Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
08/1999
08/31/1999US5945312 Using mutant family b polymerase to incorporate fluorophore labeled nucleotides into complementary dna; mutant retains 3' to 5' exonuclease activity which increases accuracy; for sequence determinations and production of genetic probes
08/31/1999US5945304 Producing recombinant polypeptides by transfecting escherichia, controlling expression of target polypeptides using osmotic promoters; producing acetylcholinesterase, superoxide dismutases, growth hormones and hepatitis antigen
08/31/1999US5945301 A dna coding a polypeptide which is activated by transforming growth factor; useful for detecting agents that inhibit or promote signal transduction
08/31/1999US5945288 Method for cloning and producing the PmeI restriction endonuclease
08/31/1999US5945273 Human oxalyl-coa decarboxylase
08/31/1999US5945103 Process for producing thrombin
08/31/1999US5945102 Crustacean and fish derived multifunctional enzyme
08/31/1999US5944803 Isolatable multi-point serial communication utilizing a single universal asynchronous receiver and transmitter (UART)
08/31/1999CA2183315C Novel mercaptoacetylamido 1,3,4,5-tetrahydro-benzo[c]azepin-3-one disulfide derivatives useful as inhibitors of enkephalinase and ace
08/31/1999CA2183314C Novel 2-substituted indane-2-mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ace
08/31/1999CA2165669C Fruit specific promoters
08/31/1999CA2163120C Method of controlling insects
08/31/1999CA2055542C Pichia pastoris acid phosphatase gene
08/31/1999CA2018345C Stabilization of carboxyl esterase
08/26/1999WO1999042833A1 Protein kinase c
08/26/1999WO1999042830A1 Methods using pla2 as a marker of metastases and for the diagnosis of selected cancers
08/26/1999WO1999042601A1 PROCESS FOR THE OBTAINING OF HMG-CoA REDUCTASE INHIBITORS OF HIGH PURITY
08/26/1999WO1999042599A1 Isolated and purified nucleic acids comprising a gene specifically expressed in hop glands
08/26/1999WO1999042598A2 Hybrid seed production
08/26/1999WO1999042596A2 Phosphodiesterase 10
08/26/1999WO1999042595A1 Mismatch cleavage enzymes from extreme thermophiles and uses thereof
08/26/1999WO1999042594A1 Fungus and insect control with chitinolytic enzymes
08/26/1999WO1999042593A1 Compositions and methods for sensitizing and inhibiting growth of human tumor cells
08/26/1999WO1999042592A1 Methods for designing inhibitors of serine/threonine kinases and tyrosine kinases
08/26/1999WO1999042591A1 Method for producing biotin
08/26/1999WO1999042590A1 Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives
08/26/1999WO1999042572A1 Candida boidinii dihydroxyacetone synthase promoter
08/26/1999WO1999042568A1 Use of bacteria endowed with arginine deiminase to induce apoptosis and/or reduce an inflammatory reaction and pharmaceutical or dietetic compositions containing such bacteria
08/26/1999WO1999042567A1 Alkaline bacillus amylase
08/26/1999WO1999042566A1 Lipase variant
08/26/1999WO1999042565A1 Herbicides test method
08/26/1999WO1999042562A1 NOVEL pgsA
08/26/1999WO1999042133A1 Inhibitors of complement activation
08/26/1999WO1999042120A1 Tadg-15: an extracellular serine protease overexpressed in breast and ovarian carcinomas
08/26/1999WO1999041984A1 INTERACTION BETWEEN THE MEC1-DEPENDENT DNA SYNTHESIS CHECKPOINT AND G1 CYCLIN FUNCTION IN $i(SACCAROMYCES CEREVISIAE)
08/26/1999WO1999029844A3 Novel retroelements zam and idemfix, and their integrase
08/26/1999WO1999024571A3 Differentially expressed genes in cardiac hypertrophy and their uses in treatment and diagnosis
08/26/1999WO1999023113A3 Rho family antagonists and their use to block inhibition of neurite outgrowth
08/26/1999WO1999020769A3 Multiply-substituted protease variants
08/26/1999DE19810998C1 New metal-containing ribonucleotide proteins with nuclease and phosphatase activities, used e.g. for cell-selective inhibition of protein synthesis and inhibition of tumors
08/26/1999DE19806872A1 Production of biotin by expressing S-adenosyl-methionine synthase and second biotin synthesis gene in host cells
08/26/1999CA2321264A1 Method for producing biotin
08/26/1999CA2321224A1 Phosphodiesterase 10
08/26/1999CA2321184A1 Methods for designing inhibitors of serine/threonine kinases and tyrosine kinases
08/26/1999CA2321180A1 Isolated and purified nucleic acids comprising a gene specifically expressed in hop glands
08/26/1999CA2321140A1 Inhibitors of complement activation
08/26/1999CA2321052A1 Process for the obtaining of hmg-coa reductase inhibitors of high purity
08/26/1999CA2320843A1 Methods using pla2 as a marker of metastases and for the diagnosis of selected cancers
08/26/1999CA2320808A1 Compositions and methods for sensitizing and inhibiting growth of human tumor cells
08/26/1999CA2320787A1 Protein kinase c
08/26/1999CA2320759A1 Alkaline bacillus amylase
08/26/1999CA2311649A1 Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives
08/25/1999EP0937775A2 Beta 1,3-N-acetylglucosaminyltransferase, DNA encoding it and its use
08/25/1999EP0937774A1 Lactic acid bacteria having a reduced pyruvate dehydrogenase activity and use thereof
08/25/1999EP0937773A2 Process for the preparation of enzymes and enzyme complexes
08/25/1999EP0937156A2 Preparation of d-amino acids by direct fermentative means
08/25/1999EP0937154A2 Chimera gene with several herbicide resistant genes, plant cell and plant resistant to several herbicides
08/25/1999EP0937152A2 Screening for and use of an esterase for a stereospecific resolution
08/25/1999EP0937139A1 Amidase
08/25/1999EP0937138A1 Cellulase variants
08/25/1999EP0937098A1 Recombinational cloning using engineered recombination sites
08/25/1999EP0936912A1 Inhibitors of cysteine protease
08/25/1999CN1226932A Process for inactivation of genes which code for enzymes for catabolism of phenyl acetate, plasmids involved in such process and strains transformed therewith
08/25/1999CN1226926A Plasminogen Activator capable of being activated by thrombin
08/25/1999CN1226925A Phosphate starvation-inducible proteins
08/25/1999CN1226842A Preservation by foam formation
08/24/1999US5942662 Inducible herbicide resistance
08/24/1999US5942661 Transformation of crop susceptible to mycotoxin contamination under the regulation of operable promoter with gene encoding lipoxygenase pathway enzyme that produces 13-hydroperoxy linoleic acid sufficient to inhibit mycotoxin production
08/24/1999US5942660 A plant having a genome of recombinant dna encoding increased levels of beta-ketothiolase, a beta-ketoacyl-coenzyme a reductase, a polyhydroxyalkanate symthase and a deregulated threonine deaminase
08/24/1999US5942659 Producing transgenic oleaginous plant having lipase gene coding for lipase enzyme; collecting seeds or fruits; crushing seeds or fruits with lipids; incubating to effect enzymatic hydrolysis; extracting fatty acids
08/24/1999US5942657 Inhibition of polygalacturonase and pectin esterase in a tomato plant by introducing into the plant a single control gene having dna regions homologous to the tomato genes and a promoter operative in tomato plants adapted to transcription
08/24/1999US5942492 Cyclic peptides that bind to urokinase-type plasminogen activator receptor
08/24/1999US5942434 Regulatory sequence from phophoglycerate kinase operably linked to coding sequence of exogenous gene; for gene therapy; in situ expression of enzymes which convert prodrugs to active anticarcinogenic/antitumor drugs or cytokines
08/24/1999US5942431 DNA sequences encoding lipases and method for producing lipases
08/24/1999US5942430 Esterases
08/24/1999US5942429 DEAH-box proteins
08/24/1999US5942428 Useful for solving the crystal and solution structures of the tyrosine kinase domains and for identifying compounds that bind to the tyrosine kinase domains and compounds that bind to domains of receptor and non-receptor tyrosine kinase
08/24/1999US5942427 N-acetylmannosamine dehydrogenase gene and novel recombinant DNA as well as a method for production of N-acetylmannosamine dehydrogenase
08/24/1999US5942426 Having xenobiotic oxidizing activity
08/24/1999US5942424 Method for the enzymatic production of hydrogen
08/24/1999US5942423 Effective and relatively inexpensive method for producing anticholesterol agents using whole cells, a cell free extract, a cell free culture media, or a solution
08/24/1999US5942411 Process of producing B-lactam antibiotics applying microorganisms with increased ligase activity
08/24/1999US5942400 Assays for detecting β-secretase
08/24/1999US5942395 Hybrid ribozymes and methods of use
08/24/1999US5942393 Method for the detection of the presence or absence of methylthioadenosine phosphorylase (MTASE) in a cell sample by detection of the presence or absence of MTASE encoding nucleic acid in the cell sample
08/24/1999US5942389 Developing a genetic suppressor protein with resistance to platinum-based cytotoxic drugs; synthesizing random cdna fragments, transferring dna into expression vector, transducing eukaryotic cells and isolating modified cells
08/24/1999US5942386 Identifying inhibitors of candida albicans topoisomerase i protein
08/24/1999US5942264 Dairy product comprising ice cream mix including milk, butter fat, cream, lactose, and lactase enzyme; lactose is hydrolyzed prior to ingestion of the product by lactose intolerant individual
08/24/1999US5942262 Comprising protease, an enzyme, and flour; dough consistency that is between the consistency of bread dough and of fully hydrolyzed dough; substituting metabilusfite with the enzyme composition
08/24/1999US5942254 An infant milk formulas that have some of the advantageous properties of human milk and avoid the disadvantages with bovine milk such as allergic reactions and incomplete digestion, including a biosynthetic human milk proteins
08/24/1999US5942228 An amino acid sequence protein for the manufacture of complex carbohydrates and as a target for screening of small molecule antagonists of enzyme activity; treating diseases of cellular fucosylation
08/24/1999CA2110510C Cold tolerances in plants
08/19/1999WO1999041411A2 Method for diagnosis and treatment of disorders of carbohydrate metabolism
08/19/1999WO1999041404A2 Novel means and methods for the preparation and activation of nucleoside and nucleotide based drugs
08/19/1999WO1999041398A1 Vectors, cells and methods for the production of deleterious viral eukaryotic gene transfer vectors
08/19/1999WO1999041397A1 Anti-viral vectors
08/19/1999WO1999041395A1 Methods and compositions for producing plants and microorganisms that express feedback insensitive threonine dehydratase deaminase
08/19/1999WO1999041394A1 Nucleotide sequences encoding maize rad51
08/19/1999WO1999041392A1 Nucleic acid comprising the sequence of a promoter inductible by stress and a gene sequence coding for a stilbene synthase
08/19/1999WO1999041390A2 Expression vector for the production of dead proteins