancreatic stem cell to generate insulin producing beta cells; tissue engineering and repair; regenerative medicine
05/26/2009CA2562938C Peg-functional nucleic acid conjugate
05/26/2009CA2497857C Novel p-selectin ligand protein
05/26/2009CA2339495C Phospholipids with unsaturated alkyl and acyl chains
05/26/2009CA2091102C Microsomal triglyceride transfer protein
05/22/2009WO2009065141A1 Methods and compositions for reducing skin damage
05/22/2009WO2009065121A1 Increased stability of a dna formulation by including poly-l-glutamate
05/22/2009WO2009064920A2 Compounds and methods for modulating protein expression
05/22/2009WO2009064917A2 Generation of an hla-negative osteogenic precursor cell line
05/22/2009WO2009062313A1 Composition containing granulocyte colony stimulating factor (gcsf) for hair growth
05/22/2009WO2009062309A1 Methods for the regulation of the prostaglandin f synthase (pgfs) activity of akr1b1 and uses thereof
05/22/2009WO2009032308A3 Sam-ii riboswitch and uses thereof
05/22/2009WO2008116111A3 Growth factor mediated cosmeceuticals and use thereof to enhance skin quality
05/22/2009WO2006119266A3 Human micrornas and methods for inhibiting same
05/22/2009WO2006072954A3 Novel il-6 polynucleotides encoding variant il-6 polypeptides and methods using same
05/22/2009CA2705862A1 Compositions and method for manipulating pim-1 activity in circulatory system cells
05/22/2009CA2705376A1 Methods for the regulation of the prostaglandin f synthase (pgfs) activity of akr1b1 and uses thereof
05/21/2009US20090133136 Inducible SIRNA expression cassette and method of use
05/21/2009US20090131946 Devices and Methods for the Restoration of a Spinal Disc
05/21/2009US20090131646 Novel bag proteins and nucleic acid molecules encoding them
05/21/2009US20090131359 Antifibrotic therapy
05/21/2009US20090131353 Using cyclic nucleotide phosphodiesterase profiles as tool in detection of cell proliferative disorders
05/21/2009US20090131350 Hybrid Hepatocyte Growth Factor Gene Having High Expression Efficiency of Two Heterotypes of Hepatocyte Growth Factor
05/21/2009US20090130762 Activation of HCV-specific T cells
05/21/2009US20090130715 Antibodies to CD40
05/21/2009US20090130695 Isolated nucleic acid encoding GEF-H1b polypeptide (Guanine nucleotide exchange factors); diagnosing abnormal cell proliferation and drug screening; measuring phosphorylation by p-21 activated kinase; antitumor agents, anticancer agents
05/21/2009US20090130681 21132, a Human G-protein coupled receptor family member and uses therefor
05/21/2009US20090130674 Circular DNA molecule having a conditional origin of replication, process for their preparation and their use in gene therapy
05/21/2009US20090130078 Treatment for Cardiovascular Disease
05/21/2009US20090130062 Novel Application of Heparin-Binding Epidermal Growth Factor-Like Growth Factor for Medical Purposes
05/21/2009US20090130061 Adenovirus vectors containing cell status-specific response elements and methods of use thereof
05/21/2009US20090130054 Apc activators in combination with a cytokine-secreting cell and methods of use thereof
05/20/2009EP2060634A1 Structure protein of adeno-associated virus with amended antigenity, production and application thereof
05/20/2009EP2060633A1 Mammalian artificial chromosomes
05/20/2009EP2060630A2 PCA3, PCA3 genes, and methods of use
05/20/2009EP2060267A2 Methods for therapy of neurodegenerative disease of the brain
05/20/2009EP2059598A1 Compositions and methods for modulating ampa receptor-mediated excitotoxicity
05/20/2009EP2059263A1 Use of light sensitive genes
05/20/2009EP2059262A1 A dna vaccine for treating or preventing cervical cancer comprising a gene encoding hpv protein
05/20/2009EP1592789B1 Administration of transposon-based vectors to reproductive organs
05/20/2009EP1330265B1 Formulations comprising dextrin polymers in combination with sugars for the delivery of nucleic acids
05/20/2009EP1231910B1 Pentamidine for treating cancer
05/20/2009CN101437834A Modulation of cytokine signaling regulators and applications for immunotherapy
05/20/2009CN101437538A Modified adenovirus hexon protein and uses thereof
05/20/2009CN101437399A Methods and agents for modulating an immune response
05/20/2009CN101434962A Japanese blood fluke (Chinese mainland strain) tyrosine kinase TK4 conserved region gene, and cloning expression method and use thereof
05/20/2009CN101434956A Heavy and light chain variable region gene of monoclonal antibody, encoding polypeptide thereof and use
05/20/2009CN101434657A Preparation and use of recombinant mtVEGF121/MAP30KDEL fusion noxioussubstance
05/20/2009CN101434629A SiRNA sequence inhibiting human Akt2 gene expression and fusion expression vector
05/20/2009CN101433725A Novel magnetic target gene transmission system and preparation thereof
05/20/2009CN101433724A Use of Akt2-siRNA fusion expression vector in preparing medicament for inhibiting metastasis of human breast cancer cell
05/20/2009CN101433722A Fusions of cytokines and tumor targeting proteins
05/20/2009CN101433715A Modified chimeric polypeptides with improved pharmacokinetic properties
05/20/2009CN100489105C Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector
05/20/2009CN100489091C Recombinant herpes simplex virus capable of excreting angiostatin and endostatin protein and its application in treating lung cancer
05/20/2009CN100488981C Proaerolysin containing protease activation sequences and its uses
05/20/2009CN100488568C Cell preparation capable of excreting chalone of endothelium, and application for preparing medicine for treating tumor
05/20/2009CN100488567C Cancer gene therapeutic drug
05/19/2009US7534915 Non-symmetrical gelling agent
05/19/2009US7534879 2'-O-methyl-phosphorothioate oligoribonucleotide modification; peptide nucleic acids, locked nucleic acids, and/or morpholino phosphorodiamidate oligonucleotides; splicing
05/19/2009US7534878 Composition and methods of RNAi therapeutics for treatment of cancer and other neovascularization diseases
05/19/2009US7534874 Gene involved in V(D)J recombination and/or DNA repair
05/19/2009US7534775 Methods and compositions for modulating cardiac contractility
05/19/2009US7534774 Contacting a wound site with formulation comprising nucleic acid molecule and a biocompatible matrix, the wound site being situated in a tissue associated with the fluid space
05/19/2009US7534773 reduces the expression of testosterone-repressed prostate message-2 provides therapeutic benefits in the treatment of cancer for example prostate cancer and renal cell cancer; Combined use with taxanes synergistically enhances cytotoxic chemosensitivity of androgen-independent prostate cancer
05/19/2009US7534772 Methods for enhancing antibody-induced cell lysis and treating cancer
05/19/2009US7534769 Cholic acid or deoxycholic acid derivatives can include polypeptides, polynucleotides such as genes and antisense nucleic acids that can modulate cellular activity
05/19/2009US7534613 Methods of treating parkinson's disease using viral vectors
05/19/2009US7534565 Using decreased expression of deleted in liver cancer 1(DLC-1) as diagnostic indicator of cell proliferative disorders in breast, collon and liver
05/19/2009US7534564 Methods and compositions for polypeptide engineering
05/19/2009US7534559 Feline polynucleotide vaccine formula
05/19/2009US7534445 isolated nucleotide sequences and degenerate sequences encoding the high molecular weight HMW protein; vaccines; antibodies; vectors
05/19/2009US7534440 Fusion molecules and methods for treatment of immune diseases
05/19/2009US7534439 Nucleic sequence and deduced protein sequence family with human endogenous retroviral motifs, and their uses
05/19/2009US7534425 As well as Paget's disease, neurological/neuromuscular diseases, nerve diseases, and/or psychotropic diseases; chloride channel modulators
05/19/2009US7534424 Optimizing the dosage of a therapeutic nucleic acid by using doxorubicin which is known to deplete liver macrophages known as Kupffer cells, thereby reducing liver toxicity
05/19/2009CA2387247C Use of neutralizing agents to growth factors for reducing wound scarring
05/19/2009CA2367955C Abc1 polypeptide and methods and reagents for modulating cholesterol levels
05/19/2009CA2247071C Dna vaccination for induction of suppressive t cell response
05/14/2009WO2009062169A2 Micro-rnas of the mir-15 family modulate cardiomyocyte survival and cardiac repair
05/14/2009WO2009062149A1 Methods for maintaining inner ear neurons
05/14/2009WO2009062128A2 Combination drug therapy for the treatment of cancer
05/14/2009WO2009062104A2 Aberrant expression of zinc transporter zip4 (slc39a4) significantly contributes to human pancreatic cancer pathogenesis and progression
05/14/2009WO2009061130A2 Cell permeable runx3 recombinant proteins, polynucleotides encoding the same, and anticancer compositions including the same
05/14/2009WO2009061003A2 Nucleic acid complex and nucleic acid delivery composition
05/14/2009WO2009060982A1 Cancer cell death inducer having activity of potentiating anti-cancer agent in cancer having resistance against the anti-cancer agent
05/14/2009WO2009060124A2 Use of oligonucleotides with modified bases in hybridization of nucleic acids
05/14/2009WO2009059425A1 Stat3 inhibitors for the treatment of fibrosis