Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
02/2005
02/22/2005US6858411 Recombinant nucleic acids that encode epothilone polyketide synthase (PKS) are used to express recombinant PKS genes in host cells to produce epothilone derivatives/polyketides; used as cancer drugs, fungicides and immunosuppressants
02/22/2005US6858408 Genetically engineered expression vector coding enzymatic polypeptide for use in laundering detergents, textile treatment and paper processing
02/22/2005US6858402 System for discovering and producing polypeptides that cause TNF receptor shedding
02/22/2005US6858390 Aptamers containing sequences of nucleic acid or nucleic acid analogues bound homologously, or in novel complexes
02/22/2005US6858383 Compositions and methods for the treatment and prevention of cardiovascular diseases and disorders, and for identifying agents therapeutic therefor
02/22/2005US6858234 Extracting enzyme inhibitors from wheat flour or gluten for treating hyperglycemia, diabetes, hyperlipemia and arteriosclerosis
02/22/2005US6858213 Mycobacterial sulfation pathway proteins and methods of use thereof
02/22/2005US6858207 Methods and materials relating to novel CD39-like polypeptides
02/22/2005US6858206 Methods for treating diseases caused by deficiencies of recombinant alpha-L-iduronidase
02/22/2005CA2271232C Modified protein c and methods of use thereof
02/22/2005CA2184581C Improved dnase liquid solutions
02/22/2005CA2129039C Tri-substituted phenyl derivatives as phosphodiesterase inhibitors
02/22/2005CA2083243C Process for the production of a virus-free concentrate of thrombin
02/20/2005CA2477991A1 Stabilizing agent and blocking agent
02/17/2005WO2005015205A2 Use of sap
02/17/2005WO2005015154A2 Autocatalysis/yeast two-hybrid assay
02/17/2005WO2005014834A1 Fatty acid biosynthesis 3
02/17/2005WO2005014833A1 Fatty acid biosynthesis 1
02/17/2005WO2005014831A1 Fatty acid biosynthesis 2
02/17/2005WO2005014821A1 Cephalosporin c acylase mutant and method for preparing 7-aca using same
02/17/2005WO2005014820A1 5-enolpyruvyl-3-phosphoshikimate synthase of high glyphosate-bioresistance and coding sequence
02/17/2005WO2005014804A2 Ubiquitin-specific protease
02/17/2005WO2005014794A2 Generation of low phytate plants by molecular disruption of inositol polyphosphate kinases
02/17/2005WO2005014791A2 Methods and compositions for targeted cleavage and recombination
02/17/2005WO2005014790A2 Polypeptides having oxaloecetate hydrolase activity and polynucleotides encoding same
02/17/2005WO2005014788A2 Tssk4: a human testis specific serine/threonine kinase
02/17/2005WO2005014779A2 Cyclodextrin affinity purification
02/17/2005WO2005014607A2 Antisense modulation of stearoyl-coa desaturase expression
02/17/2005WO2005014570A1 CELLS AND METHOD FOR THE FERMENTATIVE PRODUCTION OF R-α-LIPOIC ACID
02/17/2005WO2005013675A1 OBTUSIFOLIOL 14a- DEMETHYLASE
02/17/2005WO2004108763A3 Mutants of the factor vii epidermal growth factor domain
02/17/2005WO2004097009A3 METHOD TO IDENTIFY AGENTS THAT ACTIVATE OR INHIBIT IKKi
02/17/2005WO2004083440A8 Modified ppase expression in sugar beet
02/17/2005WO2004081189A9 Multimodality imaging of reporter gene expression using a novel fusion vector in living cells and organisms
02/17/2005WO2004067548B1 Chemically modified metabolites of regulatory peptides and methods of producing and using same
02/17/2005WO2004042006A3 Amylases, nucleic acids encoding them and methods for making and using them
02/17/2005WO2004033471A3 Glucose transport mutants for production of biomaterial
02/17/2005WO2004014937A3 Thrombin peptide derivatives
02/17/2005WO2003091431A8 Methylotroph producing mammalian type sugar chain
02/17/2005WO2003034813A3 Synthetic herbicide resistance gene
02/17/2005WO2003025131A3 Protein modification and maintenance molecules
02/17/2005WO2003004681A3 Nucleic acid molecules encoding a transmembrane serine protease 20, the encoded polypeptides and methods based thereon
02/17/2005WO2002074913A3 Nucleic acid-associated proteins
02/17/2005US20050039234 Expression vector comprising nucleotide sequences coding desaturase for use in increasing/decreasing palmitoleic acid and/or vaccenic acid concentrations in seed
02/17/2005US20050039233 High oleic acid Brassica juncea
02/17/2005US20050039231 Method for selecting transformed plant cells using ethionine and cystathionine gamma synthase as the selection agent and marker gene
02/17/2005US20050039221 Phenotypic effects of ubiquinone deficiencies and methods of screening thereof
02/17/2005US20050038255 Stereoselective preparation of cyclic l-amino acids
02/17/2005US20050038086 Epothilone derivatives and methods for making and using the same
02/17/2005US20050038023 Inhibitors of glycogen synthase kinase-3 (gsk-3) and aurora-2, both serine/threonine protein kinases; for treating diseases such as cancer, diabetes and alzheimer's disease
02/17/2005US20050038019 Hydroxy substituted amides for the treatment of alzheimer's disease
02/17/2005US20050037964 Activated protein C variants with normal cytoprotective activity but reduced anticoagulant activity
02/17/2005US20050037478 Crystal structure of glutamate racemase (MurI)
02/17/2005US20050037476 Modified Wee1, crystals of peptide: inhibitor complexes containing such modified Wee1, and methods of use thereof
02/17/2005US20050037474 Method for controlling the yield and purity of proteinase inhibitor II during extraction
02/17/2005US20050037473 transformed E. coli comprises a polyhydroxyalkanoate (PHA) synthase gene of Pseudomonas species; producing PHA using a microorganism transformed with a recombinant vector containing the maoC gene and a recombinant vector containing a PHA synthase gene
02/17/2005US20050037462 Expression vector comprising nucleotide sequences coding g protein for use in generating immunoglobulins for use in prevention, treatment and diagnosis of cell proliferative disorders
02/17/2005US20050037459 Variant humicola grisea CBH1.1
02/17/2005US20050037458 Secreted and transmembrane polypeptides and nucleic acids encoding the same
02/17/2005US20050037454 Expression vector comprising nuclelotide sequences coding osteoblast protein for use in diagnosis, prevention and treatment of osteoporosis and bone resorption disorders
02/17/2005US20050037453 Peptide-forming enzyme gene, peptide-forming enzyme, and peptide producing method
02/17/2005US20050037450 Novel targets for lithium therapy
02/17/2005US20050037446 Protein kinase binding modulator for use in treatment and prevention of cardiovascular, cell proliferative, neurodegenerative and bone disorders
02/17/2005US20050037435 Generating new compounds without predetermining a desired structure or composition; rational drug design
02/17/2005US20050037432 Macroglobulin peptides for use as diagnostic indicator of osteoarthritis, bone and tissue disorders
02/17/2005US20050037412 Thermostable Taq polymerase fragment
02/17/2005US20050037411 Thermostable peroxide-driven cytochrome P450 oxygenase variants and methods of use
02/17/2005US20050037395 Product
02/17/2005US20050037392 Optical sorting method
02/17/2005US20050037391 Polypeptide
02/17/2005US20050037380 Novel receptor-type phosphotyrosine phosphatase-alpha
02/17/2005US20050037376 Sulfatase polypeptide for use in treatment and prevention of microbial infection, cell proliferative, neurodegenerative and cardiovascular disorders
02/17/2005US20050037368 Microbial trypsin mutants having chymotrypsin activity and nucleic acids encoding same
02/17/2005US20050037355 Measuring intracellular adenosine triphosphate and/or gene expression in transgenic cell via monitoring luciferin bioluminescent signals; genetiic engineering and reporter molecules
02/17/2005US20050037346 Distinguish minority template in the presence of an excess of normal template with a thermostable ligase; useful for the detection of cancer-associated mutations; quantitative measure of the amount or ratio of minority template; a thermostable mutant ligase
02/17/2005US20050037088 Process of making flowable hemostatic compositions and devices containing such compositions
02/17/2005US20050037009 Methods and reagents for protease inhibition
02/17/2005US20050036999 Novel receptor-type phosphotyrosine phosphatase-alpha
02/17/2005US20050036995 Immunogens; tumor antigens; kits
02/17/2005DE10331291A1 Varianten der 3-Phosphoglyceratdehydrogenase mit reduzierter Hemmung durch L-Serin und dafür codierende Gene Variants of the 3-phosphoglycerate dehydrogenase with reduced inhibition by L-serine, and genes coding therefor
02/17/2005DE10328552A1 Producing defined enzyme mixture and/or metabolite mixture for fermentation of target substrates, by inoculating microorganisms in solid-phase bioreactor with inducer substrates and keeping mixed culture under appropriate conditions
02/17/2005CA2534481A1 Ubiquitin-specific protease
02/17/2005CA2534355A1 Compounds comprising lpa
02/17/2005CA2534296A1 Methods and compositions for targeted cleavage and recombination
02/17/2005CA2524767A1 Cyclodextrin affinity purification
02/16/2005EP1507008A2 Nucleotide sequences which code for the sahH gene
02/16/2005EP1507007A1 Cell cycle related proteins
02/16/2005EP1507003A1 Process for producing protein in cell-free protein synthesis system using thioredoxin fused protein expression vector
02/16/2005EP1507002A2 Thermostable Taq polymerase fragment
02/16/2005EP1507001A1 Novel (d)-2-hydroxy acid oxidase derived from microorganism and biochemical process for producing glyoxylic acid therewith
02/16/2005EP1507000A2 A thermostable ligase mediated DNA amplification system for the detection of genetic diseases
02/16/2005EP1506784A1 Identification of novel factors that block programmed cell death or apoptosis by targeting JNK
02/16/2005EP1506409A1 Assays for modulators of asparaginyl hydroxylase
02/16/2005EP1506318A2 Methods and compositions for regulation and manipulation of steroidogenesis
02/16/2005EP1506312A2 Metalloprotease peptide substrates and methods
02/16/2005EP1506305A2 Dna and amino acid sequences of a tyrosine-inducible tyrosine ammonia lyase enzyme from the yeast trichosporon cutaneum
02/16/2005EP1506303A2 Enzymes
02/16/2005EP1506298A1 Engineered yeast cells for producing recombinant proteins
02/16/2005EP1506294A1 Hydantoin racemase
02/16/2005EP1506293A2 Microbial conversion of glucose to para-hydroxystyrene