Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
02/1999
02/09/1999US5869262 Quantitative immunoassay by contacting serum from patient with antibodies against circulating intercellular adhesion molecule-r, detecting binding; higher levels indicate progression of systematic lupus erythematosus
02/09/1999US5869259 Isolated polynucleotide that codes for a protease inhibitor that regulates many physiological intracellular processes; diagnosis of inflammatory and cell proliferation diseases;antiinflammatory/anticarcinogenic/antiproliferative
02/09/1999US5869258 Detection system for mutagens that identifies mutagenic changes
02/09/1999US5869257 Nucleic acid indicator for determining the expression of melanocortin-4 receptors by hybridization to complementary sequence; physiological therapy involving organs and tissues expressing receptor; drug screening
02/09/1999US5869254 In vitro splicing non-viral target nucleic acid with another to correct defect; for gene therapy, viricides
02/09/1999US5869253 Enzymatic ribozyme molecule having a substrate binding site and an active site that cleaves hepatitis c virus rna; diagnosis and viricides
02/09/1999US5869250 Method for the identification of peptides that recognize specific DNA sequences
02/09/1999US5869248 Targeted cleavage of RNA using ribonuclease P targeting and cleavage sequences
02/09/1999US5869247 Natural resistance associated macrophage protein and uses thereof
02/09/1999US5869246 Triplex Oligonucleotides targeted to p120
02/09/1999US5869241 Method of determining DNA sequence preference of a DNA-binding molecule
02/09/1999US5869239 Isolating overlapping dna sequences for building an extended physical map of a chromosomal region.
02/09/1999US5869236 Detecting mutations in nucleic acid sample by subjecting double-stranded hybrid stabilized by covalent photobridging with photoactivatable intercalating agent to denaturing gradient gel electrophoresis and comparing to control
02/09/1999US5869235 Dna coding for the coat protein of virus isolated from infected vine plants; for detection of vrial infection by reverse transcription polymerase chain reaction and southern blotting
02/09/1999US5869230 Gene transfer into the kidney
02/09/1999US5869064 Protein rib, a cell surface protein that confers immunity to many strains of the group B Streptococcus: process for purification of the protein, reagent kit and pharmaceutical composition
02/09/1999US5869057 Administering a fusion protein comprising pentamers of escherichia coli labile toxin subunit b and human chorionic gonadotropin
02/09/1999US5869050 Administering to patient antibody against b7 antigen and immunosuppressive agent in synergistic mixture; treatment of transplant rejection, graft versus host disease, rheumatoid arthritis
02/09/1999US5869046 Altered polypeptides with increased half-life
02/09/1999US5869045 Polypeptide comprising antigen-binding region of monoclonal antibody produced by specified hybridoma
02/09/1999US5869041 Delivery of bioactive compounds to an organism
02/09/1999US5869040 Administering interfering mutant proto-oncogene or oncoprotein to target cell
02/09/1999US5869037 Adenoviral-mediated gene transfer to adipocytes
02/09/1999US5869036 Live attenuated vaccines based on CP45 HPIV-3 strain and method to ensure attenuation in such vaccine
02/09/1999CA2121180C Norbornane type ester hydrolase
02/09/1999CA1341437E Method of using eukaryotic expression vectors comprising the bk virus enhancer
02/09/1999CA1340384C Methode d'utilisation de vecteurs d'expression eucaryotes comprenant un amplificateur du virus bk
02/09/1999CA1340382C Process for the preparation of 2-arylpropionic acids
02/09/1999CA1340381C Recombinant fusion proteins
02/08/1999CA2239223A1 Novel rpoa
02/08/1999CA2239222A1 Novel rpoa
02/06/1999CA2239256A1 Novel lgt
02/05/1999CA2239817A1 Novel prokaryotic polynucleotides, polypeptides and their uses
02/05/1999CA2239270A1 Novel phosphoribosyl transferase
02/05/1999CA2238673A1 Novel aminopeptidase
02/04/1999WO1999005591A2 Method and apparatus for providing a bioinformatics database
02/04/1999WO1999005574A1 Method and system for providing a probe array chip design database
02/04/1999WO1999005527A2 Methods for diagnosis and therapy of autoimmune disease, such as insulin dependent diabetes mellitus, involving retroviral superantigens
02/04/1999WO1999005324A1 System for providing a polymorphism database
02/04/1999WO1999005323A1 Gene expression and evaluation system
02/04/1999WO1999005322A1 Computer method and system for correlating sequencing data by ms
02/04/1999WO1999005321A1 Amplification and other enzymatic reactions performed on nucleic acid arrays
02/04/1999WO1999005320A1 Multiple functionalities within an array element and uses thereof
02/04/1999WO1999005319A2 Methods and compounds for analyzing nucleic acids by mass spectrometry
02/04/1999WO1999005316A1 A METHOD FOR IDENTIFYING MYCOBACTERIAL SPECIES BY COMPARATIVE SEQUENCE ANALYSIS OF rpoB GENE
02/04/1999WO1999005315A2 Nucleic acid sequence analysis
02/04/1999WO1999005314A1 Use of 2'-o-methyl rna as hybridisation probe
02/04/1999WO1999005313A2 Method for typing of minor histocompatibility antigen ha-1
02/04/1999WO1999005311A1 High specificity homocysteine assays for biological samples
02/04/1999WO1999005303A1 Preparation of lipid-nucleic acid particles using a solvent extraction and direct hydration method
02/04/1999WO1999005302A1 Conjugates of transporter peptides and nucleic acid analogs, and their use
02/04/1999WO1999005301A1 Gene transfer method with the use of serum-free medium
02/04/1999WO1999005300A2 Ghrh expression system and methods of use
02/04/1999WO1999005299A1 Methods of using cytochrome p450 reductase for the enhancement of p450-based anti-cancer gene therapy
02/04/1999WO1999005298A1 Genes controlling phytate metabolism in plants and uses thereof
02/04/1999WO1999005297A1 T7 promoter-based expression system
02/04/1999WO1999005296A1 Method for selecting transformed cells
02/04/1999WO1999005295A1 Composition and method for targeted integration into cells
02/04/1999WO1999005294A1 INTRACELLULAR INHIBITORS OF Gq PROTEIN SIGNALING
02/04/1999WO1999005293A1 Procedure for preparing enriched gene expression libraries
02/04/1999WO1999005292A1 Method for gene screening with the use of nuclear receptors
02/04/1999WO1999005291A2 Aggrecan degrading metallo proteases
02/04/1999WO1999005290A1 Novel serine protease
02/04/1999WO1999005289A1 Recombinant lysostaphin analogs
02/04/1999WO1999005288A2 Method for producing and identifying new hydrolases having improved properties
02/04/1999WO1999005287A1 Genes encoding proteins having transglycosylation activity
02/04/1999WO1999005286A1 Plant atp-phosphoribosyl transferase and dna coding therefor
02/04/1999WO1999005285A1 Method for producing biotin
02/04/1999WO1999005283A2 Biosynthesis genes and transfer of 6-desoxy-hexoses in saccharopolyspora erythraea and in streptomyces antibioticus and their use
02/04/1999WO1999005282A1 Non-b non-c non-g hepatitis virus gene, polynucleotide, polypeptide, virion, method for separating virion, and method for detecting virus
02/04/1999WO1999005281A1 Novel nucleic acid molecules and uses therefor
02/04/1999WO1999005280A1 Mammalian cytokine: interleukin-b30 and related reagents
02/04/1999WO1999005279A1 Mcp-1 analogs
02/04/1999WO1999005278A1 Lens epithelial cell derived growth factor
02/04/1999WO1999005277A1 A recombinant expression vector of human parathyroid hormone using phosphoribulokinase as a fusion partner
02/04/1999WO1999005276A1 Human chloride ion channel zsig44
02/04/1999WO1999005275A1 Secreted proteins encoded by human chromosome 13
02/04/1999WO1999005274A1 Method of identifying novel g-protein receptors and their functions
02/04/1999WO1999005273A1 Gmeb nucleic acids, proteins, and uses thereof
02/04/1999WO1999005272A1 Use of transcription factor brn-3a
02/04/1999WO1999005271A1 Soluble variants of the ige receptor fc-epsilon-ri-alpha with increased affinity
02/04/1999WO1999005270A2 Crustacean antimicrobial peptides, called penaiedines
02/04/1999WO1999005269A2 Transcriptional silencer protein nrf
02/04/1999WO1999005268A1 Production of erythropoietin by endogenous gene activation
02/04/1999WO1999005267A1 Identification of human cell lines for the production of human proteins by endogenous gene activation
02/04/1999WO1999005266A2 Trans-species nuclear transfer
02/04/1999WO1999005265A2 Improved plastid transformation of higher plants and production of transgenic plants with herbicide resistance
02/04/1999WO1999005264A2 Production of human mutant proteins in human cells by homologous recombination
02/04/1999WO1999005256A2 Method for cloning secreted proteins
02/04/1999WO1999005255A1 Methods for enhancing or reducing preimplantation embryo survival rates
02/04/1999WO1999005183A1 Cationic polymers, complexes associating said cationic polymers with therapeutically active substances comprising at least a negative charge, in particular nucleic acids, and their use in gene therapy
02/04/1999WO1999005180A1 Collagen type i and type iii adhesive compositions
02/04/1999WO1999005177A1 Methods and compositions for identifying modulators of g-protein-coupled receptors
02/04/1999WO1999005175A2 Diagnosis and treatment of diseases using anti-anti-t-cell receptor vbeta anti-bodies or peptides which are recognized by said antibodies, and endocrine secretion regulatory protein i (esrp1)
02/04/1999WO1999005171A1 NOVEL ESTROGEN RECEPTOR β AND ISOFORMS
02/04/1999WO1999005170A1 NOVEL ESTROGEN β RECEPTOR AND ISOFORMS
02/04/1999WO1999005168A1 Mycobacterium strain with modified erp gene and vaccine composition containing same
02/04/1999WO1999005159A2 Staphylococcus specific nucleic acid molecule, test kit and utilization of the nucleic acid molecule and test kit
02/04/1999WO1999005094A1 Novel compositions for the delivery of negatively charged molecules
02/04/1999WO1999004896A1 Polyethylenimine-based biomolecule arrays