Patents
Sitemap › A61 - Medical or veterinary science; Hygiene › A61K - Preparations for medical, dental, or toilet purposes › A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
04/2010
04/21/2010CN101696413A SiRNA-935 capable of inhibiting BCLL11B expression and tumorous T cell proliferation and use thereof
04/21/2010CN101696412A SiRNA-434 capable of inhibiting BCL11B expression and tumorous T cell proliferation and use thereof
04/20/2010US7700760 RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA)
04/20/2010US7700758 Preparing library of heterogenous small interfering RNA sequences (HSIRNA) for use in gene expression inhibition and mammalian therapeutics; gene therapy
04/20/2010US7700757 for treatment of chronic inflammatory bowel disease, Crohn's disease and ulcerative colitis
04/20/2010US7700755 cytotoxins; host cells; vaccines; histology
04/20/2010US7700749 Nucleic acid and corresponding protein entitled 205P1B5 useful in treatment and detection of cancer
04/20/2010US7700742 Antibodies to insulin-like growth factor I receptor
04/20/2010US7700724 Mixture comprising serum complement system protein (INSP163) use in preparation of vaccines and antibodies for treatment and prevention of infection, cell proliferative, skin, neurodegenerative, bone, inflammatory, respiratory system and autoimmune disorders
04/20/2010US7700574 Receptor activator of NF-kappaB ligand (RANKL); antisense agents; drug screening; kits
04/20/2010US7700572 SMAD7 inhibitors for the treatment of CNS diseases
04/20/2010US7700571 Compositions and methods for liver growth and liver protection
04/20/2010US7700570 Oligonucleotide mediated specific cytokine induction and prophylaxis and treatment of viral infection in a mammal
04/20/2010US7700562 Use of —furin—“convertase” inhibitors in the treatment of fibrosis and scarring
04/20/2010US7700558 Methods for treating diabetes using fibroblast growth factor-like polypeptides
04/20/2010US7700362 Method for screening therapeutic agents for disuse muscular atrophy using interaction between selected proteins and a polyubiquitin chain
04/20/2010US7700351 Methods and compositions for tissue regeneration
04/20/2010US7700350 for the production of reconstituted HCMV virus retaining phenotypic characteristics of a clinical virus isolate including the ability to grow on endothelial cells and to induce microfusion
04/20/2010US7700341 Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
04/20/2010US7700316 CD109 nucleic acid molecules, polypeptides and methods of use
04/20/2010US7700280 Methods for assessing cisplatin resistance, disease progression, and treatment efficacy in ovarian cancer
04/20/2010US7700274 Compositions and methods in cancer associated with altered expression of KCNJ9
04/20/2010US7700272 Ligand gated chloride channel for use as screening tool in identifying/screening pesticidal and antiparasitic agents
04/20/2010US7700119 85kDa neisserial antigen
04/20/2010US7700114 original codons are exchanged by codons which lead to an enhanced translation in a mammalian cell, contain a deletion resulting in the production of a truncated non-functional protein; capable of enhancing the immunogenicity
04/20/2010US7700104 Attenuated Salmonella SP12 mutants as antigen carriers
04/20/2010US7700092 Pneumovirus NS proteins antagonize the interferon IFN response
04/20/2010US7700091 Bacterium for use as vehicle for gene transport and transfer to preferential organs or tissues; tissue engineering and targeted somatic transgenesis
04/20/2010US7700088 Interleukin-9 mutein peptides
04/20/2010US7699832 Medical device having a surface including a biologically active agent therein, and methods
04/20/2010CA2515366C Compositions and methods to modulate immune and inflammatory responses
04/20/2010CA2400172C Nanocapsule encapsulation system and method
04/20/2010CA2299429C New lipopolyamines,their preparation and the use thereof
04/20/2010CA2287541C Regulatory system for inducible expression of genes with lambdoid promoters
04/20/2010CA2180872C Composition containing nucleic acids, preparation and uses
04/15/2010WO2010042868A2 Methods for treating obesity
04/15/2010WO2010042755A2 Chimeric therapeutics, compositions, and methods for using same
04/15/2010WO2010042751A2 Chimeric therapeutics, compositions, and methods for using same
04/15/2010WO2010042749A2 Chimeric therapeutics, compositions, and methods for using same
04/15/2010WO2010042636A2 Telomerase inhibitors and methods of use thereof
04/15/2010WO2010042530A2 Nlrc5 as a target for immune therapy
04/15/2010WO2010042281A2 Antisense oligonucleotides directed against connective tissue growth factor and uses thereof
04/15/2010WO2010041716A1 Promoter for regeneration of tendon-bone junction tissue or ligament-bone junction tissue
04/15/2010WO2010040901A1 Alternative oxidase and uses thereof
04/15/2010WO2010040173A1 A method of delivering functional agents across the blood-brain barrier
04/15/2010WO2010022198A3 Rcc t cell receptors and related materials and methods of use
04/15/2010WO2009080299A8 Sm-protein based secretion engineering
04/15/2010US20100095398 Protection against environmental toxicity through manipulation of the processing of messenger RNA precursors
04/15/2010US20100093987 Inhibitor Nucleic Acids
04/15/2010US20100093840 Human Sef isoforms and methods of using same for cancer diagnosis and gene therapy
04/15/2010US20100093839 hypoxia-inducible factor-1 alpha (HIP-1 alpha); nucleosides, Locked Nucleic Acids; treating kidney cancer, melanoma, glioblastoma and prostate cancer, and pre-eclampsia
04/15/2010US20100093838 Regulation of angiogenesis with zinc finger proteins
04/15/2010US20100093837 Microrna molecules
04/15/2010US20100093834 Manipulation of neuronal ion channels
04/15/2010US20100093831 Nucleic acid compounds for inhibiting angiogenesis and tumor growth
04/15/2010US20100093058 High Transgene Expression Of A Pseudotyped Adeno-Associated Virus Type
04/15/2010US20100092572 Chitosan-based colloidal particles for rna delivery
04/15/2010US20100092540 Drug delivery compositions and medical devices containing block copolymer
04/15/2010US20100092502 Modified hiv env polypeptides
04/15/2010US20100092463 Method for treating or preventing osteoporosis by reducing follicle stimulating hormone to cyclic physiological levels in a mammalian subject
04/15/2010US20100092424 Method of diagnosis and treatment of tumors using high intensity focused ultrasound
04/15/2010DE102008050860A1 LCMV-GP-VSV-Pseudotypvektoren und tumorinfiltrierende Virenproduzentenzellen zur Therapie von Tumoren LCMV-GP-VSV pseudotype vectors and tumor-infiltrating virus producer cells for the therapy of tumors
04/15/2010CA2739788A1 Telomerase inhibitors that bind to the cr4-cr5 domain of the rna component of human telomerase and methods of use thereof
04/14/2010EP2174955A1 Ifnar2 muteins, their production and use
04/14/2010EP2174945A1 Antisense modulation of apolipoprotein B expression
04/14/2010EP2174668A2 Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
04/14/2010EP2173908A2 Ultraconserved regions encoding ncrnas
04/14/2010EP1399483B1 Antibodies to insulin-like growth factor i receptor
04/14/2010EP1294922B1 Treating cancer using organelle crystallizing agents
04/14/2010EP1294866B1 Use of acrp30 globular head to promote increases in muscle mass and muscle differentiation
04/14/2010EP1237918B1 A gene, disrupted in schizophrenia
04/14/2010EP1207199B1 Tumor antigen
04/14/2010EP0831903B1 Connective tissue growth factor
04/14/2010CN1852690B Medicament conveying system
04/14/2010CN1643147B Methods and means for monitoring and modulating gene silencing
04/14/2010CN101693890A Immunostimulatory sequence oligonucleotides and methods of using the same
04/14/2010CN101693736A Novel peptides
04/14/2010CN101693107A Methods of treating neurological conditions with hematopoeitic growth factors
04/14/2010CN101280317B FAK and EGFR targeted RNA interference plasmid-lipidosome antineoplastic complex
04/14/2010CN101092631B Modified ORF2 gene of toroidal virus of pig, and application
04/13/2010US7696345 Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation
04/13/2010US7696344 Short interference RNA duplexes, when introduced into mammalian cells in culture, perform sequence-specific inhibition of target mRNA without inducing an interferon response; specific gene silencing
04/13/2010US7696332 Replication vector showing cell-specific expression
04/13/2010US7696331 parenterally administering a dose of samarium ethylenediaminetetramethylenephosphonic acid (EDTMP); and carboplatin or taxoids; anticarcinogenic, antitumor, and antantiproliferative agents; autoimmune, infectious , metabolic or genetic disorders
04/13/2010US7696180 Antisense oligonucleotide derivative as antitumor agent; biodrugs
04/13/2010US7696179 inhibiting HIV entry into CCR5-expressing cells; treatment and prevention of infectious diseases or disorders, e.g., HIV infection, AIDS, and AIDS-related diseases
04/13/2010US7696172 culture product produced by culturing a recombinant host cell under suitable conditions to express the polypeptide; has an oncogenic activity; treating liver disorder cirrhosis, or pancreas disorder
04/13/2010US7696154 Administering formulation comprising polypeptide and muteins, fused proteins, muteins, functional derivatives and active fragments for treating autoimmune diseases, Type I diabetes, rheumatoid arthritis, graft rejections, inflammatory bowel disease, sepsis, multiple sclerosis, ischemic heart disease etc.
04/13/2010US7696151 Providing a screening assay having stearoyl-CoA desaturase biological activity, contacting sceening assay with a test compound and measuring the biological activity
04/13/2010US7695961 Insulin related transcription factor and uses thereof
04/13/2010US7695960 vaccination directed against the hepatitis C virus (HCV);
04/13/2010US7695959 Delivering an adeno-associated virus vector comprising a nucleotide sequence encoding glutamic acid decarboxylase to cells in specific areas of the brain; Parkinson's Disease, Alzheimer's Disease, Amyloid Lateral Sclerosis, and epilepsy
04/13/2010US7695934 Pure polypeptide containing a fragment capable of binding to and inducing apoptosis in a carcinoma cell; Tumor Necrosis Factor Related ligand "TRELL; gene therapy to treat tumors, autoimmune and inflammatory diseases or inherited genetic disorders
04/13/2010US7695902 Contacting test solution containing Rna and enzyme; hybridization
04/13/2010CA2472280C Cytotoxic cyplasin of the sea hare, aplysia punctata, cdna cloning and expression of bioreactive recombinants
04/13/2010CA2431308C Regulation of angiogenesis with zinc finger proteins
04/13/2010CA2383372C Cell-specific and/or tumor-specific promoter retargeting of herpes gamma 34.5 gene expression
04/13/2010CA2330206C Poly(adp-ribose) polymerase gene
04/13/2010CA2314397C Novel peptide, apoep1.b, compositions and uses thereof
04/13/2010CA2290664C Compounds, preparation and use for transferring nucleic acids into cells
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