| Patents for C12Q 1 - Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions (300,231) |
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| 01/25/2000 | US6018105 Nucleotide sequences; for expressing modified forms of herbicide target enzymes for herbicide resistant plants |
| 01/25/2000 | US6018042 An oligonucleotide derivative capable of modulating the biosynthesis of human s-adenosylmethionine decarboxylase enzyme; antiproliferative/antitumor/antimetastasis agents |
| 01/25/2000 | US6018041 Oligonucleotide probes of known sequences and length n; each having continuous overlapping sequences of length n-1 to other probes; hybridizing probes to a nucleic acid determines the sequences of the nucleic acid that is longer than n |
| 01/25/2000 | US6018027 A polypeptide encoding a nucleic acid having morphology of herpes virus and a double stranded dna genome designated as a new human b lymphotropic virus; diagnosis and therapy |
| 01/25/2000 | US6018025 Compositions and methods for the treatment and diagnosis of cardiovascular disease using rchd528 as a target |
| 01/25/2000 | US6017871 Protease-containing cleaning compositions |
| 01/25/2000 | US6017769 Non-enzymatic methods of generating chemiluminescence from acridan alkenes |
| 01/25/2000 | US6017768 For screening agonists or antagonists of alpha adrenergic receptors, dopamine receptors, sigma opiate receptors, potassium ion channels, carbonic anhydrase inhibitors; for treatment of glaucoma |
| 01/25/2000 | US6017763 G-beta-gamma regulated phosphatidylinositol-3' kinase |
| 01/25/2000 | US6017756 A catalytic rna enzyme, or ribozyme; therapy for hepatitis b |
| 01/25/2000 | US6017744 Human N-acetyl transferase |
| 01/25/2000 | US6017739 Amplifying the normal nucleic acid and the mutant nucleic acid in the sample, and a labeled nucleic acid standard comprising an amplification label capable of bindidng to a solid support, then mixing together samples allowing competitive |
| 01/25/2000 | US6017738 Detecting and amplifying target nucleic acid sequences in test or biological sample; using one primer immobilized to a solid phase support and a second primer with a detectable label; both primers are hybridizable to the target molecule |
| 01/25/2000 | US6017735 A fusion polypeptide having a herpes virus virion protein and a second protein selected from cell cycle control, suicide protein, antigenic sequences, immunomodulating or therapeutic protein; antiproliferative/anticarcinogenic agents |
| 01/25/2000 | US6017729 Receptor activator of NF-κB |
| 01/25/2000 | US6017723 Method for isolating inhibitors of protease activity |
| 01/25/2000 | US6017722 Identifying toxic substances in a sample by applying the toxicant containing sample to a separation phase matrix, chromotography paper; then exposing the sample sheet to a luminescent bacteria, detecting inhibition of luminescence |
| 01/25/2000 | US6017716 Mixing biological sample with an isolated protein and determining binding of antibodies in sample to protein; antibody binding idicates melanoma |
| 01/25/2000 | US6017711 Bacterial diagnostic probe |
| 01/25/2000 | US6017709 DNA replication templates stabilized by guanine quartets |
| 01/25/2000 | US6017707 Diagnostic kit including a tracer-labelled oligonucleotide probe reactive with reagent, and a reagent of linear carbon-to-carbon backbone polymer with pendant oligonucleotides which hybridize to sequence of interest |
| 01/25/2000 | US6017705 Nucleic acid molecules that codes for tumor rejection antigens; diagnosis and screening for possible presence of lymphoma, or head and neck squamous cell carcinoma, skin and mammary carcinomas |
| 01/25/2000 | US6017704 Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| 01/25/2000 | US6017703 Screening for bladder cancer by detecting the presences of a tumor-associated human complement factor h antigen in a biological sample by hybridization and amplification by polymerase chain reaction |
| 01/25/2000 | US6017702 Sanger sequencing which reduces variability of peak heights in generated electropherogram |
| 01/25/2000 | US6017701 Preparing tester and driver nucleic acids, complexing with adpator nucleic acids, mixing complexes formimg double stranded variations, adding reagent and replicating only double-stranded adaptor:tester nucleic acid complexes |
| 01/25/2000 | US6017700 Cationic oligonucleotides, and related methods of synthesis and use |
| 01/25/2000 | US6017699 PCR identification and quantification of important Candida species |
| 01/25/2000 | US6017696 Controlling nucleic acid hybridization by connecting multiple electrical sources to several location where a plurality of nucleic acids with target nucleic acids are attached, apply a negative potential, removing non specific nucleic acid |
| 01/25/2000 | US6017695 A polynucleotide sequence that encodes a human brain glycoprotein, contactin; to study signal transmissions, cell morphology, cell metabolism and cell adhesion |
| 01/25/2000 | US6017694 Culturing cells carrying a nucleic acid encoding a matrix protein fused to a maltose binding protein and glutathione transferase, express and measure protein interaction, then add test sample to the expressed protein, measure interaction |
| 01/25/2000 | US6017693 Analyzing oligonucleotide fragments, comparing to calculated mass spectra of nucleotide sub-sequences stored in database, calculating closeness-of-fit measure to determine best matches |
| 01/25/2000 | US6017692 Methods of detecting a malignant cell in a biological sample comprising measuring Mxi gene expression alterations |
| 01/25/2000 | US6017435 Molecular imaging |
| 01/25/2000 | CA2184005C Novel phosphoramidate and phophorothioamidate oligomeric compounds |
| 01/25/2000 | CA2130751C Apparatus and process for electroelution of a gel containing charged macromolecules |
| 01/25/2000 | CA2095070C Rna amplification process requiring a single manipulation step |
| 01/25/2000 | CA2003508C Monodisperse superparamagnetic particles for use in nucleic acid analyses |
| 01/25/2000 | CA1340881C Nucleic acid probes for detecting human papillomavirus |
| 01/25/2000 | CA1340878C Production of human t-cell leukemia (lymphotropic) retrovirus (htlv-i) envelope protein fragments in bacteria and use in seroepidemiological survey of human lymphoid malignancies |
| 01/20/2000 | WO2000003447A1 Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration |
| 01/20/2000 | WO2000003248A1 Method for identifying a presenilinase inhibitor |
| 01/20/2000 | WO2000003246A2 A system for cell-based screening |
| 01/20/2000 | WO2000003244A2 Immortalized human keratinocyte cell line |
| 01/20/2000 | WO2000003222A2 Method for fabricating biosensors using hydrophilic polyurethane |
| 01/20/2000 | WO2000003039A1 Methods for determining cross-hybridization |
| 01/20/2000 | WO2000003038A2 Method and reagents for analyzing the nucleotide sequence of nucleic acids |
| 01/20/2000 | WO2000003037A1 Screening arrays of nucleotides to determine correspondence with both sequence and physical properties of a probe |
| 01/20/2000 | WO2000003036A1 Method of screening for potential anti-metastatic and anti-inflammatory agents using mammalian heparanase as a probe |
| 01/20/2000 | WO2000003035A1 Evacuated sensor device for detecting microorganisms in blood samples, and method therefor |
| 01/20/2000 | WO2000003034A2 Novel polycyclic aromatic fluorogenic substrates for hydrolases |
| 01/20/2000 | WO2000003033A1 Use of fluorescent reagents in identification of cancerous cells and activated lymphocytes |
| 01/20/2000 | WO2000003025A2 Method of genetic modification of a wild type viral sequence |
| 01/20/2000 | WO2000003024A2 Alleles of the human mu opioid receptor, diagnostic methods using said alleles, and methods of treatment based thereon |
| 01/20/2000 | WO2000003023A1 Usurpin, a mammalian ded-caspase homologue that precludes caspase-8 recruitment and activation by the cd-95 (fas, apo-1) receptor complex |
| 01/20/2000 | WO2000003016A1 Immunological reagent specifically interacting with the extracellular domain of the human zeta chain |
| 01/20/2000 | WO2000003015A2 Human transport protein homologs |
| 01/20/2000 | WO2000002999A2 Medium and matrix for long-term proliferation of cells |
| 01/20/2000 | WO2000002923A1 Method of treating disorders by modulating the interaction of natural killer receptors on t cells with their respective ligands |
| 01/20/2000 | WO2000002919A1 Growth hormone secretagogue related receptors and nucleic acids |
| 01/20/2000 | WO2000002908A2 Inhibition of alopecia |
| 01/20/2000 | WO2000002899A1 Method of using an improved peptide nucleic acid universal library to optimize dna sequence hybridation |
| 01/20/2000 | WO2000002897A2 Delta cleavage products and methods based thereon |
| 01/20/2000 | WO2000002895A1 Arylsulfone linkers for mass spectrometric analysis |
| 01/20/2000 | WO2000002894A1 Silicon-containing linkers for nucleic acid mass markers |
| 01/20/2000 | WO2000002893A1 Metal ion-binding mass markers for nucleic acids |
| 01/20/2000 | WO2000002583A1 Method of treating disorders by modulating the interaction of natural killer receptors on t cells with their respective ligands |
| 01/20/2000 | WO2000002520A2 T-lymphocyte exchange |
| 01/20/2000 | WO1999060408A3 Assay involving protein binding to 3' untranslated mrna sequences |
| 01/20/2000 | WO1999060007A3 Libraries of oligomers labelled with different tags |
| 01/20/2000 | WO1999058978A3 Tumour markers |
| 01/20/2000 | WO1999058971A3 Methods for quantitating low level modifications of nucleotide sequences |
| 01/20/2000 | WO1999058641A8 Nt2lp, novel g-protein coupled receptors having homology to neurotensin-2 receptors |
| 01/20/2000 | WO1999058559A3 Factors affecting tumor necrosis factor receptor releasing enzyme activity |
| 01/20/2000 | WO1999057145A3 Human bmp-4 promoter and method for exploring bone-related substance by using the same |
| 01/20/2000 | WO1999055913A3 Reduced complexity nucleic acid targets and methods of using same |
| 01/20/2000 | WO1999051742A3 Dadd, death activator death domain protein |
| 01/20/2000 | WO1999050659A3 Rapid method for detecting micro-organisms and evaluating antimicrobial activity |
| 01/20/2000 | WO1999050445A3 Detection method for tumor cells |
| 01/20/2000 | WO1999049037A3 Protein phosphatase-related molecules |
| 01/20/2000 | WO1999048916A3 Hypoxia-inducible human genes, proteins, and uses thereof |
| 01/20/2000 | WO1999047674A3 Compounds and methods for therapy and diagnosis of lung cancer |
| 01/20/2000 | WO1999041386A3 Novel endo-xylogalacturonase |
| 01/20/2000 | WO1999038964A3 Promoter regions of the mouse and human telomerase rna component genes |
| 01/20/2000 | DE19831420A1 Chimeric promoter constructs with binding sites for recombinant transcription factors useful for producing agents to treat cancer, inflammation, allergy and autoimmune diseases |
| 01/20/2000 | CA2385987A1 Arylsulfone linkers for mass spectrometric analysis |
| 01/20/2000 | CA2385970A1 Silicon-containing linkers for nucleic acid mass markers |
| 01/20/2000 | CA2385962A1 Metal ion-binding mass markers for nucleic acids |
| 01/20/2000 | CA2383952A1 Photoluminescent semiconductor materials |
| 01/20/2000 | CA2340178A1 Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration |
| 01/20/2000 | CA2337208A1 Evacuated sensor device for detecting microorganisms in blood samples, and method therefor |
| 01/20/2000 | CA2335564A1 Novel polycyclic aromatic fluorogenic substrates for hydrolases |
| 01/20/2000 | CA2335382A1 Method of screening for potential anti-metastatic and anti-inflammatory agents using mammalian heparanase as a probe |
| 01/20/2000 | CA2335090A1 Immunological reagent specifically interacting with the extracellular domain of the human zeta chain |
| 01/20/2000 | CA2334168A1 Inhibition of alopecia |
| 01/20/2000 | CA2333893A1 Delta cleavage products and methods based thereon |
| 01/20/2000 | CA2333857A1 Growth hormone secretagogue related receptors and nucleic acids |
| 01/20/2000 | CA2332346A1 Usurpin, a mammalian ded-caspase homologue that precludes caspase-8 recruitment and activation by the cd-95 (fas, apo-1) receptor complex |
| 01/20/2000 | CA2332344A1 Method for identifying a presenilinase inhibitor |
| 01/20/2000 | CA2332307A1 Human transport protein homologs |