Patents for C12N 9 - Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes (141,535)
09/1999
09/14/1999US5952210 A nucleic acid which codes for a glutathione-s-transferase; treatment of asthma, antiallergens, antihistamines, bronchodilator agents
09/14/1999US5952209 Diagnosis and treatment of disorders associated with immune response, cell development, antiproliferative agents, genetic eye disorders and vision defects
09/14/1999US5952208 A genetically engineered microorganism that contain heterologous nucleic acids which code for desulfurization enzymes; treatment of fossil fuel that contain organosulfur compounds; pollution control
09/14/1999US5952205 Process for processing sucrose into glucose and fructose
09/14/1999US5952204 β-fructofuranosidase, its preparation and uses
09/14/1999US5952203 Oligosaccharide synthesis using activated glycoside derivative, glycosyl transferase and catalytic amount of nucleotide phosphate
09/14/1999US5952196 A polynucleotide from streptococcus; for screening bactericides and antibiotics, diagnosis pneumonia, bacterial meningitis, sinusitis, conjuctivitis and infections of the cerebrospinal fluid
09/14/1999US5952189 Screening for enzyme inhibitors for antiproliferative agents, antitumor agents, treatment for leukemia, acquired immune deficiency syndrome, nervous system disorders
09/14/1999US5952181 Hybridizing polynucleotide sequence to complementary polynucleotide forming a complex, detecting complex formation; anticarcinogenic agent, treatment of psychological disorders, alzheimer's disease
09/14/1999US5952177 Human cytosolic isocitrate dehydrogenase
09/14/1999US5952169 Identification of DNA-damaging substances by means of cell lines capable of overexpressing poly (ADP-ribose)--polymerase
09/14/1999US5952034 Increasing the digestibility of food proteins by thioredoxin reduction
09/14/1999US5952011 Human placental transglutaminase polypeptide and nucleotide sequences encoding it, or an allelic variant thereof; use as wound-healing agent
09/14/1999US5951981 Thrombolytic agents with antithrombotic activity
09/14/1999US5951979 Mutants (alanine replacing an aspartic acid) lack or have reduced catalytic activity but retain ability to bind substrate resulting in formation of observable and isolatable complex and less immunogenic effects
09/14/1999CA2175379C System for coupling machine tools
09/14/1999CA2079229C Ubiquitin-specific protease
09/14/1999CA2071446C Synthetic catalytic oligonucleotide structures
09/14/1999CA1340748C Synthetic hiv protease gene and method for its expression
09/14/1999CA1340746C Cloning and expression vectors in an actinomycete strain; process for modifying said strain; actinomycete strain thus obtained and process for preparing proteins
09/14/1999CA1340740C Co-expression in eukaryotic cells
09/14/1999CA1340733C Regulatory region for heterologous gene expression in yeast
09/13/1999CA2265239A1 Genetically engineered l-sorbose reductase-deficient mutants
09/11/1999CA2253946A1 Method for regulating cell death
09/10/1999WO1999045129A1 Method for the induction of pathogen resistance in plants
09/10/1999WO1999045127A2 Enhanced prodrug activation
09/10/1999WO1999045126A2 Enhanced prodrug activation
09/10/1999WO1999045125A2 Methods and compositions for regulating cell death and enhancing disease resistance to plant pathogens
09/10/1999WO1999045124A2 Modified forms of pullulanase
09/10/1999WO1999045123A1 Recombinant staphylococcus thioredoxin reductase, and inhibitors thereof useful as antimicrobial agents
09/10/1999WO1999045122A1 Modification of fatty acid metabolism in plants
09/10/1999WO1999045107A1 Novel calpain and dna encoding the same
09/10/1999WO1999045106A1 Cholesterol oxidase
09/10/1999WO1999045105A2 Highly crystalline urokinase
09/10/1999WO1999045026A1 Method for increasing the serum half-life of a biologically active molecule
09/10/1999WO1999044943A2 Vectors and viruses used in gene therapy
09/10/1999WO1999032617A3 Expression cloning in filamentous fungi
09/10/1999WO1999028463A3 Methods for the degradation and detoxification of organic material using urine produced by transgenic animals
09/10/1999WO1999027124A9 Enzymatic starch saccharification including a membrane separation step
09/10/1999WO1999027102A9 Cd4+ t-lymphocyte protease genes and inhibitors thereof
09/10/1999WO1999027081A9 Alpha/beta hydrolase-fold enzymes
09/10/1999CA2322664A1 Enhanced prodrug activation
09/10/1999CA2322622A1 Highly crystalline urokinase
09/10/1999CA2322382A1 Method for the induction of pathogen resistance in plants
09/10/1999CA2321270A1 Novel calpain and dna encoding the same
09/10/1999CA2316612A1 Methods and compositions for regulating cell death and enhancing disease resistance to plant pathogens
09/10/1999CA2231621A1 Consensus sequence to identify acyltransferase enzymes in plants
09/09/1999DE19808889A1 Vektoren und Viren zur Gentherapie Vectors and viruses for gene therapy
09/09/1999DE19808717A1 Selecting genes that express mutant proteins of high stability, especially enzymes and binding proteins
09/09/1999DE19808192A1 Diisopropylfluorophosphatase sowie deren Verwendung und Herstellung Diisopropyl fluorophosphatase and their use and production
09/09/1999DE19802569A1 New fragment of the lethal toxin from Clostridium bacterium, useful for treating cancer
09/08/1999EP0940470A2 A fusion protein and its use for the simultaneous detection of autoantibodies related to insulin-dependent diabetes mellitus
09/08/1999EP0940469A2 Cloning by complementation and related processes
09/08/1999EP0940409A1 Process for the preparation of sphingolipids and sphingolipid derivatives
09/08/1999EP0939832A1 Mitochondrial dna mutations that segregate with late onset diabetes mellitus
09/08/1999EP0939830A1 A method of improving the production of biomass or a desired product from a cell
09/08/1999EP0939829A1 Methods of modulating melanin synthesis
09/08/1999EP0939823A1 Genes encoding telomerase proteins
09/08/1999EP0939822A2 Use of mutated macrolide binding protein for the prevention of guhd
09/08/1999EP0939821A2 G-beta-gamma regulated phosphatidylinositol-3' kinase
09/08/1999EP0939820A1 Nucleic acid sequences that encode a cell growth regulatory protein and uses thereof
09/08/1999EP0939818A1 Recombinant toxin fragments
09/08/1999EP0939814A1 Fringe proteins and notch signalling
09/08/1999EP0939806A1 Fanconi gene 1
09/08/1999EP0939802A1 spsA POLYNUCLEOTIDES AND POLYPEPTIDES
09/08/1999EP0939801A1 An enzyme with amylase activity
09/08/1999EP0939800A2 HELICOBACTER ANTIGEN (gamma-GLUTAMYLTRANSFERASE) AND SEQUENCES ENCODING THE SAME
09/08/1999EP0939799A1 Enzymatic cofactor cycling using soluble pyridine nucleotide transhydrogenase
09/08/1999EP0939798A2 Antifungal proteins, dna coding therefore, and hosts incorporating same
09/08/1999EP0939764A2 Molecular genetic construction of vaccine strains of pasteurellaceae
09/08/1999EP0353250B1 The engineering of electrostatic interactions at metal ion binding sites for the stabilization of proteins
09/08/1999CN1228126A Glyceraldehyde-3-phosphate dehydrogenase and nuclear restoration of cytoplasmic male sterility
09/08/1999CN1228120A Phytase from bacillus subtilis, gene encoding said phytase, method for its production and use
09/08/1999CN1227872A Process for preparing enzyme encoded by cephalosporin acetylthydrolase gene
09/08/1999CN1227870A Genes of purine biosynthesis from ashbya gossypli and use thereof in microbial riboflavin synthesis
09/07/1999US5948955 Transgenic plants having altered anthocyann levels
09/07/1999US5948900 The present invention relates generally to the fields of bacterial capsule formation and the genes responsible for polysaccharide synthesis.
09/07/1999US5948898 Methoxyethoxy oligonucleotides for modulation of protein kinase C expression
09/07/1999US5948894 Immunoadsorbent reagents
09/07/1999US5948885 Mitogen-activated protein kinase p38-2 and methods of use therefor
09/07/1999US5948765 Inhibition of intracellular signal transduction by 14-3-3-binding peptides
09/07/1999US5948759 Factor VII fragment 82-128 and its use in blood-clotting disorders
09/07/1999US5948682 Preparation of heterologous proteins on oil bodies
09/07/1999US5948678 This invention also relates to the use of i-scei for mapping eukaryotic genomes and for in vivo site directed genetic recombination.
09/07/1999US5948675 Host-vector system which can be used in gene therapy
09/07/1999US5948672 May be employed in the treatment cellulose-containing fabrics for harshness reduction or color clarification or to provide a localized variation in the color of such fabrics, or it may be employed in the treatment of paper pulp.
09/07/1999US5948670 Process for the isolation and characterization of a gene enzyme system for inactivation of the herbicide phenmedipham and transfer of the gene into plants to produce herbicide-tolerant plants
09/07/1999US5948669 As probes and primers; for diagnosis and treatment of osteoporosis, oral diseases, paget's disease; antiarthritic agents, anticarcinogenic/antitumor/antimetastasis agents
09/07/1999US5948668 Gene expression of proenzyme from recombinant bacterial cell, solubilizing proenzyme, incubation at alkaline ph permitting folding, cleaving to activate enzyme, purification of active enzyme; cost efficient and pure
09/07/1999US5948667 Xylanase obtained from an anaerobic fungus
09/07/1999US5948666 Isolation and identification of polymerases
09/07/1999US5948665 Enzyme with increased storage stability in solution, heat resistance, and greater substrate specificity for glucose and fructose; as determination reagent
09/07/1999US5948664 Polypeptide for phosphatidyl inositol 3-kinase; for diagnosis and treatment of disorders caused by abnomalities in signal transduction such as growth factor activation cascade which leads to activation of ras oncogene; anticarcinogenic agents
09/07/1999US5948663 The present invention relates to a thermostable enzyme having dna polymerase i activity useful in nucleic acid synthesis by primer extension reaction.
09/07/1999US5948662 Processing protein, non-proteinaceous amino acid polymer, or peptide by contacting glutamine and lysine residues with enzyme forming intermolecular or intramolecular bonds; enzyme is not calcium dependent
09/07/1999US5948661 Myxococcus peroxidase
09/07/1999US5948660 Nucleotide sequence which codes for enzyme from rhodotorula gracilis; production of semisynthetic cephalosporins; antitumor agents
09/07/1999US5948659 Recombinant fructosyl amino acid oxidase
09/07/1999US5948658 Catalytic antibodies have unique potential for the treatment of cocaine addiction and overdose.
09/07/1999US5948657 Phenylalanyl-tRNA synthetase from Staphylococcus aureus