Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
04/2004
04/08/2004CA2496761A1 Porcine animals lacking any expression of functional alpha 1,3 galactosyltransferase
04/08/2004CA2403025A1 Enzymes with lipase/acyltransferase activity
04/07/2004EP1405922A2 Substrates for beta-lactamase and uses thereof
04/07/2004EP1405914A1 Nucleic acid sequences and expression systems for heparinase II and heparinase III derived from flavobacterium heparinum
04/07/2004EP1405912A1 Genetically modified ecarin and process for producing the same
04/07/2004EP1405911A1 Interaction trap systems for detecting protein interactions
04/07/2004EP1405910A1 Process for producing human thrombin by gene modification technique
04/07/2004EP1405907A2 Conjugate of a tissue non-specific alkaline phosphatase and dextran, process for its production and use thereof
04/07/2004EP1405668A1 Novel separation agent for separating optical isomer and method for preparation thereof
04/07/2004EP1405558A1 Method of elevating glutamic acid content in plant and plants having elevated glutamic acid content
04/07/2004EP1404865A2 System for discovery of agents that block yersinia pestis and pseudomonas aeruginosa dna replication
04/07/2004EP1404864A2 Regulation of neuronal function through metabotropic glutamate receptor signaling pathways
04/07/2004EP1404862A1 Thermostable proteinases from thermophilic bacteria
04/07/2004EP1404858A2 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
04/07/2004EP1404857A2 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
04/07/2004EP1404856A2 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
04/07/2004EP1404844A2 Process for the preparation of 2,4-dideoxyhexoses and 2,4,6-trideoxyhexoses
04/07/2004EP1404843A2 Regulation of human nek-like serine/threonine protein kinase
04/07/2004EP1404841A2 Cyp1b1 nucleic acids and methods of use
04/07/2004EP1404839A2 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
04/07/2004EP1404838A2 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family with enhanced fba expression
04/07/2004EP1404837A2 Process for the preparation of l-amino acids using strains of the enterobacterialceae family with enhanced pts-g expression
04/07/2004EP1404836A2 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
04/07/2004EP1404835A2 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family with enhanced mop-b expression
04/07/2004EP1404829A1 Novel aminopeptidase derived from bacillus licheniformis, gene encoding the aminopeptidase, expression vector containing the gene, transformant and method for preparation thereof
04/07/2004EP1404828A1 A crystallised catalytic domain of matrix metalloproteinase 9 (mmp9) and the use of its three dimensional structure to design mmp9 modulators
04/07/2004EP1404827A2 Lipolytic enzyme genes
04/07/2004EP1404826A2 Isolated human phosphatase proteins, nucleic acid molecules encoding human phosphatase proteins, and uses thereof
04/07/2004EP1404825A2 A WALK-THROUGH TECHNIQUE FOR i IN VITRO /i RECOMBINATION OF POLYNUCLEOTIDE SEQUENCES
04/07/2004EP1404824A2 Novel dna polymerases having amino acid substitutions and homologs thereof
04/07/2004EP1404823A2 Method for determining the genetic predisposition of a mammal for its milk fat content and/or for its intramuscular fat content
04/07/2004EP1404822A2 Isolated human enzyme proteins, nucleic acid molecules encoding human enzyme proteins, and uses thereof
04/07/2004EP1404821A2 Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
04/07/2004EP1404820A2 50365, a hexokinase family member and uses therefor
04/07/2004EP1404718A2 Inhibitors of memapsin 2 and use thereof
04/07/2004EP1404706A2 Mycobacterial antigens expressed during latency
04/07/2004EP1404364A1 Sphingosine kinase interacts with traf2 and modulates tumor necrosis factor-induced cellular activity
04/07/2004EP1404362A2 Signal-1/signal-2 bifunctional peptide inhibitors
04/07/2004EP1404350A2 Proteins associated with cell growth, differentiation, and death
04/07/2004EP1124843B1 Low allergenic protein variants
04/07/2004EP1015622B1 Practical in vitro sialylation of recombinant glycoproteins
04/07/2004EP0979277B1 Novel human tumour suppressor gene
04/07/2004EP0787148B1 Al-1 neurotrophic factor, a ligand for an eph-related tyrosine kinase receptor
04/07/2004EP0587791B1 Enhancement of expression by gene targeting in endogenous retrovirus-like sequences
04/07/2004EP0559884B2 Viral recombinant vectors for expression in muscle cells
04/07/2004CN1488000A Method for purification of soluble SSAO
04/07/2004CN1487998A Gene encoding acetolactic acid sy nthase gene
04/07/2004CN1487997A Gene HD3A inducing flowering of plant and utilization thereof
04/07/2004CN1487995A Low-Lipoxygenase 1 barley
04/07/2004CN1487933A Pyrazole compounds useful as protein kinase inhibitors
04/07/2004CN1487837A Novel mixtures of microbial enzymes
04/07/2004CN1487080A Alkaline protease
04/07/2004CN1144910C Multi-component system for the enzyme-catalysed oxidation of substrates and method for enzyme-catalysed oxidation
04/07/2004CN1144876C Process for producing cis-3-hydroxy-L-proline
04/07/2004CN1144874C Production of enzymatically active recombinant carboxypeptidase B
04/06/2004US6717033 Transforming plant cells to alter the metabolic state
04/06/2004US6717030 Diploid animal cell for use in the treatment of drug addiction, epilepsey, withdrawal syndrome and muscle spasm
04/06/2004US6717006 Reacting aldehyde or ketone with hydrocyanic acid stirred aqueous-solvent emulsion; reduced enzyme and time requirements
04/06/2004US6716960 Mch3, a novel apoptotic protease, nucleic acids encoding and methods of use
04/06/2004US6716827 Complexes for immobilizing isothiocyanate natural precursors in cyclodextrins, preparation and use
04/06/2004US6716824 Antitumor
04/06/2004US6716818 Caspase inhibitors and the use thereof
04/06/2004US6716625 Histidine kinases of Aspergillus and other fungal species, related compositions, and methods of use
04/06/2004US6716624 GSK3 polypeptides
04/06/2004US6716617 Fermentation method with continuous mass cultivation of ciliates (protozoa) for producing biogenous valuable substances
04/06/2004US6716616 Nucleotides that encode proteins that share structural similarity with animal kinases, and more particularly serine/threonine protein kinases.
04/06/2004US6716614 Polynucleotides encoding proteins that share sequence similarity with human calcium dependent proteases, specifically calpains.
04/06/2004US6716613 Metalloprotease having aggrecanase activity
04/06/2004US6716612 Modifying the branching degree of amylopectin synthesized in plants,
04/06/2004US6716609 Enzymatic polypeptide for use in the generation of 2-pyrone-4,6-dicarboxylic acid
04/06/2004US6716608 Artificial chromosome
04/06/2004US6716604 Calcium/calmodulin-dependent protein kinase peptide for treatment of arteriosclerosis and psoriasis; antiinflammatory/anticarcinogeneic agents
04/06/2004US6716583 Methods of producing nucleic acid ligands
04/06/2004US6716575 Diagnosis and treatment of AUR1 and/or AUR2 related disorders
04/06/2004US6716474 Expression of fructose 1,6 bisphosphate aldolase in transgenic plants
04/06/2004US6716430 Moderating immunology response
04/06/2004CA2257122C Method of activating denatured protein
04/06/2004CA2085232C Xylanase production
04/06/2004CA2036592C Therapeutic agent for diabetic gangrene
04/01/2004WO2004027378A2 Luminescence-based methods and probes for measuring cytochrome p450 activity
04/01/2004WO2004027075A2 Chemoenzymatic methods for the synthesis of statins and stain intermediates
04/01/2004WO2004027072A2 Method for making recombinant proteins
04/01/2004WO2004027069A1 Transgenic expression cassettes for the expression of nucleic acids in plant blooms
04/01/2004WO2004027067A2 Methods for increasing the production of a recombinant polypeptide from a host cell
04/01/2004WO2004027065A2 Enone reductase gene and microbial production of levodione
04/01/2004WO2004027055A1 Novel carbonyl reductase, gene thereof and method of using the same
04/01/2004WO2004027054A1 Thermostable rna ligase from thermus phage
04/01/2004WO2004027032A2 Stearoyl coa desaturase transgenic non-human animals
04/01/2004WO2004027022A2 Enzymes
04/01/2004WO2004027020A2 Identification of a phage associated lytic enzyme to rapidly and specifically detect and kill bacillus anthracis
04/01/2004WO2004027018A2 Inducible focal adhesion kinase cell assay
04/01/2004WO2004026898A1 Peptide complexes containing phospholipase d
04/01/2004WO2004026407A1 Use of inhibitors of compounds involved in the jun kinase (jnk) biochemical cellular pathway for the treatment or diagnosis of liposarcomas
04/01/2004WO2004026285A2 Compositions and methods for treating heart disease
04/01/2004WO2004026254A2 Methods for the preparation, isolation and purification of epothilone b, and x-ray crystal structures of epothilone b
04/01/2004WO2004009803A3 Regulation of human hepsin
04/01/2004WO2004005473A3 Hcv fusion proteins with modified ns3 domains
04/01/2004WO2003106630A3 Methods and compositions relating to polypeptides with rnase iii domains that mediate rna interference
04/01/2004WO2003097825A3 Novel phospholipases and uses thereof
04/01/2004WO2003096022A3 Screening for peptides inhibiting pp1c binding to bcl-2, bcl-xl and bcl-w proteins