Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
04/2004
04/22/2004US20040078840 Chimeric isoprenoid synthases and uses thereof
04/22/2004US20040078838 Transgenic plant cells with reduced citrate synthase activity in comparison to wild type cells
04/22/2004US20040078836 Diacylglycerol O-Acyltransferase
04/22/2004US20040078147 Crystal structure of ACPS/ACP complex, solution structure of B.subtilis ACP, and uses thereof
04/22/2004US20040077581 Long chain fatty acid coA synthetase activity; polynucleotide encoding amino acid sequence 2
04/22/2004US20040077572 Polynucleotide or complement comprising nucleic acid sequence flanked by first and second inverted repeats
04/22/2004US20040077069 Method for the production of a heterologous protein by a fungus
04/22/2004US20040077066 Purified active HCV NS2/3 protease
04/22/2004US20040077065 Three dimensional coordinates of HPTPbeta
04/22/2004US20040077064 Identification and isolation of novel DNA and to the recombinant production of novel polypeptides
04/22/2004US20040077063 Comprises contacting a terpene analog having a terminal methyl group, for example limonene, with a microbial cell which is capable of expressing a monooxygenase capable of terminal hydroxylation of an n-alkane
04/22/2004US20040077049 For preventing, ameliorating, disorders or diseases including cancer, peripheral and central nervous system disorders, genitourinary disorders, cardiovascular disorders, and Chronic obstructive pulmonary (or airways) disease (COPD)
04/22/2004US20040077048 Used in the diagnosis, treatment, and prevention of gastrointestinal, cardiovascular, autoimmune/ inflammatory, cell proliferative, developmental, epithelial, neurological, and reproductive disorders
04/22/2004US20040077046 Histone deacetylase-related gene and protein
04/22/2004US20040077044 Nucleic acid and amino acid sequences of kinases and phosphatases and use of these sequences in the diagnosis, treatment, and prevention of cardiovascular diseases, immune system disorders, neurological disorders, cancer
04/22/2004US20040077042 Cell line expressing mutated human tissue-type plasminogen activator, the constructing strategy thereof and method of preparing expressed protein
04/22/2004US20040077040 Incorporation into a vector and expressing of the SBAmyB or SBAmyC gene of the sugar beet and recovering the product of the expressed gene
04/22/2004US20040077037 Regiospecific modification of peptides and proteins with probes and reporter molecules using peptidases in combination with a non-amino acid- like or non-peptide-like substrate mimetic
04/22/2004US20040077035 Mutated penicillin expandase and process for preparing 7-ADCA using the same
04/22/2004US20040077034 Mutated penicillin expandase and process for preparing 7-ADCA using the same
04/22/2004US20040077031 Using the manganese form of the enzyme and therefore, the advantage of identifying potent inhibitors that might not show activity in cellular systems because the wrong metal cofactor is used
04/22/2004US20040077022 Modified peptides as therapeutic agents
04/22/2004US20040077016 The bacteria are good research materials for investigating the interrelation between enzyme structures and functions since they are stable at extreme pH, crystallize easily and are easy- to-handle
04/22/2004US20040077013 DNA constructs, host cells and production methods for the expression and recovery of polypeptides altered to have glycosylation sites added or deleted; employ a DNA segment corresponding to a mammalian tissue plasminogen activator
04/22/2004US20040077012 Thermostable DNA polymerases that can serve as chromosomal replicases and are derived from thermophilic bacteria
04/22/2004US20040077011 Novel human gene relating to respiratory diseases and obesity
04/22/2004US20040077010 32142, 21481, 25964, 21686, novel dehydrogenase molecules and uses therefor
04/22/2004US20040077009 Human cyclin-dependent kinase (hPNQALRE)
04/22/2004US20040077008 Method and compositions for reversible inhibition of thermostable polymerases
04/22/2004US20040077005 Novel topoisomerase IV, corresponding nucleotide sequences and uses thereof
04/22/2004US20040076997 Determining the risk of metastasis of a breast or colon tumor, which involve determining whether a tissue sample from a tumor expresses a polypeptide encoded by a gene SEQ ID NOS:1-18
04/22/2004US20040076993 Novel calcium-independent phospholipases a2, genes thereof and promoter of the same
04/22/2004US20040076982 3-hydroxypropionic acid and other organic compounds
04/22/2004US20040076977 Marker assisted selection of bovine for improved milk production using diacylglycerol acyltransferase gene dgat1
04/22/2004US20040076967 Novel human proteins, polynucleotides encoding them and methods of using the same
04/22/2004US20040076958 Methods and compositions for the treatment of Alzheimer's disease and other neurodegenerative disorders
04/22/2004US20040076949 Methods for identifying inhibitors of helicase activity from hepatitis C virus
04/22/2004US20040076624 Bandage composition containing phage associated lytic enzymes useful for treating dermatological infections
04/22/2004US20040076616 A lytic enzyme is produced by a bacteria being infected with a bacteriophage specific
04/22/2004US20040076612 For drug screening hepatitis C virus drugs
04/22/2004DE10247147A1 Production of D-mannitol, useful e.g. as sweetener and plasma extender, by culturing organisms that express mannitol-2-dehydrogenase and where substrate is introduced by a non-phosphorylating pathway
04/22/2004CA2501941A1 Secreted acid phosphatase (sapm) is present only in pathogenic mycobacteria and expressed selectively at acidic ph
04/22/2004CA2501752A1 Compositions, organisms and methodologies employing a novel human kinase
04/22/2004CA2501645A1 Proteases, nucleic acids encoding them and methods for making and using them
04/22/2004CA2501635A1 Method of purifying lantibiotics
04/22/2004CA2501581A1 Recombinant catalytic polypeptides and their uses
04/22/2004CA2501445A1 Polypeptides involved in spiramycin biosynthesis, nucleotide sequences encoding said polypeptides and uses thereof
04/22/2004CA2501391A1 Method and microorganism for the production of d-mannitol
04/22/2004CA2501208A1 Decomposition and modification of silicate and silicone by silase and use of the reversible enzyme
04/22/2004CA2500741A1 Glucose transport mutants for production of biomaterial
04/22/2004CA2500592A1 Compositions, organisms and methodologies employing a novel human kinase
04/21/2004EP1411128A1 Recombinant viral and non-viral vectors containing the human urokinase plasminogen activator gene and its utilization in the treatment of various types of hepatic, renal, pulmonary, pancreatic and cardiac fibrosis and hypertrophic scars
04/21/2004EP1411126A1 Nitrilase and encoding polynucleotide
04/21/2004EP1411125A1 Materials and methods for the alteration of enzyme and acetyl CoA levels in plants
04/21/2004EP1411124A2 Human cancer antigen of tyrosinase-related protein 1 and 2 and genes encoding same
04/21/2004EP1411116A1 PEPTIDE SYNTHASE GENE, PEPTIDE SYNTHASE AND PROCESS FOR PRODUCING DIPEPTIDE
04/21/2004EP1411062A1 Process for producing dipeptide,peptide synthase to be used therein and process for producing peptide synthase
04/21/2004EP1411060A1 PROCESS FOR PRODUCING DIPEPTIDE, L−AMINO ACID AMIDE HYDROLASE TO BE USED THEREIN AND PROCESS FOR PRODUCING L−AMINO ACID AMIDE HYDROLASE
04/21/2004EP1410038A2 Assays for identifying modulators of rhomboid polypeptides
04/21/2004EP1409718A2 Canine toxicity genes
04/21/2004EP1409715A2 Methods and materials relating to neurotrimin-like polypeptides and polynucleotides
04/21/2004EP1409714A2 Methods and systems for identifying kinases, phosphatases and substrates thereof
04/21/2004EP1409708A2 Glucans and glucansucrases derived from lactic acid bacteria
04/21/2004EP1409705A1 A process for the production of an inhibitor of human platelet aggregation and soybean lipoxygenase
04/21/2004EP1409696A2 Identification and characterization of plant genes
04/21/2004EP1409695A2 Expression system for recombinant proteins
04/21/2004EP1409691A2 Stereoselective preparation of cyclic l-amino acids
04/21/2004EP1409690A2 Human endothelin converting enzyme-like proteins and polynucleotides encoding the same
04/21/2004EP1409689A2 A lactococcus gene, the amylolytic enzyme it encodes and its application
04/21/2004EP1409688A2 Nucleic acid sequences encoding enantioselective amidases
04/21/2004EP1409687A2 22244 and 8701, human dehydrogenases and uses thereof
04/21/2004EP1409685A1 Proline-rich extensin-like receptor kinases
04/21/2004EP1409667A2 Process for preparing variant polynucleotides
04/21/2004EP1409666A2 Process for preparing variant polynucleotides
04/21/2004EP1409665A2 Method to generate non virulent microorganisms from pathogenic ones trough permanent genetic modification of their biological membrane for vaccine production
04/21/2004EP1409664A2 Yeast alpha-amylase promoter and uses thereof
04/21/2004EP1409662A1 Allene oxide synthase and divinyl ether synthase from the cyp74-enzyme family isolated out of physcomitrella patens, the nucleotide sequences that code these synthases, and method for producing pathogen-resistant plants
04/21/2004EP1409661A2 Hdac9 polypeptides and polynucleotides and uses thereof
04/21/2004EP1409660A2 Crystal structure of beta-site app cleaving enzyme (bace) and use thereof
04/21/2004EP1409659A2 Subtilase variants
04/21/2004EP1409658A2 Aggrecanase molecules
04/21/2004EP1409657A2 Isolated human kinase proteins, their encoding nucleic acid molecules, and uses thereof
04/21/2004EP1409654A1 Immunological control of beta-amyloid levels in vivo
04/21/2004EP1409652A2 Immortalized preosteoblasts and method for their production
04/21/2004EP1409641A2 Engineering fungi for the utilisation of l-arabinose
04/21/2004EP1409546A2 Protease inhibitor conjugates and antibodies useful in immunoassay
04/21/2004EP1409538A1 Process for obtaining growth factor (tgf-beta and igf-1), lactoperoxidase and immunoglobulins preparations from milk products having low mutual cross-contamination
04/21/2004EP1409529A2 Recombinant light chains of botulinum neurotoxins and light chain fusion proteins for use in research and clinical therapy
04/21/2004EP1409514A1 Chimeric histone acetyltransferase polypeptides
04/21/2004EP1409008A1 Use of the disintegrin domain of an adamalysin as anti-angiogenic, anti-invasive and anti-metastatic agent
04/21/2004EP1408984A2 Organo-phosphorous compounds for activating gamma/delta t cells
04/21/2004EP1408908A2 Compositions and methods for inhibition of cancer invasion and angiogenesis
04/21/2004EP1242818B1 Method to evaluate the sensitivity of hiv variants to drugs able to inhibit the hiv protease
04/21/2004EP1242603B1 Vectors and method for producing recombinant proteins in fungi
04/21/2004EP1212331B1 28-epirapalogs
04/21/2004EP1100310A4 Plants, seeds and oils having an elevated total monounsaturated fatty acid content
04/21/2004EP0972071A4 Protease inhibitor assay
04/21/2004CN1491282A Process for producing prenyl alcohol
04/21/2004CN1491281A Neurotonin and use thereof
04/21/2004CN1491279A Process for extraction of Beta-amylase