Patents for C12Q 1 - Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions (300,231)
03/2000
03/01/2000EP0981637A1 Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same
03/01/2000EP0981633A2 Hybrid molecules for optically detecting changes in cellular microenvironments
03/01/2000EP0981629A1 Forms of prostate specific antigen and methods for their detection
03/01/2000EP0981627A1 Purified telomerase
03/01/2000EP0981625A2 $i(ENTEROCOCCUS FAECALIS) POLYNUCLEOTIDES AND POLYPEPTIDES
03/01/2000EP0981619A1 T1/st2-receptor ligand iii
03/01/2000EP0981615A1 Protein kinase c inhibitor-like protein (ipkc-2)
03/01/2000EP0981614A1 Prostate cancer-specific marker
03/01/2000EP0981610A2 Compositions for treatment of disorders involving programmed cell death
03/01/2000EP0981609A2 A method to clone mrnas and display of differentially expressed transcripts (dodet)
03/01/2000EP0981550A1 Methods for eosinophil depletion and compositions therefor
03/01/2000EP0981547A1 Tumor-associated antigen
03/01/2000EP0981544A2 Anti-bacterial methods and materials
03/01/2000EP0981541A1 Psca: prostate stem cell antigen
03/01/2000EP0981537A1 An infectious clone for human parainfluenza virus type 3
03/01/2000EP0981535A1 Methods for production and purification of nucleic acid molecules
03/01/2000EP0981521A2 Novel macrocyclic compounds as metalloprotease inhibitors
03/01/2000CN1246158A Method of PCR testing of pooled blood samples
03/01/2000CN1246153A Mutant alpha-amylase comprising modification at residues corresponding to A210, H405 and/or T412 in Bacillus Licheniforms
03/01/2000CA2246791A1 Treatment of endothelium with somatostatin analogues
02/2000
02/29/2000US6031150 Genome with homozygous disruption of gene by selectable marker; for studying non-insulin dependent diabetes mellitus and persistent hyperinsulinemic hypoglycemia of infancy
02/29/2000US6031092 Preparation of phosphorothioate oligomers
02/29/2000US6031090 Molecular cloning of a 7TM receptor (GPR31A)
02/29/2000US6031087 Nucleotide sequences or complementary sequences of a type ii serine protease inhibitor precursor from a plant; for pathogen resistant transgenic plants
02/29/2000US6031077 For prevention and treatment of heartworm infections; parasiticides; anthelmintics
02/29/2000US6031072 Compounds and methods for modulating cell adhesion
02/29/2000US6030835 Methods and composition for identifying group a streptococcus
02/29/2000US6030832 Dna sequence of protein which interacts with domain of tumor suppressor protein
02/29/2000US6030827 Chemical sensor with an enzyme layer, a diffusion layer and an analyte barrier layer positioned over the diffusion layer; for controlled analyte flux to diffusion layer
02/29/2000US6030825 Cyclophilin-type peptidyl-prolyl cis/trans isomerase
02/29/2000US6030822 Amino acid sequence; for treating skeletal muscle diseases, alzheimer's disease, or peripheral neuropathies in a mammal with an agonist or antagonist of kinase activity; antidiabetic agents
02/29/2000US6030814 Reverse transcription method
02/29/2000US6030813 Phosphoramidate-phosphodiester oligonucleotide chimera utilized as primers
02/29/2000US6030811 Polynucleotides encoding a human mystrophin clone, HSABH01
02/29/2000US6030808 Nucleic acids encoding receptor recognition factor stat 3 and methods of use thereof
02/29/2000US6030803 Dibenzodihydropyridinecarboxylic esters and their use in chemiluminescent assay methods
02/29/2000US6030802 Liquid reagent set for L-lactate determination
02/29/2000US6030801 Amino acid sequence of enzyme; for screening a library for molecules which bind the polypeptide; diagnosis, treatment or prevention of cancer, immune and reproductive disorders; anticarcinogenic agents
02/29/2000US6030799 Immunoassays for detecting chlamydial antigens or antibodies thereto using recombinant or synthetic major outer membrane protein polypeptides as substitute antigens
02/29/2000US6030793 Immunoassay for detecting a cell proliferation disorder using antibodies against proteins with a defined expression in prostate tissue; for diagnosis and monitoring the stage of malignancy
02/29/2000US6030787 Hybridization assay using self-quenching fluorescence probe
02/29/2000US6030785 Incubating a mixture containing pkr protein kinase, a viral protein containing an interferon sensitivity determining region, and an agent to be tested; then measuring the protein kinase activity where activity indicates an antiviral agent
02/29/2000US6030784 Method for simultaneous identification of differentially expressed mRNAS and measurement of relative concentrations
02/29/2000US6030782 Covalent attachment of nucleic acid molecules onto solid-phases via disulfide bonds
02/29/2000US6030781 Electric field amplified oligonucleotide ligase analysis
02/29/2000US6030780 Screening drugs that modulate ability of signal transducers and activators of transcription protein dimers to interact and bind dna binding sites by measuring affinity of n-terminal domain to weak and strong binding sites
02/29/2000US6030779 Screening for novel bioactivities
02/29/2000US6030778 Diagnostic assays and kits for body mass disorders associated with a polymorphism in an intron sequence of the SR-BI gene
02/29/2000US6030777 Vector with dna sequence capable of coding for antisigma polypeptide which includes a multiple cloning site for heterologous genes; for direct selection of colonies with recombinant plasmid by loss of expression of toxic gene
02/29/2000US6030776 Parallel SELEX
02/29/2000US6030775 Determining allelic type of human major histocompatibility complex gene in tissue sample using consensus primer hybridizing to intron 1 or 3 with another primer hybridizing to other portion of gene, then evaluating amplified product
02/29/2000US6030774 Hybridization assay to detect presence of a polynucleotide analyte with specific sequences
02/29/2000US6030772 Neutralizing antibodies against HIV infection
02/29/2000US6030769 Strains of human immunodeficiency virus; for use as sensitive diagnositic agents and immunogenic compositions
02/29/2000US6030657 Labeling technique for countering product diversion and product counterfeiting
02/29/2000US6030621 Ginkgo biloba composition, method to prepare the same and uses thereof
02/29/2000US6030617 Use of growth differentiation factor-9 (GDF-9) to inhibit oocyte maturation
02/29/2000US6030581 Laboratory in a disk
02/29/2000US6030115 Monitoring the fluorescent intensity of a mixture of a sample and a probe which is labeled with a fluorescent intercalative dye and contains a base sequence complementary to a specific nucleic acid in the sample, when the temperature is varied
02/29/2000CA1340916C Method for enhancing production of secondary metabolites using clustered biosynthetic genes
02/28/2000CA2249037A1 Novel compounds
02/24/2000WO2000010013A2 Composition and methods for exposing antigenic epitopes on cultered microorganism
02/24/2000WO2000010009A1 Agarose format for mammalian cell based reporter assays
02/24/2000WO2000009761A1 Improved microbial catalyst for desulfurization of fossil fuels
02/24/2000WO2000009760A1 IDENTIFICATION OF A REGION OF THE MAJOR SURFACE GLYCOPROTEIN (MSG) GENE OF HUMAN $i(PNEUMOCYSTIS CARINII)
02/24/2000WO2000009759A1 Methods for identifying somatic changes in genomic sequences useful for cancer diagnosis and prognosis
02/24/2000WO2000009758A1 NOVEL AMPLICON IN THE 20q13 REGION OF HUMAN CHROMOSOME 20 AND USES THEREOF
02/24/2000WO2000009757A1 Optically characterizing polymers
02/24/2000WO2000009756A1 Adapter directed expression analysis
02/24/2000WO2000009755A2 Domain specific gene evolution
02/24/2000WO2000009754A2 HUMAN STEAROYL-CoA DESATURASE-RELATED COMPOSITIONS AND METHODS FOR TREATING SKIN DISORDERS
02/24/2000WO2000009753A1 Methods and systems for sequencing dna by distinguishing the decay times of fluorescent probes
02/24/2000WO2000009752A1 Cyp3a4 nfse variant and methods of use therefor
02/24/2000WO2000009751A1 Diagnostic methods using serial testing of polymorphic loci
02/24/2000WO2000009750A1 Compositons, kits, and methods for hydrodynamic stress-related regulation of gene expression
02/24/2000WO2000009749A1 Method of detecting a dna sequence, a dna sequence, a method of making a dna construct and the use thereof
02/24/2000WO2000009748A1 Microsatellite instability and disease
02/24/2000WO2000009747A1 Method for separating and characterising functions potentially present in a biological sample containing nucleic acids
02/24/2000WO2000009746A1 Vessel for blood sampling
02/24/2000WO2000009745A1 Primer-specific and mispair extension assay for identifying gene variation
02/24/2000WO2000009743A1 Artificial test soil
02/24/2000WO2000009742A1 Recovery of sublethally-injured microorganisms
02/24/2000WO2000009740A2 Method and apparatus for detecting viruses using primary and secondary biomarkers
02/24/2000WO2000009738A1 Rolling circle-based analysis of polynucleotide sequence
02/24/2000WO2000009727A2 Dna shuffling to produce herbicide selective crops
02/24/2000WO2000009716A1 Method for purifying proteins and/or biomolecule or protein complexes
02/24/2000WO2000009710A2 Compositions and methods for identifying mammalian malonyl coa decarboxylase inhibitors, agonists and antagonists
02/24/2000WO2000009709A2 Proteases and associated proteins
02/24/2000WO2000009707A1 Cellulase producing actinomycetes, cellulase produced therefrom and method of producing same
02/24/2000WO2000009704A1 Gene switch
02/24/2000WO2000009695A2 Drug targets in candida albicans
02/24/2000WO2000009693A2 Identification of the gene causing the mouse scurfy phenotype and its human ortholog
02/24/2000WO2000009691A2 Bpc-1: a secreted brain specific protein expressed and secreted by prostate and bladder cancer cells
02/24/2000WO2000009690A1 Extracellular adhesive proteins, exadh1 and exadh2
02/24/2000WO2000009689A2 A single gene encoding aortic-specific and striated-specific muscle cell isoforms, its regulatory sequences and uses thereof
02/24/2000WO2000009686A1 Gene
02/24/2000WO2000009684A1 NUCLEIC ACID CAPABLE OF BINDING SPECIFICALLY TO Ras TARGET PROTEIN
02/24/2000WO2000009683A1 Genes for detecting bacteria and detection method by using the same
02/24/2000WO2000009679A1 Method for obtaining in vitro recombined polynucleotide sequences, sequence banks and resulting sequences
02/24/2000WO2000009669A1 Human mesencephalon cell lines and methods of use therefor