Patents for C40B 30 - Methods of screening libraries (11,320)
01/2005
01/20/2005US20050014184 Arrays, computer program products and methods for in silico array-based comparative binding arrays
01/19/2005EP1497457A1 Method and kit for detecting membrane protein-protein interactions
01/19/2005EP1497455A2 Detection of nucleic acid sequences by cleavage and separation of tag-containing structures
01/19/2005EP1497325A1 Two green fluorescent protein fragments and their use in a method for detecting protein - protein interactions
01/19/2005EP1265700B1 Parallel flow process optimization reactor
01/18/2005US6844165 For diagnosis, drug discovery; both parallel and muliplex analyte processing capabilities; retentate chromatography is a combinatorial method to provide high information resolution of analytes in complex mixtures
01/13/2005WO2005003778A2 A method for identifying a synthetic molecule having affinity towards a target
01/13/2005WO2004077062A3 Method for selecting a candidate drug compound
01/13/2005WO2004068116A3 Receptor deorphanization using tagged molecular libraries
01/13/2005WO2004046164A9 Unique recognition sequences and methods of use thereof in protein analysis
01/13/2005WO2003040994A3 Cyp2c9 binding models
01/13/2005US20050009204 Multiplexed binding assays for receptor arrays
01/13/2005US20050009189 Using transgenic plants comprising enhanced very long chain fatty acid elongases (VLCFAE) as diagnostic tools in detecting modulators of plant growth; herbicides and crop protection
01/13/2005US20050009175 Chemical processing microsystems comprising high-temperature parallel flow microreactors
01/13/2005US20050009110 Identifying and rasing monoclonal antibodies specific to endothelial growth factors for use in the treatment and detection infection, autoimmune and cell proliferative disorders
01/13/2005US20050009093 Focussing of compound libraries using atomic electrotopological values
01/13/2005US20050009081 Optical systems and methods for rapid screening of libraries of different materials
01/13/2005CA2773566A1 Enzyme-catalyzed metal deposition for the enhanced in situ detection of immunohistochemical epitopes and nucleic acid sequences
01/13/2005CA2749227A1 Bead bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries
01/13/2005CA2531321A1 Rna processing protein complexes and uses thereof
01/06/2005US20050003552 Apparatus for monitoring fluid catalytic cracking of hydrocarbons; improving petrochemical refining
01/06/2005US20050003408 Libraries of oligomers labeled with different tags
01/05/2005EP1492618A2 Combinatorial synthesis
01/05/2005EP1390535A4 Combinatorial libraries of monomer domains
01/05/2005EP1364201A4 Ligand sensor devices and uses thereof
12/2004
12/30/2004US20040266854 Inhibitors of cyclin-dependent kinases, compositions and uses related thereto
12/29/2004WO2004113566A2 Disease related protein network
12/28/2004US6834990 Impeller for mixing small volumes of reaction materials
12/23/2004WO2004058633A3 Platinum-free ruthenium-cobalt catalyst formulations for hydrogen generation
12/23/2004WO2004058396A3 Methods for the preparation of catalysts for hydrogen generation
12/23/2004US20040259377 Manipulating micron scale items
12/23/2004US20040259161 functional proteomics; detect a large number of peptides while using far fewer different binders; separate to a spaced apart defined location on an array, wherein members of each class have a common motif; use to identify and diagnose disease related proteins
12/23/2004CA2525179A1 A gene equation to diagnose rheumatoid arthritis
12/22/2004EP1488241A1 Arrays
12/22/2004EP1210607A4 Microelectronic molecular descriptor array devices, methods, procedures, and formats for combinatorial selection of intermolecular ligand binding structures and for drug screening
12/21/2004US6833921 Optical systems and methods for rapid screening of libraries of different materials
12/21/2004US6832737 Combinatorial chemistry; catalyst testing
12/16/2004WO2004086041A3 Universal readout for target indentification using biological microarrays
12/16/2004US20040253640 Using microwave irradiation to heat and immobilize protein chips onto slide; solid supports for disease detection
12/16/2004US20040253635 Contacting libraries with tag (green/blue fluorescent protein, horseradish peroxidase) to form complex, incubating, then identifying competitive binding agents
12/16/2004US20040253612 Selection of proteins using RNA-protein fusions
12/16/2004US20040253578 Solid support comprising immobilized dynamic action reference tools (DART)/bioconjugates for use in isolation and analysis of nucleic acids and polypeptides; drug screening
12/16/2004US20040251334 For combinatorial (i.e., high-throughput) materials research, such as catalysis research, that involves parallel apparatus for simultaneously effecting mechanical treatments such as grinding, mixing, pressing, crushing, sieving, and/or fractionating
12/15/2004EP1485197A1 Process for evaporation and process vessel with integral evaporator
12/15/2004EP1451554A4 Hydrophobic surface chip
12/15/2004EP1112379A4 NOVEL AMPLICON IN THE 20q13 REGION OF HUMAN CHROMOSOME 20 AND USES THEREOF
12/09/2004WO2004106887A2 Quality assurance/quality control for high throughput bioassay process
12/09/2004CA2525681A1 Crystals and structures of c-abl tyrosine kinase domain
12/09/2004CA2523716A1 Human anti-human cd3 binding molecules
12/08/2004EP1484699A2 Protein design automation for protein libraries
12/08/2004EP1483585A1 Encoded self-assembling chemical libraries (esachel)
12/08/2004EP1483576A2 Novel method for detecting and analyzing protein interactions in vivo
12/08/2004EP1483049A1 Guiding structure reactor
12/08/2004EP0833941A4 Polypeptides having a functional domain of interest and methods of identifying and using same
12/08/2004CN1178751C Device for binding target molecule
12/02/2004WO2004104230A1 Reducing microarray variation with internal reference spots
12/02/2004US20040241759 Using encapsulated cells as diagnostic tools for detection of ligand binding proteins and rapid sorting of libraries derived from mixed population of organisms
12/02/2004US20040241675 Method and device for determining and selecting molecule-molecule interactions
12/02/2004US20040241661 Using differential labeling and colorimetric analysis to determine concentration of analytes sample; bioassay for use in gene expression analysis, DNA sequencing, mutation detection, genomics and proteomics
12/02/2004CA2523786A1 A .delta.-12 desaturase gene suitable for altering levels of polyunsaturated fatty acids in oleaginous yeasts
12/01/2004EP1482434A2 Protein design automation for protein libraries
12/01/2004EP1482433A2 Protein design automation for protein libraries
12/01/2004EP1481726A1 The combinatorial hydrothermal synthesis of novel materials
11/2004
11/30/2004US6826487 Defining first experimental space comprising factors of at least two mixtures with common factor, defining second experimental space by deleting duplicate factor combinations from first space, conducting experiment on second space
11/30/2004US6825048 Combinational method for microgram-scale production and characterization of crystalline and amorphous libraries of materials
11/30/2004US6824994 Peptide ligands that mimic sensor kinases and inhibit response regulators
11/30/2004US6824987 Small molecule printing
11/30/2004US6824982 High-throughput-screening method for determining enantioselectivity
11/25/2004WO2004069401B1 Device and process for the simultaneous agitation of reaction mixtures
11/25/2004US20040235064 Peptide complexes comprising reporter fusion which associate through combinations of helical domains to form an antiparallel leucine zipper; protein-protein interaction assays; mimetics
11/25/2004US20040235062 Method of analyzing protein occurring in cell or substance interacting with the protein
11/25/2004US20040235054 Novel encoding method for "one-bead one-compound" combinatorial libraries
11/25/2004US20040235023 For chemoselective, regioselective, stereoselective or enantioselective transformation; solid phase synthesis
11/25/2004US20040232077 Method for determining the binding behavior of ligands which specifically bind to target molecules
11/25/2004CA2523785A1 Small interfering rna libraries and methods of synthesis and use
11/24/2004EP1479771A2 Method to screen phage display libraries with different ligands
11/24/2004EP1479435A1 Screening of organometallic materials for catalysis
11/24/2004EP1392859A4 Isolating cells expressing secreted proteins
11/23/2004US6821737 Detection of modulator of gene expression; obtain genetically engineered cells, incubate with modulator, monitor adjustment in gene expression, adjustment in gene expression indicates presence of modulator
11/23/2004US6821486 Multiautoclave for combinatorial synthesis of zeolites and other materials
11/18/2004US20040229289 Antigen binding peptides (abtides) from peptide libraries
11/18/2004US20040229226 Analyte quantification apparatus comprised of solid support with designated test zones of immobilized capture and calibration ligands; determining cytokine, drug and nucleic acid concentration; diagnosing infection and disease
11/18/2004US20040228768 Apparatus and method for generating a plurality of isolated effluents
11/17/2004EP1476571A1 Complex comprising at least two biospecific elements separated by a nucleic acid linker e.g. for identification of drug delivery candidates. combinatorial library of such complexes
11/17/2004EP1476250A1 High pressure chemistry reactor
11/17/2004EP1476200A2 Compositions and method for regulation of calcium-dependent signalling in brain
11/17/2004EP1401566B1 Reactor for testing catalyst systems
11/17/2004EP0897392B1 Peptides binding sh3 domain of cortactin and their use
11/16/2004US6818411 Retentate chromatography and protein chip arrays with applications in biology and medicine
11/16/2004US6818110 Combinatorial electrochemical deposition and testing system
11/16/2004US6817558 Plurality of catalysts are simultaneously tested in combinatorial chemistry methods
11/11/2004WO2004097408A1 Drug discovery method and apparatus
11/11/2004WO2004097403A1 Ligand profiling and identification
11/11/2004US20040224358 identifying microbial peptides such as cercopins then screening combinatorial libraries; biochemical immobilization; solid phase synthesis
11/11/2004US20040224346 Pool and superpool matrix coding and decoding designs and methods
11/11/2004US20040224334 Computer system for use in designing and predicting probes complimentary to preferential gene sequences; bioinformatics and sequence determmination; genomics
11/11/2004US20040224204 High throughput screening device for combinatorial chemistry
11/11/2004CA2523961A1 Drug discovery method and apparatus
11/11/2004CA2523751A1 Array having substances fixed on support arranged with chromosomal order or sequence position information added thereto, process for producing the same, analytical system using the array and use of these
11/11/2004CA2523501A1 Preservation of rna in a biological sample
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