| Patents for C40B 10 - Directed molecular evolution of macromolecules, e.g. rna, dna or proteins (164) | |
|---|---|
| 03/2009 | |
| 03/12/2009 | US20090068224 Method to identify polypeptide toll-like receptor (tlr) ligands |
| 02/2009 | |
| 02/05/2009 | US20090036653 Methods for the directed expansion of epitopes for use as antibody ligands |
| 02/05/2009 | US20090036315 Device and methods for detecting and quantifying one or more target agents |
| 01/2009 | |
| 01/29/2009 | WO2009014705A1 Compositions and methods for in vivo selex |
| 01/28/2009 | CN101353372A Novel protein molecular orientation evolvement method |
| 12/2008 | |
| 12/31/2008 | WO2008093010A3 Method for the random diversification of a genetic sequence while preserving the identity of some inner segments of said genetic sequence |
| 12/25/2008 | US20080318795 Methods for making character strings, polynucleotides and polypeptides having desired characteristics |
| 12/24/2008 | EP1913140B1 Method for carrying out the selective evolution of proteins in vitro |
| 11/2008 | |
| 11/20/2008 | US20080287304 Mixture of at Least Two Fusion Proteins as Well as Their Production and Use |
| 11/06/2008 | US20080274904 Method of target enrichment |
| 10/2008 | |
| 10/28/2008 | US7442160 Evolving new molecular function |
| 10/16/2008 | CA2683602A1 Selection method for cell internalizing nucleic acids |
| 09/2008 | |
| 09/18/2008 | US20080227650 Incrementally Truncated Nucleic Acids and Methods of Making Same |
| 09/18/2008 | US20080227649 Methods and compositions for cellular and metabolic engineering |
| 09/04/2008 | US20080213770 Using polymerase with reduced exonuclease activity as replicative agent in DNA sequencing |
| 09/03/2008 | CN101258244A Method for carrying out the selective evolution of proteins in vitro |
| 08/2008 | |
| 08/28/2008 | US20080207459 Antibody diversity generation |
| 08/14/2008 | US20080194414 Enrichment and sequence analysis of genomic regions |
| 08/14/2008 | US20080194413 Use of microarrays for genomic representation selection |
| 08/07/2008 | CA2673004A1 Method for the random diversification of a genetic sequence while preserving the identity of some inner segments of said genetic sequence |
| 08/06/2008 | CN101238212A Methods for carrying out the selective evolution of proteinsin vivo |
| 07/2008 | |
| 07/15/2008 | US7399611 Recombinant eubacterial cell containing a polynucleotide encoding an exogenous polypeptide, that has been modified to lack a deformylase gene and/or a Met-tRNA transformylase gene and that expresses a non-formylated polypeptide |
| 07/10/2008 | US20080167194 Protein Design Automation for Protein Libraries |
| 07/10/2008 | US20080167193 In Vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells |
| 05/2008 | |
| 05/29/2008 | US20080125324 Genomic DNA is contacted and hybridized to the arrayed oligonucleotides to form a genomic DNA/oligonucleotide complex; excess genomic DNA is washed away and the haplotype separated genomic DNA is denatured from the oligonucleotide probe and collected |
| 05/08/2008 | US20080108507 Method for in vitro molecular evolution of protein function |
| 04/2008 | |
| 04/23/2008 | EP1913140A2 Method for carrying out the selective evolution of proteins in vitro |
| 04/23/2008 | EP1913139A1 Methods for carrying out the selective evolution of proteins in vivo |
| 04/22/2008 | US7361133 Methods of detection utilizing modified bacteriophage |
| 03/2008 | |
| 03/06/2008 | DE102006039479A1 Programmierbare Oligonukleotidsynthese Programmable oligonucleotide synthesis |
| 02/2008 | |
| 02/14/2008 | US20080038256 having the equal or greater binding activity than that of the parent antibody with reduced immunogenicity in human; HGF/SF (hepatocyte growth factor/scatter factor); cancer |
| 12/2007 | |
| 12/13/2007 | WO2005074569A3 Tracers and assembly for labeling chemical or biological molecules methods and kits using the same |
| 12/06/2007 | WO2005118861A3 Compositions and methods for producing libraries with controlled compositions and screening probabilites |
| 09/2007 | |
| 09/16/2007 | CA2539902A1 Method of enhancing degradation of chitin |
| 09/13/2007 | US20070212781 Method for obtaining new life forms |
| 09/06/2007 | DE102006009000B3 Rechengen Computational gene |
| 06/2007 | |
| 06/27/2007 | EP1799823A2 Method for modulating the evolution of a polypeptide encoded by a nucleic acid sequence |
| 05/2007 | |
| 05/18/2007 | WO2007017229A3 Method for carrying out the selective evolution of proteins in vitro |
| 05/03/2007 | DE102005052275A1 New DNA aptamers specific for compounds that contain the ethylamino group, useful for diagnosis, prevention and treatment of ethanolaminosis, schizophrenia and neurodegeneration |
| 02/2007 | |
| 02/15/2007 | WO2007017229A2 Method for carrying out the selective evolution of proteins in vitro |
| 02/15/2007 | WO2007017228A1 Methods for carrying out the selective evolution of proteins in vivo |
| 02/15/2007 | CA2618160A1 Methods for carrying out the selective evolution of proteins in vivo |
| 02/15/2007 | CA2617982A1 Method for carrying out the selective evolution of proteins in vitro |
| 01/2007 | |
| 01/11/2007 | DE102005037351B3 In vitro method for directed evolution of proteins, useful e.g. in pharmaceutical development, uses expression system for performing translation, transcription and reverse transcription |
| 09/2006 | |
| 09/13/2006 | EP1700915A2 Enzymatic DNA molecules |
| 08/2006 | |
| 08/17/2006 | WO2006046132A3 Method for modulating the evolution of a polypeptide encoded by a nucleic acid sequence |
| 06/2006 | |
| 06/14/2006 | CN1786298A Preparation method of anticell or tissue protein mono clone antibody stock |
| 01/2006 | |
| 01/19/2006 | US20060014250 Descendants of bacteria devoid of N terminal formylation useful for the production of proteins and peptides |
| 11/2005 | |
| 11/08/2005 | US6962807 Descendants of bacteria devoid of N terminal formylation useful for the production of proteins and peptides |
| 06/2004 | |
| 06/23/2004 | EP1268801B1 A method for in vitro molecular evolution of antibody function |
| 04/2004 | |
| 04/07/2004 | EP1404846A1 Method for obtaining cells with new properties |
| 02/2004 | |
| 02/12/2004 | WO2003004656A8 Method for obtaining cells with new properties |
| 10/2003 | |
| 10/28/2003 | US6640191 Library design in combinatorial chemistry by Monte Carlo methods |
| 08/2003 | |
| 08/14/2003 | US20030153038 Method for in vitro molecular evolution of antibody function |
| 07/2003 | |
| 07/31/2003 | US20030143680 Bacterial cells lacking deformylase and/or transformylase |
| 06/2003 | |
| 06/05/2003 | WO2003004656A9 Method for obtaining cells with new properties |
| 01/2003 | |
| 01/16/2003 | WO2003004656A1 Method for obtaining cells with new properties |
| 01/16/2003 | CA2453176A1 Eubacterial host cells devoid of n-terminal formylation and said host cells being useful for the production of proteins and peptides |
| 01/02/2003 | EP1268801A2 A method for in vitro molecular evolution of antibody function |
| 04/2002 | |
| 04/18/2002 | WO2001075091A3 A method for in vitro molecular evolution of antibody function |
| 03/2002 | |
| 03/21/2002 | CA2585083A1 Directed evolution method |
| 10/2001 | |
| 10/11/2001 | WO2001075091A2 A method for in vitro molecular evolution of antibody function |
| 07/2000 | |
| 07/13/2000 | CA2584933A1 Optical sorting method |
| 01/1999 | |
| 01/21/1999 | CA2584453A1 A method for increasing the concentration of nucleic acids |
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