Patents for C40B 30 - Methods of screening libraries (11,320)
10/2003
10/02/2003US20030186250 Using chip comprised of immobilized nucleotide sequences to determine amount of biological molecule in two or more samples; bioassay; competetive binding assay; disease and cancer diagnosis
10/02/2003CA2478981A1 Identification of kinase inhibitors
10/01/2003EP1348961A1 Protein chips, method producing it and detection system of the protein chips, and operating method of the detection system
10/01/2003EP1348767A2 Polymer chip and method for identifying an ionic polymer
10/01/2003EP1348766A1 Method and kit for detecting membrane protein-protein interactions
10/01/2003EP1348035A2 Method for base sequencing and biologically active nucleic acids
10/01/2003EP1348034A2 Oligonucleotide identifiers
09/2003
09/30/2003US6627571 Creation of an array of materials at known locations on a substrate surface, for screening for useful heterogeneous catalytic properties
09/30/2003US6627453 Using frontal chromatography in combination with mass spectrometry to screen a library of compounds to identify and rank those members that bind to a target receptor
09/30/2003US6627445 Containing catalysts in an array of parallel reactors with each reactor containing a catalyst bed, each bed is then simultaneously contacted, at reaction conditions, with a reactant to form an effluent of each reactor; combinatorial
09/25/2003WO2003079024A1 Filament-recruiting fluorescent proteins for the analysis and identification of protein-protein-interactions
09/25/2003WO2003079014A1 Tethered activity-based probes and uses thereof
09/25/2003WO2003078053A1 Process for evaporation and process vessel with integral evaporator
09/25/2003WO2003078051A2 Process for evaporation in an array and an array of process vessels with integral evaporator
09/25/2003WO2003046153A3 The use of quantitative evolutionary trace analysis to determine functional residues
09/25/2003WO2002093297A3 Methods for high-throughput screening and computer modelling of pharmaceutical compounds
09/25/2003US20030180718 Target specific screening and its use for identifying target binders
09/25/2003CA2478167A1 Process for evaporation and process vessel with integral evaporator
09/24/2003EP1346230A2 Screening method based on tsap6 binding partners
09/24/2003EP0655135B1 Random generation and bio-specific selection of chemical compounds
09/23/2003US6623970 Process for testing catalysts using spectroscopy
09/23/2003US6623969 Process for testing catalysts using mass spectroscopy
09/23/2003US6623968 Parallel flow reactor and apparatus for testing catalysts
09/23/2003US6623967 Process for testing catalysts using chromatography
09/18/2003WO2003076943A1 Encoded self-assembling chemical libraries (esachel)
09/18/2003WO2003076932A2 Novel method for detecting and analyzing protein interactions in vivo
09/18/2003WO2003076926A1 Methods for identifying a molecule that may bind to a target molecule
09/18/2003WO2003076901A2 Methods of identifying target polypeptides
09/18/2003WO2003076065A1 Guiding structure reactor
09/18/2003WO2003062468A3 Method for binding site identification using a multi-scale approach
09/18/2003WO2002099382A3 Multiplexing method
09/18/2003WO2002088744A3 Diagnosis of physiological conditions by proteomic characterization
09/18/2003US20030176670 Multivalent macrolide antibiotics
09/18/2003US20030175986 Using fluorescent compound to analysis protein complexes; determination of genome sequence
09/18/2003US20030175799 Comprises stable amino acid sequence scaffold which mimics native protein structures and interactions; drug screening and design
09/18/2003US20030175760 Identifying immunotoxin for treatment of cancers; antitumor/antiproliferative/anticarcinogenic agents
09/18/2003US20030175720 Cluster analysis of genetic microarray images
09/18/2003US20030175173 Catalytic reactor with integral evaporator
09/18/2003US20030173205 Process vessel with integral evaporator
09/17/2003EP1344176A1 Method for analytical jacobian computation in molecular modeling
09/17/2003EP1344065A2 Differential phage capture proteomics
09/17/2003EP1266035A4 Improved methods for generating catalytic proteins
09/16/2003US6621075 Device for delivery of multiple liquid sample streams to a mass spectrometer
09/12/2003WO2002004956A3 Method of identifying conformation-sensitive binding peptides and uses thereof
09/12/2003WO2001096597A3 High throughput screening of compounds for biological activity
09/12/2003WO2001046693A3 Screening under isothermal denaturing conditions
09/11/2003US20030170738 Compounds that modulate processes associated with IgE production and methods and kits for identifying and using the same
09/11/2003US20030170724 Methods of identifying target polypeptides
09/11/2003US20030169638 Removable vessels are placed in a parallel reactor, and reaction components are delivered to each vessel; impeller is rotated in each vessel to mix the components
09/11/2003US20030168349 Device and method for electrochemically generating one or more gases
09/10/2003EP1341606A2 Process for producing a multiplicity of building blocks of a library of materials
09/10/2003EP1341598A2 Process for applying material layers to shaped bodies
09/04/2003WO2003072801A2 Compositions and method for regulation of calcium-dependent signalling in brain
09/04/2003WO2003072752A2 Improved substrate chemistry for protein immobilization on a rigid support
09/04/2003WO2003072747A2 COMPARATIVE MOLECULAR FIELD ANALYSIS (CoMFA) UTILIZING TOPOMERIC ALIGNMENT OF MOLECULAR FRAGMENTS
09/04/2003WO2003072600A2 Methods of screening molecular libraries for active molecules that restore the function of target proteins and peptides that restore the function of mutant p53
09/04/2003WO2002097398A3 Closed substrate platforms suitable for analysis of biomolecules
09/04/2003WO2002095054A3 Method of determining protein interaction inhibitors
09/04/2003US20030167136 Methods for identifying a molecule that may bind to a target molecule
09/04/2003US20030165873 For isolating ligand binding polypeptides; fusion proteins; drug screening; kits; surface plasmon resonance
09/04/2003CA2477459A1 Comparative field analysis (comfa) utilizing topomeric alignment of molecular fragments
09/04/2003CA2477253A1 Compositions and method for regulation of calcium-dependent signalling in brain
09/02/2003US6613575 Frontal chromatography, in combination with mass spectrometry, to identify and rank the compounds that bind to a target receptor
08/2003
08/28/2003WO2003070982A1 Complex comprising at least two biospecific elements separated by a nucleic acid linker e.g. for identification of drug delivery candidates. combinatorial library of such complexes
08/28/2003WO2002097051A3 Protein arrays and methods and systems for producing the same
08/28/2003WO2001097098A3 Computational molecular docking methods for assessing complementarity of combinatorial libraries to biotargets
08/28/2003WO2001081924A3 Reusable microarrays for quantifying low abundance proteins
08/28/2003US20030162942 Binding to ligand; adjustment of pH; elution
08/28/2003US20030162226 High speed screening; resolution of enantiomorphs by crystallization; bioavailability
08/28/2003US20030162221 Complexing, immunoprecipitation, analyzing
08/27/2003EP1337958A2 Method for self-validation of molecular modeling
08/27/2003EP1337957A2 Method for large timesteps in molecular modeling
08/27/2003EP1337853A2 An extended tethering approach for rapid identification of ligands
08/27/2003EP1337826A2 Open substrate platforms suitable for analysis of biomolecules
08/27/2003EP1110086A4 Production of motif-specific and context-independent antibodies using peptide libraries as antigens
08/26/2003US6610472 Assembly and screening of highly complex and fully human antibody repertoire in yeast
08/21/2003US20030157561 Combinatorial libraries of monomer domains
08/21/2003US20030157540 Methods for isolating and characterizing short-lived proteins and arrays derived therefrom
08/21/2003US20030157491 HarA polypeptides and nucleic acids, and related methods and uses thereof
08/20/2003EP1336848A1 Highly efficient method of screening antibody
08/20/2003EP1244515B1 Production of material libraries using sputter methods
08/19/2003US6607921 Methods for screening compound libraries
08/14/2003WO2003067219A2 STRUCTURE OF INTEGRIN αV-β3 EXTRACELLULAR DOMAIN COMPLEXED WITH LIGAND
08/14/2003WO2003067218A2 Real time detection of intermolecular interaction
08/14/2003WO2003066218A1 Device for analyzing a molecule using a fluid contacted with a support bearing a molecule
08/14/2003WO2003033499A3 Inhibitors of cyclin-dependent kinases, compositions and uses related thereto
08/14/2003WO2002048193A3 Camelidae antibody arrays
08/14/2003WO2001079849A3 Protein expression system arrays and use in biological screening
08/14/2003US20030153523 Screening library of test compounds, each of which is attached to a solid support, with a dye-labeled RNA molecule to form a dye-labeled target RNA:support-attached test compound complex
08/14/2003US20030153095 Mixture experiment design method and system
08/14/2003US20030153013 Antibody-based protein array system
08/14/2003US20030153008 Real time detection of intermolecular interaction
08/14/2003US20030152927 Microfluidic microscope slides for immobilization of polypeptides and nucleic acids; drug screening
08/12/2003US6605470 Staining; infrared thermography, spectroscopy, chemiluminescence, chromatography, robotics
08/12/2003US6605449 Saturation mutagenesis to produce progenitor polynucleotide library
08/12/2003CA2348132C A system for cell-based screening
08/07/2003WO2003064043A1 High pressure chemistry reactor
08/07/2003WO2003018797A3 Method and device for integrated protein expression, purification and detection
08/07/2003WO2001098524A3 Protein-protein interactions
08/07/2003US20030149163 Efficiency