Patents for C12Q 1 - Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions (300,231)
10/1999
10/27/1999EP0951564A1 Method for the detection of compounds that modulate the effects of the obese (ob) protein
10/27/1999EP0951562A1 Fluorescence-labeled substrates and their use to analyze enzyme activity using flow cytometry
10/27/1999EP0951557A1 Methods for generating and screening novel metabolic pathways
10/27/1999EP0951553A2 Adenovirus e4 proteins for inducing cell death
10/27/1999EP0951552A2 Dna and specific proteins or peptides of the neisseria meningitidis species bacteria, method for obtaining them and their biological applications
10/27/1999EP0951551A2 Ligand for receptor activator of nf-kappa b, ligand is member of tnf superfamily
10/27/1999EP0951550A1 Mammalian cytokine related to il10
10/27/1999EP0951547A1 NOVEL SEQUENCES OF p56 PROTEINS WHICH AFFECT K-ATP CHANNELS
10/27/1999EP0951545A2 Human gtp-binding proteins
10/27/1999EP0951541A1 Biomarkers and targets for diagnosis, prognosis and management of prostate disease
10/27/1999EP0951540A2 Antisense nucleic acids and hammerhead ribozymes
10/27/1999EP0951538A2 PARTIAL SEQUENCES OF PURINE BIOSYNTHESIS GENES FROM $i(ASHBYA GOSSYPII) AND THEIR USE IN THE MICROBIAL RIBOFLAVIN SYNTHESIS
10/27/1999EP0951536A1 Synthetic antisense oligodeoxynucleotides and pharmaceutical compositions containing them
10/27/1999EP0951534A1 Nucleic acid sequence encoding beta-c-4-oxygenase from haematococcus pluvialis for the biosynthesis of astaxanthin
10/27/1999EP0951533A1 Vectors and methods for the mutagenesis of mammalian genes
10/27/1999EP0951469A1 Novel compounds
10/27/1999EP0951297A1 Detection of antigens via oligonucleotide antibody conjugates
10/27/1999EP0951296A1 NOVEL FtsL
10/27/1999EP0853630A4 Detecting genetic predisposition to periodontal disease
10/27/1999EP0769144B1 Assay for inhibitors of dp-1 and other dp proteins
10/27/1999EP0715655B1 Method of detecting and counting microorganisms
10/27/1999EP0682716A4 Rna assays using rna binary probes and ribozyme ligase.
10/27/1999EP0590082B1 Antisense oligonucleotide inhibition of the ras gene
10/27/1999EP0584145B1 Process for the in vitro diagnosis of chromosomal anomalies correlated with cmt1a disease
10/27/1999CN1233326A Process for determining the status of an organism by peptide measurement
10/27/1999CN1233290A Antifungal proteins, DNA coding therefore, and hosts incorporating same
10/26/1999US5974164 Computer-aided visualization and analysis system for sequence evaluation
10/26/1999US5973330 Fluorescence detection apparatus
10/26/1999US5973233 Cytoplasmic male sterility system production canola hybrids
10/26/1999US5973138 Method for purification and manipulation of nucleic acids using paramagnetic particles
10/26/1999US5973133 Mutant S182 genes
10/26/1999US5973131 Diagnosis of systemic infections of penicillium marneffei by detecting the presence of the specific antibodies as well as the pmap1 protein antigen.
10/26/1999US5973124 Native egg-white, recombinant, deglycosylated, bacterial or truncated avidin/strepavidin or derivatives with modified tyrosine at binding site, resulting in reduced pka; for reversible binding of biotin; reuse of chromatography matrix
10/26/1999US5973119 Cyclin E genes and proteins
10/26/1999US5972716 With sample tube having surface roughness which reduces background due to contamination of tube holder in apparatus; for polymerase chain reactions
10/26/1999US5972704 HIV nef targeted ribozymes
10/26/1999US5972699 Method and reagent for inhibiting herpes simplex virus replication
10/26/1999US5972693 Apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
10/26/1999US5972692 For sensitive, safe, convenient, rapid detection by hybridization; electrode with single stranded nucleic acid probe immobilized on surface, reaction vessel for denatured sample, washing means, vessel for storage of detection means
10/26/1999US5972680 An aminopeptidase which is involved in insulin regulation.
10/26/1999US5972676 Diagnosis and treatment of AUR-1 and/or AUR-2 related disorders
10/26/1999US5972674 May be used, for example, to identify antibodies and other agents that inhibit or activate signal transduction via the nf-.kappa.b cascade.
10/26/1999US5972671 Fructosyl amino acid oxidase and process for producing the same
10/26/1999US5972667 Applicable to the temperature-sensitive transformation of cells with the specific synthesis or activation of bio-molecules such as enzymes and/or structural heat shock proteins.
10/26/1999US5972664 Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
10/26/1999US5972651 Polynucleotides and polypeptides of the fifty-four homologue family, (ffh); vectors and transformed host cells; ffh are components of protein secretory apparatus and their inhibition of function is deleterious to bacteria cells
10/26/1999US5972649 Polynucleotide sequence encoding human multiple endocrine neoplasia type 1 protein
10/26/1999US5972646 Isolated nucleic acid molecule which codes for a 32 kDa protein having 11-cis retinol dehydrogenase activity, and which associates with P63, a portion of a retinol binding protein receptor
10/26/1999US5972641 Milk sample added to a culture medium comprising a fluorogenic substrate which forms a fluorogenic product when acted on by coliform bacteria; incubating; irradiating; measuring fluoresence, comparing to single threshold value
10/26/1999US5972640 Methods for identifying antimitotic agents
10/26/1999US5972639 Screening for modulators by incubating cell lysate at acid ph with benzothiazole substrate, raising ph above 7, measuring fluorescence as indicator; for angiogenesis inhibitors, antitumor agents, treatment of vision defects
10/26/1999US5972638 Spraying recombinant bacteria on surface of ground, examining ground to detect visible signal formed after period of time
10/26/1999US5972637 Determining the organic content of a fluid
10/26/1999US5972636 ATP-dependent protease and use of inhibitors for same in the treatment of cachexia and muscle wasting
10/26/1999US5972635 Sulfonic acid group buffered dry analytical element for quantitative analysis of creatine kinase or its MB isozyme
10/26/1999US5972631 Coating substrate with sucrose transglycosylase and amylose, dextran or levan; incubating with sample; measuring increase in amount of amylose, dextran or levan using immunoassay; noninvasive diagnosis of gastric damage
10/26/1999US5972630 Determining the presence of an analyte in sample; complexing two complementary specific binding members; the members are ligand and receptor in solution, analyzing enzyme activity, evaluating activity by amount of analyte in sample
10/26/1999US5972627 Method of purifying a population of cells enriched for dendritic and/or lymphoid progenitors and populations of cells obtained thereby
10/26/1999US5972620 Method of isolating ribotopes and proteotopes
10/26/1999US5972619 Sequence generation can be obtained for a large complex mammalian genome in a single process.
10/26/1999US5972618 Detection of mutations in nucleic acids by chemical cleavage
10/26/1999US5972617 Oligonucleotides and methods for determining beer spoilage ability of lactic acid bacteria
10/26/1999US5972615 A means for screening pharmaceuticals effective in the treatment of prostate cancer.
10/26/1999US5972614 To screen patients for sensitivity to specific drugs. the present invention also relates to the isolation of naturally occurring gene targets for pharmaceutical development.
10/26/1999US5972613 Methods of nucleic acid isolation
10/26/1999US5972612 Analyzing nucleic acid sequences by measuring the binding interaction between two nucleic acid molecules, one nucleic acid is immobilized on a solid phase surface, binding affinity is determined by complementary annealing
10/26/1999US5972611 Hybridization carrier and a process for preparing the same
10/26/1999US5972610 Use of nucleic acid analogues in the inhibition of nucleic acid amplification
10/26/1999US5972609 Utrophin gene promotor
10/26/1999US5972608 The action of a chromatin remodeling enzyme leads to the enhanced or decreased accessibility of nucleosomal dna sequences and thus affects nuclear processes that utilize dna as a substrate.
10/26/1999US5972607 Methods for nucleic acid amplification with thermostable ribonuclease H
10/26/1999US5972606 A polypeptide; treating osteoporosis, eating disorders, brain disorders, adult respiratory disease syndrome, huntington'sdisease, ulcers, cardiovascular disorders, parkinson's disease;
10/26/1999US5972605 Assays for regulators of mammalian telomerase expression
10/26/1999US5972604 DNA sequence-based HLA typing method
10/26/1999US5972602 Quantitative PCR-based method of gene detection
10/26/1999US5972601 Isolated polynucleotide molecules useful for analyzing alloantigen phenotypes, to peptides encoded by these molecules, and to the diagnostic and therapeutic uses thereof relating to the ?pen? human platelet polymorphism.
10/26/1999US5972600 Separation of active complexes
10/26/1999US5972599 High affinity nucleic acid ligands of cytokines
10/26/1999US5972598 Methods for preventing multidrug resistance in cancer cells
10/26/1999US5972597 Methods using modified vaccinia virus
10/26/1999US5972596 Nucleic acid constructs containing HIV genes with mutated inhibitory/instability regions and methods of using same
10/26/1999US5972595 Enzyme assay using a solid phase substrate
10/26/1999US5972386 A solid materix having adsorbed thereto a protein denaturing agent, a component for analysis of the sample of genetic material and a retaining agent
10/26/1999US5972348 Nickel binding protein and its encoding dna isolated from helicobacter pylori; useful as vaccine, diagnostic, drug target, and therapy in itself
10/26/1999US5972338 ?tie? or ?tie? are acronyms, which stand for ?tyrosine kinase containing ig and egf homology domains?; present invention concerns novel human tie ligand homologues with powerful effects on vasculature; antitumor agents
10/26/1999US5972337 46 kilodalton human milk fat globule (HMFG) antigen, fragments and fusion protein
10/26/1999US5972294 Reagent test strip for determination of blood glucose
10/26/1999US5972199 Electrochemical analyte sensors using thermostable peroxidase
10/26/1999CA1340802C Senile amyloid precursor protein and an antibody specific for the same
10/24/1999CA2266755A1 Method for sequencing of nucleic acid polymers
10/21/1999WO1999053423A1 Expert system for analysis of dna sequencing electropherograms
10/21/1999WO1999053323A1 Diagnostic method for bipolar disorder
10/21/1999WO1999053319A2 High-density, miniaturized arrays and methods of manufacturing same
10/21/1999WO1999053316A1 Methods for disease diagnosis from stool samples
10/21/1999WO1999053304A1 Method for electroelution of a biological sample and implementing device
10/21/1999WO1999053301A1 Sensor probe for determining hydrogen peroxide concentration and method of use thereof
10/21/1999WO1999053295A1 Assays for the detection of microtubule depolymerization inhibitors
10/21/1999WO1999053103A1 Diagnosis of multiple sclerosis and other demyelinating diseases
10/21/1999WO1999053102A1 Analysis of polynucleotide sequence
10/21/1999WO1999053101A1 Identification of genetic targets for modulation by oligonucleotides and generation of oligonucleotides for gene modulation