Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
12/2003
12/18/2003US20030232035 Capable of expressing a heterologous sequence in target cells; vaccines
12/18/2003CA2493890A1 Methods for using adamts-12, an integrin and metalloprotease with thrombospondin motifs
12/18/2003CA2488558A1 Prevention and reduction of blood loss
12/18/2003CA2488388A1 Nicking endonucleases
12/18/2003CA2488328A1 Retrons for gene targeting
12/18/2003CA2487943A1 Methods of diagnosing & treating diabetes and insulin resistance
12/18/2003CA2487418A1 Metalloproteinase inhibitors
12/18/2003CA2487077A1 Isolated nucleic acid molecule encoding a novel centromere-associated motor protein, and uses thereof
12/18/2003CA2486362A1 Novel recombinant anticoagulant proteins
12/18/2003CA2480619A1 Novel oxidase
12/17/2003EP1371734A1 Method of deamidation of milk protein and method of denaturation of milk protein
12/17/2003EP1371732A1 Fused protein having beta 1,2-n-acetylglucosaminyltransferase ii activity and process for producing the same
12/17/2003EP1371731A1 Aminoketone asymmetric reductase and nucleic acid thereof
12/17/2003EP1371725A1 Novel aminopeptidase and its gene
12/17/2003EP1371663A1 Thrombin derivatives and process for producing the same, anhydrothrombin derivatives and process for producing the same, platelet agglutination-inducing compositions, method of inducing platelet agglutination, clinical test reagents, clinical test method, thrombosis inhibitors, adsorbent and process
12/17/2003EP1371367A1 Use of naaladase inhibitors for the manufacture of a medicament for the treatment of certain diseases
12/17/2003EP1370696A2 Expression profiles and methods of use
12/17/2003EP1370682A2 Assay for identifying inhibitors of the rna dependent rna polymerase (ns5b) of hcv
12/17/2003EP1370681A2 Methods using fluorescence energy transfer probes for detecting cleavage of nucleic acids
12/17/2003EP1370674A2 Enzymes having alpha amylase activity and methods of use thereof
12/17/2003EP1370670A2 Processes for enhanced production of pantothenate
12/17/2003EP1370663A2 Microbiological method for producing l-carnitine
12/17/2003EP1370662A2 Polypeptide sequences of drug metabolizing enzymes and polynucleotide sequences coding therefor
12/17/2003EP1370659A2 Proteins, polynucleotides encoding them and methods of using the same
12/17/2003EP1370650A2 Novel genes for conditional cell ablation
12/17/2003EP1370649A1 Protein c variants
12/17/2003EP1370648A2 Alpha-amylase mutants with altered properties
12/17/2003EP1370647A2 A dna molecule encoding a variant paraoxonase and uses thereof
12/17/2003EP1370646A2 Purified porcine kidney l-fucose kinase
12/17/2003EP1370645A2 Adenylyl and guanylyl cyclases
12/17/2003EP1370580A2 A new essential downstream component of the wingless signalling pathway
12/17/2003EP1370578A1 Gene cluster for rabelomycin biosynthesis and its use to generate compounds for drug screening
12/17/2003EP1370573A2 Low molecular serine protease inhibitors comprising polyhydroxy-alkyl and polyhydroxy-cycloalkyl radicals
12/17/2003EP1370298A1 Elongated and multiple spacers in activatible prodrugs
12/17/2003EP1370132A2 Use of telomerase reverse transcriptase to create homozygous knockout animals
12/17/2003EP1109805B1 Inhibitors of bacterial nad synthetase
12/17/2003EP1102781B1 New cofactors for methyltransferases
12/17/2003EP0917580B1 DEFORMYLATION OF f-MET PEPTIDES IN BACTERIAL EXPRESSION SYSTEMS
12/17/2003EP0826054B1 Expression of glycosyltransferase in aspergillus
12/17/2003EP0763101B1 Nucleic acid sequences and expression systems for heparinase iii derived from flavobacterium heparinum
12/17/2003EP0672131B1 A novel cell cycle control protein
12/17/2003CN1131315C Prodn. of trehalos in plant
12/17/2003CN1131306C Protease form amycolata
12/17/2003CN1131305C Trichoderma chitinase adn gene for expressing it
12/16/2003US6664445 Plant amino acid biosynthetic enzymes
12/16/2003US6664444 1-SST (sucrose:sucrose 1-fructosyl-transferase) enzyme encoding cDNA sequence; transformation; highly linear polysaccharide chains; use in food, feed and beverages
12/16/2003US6664387 Expression cassette and plasmid for strong constitutive gene expression and the use thereof
12/16/2003US6664383 Polypeptides, cDNA encoding the same and utilization thereof
12/16/2003US6664376 Chimeric polypeptide molecules
12/16/2003US6664370 Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated
12/16/2003US6664247 Pyrazole compounds useful as protein kinase inhibitors
12/16/2003US6664108 Mobilization of viral genomes from T-DNA using site-specific recombination systems
12/16/2003US6664105 Polynucleotide encoding a polypeptide having heparanase activity and expression of same in genetically modified cells
12/16/2003US6664097 Polynucleotide encoding a Lactobacillus gasseri beta-glucuronidase polypeptide
12/16/2003US6664093 Polypeptide having amino acid sequence 2; targets, enzyme modulators, identification of therapeutic proteins
12/16/2003US6664092 Nucleic acid sequences; amino acid sequences; vectors; host cells; genetic engineering; Aspergillus oryzae; use in the production of protein hydrolysates having desirable organoleptic properties and high degrees of hydrolysis
12/16/2003US6664091 53010, a human carboxylesterase family member and uses thereof
12/16/2003US6664090 Carboxylesterase nucleic acid molecules, proteins and uses thereof
12/16/2003US6664089 Nucleotide sequences coding enzymatic proteins; for use in the treatment of cell proliferation and differention disorders; antiproliferative agents
12/16/2003US6664088 Production of vanillin
12/16/2003US6664087 Isolated human kinase proteins
12/16/2003US6664086 Polypeptide encoded by open reading frame in nucleotide sequence 3 or 5 of sequences that degenerate to 3 or 5
12/16/2003US6664085 Peptide for use in the diagnosis and treatmentnt of inflammation, cancer, arteriosclerosis and psoriasis
12/16/2003US6664084 Isolated nucleic acid molecules encoding human glucuronyltransferase proteins, and related products and processes
12/16/2003US6664082 Microorganism belonging to the genus Gluconobacter, which has an engineered gene for the biological activity of reducing L-sorbose which is more than 90% non- functional in developing the said biological activity.
12/16/2003US6664072 Kits for screening for modulators of the motor protein HsKip3b
12/16/2003US6664051 Fixation of nucleotide derivatives to solid carrier
12/16/2003US6664039 Having very long chain fatty acid coA synthetase activity; identifying a compound that inhibits the thioesterification activity of VLCFA coA-syn
12/16/2003US6663906 Expression of fructose 1,6 bisphosphate aldolase in transgenic plants
12/16/2003US6663903 To improve the properties of dough and/or baked products
12/16/2003CA2096604C Protein c derivatives
12/16/2003CA2068614C Esterase genes, esterase, recombinant plasmids and transformants containing the recombinant plasmid and methods of producing optically active carboxylic acids and their enantiomeric esters using said transformants
12/11/2003WO2003102213A2 Error-prone dna polymerase i mutants and methods for targeted random mutagenesis in continuous culture using error-prone dna polymerase i mutants
12/11/2003WO2003102209A2 Alternatively spliced isoforms of human hmg co-a reductase
12/11/2003WO2003102201A2 Methods and materials for the production of d-lactic acid in yeast
12/11/2003WO2003102200A2 Fermentation process using specific oxygen uptake rates as a process control
12/11/2003WO2003102195A1 Protein hydrolysate rich in tripeptides
12/11/2003WO2003102194A1 Chondroitin synthetase and dna coding for the enzyme
12/11/2003WO2003102193A1 Chondroitin synthetase and nucleic acid coding for the enzyme
12/11/2003WO2003102192A1 Methods of purification of cytochrome p450 proteins and of their crystallizing
12/11/2003WO2003102190A2 Bacterial polypeptides involved in viability
12/11/2003WO2003102175A1 Regulation of human adenylate cyclase, type ii
12/11/2003WO2003102174A2 Modified phytases
12/11/2003WO2003102169A1 Anaerobe targeted enzyme-mediated prodrug therapy
12/11/2003WO2003102163A2 Methods of diagnosing and treating diabetes and insulin resistance
12/11/2003WO2003102160A2 Rationally designed polysaccharide lyases derived from chondroitinase b
12/11/2003WO2003102154A2 Improved receptor detection
12/11/2003WO2003102152A2 Methods and materials for the production of lactic acid in yeast
12/11/2003WO2003102148A2 Human prolactin antagonist-angiogenesis inhibitor fusion proteins
12/11/2003WO2003102147A2 Mutants of gad65 and ian5 relating to diabetes
12/11/2003WO2003102143A2 HUMAN COACTIVATOR-ASSOCIATED ARGININE METHYLTRANSFERASE 1 (hCARM1)
12/11/2003WO2003102142A2 Arrays identifying genomic and proteomic biomarkers for cystic fibrosis
12/11/2003WO2003102138A2 Elongase genes and uses thereof
12/11/2003WO2003102135A2 Control sequences of the human corin gene
12/11/2003WO2003102128A1 Maize nucleotide sequence coding for a protein with transglutaminase activity and use thereof
12/11/2003WO2003102031A1 Proteins and methods useful for assessing risk of cardiovascular disease
12/11/2003WO2003102029A1 Sut-2 and sut-3 genes, proteins and assays for inhibitors of lymphocyte adhesion
12/11/2003WO2003102025A1 Protein inducing cell death of helicobacter pylori
12/11/2003WO2003102016A2 Amyloid peptide inactivating enzyme to treat alzheimer's disease
12/11/2003WO2003101386A2 Kinase suppressor of ras inactivation for therapy of ras mediated tumorigenesis