Patents for C12Q 1 - Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions (300,231)
11/1999
11/09/1999US5981208 Diagnostic assay for Alzheimer's disease based on the proteolysis of the amyloid precursor protein
11/09/1999US5981207 Caged enzyme substrates as probes for reporter enzyme activity
11/09/1999US5981206 Storage stable diagnostic element of acidic buffer, nonhygroscopic alkaline earth metal salt of an aryl phosphate ester, and a diazonium or tetrazolium salt
11/09/1999US5981205 Nuclear Dbf2- related (Ndr) kinases
11/09/1999US5981200 A donor and an acceptor fluorescent protein moiety coupled together by a peptide linker; exhibit fluorescence resonance energy transfer which is eliminated upon cleavage of peptide linker; for enzymatic assays
11/09/1999US5981193 Human neuronal nicotinic acetylcholine receptor compositions and methods employing same
11/09/1999US5981191 Determining the frequency of target mutation arising in a static cell population; growing mutant cells with detectable phenotype in nonkilling environment, induce cell cycle static phase, detect phenotypes
11/09/1999US5981190 Analysis of gene expression, methods and reagents therefor
11/09/1999US5981188 Method for identifying agents that modulate transcription of human cytomegalovirus polymerase
11/09/1999US5981187 Selection method involving acetal coenzyme a synthetase in calves
11/09/1999US5981186 Method and apparatus for DNA-sequencing using reduced number of sequencing mixtures
11/09/1999US5981185 Determining size of duplicated nucleotide repeats in sample; bringing sample into contact with an array of oligonucleotides attached to a support, hybridization, eluting hybrids from support, sizing nucleotide repeats
11/09/1999US5981184 Kit for screening enzyme inhibitors including recombinant organism transformed with gene controlled by inducible promoter, an inducer, cations which impair metabolism and measuring device
11/09/1999US5981183 Using heat resistant enzyme to increase copy number of nucleotide sequence; hybridizing rna primer, separating template dna, digestion, elongating, obtaining double stranded dna, and making further copies; increased stability
11/09/1999US5981182 Vector constructs for the selection and identification of open reading frames
11/09/1999US5981179 Continuous amplification reaction
11/09/1999US5981178 Diagnosing cystic fibrosis in vitro to determine if human subject is carrier of the genetic disorder; obtaining sample and analyzing genetic composition
11/09/1999US5981176 Allele primer complementary to a target dna sequence and immobilized to a solid support; tool for diagnosis and genetic analysis; detection of genetic disorders such as sickle cell anemia and thalasemia
11/09/1999US5981175 Forming co-lipofection complex of a cationic lipid, a polynucleotide larger than 50 kilobases, and an unlinked second polynucleotide of selectable marker gene expression cassette; contacting a mammalian cell; incorporating dna
11/09/1999US5981174 Determining the metabolic phenotype of a human or a cell; removing dna sample from source, analyzing for mutants at specific genetic positions, classifying metabolic phenotype; for clinical trials and models of new drug interactions
11/09/1999US5981173 Human urogenital virus dna; for diagnosis and for developing models for cancer of urogenital system
11/09/1999US5981172 Probe for viral untranslated region; detecting viral nucleic acids; deveolping vaccines and antibodies to use as diagnostic tool in detecting presence of virus
11/09/1999US5981171 Detecting dna sequences in heterogenous biological sample by hybridizing with probe, separating unhybridized sequences, detecting presence labeled target sequence; screening for oncogenes
11/09/1999US5981169 Method for closing a cuvette
11/09/1999US5981167 Incubating protease and substrate modified with terminal binding moiety, contacting solution with ligand coupled to sensor chip and which reversably binds modified substrate, measuring mass of complex; reduction indicates cleavage
11/09/1999US5981165 Exogenous activation and expression of tyrosine hydroxylase in neural cells; culturing mammalian cells of central nervous system; treatment for parkinson's disease and other nervous system disorders
11/09/1999US5981164 Method for detecting Porphyromonas gingivalis
11/09/1999US5980910 Useful in coating polymeric medical materials to prevent colonization by coagulase-negative staphylococcal strains, in assays for the detection of such bacteria
11/09/1999US5980909 Epitopic regions of pneumococcal surface protein A
11/09/1999US5980891 Schizosaccharomyces-specific polypeptides
11/09/1999US5980828 For rapid sampling and detection of bacteria during food processing
11/09/1999US5979668 Filtration device for quantitation of microorganism contaminated liquids
11/09/1999CA2133765C Cyclic-substituted unsymmetrical cyanine dyes
11/09/1999CA2087976C Process for producing magnetically responsive polymer particles and application thereof
11/09/1999CA2041896C Stabilized uric acid reagent
11/07/1999CA2270405A1 Polymorphisms associated with hypertension
11/04/1999WO1999056129A1 Methods of selecting internalizing antibodies
11/04/1999WO1999056119A1 Dextran-coated surface
11/04/1999WO1999056103A1 Sample collection method
11/04/1999WO1999055917A1 Mixed cell diagnostic systems
11/04/1999WO1999055916A1 Methods, kits and compositions for detecting and quantitating target sequences
11/04/1999WO1999055915A2 IDENTIFICATION OF POLYMORPHISMS IN THE PCTG4 REGION OF Xq13
11/04/1999WO1999055914A1 Methods and compositions pertaining to pd-loops
11/04/1999WO1999055913A2 Reduced complexity nucleic acid targets and methods of using same
11/04/1999WO1999055912A1 Primer extension methods for detecting nucleic acids
11/04/1999WO1999055909A1 A FREQUENT MUTATION IN THE CYSTATHIONINE β-SYNTHASE GENE INCREASES RISK FOR CORONARY ARTERY DISEASE
11/04/1999WO1999055908A2 Nucleotide sequences for detecting enterohemorrhagic escherichia coli (ehec)
11/04/1999WO1999055907A2 Method for screening antimycotic substances using essential genes from s. cerevisiae
11/04/1999WO1999055906A2 Gene screening methods and related assays
11/04/1999WO1999055905A1 ASSAY FOR METHYLATION IN THE GST-Pi GENE
11/04/1999WO1999055904A1 Screening assay for identifying therapeutics useful for modulating body weight
11/04/1999WO1999055903A1 Membrane-permeant phosphoinositides
11/04/1999WO1999055902A1 Diagnostic markers of human female infertility
11/04/1999WO1999055900A2 Gcp
11/04/1999WO1999055899A1 Methods for transducing fusion molecules
11/04/1999WO1999055886A1 Function-based gene discovery
11/04/1999WO1999055878A1 Novel nucleic acids and polypeptides related to a farnesyl-directed cysteine carboxymethyltransferase
11/04/1999WO1999055873A2 Basb006 polynucleotide(s) and polypeptides from neisseria meningitis
11/04/1999WO1999055867A1 Delayed rectifier potassium channel subunit
11/04/1999WO1999055859A2 Cd40-interacting and traf-interacting proteins
11/04/1999WO1999055853A1 Novel immortalized hepatic cell line originating in humans
11/04/1999WO1999055846A1 Recombinant secoisolariciresinol dehydrogenase, and methods of use
11/04/1999WO1999055845A1 Cellular and animal models for diseases associated with altered mitochondrial function
11/04/1999WO1999055844A2 Methods for modulating differentiation
11/04/1999WO1999055841A2 Process for obtaining stem cells
11/04/1999WO1999055836A1 BACTERIA OVERPRODUCING α-ACETOLACTATE AND METHOD FOR OBTAINING SAME
11/04/1999WO1999055832A2 Nucleic acid encoding rate agouti related protein
11/04/1999WO1999055734A1 A g-protein coupled 7tm receptor (axor-1)
11/04/1999WO1999055733A1 Cloning of a novel 7tm receptor axor-2
11/04/1999WO1999055732A1 A novel g-protein coupled receptor
11/04/1999WO1999055729A1 STAPHYLOCOCCUS AUREUS pyrH POLYPEPTIDES AND POLYNUCLEOTIDES
11/04/1999WO1999055716A1 A gene associated with nijmegen breakage syndrome, its gene product and methods for their use
11/04/1999WO1999055356A1 A method of detecting drug-receptor and protein-protein interactions
11/04/1999WO1999055343A1 Cnre binding factors and uses thereof
11/04/1999WO1999047702A3 Method and device for identifying a tag
11/04/1999WO1999046381A3 Human fgf gene and gene expression products
11/04/1999WO1999044063A3 Tumor tissue microarrays for rapid molecular profiling
11/04/1999WO1999044062B1 Cellular arrays for rapid molecular profiling
11/04/1999WO1999042597A9 Monovalent, multivalent, and multimeric mhc binding domain fusion proteins and conjugates, and uses therefor
11/04/1999WO1999042595A9 Mismatch cleavage enzymes from extreme thermophiles and uses thereof
11/04/1999WO1999042477A8 Transporter protein for saccharide-coupled medicaments
11/04/1999WO1999042090A3 Treating cancer
11/04/1999WO1999039006A3 Methods to identify polynucleotide and polypeptide sequences which may be associated with physiological and medical conditions
11/04/1999WO1999037788A9 Diagnosis and treatment of aur1 and/or aur2 related disorders
11/04/1999WO1999034004A3 Metastatic breast and colon cancer regulated genes
11/04/1999WO1999033981A3 Human signal peptide-containing proteins
11/04/1999WO1999019481A3 Mammalian genes involved in viral infection and tumor suppression
11/04/1999DE19818360A1 Dextranbeschichtete Oberfläche Dextran surface
11/04/1999CA2330560A1 Methods for transducing fusion molecules
11/04/1999CA2330277A1 Reduced complexity nucleic acid targets and methods of using same
11/04/1999CA2329982A1 Membrane-permeant phosphoinositides
11/04/1999CA2329975A1 Process for obtaining stem cells
11/04/1999CA2329857A1 A human derived immortalized liver cell line
11/04/1999CA2327504A1 Cd40-interacting and traf-interacting proteins
11/04/1999CA2327352A1 Novel serine protease capable of selective cleavage of insulin-like growth factor binding protein
11/04/1999CA2327176A1 Methods for modulating differentiation
11/04/1999CA2326697A1 Primer extension methods for detecting nucleic acids
11/04/1999CA2326627A1 Nucleotide sequences for detecting enterohemorrhagic escherichia coli (ehec)
11/04/1999CA2326601A1 Ese genes and proteins
11/04/1999CA2326380A1 Recombinant secoisolariciresinol dehydrogenase, and methods of use