Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
11/2003
11/13/2003US20030211582 Human DNA Ligase III
11/13/2003US20030211576 Comprises nucleotide sequences coding membrane protein for use in treatment of tumors and cell proliferative diseases; antiinflammatory agents
11/13/2003US20030211571 For stimulating release of tumor necrosis factor and/or cellular proliferation/differentiation of chrondrocytes by contacting blood with polypeptide; cancer diagnosis
11/13/2003US20030211570 Comprises nucleotide sequences coding membrane protein for use in treatment of tumors and cell proliferative diseases; antiinflammatory agents
11/13/2003US20030211569 Comprises nucleotide sequences coding membrane protein for use in treatment of tumors and cell proliferative diseases; antiinflammatory agents
11/13/2003US20030211568 Secreted and transmembrane polypeptides and nucleic acids encoding the same
11/13/2003US20030211563 Human testis specific serine/threonine kinase 1 & 2
11/13/2003US20030211561 Human oxalyl-CoA decarboxylase
11/13/2003US20030211559 Comprises composition for identifying therapeutic agents that inhibit proteolytic processing of amyloid precursor protein; treating nervous system disorders
11/13/2003US20030211552 Cyclic GMP dependent protien kinase as a chemotherapeutic target for antiprotozoal agents
11/13/2003US20030211546 Identifying bioactive agent/enzyme inhibitors capable of interfering with the binding of protein phosphatase 5 (PP5) to RAD protein; antitumor agents
11/13/2003US20030211540 Treatment of insulin resistance
11/13/2003US20030211524 Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
11/13/2003US20030211511 Nucleic acids and proteins with thioredoxin reductase activity
11/13/2003US20030211506 Comprises nucleotide sequences coding Bacillus endonuclease and modification methylase for propagating nucleotide sequences using strand displacement amplification
11/13/2003US20030211494 Recovering nucleotide sequences coding amylases, aminocyclases and/or amidohydrolases; diagnostic tools
11/13/2003US20030211490 Plants tolerant of environmental stress conditions, methods of generating same and novel polynucleotide sequence utilized thereby
11/13/2003US20030211176 Using plant extract; hot water extraction
11/13/2003US20030211127 Controlled dissolution crosslinked prote in crystals
11/13/2003US20030211094 High molecular weight derivatives of vitamin k-dependent polypeptides
11/13/2003US20030211093 Human kinases
11/13/2003US20030211092 Genetic engineering; gene expression; culture product
11/13/2003US20030211091 Secreted and transmembrane polypeptides and nucleic acids encoding the same
11/13/2003US20030211080 Congestive heart failure; monitoring gene expression; supplying adeno-associated viral vector
11/13/2003CA2485102A1 Recombinant glycosyltransferase fusion proteins
11/13/2003CA2485089A1 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
11/13/2003CA2485060A1 Method for producing multiple unsaturated fatty acids in plants
11/13/2003CA2484551A1 Smart pro-drugs of serine protease inhibitors
11/13/2003CA2484499A1 Short enzyme donor fragment
11/13/2003CA2484251A1 Materials and methods for inhibition of respiratory syncytial virus infection
11/13/2003CA2484244A1 Stable cytochrome p450 24 (cyp24) expressing cell line and methods and uses thereof
11/13/2003CA2484189A1 Methionine aminopeptidase-2 inhibitors and methods of use thereof
11/13/2003CA2483915A1 Vectors having both isoforms of b-hexosaminidase
11/13/2003CA2483891A1 Gene targeting using replicating dna molecules
11/13/2003CA2483478A1 Factor vii or viia polypeptide variants
11/13/2003CA2482879A1 Transgenic high tryptophan plants
11/13/2003CA2482860A1 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
11/13/2003CA2482789A1 Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (ctgf) as a unique means to both lower intraocular pressure and treatglaucomatous retinopathies/optic neuropathies
11/12/2003EP1361439A1 Screening for peptides inhibiting PP1c binding to Bcl-2, BCL-Xl and BCL-W proteins
11/12/2003EP1361433A2 Method for estimating therapeutic efficacy of tumor necrosis factor (TNF)
11/12/2003EP1361285A2 Protein kinase peptide substrate determination using peptide libraries
11/12/2003EP1361284A1 Process for generating sequence-specific proteases by directed evolution and use thereof
11/12/2003EP1361278A2 Process for the production of amino acids using phosphoglucose isomerases from coryneform bacteria
11/12/2003EP1361276A1 Pro-urokinase mutants
11/12/2003EP1361275A1 Cloned DNA polymerases from thermotoga neapolitana and mutants thereof
11/12/2003EP1361274A1 Polypeptide having alpha-isomaltosylglucosaccharide synthase activity
11/12/2003EP1361270A2 Disruption of the REDK gene
11/12/2003EP1361229A2 Use of Tyrosine Kinase (PYK2) to produce antibodies
11/12/2003EP1360965A1 Methods of treating diseases in association with decrease in the expression of aop-1 gene or aop-1 and remedies for the diseases
11/12/2003EP1360898A1 Joint utilization of the insulin gene and the glucokinase gene in the development of therapeutic approaches for diabetes mellitus
11/12/2003EP1360334A1 Methods of using mammalian rnase h and compositions thereof
11/12/2003EP1360309A2 Nucleic acid sequences to proteins involved in tocopherol synthesis
11/12/2003EP1360307A2 Chimeric polypeptides of serum albumin and uses related thereto
11/12/2003EP1360306A2 Dna sequence of the enzyme phospholipase a1 of ciliate tetrahymena, and the use of the same
11/12/2003EP1360304A2 Enzymes
11/12/2003EP1360302A2 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
11/12/2003EP1360301A2 Genes involved in isoprenoid compound production
11/12/2003EP1360299A2 The genome of a bifidobacterium
11/12/2003EP1360286A2 Characterization of the gsk-3beta protein and methods of use thereof
11/12/2003EP1360285A1 A method of preparing cross-linked enzyme aggregates
11/12/2003EP1360284A2 Recombinant proteinase k
11/12/2003EP1360283A2 Expression of recombinant proteinase k from i tritirachium album /i in yeast
11/12/2003EP1360282A2 Degradation and detection of tse infectivity
11/12/2003EP1360281A2 Regulation of human wee1-like serine/threonine protein kinase
11/12/2003EP1360280A2 Tissue transglutaminase
11/12/2003EP1360279A2 Novel form of the phgpx protein as a diagnostic marker for male infertility
11/12/2003EP1360278A2 Lipase variants
11/12/2003EP1360197A2 Histidine phosphatase interacting protein with 240kd
11/12/2003EP1360196A2 Improved method for production of secreted proteins in fungi
11/12/2003EP1359797A1 Human sphingosine-1-phosphate phosphatase
11/12/2003EP1084257B1 A STRAIN E.COLI JM83/pKP2 TRANSFORMED WITH A NOVEL PLASMID AND PHYTASE PRODUCED THEREFROM
11/12/2003EP1007624B1 Ds11 (kctc 0231bp), novel bacillus sp. strain and novel phytase produced by it
11/12/2003EP0975725B1 Detergent composition
11/12/2003EP0840742A4 Systematic evolution of ligands by exponential enrichment: chemi-selex
11/12/2003EP0773952B1 Interaction trap systems for detecting protein interactions
11/12/2003EP0767837B1 Increased production of beta-galactosidase in aspergillus oryzae
11/12/2003CN1455678A Methods of therapy with thrombin derived peptides
11/12/2003CN1454994A Affinity chromatography method of separating and purifying single-component earthworm plasminogen
11/12/2003CN1454993A Method of producing lipase by fermentation process
11/12/2003CN1454992A Algin lyase, and preparing method and use thereof
11/12/2003CN1127571C Permentative production of valuable compounds on industrial scale using chemically defined media
11/12/2003CN1127516C Novel polypeptides
11/12/2003CN1127510C Prodrugs of thrombin inhibitors
11/11/2003US6646184 Trichothecene-resistant transgenic plants
11/11/2003US6646182 Mre11 orthologue and uses thereof
11/11/2003US6646117 Having endoribonuclease activity; inactivates the viral capsid protein gene by cleavage
11/11/2003US6646006 Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
11/11/2003US6645999 Lactacystin analogs
11/11/2003US6645942 Implanting collagen matrix containing transduced subject-derived primary fibroblasts infected with recombinant retroviral vector; gene expression
11/11/2003US6645763 Immortalized bone marrow mesenchymal stem cell
11/11/2003US6645762 Synthases
11/11/2003US6645760 Negative strand RNA viral vector having autonomous replication capability
11/11/2003US6645754 Metabolically engineered lactic acid bacteria and their use
11/11/2003US6645753 Polynucleotides; antisense agents; MAP-kinases; nucleotide sequences; use of polypeptides to identify agents modulating signal transduction leading to cell proliferation, differen-tiation, survival and treatment of such conditions (cancer)
11/11/2003US6645751 Nucleic acid isolated from Tetrahymena which codes for a triterpenoid cyclase, its production, and use
11/11/2003US6645750 Polynucleotides encoding polypeptides having β-primeverosidase activity
11/11/2003US6645749 Nucleotide sequences coding polypeptide for use in the baking and detergents
11/11/2003US6645748 Mitosis; kinetochores; immunoassay; spindle; kits; Xenopus; use to demonstrate Centromere-Associated Protein-E (CENP-E) role in mitosis and identify modulators of CENP-E activity for therapeutic, diagnostic or bioagricultural applications
11/11/2003US6645747 Cis-prenyltransferases from plants
11/11/2003US6645746 Expression vector; transformants; E. coli; Candida; Bacillus; use of microorganisms to produce t-butyl(3R,5S)-6-chloro-3,5 -dihydroxyhexanoate, by enzymatic asymmetrical reduction, for drug, pesticide and HMG-CoA reductase inhibitor synthesis