Patents
Sitemap › A61 - Medical or veterinary science; Hygiene › A61K - Preparations for medical, dental, or toilet purposes › A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
06/2010
06/16/2010CN101732731A Lentiviral vector-mediated gene transfer and uses thereof
06/16/2010CN101732730A Cation lipid containing imidazolium salt and macrocyclic polyamines, transgenetic vector and method for preparing same
06/16/2010CN101732729A RNA interference medicine capable of reversing multi-medicine drug resistance of leukaemia
06/16/2010CN101732723A Polyethylene glycol-poly(lactic-co-glycolic acid)-polylysine nano-delivery system, preparation method and application thereof
06/16/2010CN101732717A Ttk in diagnosis and as a therapeutic target in cancer
06/16/2010CN101732714A Manchette binding protein and effects thereof during spermiogenesis
06/15/2010US7737267 Short interference RNA duplexes when introduced into mammalian cells in culture perform sequence-specific inhibition of target mRNA without inducing an interferon response; for gene silencing to treat human diseases; double stranded siRNA
06/15/2010US7737266 double-stranded ribonucleic acid for inhibiting the expression of sterol regulatory element binding proteins (SREPB) cleavage activating protein (SCAP) genes in cells
06/15/2010US7737264 Oligomeric compounds for the modulation HIF-1α expression
06/15/2010US7737125 oligonucleotide compounds (oligomers), which target androgen receptor mRNA in a cell, leading to reduced expression of the androgen receptor; reduction of androgen receptor expression is beneficial for treatment of certain disorders, such as hyperproliferative disorders (e.g., cancer)
06/15/2010US7737124 transfecting a packaging cell line with a retroviral construct, then recovering a recombinant retrovirus from the packaging cell line and infecting a target cell ex vivo with the recombinant retrovirus; downregulating chemokine receptors (CCR5); treatment of viral diseases
06/15/2010US7737116 Modified and stabilized GDF propeptides and uses thereof
06/15/2010US7736899 Cells and method for producing proteins comprising an unconventional amino acid
06/15/2010US7736898 a eukaryotic expression vector comprising a recombinant nucleotide sequence encoding hydrolase enzymes, used to induce apoptosis in vertebrate cells in vivo by reducing the level of thiamine in the cells; inducing apoptosis in cancer cells
06/15/2010US7736896 culturing a multilayer of human embryonic stem cells, for a sufficient time to allow for the appearance of putative cells comprising brown pigment dispersed within their cytoplasm, culturing the putative cells to form a cell monolayer containing cells that are Pax6 negative and bestrophin positive
06/15/2010US7736895 Altering differentiated state of somatic cells via adjusting gene expression patterns; removing suppressor protein from chromatin masses; reprogramming differentiated cells
06/15/2010US7736892 development of a bank of stem cells that can be tissue typed and banked and expanded as needed; can be differentiated or genetically manipulated in vitro
06/15/2010US7736873 An isolated nucleic acid molecule comprising a nucleotide sequence which encodes the polypeptide comprising the outer membrane protein antigens of gramnegative bacteria, which can be used to prevent and treat gramnegative bacteria infection in mammals, such as humans; immunology; vaccines
06/15/2010US7736870 Nucleic acid sequences having gene transcription regulatory qualities
06/15/2010US7736869 nucleotide or DNA constructs comprising expression cassettes comprising promoters operably linked to transgene open reading frames, used in protein production, diagnostics, transgenic plants and animals and the therapeutic field
06/15/2010US7736868 Nucleic acid sequences having gene transcription regulatory qualities
06/15/2010US7736659 Clostridial toxin derivatives and methods for treating pain
06/15/2010US7736655 Neuroprotectants; angoigenesis inhibitors; transcription factors; host cells
06/15/2010US7736654 Proteins, polynucleotides, antibodies, transgenic animals, hybridoma; humoral or cellular immune response; pancreatic
06/15/2010US7736646 Methods for modulating angiogenesis with apelin compositions
06/15/2010US7736640 administering to mammal more than one dose of a composition comprising live Newcastle Disease Virus in an amount sufficient to cause tumor regression
06/15/2010CA2410253C Regulating lipid levels via the zmax1 or hbm gene
06/15/2010CA2250000C Methods of modulating melanin synthesis
06/10/2010WO2010065792A2 Treatment of erythropoietin (epo) related diseases by inhibition of natural antisense transcript to epo
06/10/2010WO2010065660A2 Biodegradable polydisulfide amines for gene delivery
06/10/2010WO2010065630A2 Compositions and methods for treating hepatic neoplasia
06/10/2010WO2010065159A1 Inhibition of dna polymerases to augment chemotherapeutic and antimicrobial agents
06/10/2010WO2010065085A2 Methods and compositions for treating or preventing pruritis
06/10/2010WO2010064851A2 Mtor-targeted sirna having an interspecific cross reaction, recombination vector containing same, and pharmaceutical composition containing same
06/10/2010WO2010064736A1 Therapeutic agent for cancer
06/10/2010WO2010064425A1 Method for inhibiting proliferation of cells
06/10/2010WO2010030963A9 Modulation of bcl11a for treatment of hemoglobinopathies
06/10/2010WO2010022143A3 Assessing and treating breast cancer patients
06/10/2010WO2010011281A3 Methods and compositions for the diagnosis and treatment of cancer
06/10/2010WO2009154790A3 Novel metastasis suppressor genes and uses thereof
06/10/2010US20100146648 Immunosuppression by blocking T cell co-stimulation signal 2 (B7/CD28 interaction)
06/10/2010US20100145030 Gene encoding a multidrug resistance human p-glycoprotein homologue on chromosome 7p15-21 and uses thereof
06/10/2010US20100144850 Methods for Differentiating Pancreatic Cancer from Normal Pancreatic Function and/or Chronic Pancreatitis
06/10/2010US20100144841 Control of nk cell function and survival by modulation of ship activity
06/10/2010US20100144837 Diagnosis and treatment of malignant neoplasms
06/10/2010US20100144834 Methods for treating hypercholesterolemia
06/10/2010US20100144637 Nucleic acid and corresponding protein entitled 161p5c5 useful in treatment and detection of cancer
06/10/2010US20100144026 siRNA-mediated gene silencing with viral vectors
06/10/2010US20100144012 A single chain homing endonuclease, comprising a first variant of I-CreI having the amino acid sequence of accession number pdb 1g9y; for genome engineering and gene therapy
06/10/2010US20100143458 Glutamic acid decarboxylase (gad) based delivery system
06/10/2010US20100143415 Streptococcus Pneumoniae Antigens
06/10/2010US20100143360 Human vascular endothelial growth factor 2
06/10/2010US20100143328 Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides
06/10/2010US20100143314 In Vivo Production and Delivery of Erythropoietin or Insulinotropin for Gene Therapy
06/10/2010US20100143309 Viral vectors
06/10/2010US20100143308 Akt nucleic acids, polypeptides, and uses thereof
06/10/2010US20100143304 Adenoviral vector comprising herpes simplex virus type 1 thymidine kinase and a transgene for increasing the expression of the transgene
06/10/2010CA2745329A1 Treatment of erythropoietin (epo) related diseases by inhibition of natural antisense transcript to epo
06/09/2010EP2194137A2 Cells comprising codon optimized retroviral particles
06/09/2010EP2194067A2 Antibodies to insulin-like growth factor I receptor (IGF-IR)
06/09/2010EP2193805A1 Immunosuppression weaning agent comprising tumor cell and antitumor agent using the same
06/09/2010EP2193804A2 Recombinant adenylate cyclase toxin of bordetella induces T cell responses against tumoral antigens
06/09/2010EP2193204A2 Novel lipophilic compositions and uses thereof
06/09/2010EP2193200A1 Nucleic acid codifying for a utrophin transcription specific regulating protein, protein codified thereby and uses thereof
06/09/2010EP2192925A1 Targeting rna with external guide sequences
06/09/2010EP2192919A1 Methods of inhibiting tumor growth using beta 5 integrin antagonists
06/09/2010EP1385864B1 Anti-VEGF-2 antibodies
06/09/2010EP1335981B1 18480 human protein kinase molecules and uses therefor
06/09/2010EP1326988B1 High efficiency retroviral vector which contains genetically engineered cellular non-coding sequence harboring splicing acceptor
06/09/2010EP1062226B1 High affinity nucleic acid ligands of the complement system c5 protein
06/09/2010CN1982324B Oncogene, recombinant protein derived therefrom, and uses thereof
06/09/2010CN1981043B Recombinant lentiviral vector for expression of a flaviviridae protein and applications thereof as a vaccine
06/09/2010CN101724653A Medicament containing natriuretic peptide gene as well as preparation method and application thereof
06/09/2010CN101724651A Dual-host recombination rhabdovirus expression vector and construction method and application thereof
06/09/2010CN101724612A Human epididymis expression sperm binding protein HEL-128 as well as coding gene and application thereof
06/09/2010CN101724606A Porcine circoviruses, vaccines and diagnostic reagents
06/09/2010CN101724590A Arthrobacter HW08 for degrading swainsonine and application thereof
06/09/2010CN101724067A Human epididymis expression sperm binding protein HEL-122 as well as coding gene and application thereof
06/09/2010CN101724065A Human epididymal expression sperm binding protein HEL-202 as well as encoding gene and application thereof
06/09/2010CN101724064A Human epididymis expression sperm binding protein HEL-192 and encoding gene and application thereof
06/09/2010CN101724063A Human epididymis expression sperm binding protein HEL-178 and encoding gene and application thereof
06/09/2010CN101724062A Human epididymis expression sperm binding protein HEL-172 as well as encoding gene and application thereof
06/09/2010CN101724061A Human epididymis expression sperm binding protein HEL-81, encoding gene and application thereof
06/09/2010CN101724060A Human epididymis expression sperm binding protein HEL-90, encoding gene and application thereof
06/09/2010CN101724059A Human epididymis expression sperm binding protein HEL-72, encoding gene and application thereof
06/09/2010CN101724058A Human epididymis expression sperm binding protein HEL-48, encoding gene and application thereof
06/09/2010CN101724055A Human epididymal expression sperm binding protein HEL-215 as well as encoding gene and application thereof
06/09/2010CN101724054A Human epididymal expression sperm binding protein HEL-213 as well as encoding gene and application thereof
06/09/2010CN101724053A Human epididymis expression sperm binding protein HEL-78, encoding gene and application thereof
06/09/2010CN101724052A Human epididymis expression sperm binding protein HEL-65, encoding gene and application thereof
06/09/2010CN101724051A Human epididymis expression sperm binding protein HEL-59, encoding gene and application thereof
06/09/2010CN101724050A Human epididymal expression sperm binding protein HEL-214 as well as encoding gene and application thereof
06/09/2010CN101724049A Human epididymal expression sperm binding protein HEL-207 as well as encoding gene and application thereof
06/09/2010CN101724048A Human epididymal expression sperm binding protein HEL-200 as well as encoding gene and application thereof
06/09/2010CN101724047A Human epididymis expression sperm binding protein HEL-190 and encoding gene and application thereof
06/09/2010CN101724046A Human epididymis expression sperm binding protein HEL-18 and encoding gene and application thereof
06/09/2010CN101724045A Human epididymis expression sperm binding protein HEL-169 as well as encoding gene and application thereof
06/09/2010CN101724044A Human epididymis expression sperm binding protein HEL-97, encoding gene and application thereof
06/09/2010CN101724043A Human epididymis expression sperm binding protein HEL-89, encoding gene and application thereof
06/09/2010CN101724042A Human epididymis expression sperm binding protein HEL-61, encoding gene and application thereof
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