Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
03/2005
03/31/2005WO2005028620A2 Histone modifications as binary switches controlling gene expression
03/31/2005WO2005028615A2 Methods and compositions for detecting promoter activity and expressing fusion proteins
03/31/2005WO2005028614A2 Construction of a gst-cbd fusion protein having several enzymatic activities
03/31/2005WO2005028506A2 Crystal structure of fms-like tyrosine kinase
03/31/2005WO2005027830A2 Chimeric transcription factor decoy oligonucleotides
03/31/2005WO2005027725A2 Determination of ions using ion-sensitive enzymes
03/31/2005WO2005027629A2 Regulation of cardiac contractility and heart failure propensity
03/31/2005WO2005017134A3 Isozyme of autoclavable superoxide dismutase (sod) derived from curcuma longa l
03/31/2005WO2004104213A3 Nucleic acids and polypeptides of c1 bacteriophage and uses thereof
03/31/2005WO2004101780A3 Heparanase-derived peptides for vaccination of tumor patients
03/31/2005WO2004093645A3 Tn5 transposase mutants and the use thereof
03/31/2005WO2004087736A3 Uses of vascular endothelial growth factor and type i collagen inducible protein (vcip)
03/31/2005WO2004083241A3 Btc-interacting proteins and use thereof
03/31/2005WO2004081206A3 Novel polypeptides encoded by essential bacterial genes
03/31/2005WO2004081189A3 Multimodality imaging of reporter gene expression using a novel fusion vector in living cells and organisms
03/31/2005WO2004071272A3 Animal selected for lacking heparan sulfate 3-o-sulfotransferase-1 and uses thereof
03/31/2005WO2004056962A8 Constructs homogenously processed preparations of beta site app-cleaving enzyme
03/31/2005WO2004007705A9 Nucleotide sequences that encode deregulated phosphoglycerate dehydrogenases of coryneform bacteria and method for producing l-serine
03/31/2005WO2003040329A3 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
03/31/2005WO2003027308A3 56294 and 56629, novel human metalloproteases and uses thereof
03/31/2005WO2003018756A3 Methods for preparing purified prostaglandin e synthase
03/31/2005WO2002102323A3 Novel human histone deacetylases
03/31/2005WO2002072753A3 Thymidylate synthase peptides that bind to thymidylate synthase messenger rna
03/31/2005US20050070492 Use of a ribozyme for inhibiting gene expression; screening for oligonucleotide antisense agents
03/31/2005US20050070003 Glucanase enzyme mixture for use in textile treatment and laundering detergents
03/31/2005US20050070002 Histidine phosphatase interacting protein with 120kd
03/31/2005US20050070001 Uridine diphosphate/xylose:proteoglycan core protein beta -D-xlosyltransferase (XT) for use as tool in prevention and treatment of chronic inflammatory joint diseases
03/31/2005US20050070000 Polynucleotides and polypeptides encoded thereby distantly homologous to heparanase
03/31/2005US20050069999 Sh3 domain binding inhibitors
03/31/2005US20050069994 Nitrate reductase (NIR) defective escherichia for use in biosynthesis of arginine; bioreactors; supplements for medicine, animal feeds and cosmetics
03/31/2005US20050069993 Fermentation, concentration; gene overexpression by increasing copy number or operably linking to promoter; quantitative analysis; isolation of L-threonine or L-lysine
03/31/2005US20050069991 Preparing plasmids comprising providing solution of unligatable open circular plasmids, react unligatable open DNA with enzymes and generating 3'-hydroxyl, 5'-phosphate nicked plasmid, react with ligase generating relaxed closed plasmid, react with gyrase and recover supercoiled plasmid
03/31/2005US20050069990 R2D2: an enzyme of RNA silencing
03/31/2005US20050069988 Recombinant expression systems for production of low solubility foreign proteins specifically aminoglobulin
03/31/2005US20050069984 Identification of sortase gene
03/31/2005US20050069978 Phytase enzymes, nucleic acid sequences encoding phytase enzymes and vectors and host cells incorporating same
03/31/2005US20050069933 Transcritional replication enzyne for use in synthesizing RNA strands complementary to an RNA template; creating CDNA libraries
03/31/2005US20050069924 Differentially methylated sequences in pancreatic cancer
03/31/2005US20050069920 Using encapuslated gene sequences as tools for directed evolution of nucleic acids; microencapsulation and gene expression
03/31/2005US20050069908 DNA polymerase compositions for quantitative PCR and methods thereof
03/31/2005US20050069898 Freeze dried pellets/particle compriiang heat stable enzyme and manitol for use as tool in amplification of preferential polynucleotide sequences; DNA analysis and replication
03/31/2005US20050069887 Derived from Thermococcus; thermostability; sequencing; kits
03/31/2005US20050069885 Transformed yeast comprising defective urea carboxylase-allophanate hydrolase gene and reduce nitrogen catabolite repression for use as tool in fermentation of alcoholic beverages
03/31/2005US20050069878 Proteins associated with cell growth, differentiation, and death
03/31/2005US20050069877 Protein modification and maintenance polypeptides (PMOD) for use as diagnostic and therapeutic tools in treatment of prevention of gastrointestinal, cardiovascular, autoimmune/inflammatory, cell proliferative, developmental, epithelial, neurological, and reproductive disorders
03/31/2005US20050069876 Polypeptide for use in diagnosis, treatment and prevention of cell proliferative, autoimmune, inflammatory, cardiovascular, neurological and developmental disorders.
03/31/2005US20050069569 Osteocalcin; enzyme inhibitors; promote bone, teeth growth; administering Dna gene
03/31/2005US20050069562 Animal product free media and processes for obtaining a botulinum toxin
03/31/2005US20050069553 Domain which targets Rho protein; anticancer agents
03/31/2005US20050069551 cytotoxic compound, such as 3,5-bis(2-fluorobenzylidene)piperidin-4-one acetate bonded to protein; antitumor agents; anticarcinogenic agents; restenosis; antiarthritic agents;antiinflammatory agents
03/31/2005US20050069534 Method of isolation and purification of trypsin from pronase protease and use thereof
03/31/2005US20050069453 Methods for sterilizing preparations of urokinase
03/31/2005CA2770976A1 Cbh1 homologs and variant cbh1 cellulases
03/31/2005CA2540155A1 Excretable reporter systems
03/31/2005CA2538999A1 Regulation of cardiac contractility and heart failure propensity
03/30/2005EP1519192A2 HIV Protease inhibitor conjugates and antibodies useful in ummunoassay
03/30/2005EP1518936A1 Marker assisted selection of chicken against fishy taint
03/30/2005EP1518925A1 Crystal of glucokinase protein, and method for drug design using the crystal
03/30/2005EP1517993A2 Selective functionalization of hydrocarbons with isolated oxygenases and mediator-based regeneration
03/30/2005EP1517992A2 Retrons for gene targeting
03/30/2005EP1517989A2 Compositions and methods for the modulation of sphingolipid metabolism and/or signaling
03/30/2005EP1517981A2 Stabilization of granules
03/30/2005EP1517710A1 Pegylated factor vii glycoforms
03/30/2005EP1517699A1 Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation
03/30/2005EP1485404A4 Novel glucose 6-oxidases
03/30/2005EP1407047A4 METHOD OF DETERMINING A CHEMOTHERAPEUTIC REGIMEN BASED ON GLUTATHIONE-S-TRANSFERASE Pi EXPRESSION
03/30/2005EP1224298B1 Fibrinolytically active polypeptide
03/30/2005EP1187925B1 Pectate lyase fusion for expression and secretion of polypeptides
03/30/2005EP1025241B1 Multiply-substituted protease variants
03/30/2005EP0928290B1 Oligoribonucleotides and ribonucleases for cleaving rna
03/30/2005EP0791056B1 Lipid-cleavage enzyme complex
03/30/2005CN1602360A Methods of increasing endogenous erythropoietin (EPO)
03/30/2005CN1602357A Novel phytases and method for producing these phytases
03/30/2005CN1602354A Human coagulation factor VII polypeptides
03/30/2005CN1602202A A method for identification and development of therapeutic agents
03/30/2005CN1600854A New diatom manganese type superoxide dismutase and usage
03/30/2005CN1600853A Coarse enzyme preparation and method for preparing vanillin through biotransformation
03/30/2005CN1195063C Proteinase inhibitor fusion proteins
03/30/2005CN1195060C Nucleotide series of shaogengen mould delta-6 fatty acid dehydrogenase and its use
03/30/2005CN1195059C Method for preparing tablets of immobilization choline esterase
03/30/2005CN1195058C Oxaloacetae hydrolase deficient fungal host cells
03/29/2005US6872872 Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants
03/29/2005US6872870 Specific genetic modification of the activity of trehalose-6-phosphate synthase and expression in a homologous or heterologous environment
03/29/2005US6872816 Site-specific cleavage via thermostable nuclease
03/29/2005US6872815 Nucleic acid sequences to proteins involved in tocopherol synthesis
03/29/2005US6872813 Genes coding for tomato β-galactosidase polypeptides
03/29/2005US6872808 Nematode-extracted serine protease inhibitors and anticoagulant proteins
03/29/2005US6872807 Proteases from gram positive organisms
03/29/2005US6872805 Hepatitis C virus inhibitors
03/29/2005US6872702 Cyclic peptide; antitumor agents; antiinflammatory agents; tissue remodeling
03/29/2005US6872564 Method of producing copolymer polyester
03/29/2005US6872563 Compositions and methods for production of disulfide bond containing proteins in host cells
03/29/2005US6872560 Human hydrolytic enzymes
03/29/2005US6872559 Diagnosis of urogenital disorders
03/29/2005US6872558 Heparanase-2 a member of the heparanase protein family
03/29/2005US6872557 Gene encoding novel human secretory phospholipase A2
03/29/2005US6872556 Invention provides DNAs, vectors and host cells for the efficient production of various enzymes in the mevalonate pathway or for converting isopentyl pyrophosphate to farnesyl pyrophosphate synthase
03/29/2005US6872555 Nucleotide sequences for use in generating fructose polymers for food processing
03/29/2005US6872554 For therapy of Alzheimer's disease; immunization
03/29/2005US6872553 Nucleotide sequences which code for the pck gene