Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
03/1999
03/03/1999CN1209546A Duplicating, detecting and quantizing of taget analyte of nucleotide series in sample by using sterically defined taget analyte
03/03/1999CN1209455A DNA of encoding plasminogen excited protein
03/03/1999CN1209437A Improved method for obtaining isulin precursor having correctly-bonded cystine bond
03/03/1999CN1209436A Human semaphorin L(H-SemaL) and corresponding semaphorins in other species
03/03/1999CN1209340A Curative vaccinum for hepatitis B and preparing method therefor
03/03/1999CA2242313A1 Signal recognition particle polypeptides and polynucleotides
03/02/1999US5877403 Papaya ringspot virus protease gene
03/02/1999US5877402 DNA constructs and methods for stably transforming plastids of multicellular plants and expressing recombinant proteins therein
03/02/1999US5877401 Targeting and enhancing RNA-RNA recombination
03/02/1999US5877400 Transgenic methods and compositions for producing parthenocarpic fruits and vegetables
03/02/1999US5877399 Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
03/02/1999US5877398 Biological systems incorporating stress-inducible genes and reporter constructs for environmental biomonitoring and toxicology
03/02/1999US5877397 Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
03/02/1999US5877396 Mice mutant for functional Fc receptors and method of treating autoimmune diseases
03/02/1999US5877309 Nucleotide sequences which suppress expression of jun n-terminal kinase oncogene by complementary hybridization; antiproliferative agents, antitumor agents, anticarcinogenic agentsand antimetastasis agents
03/02/1999US5877308 Synthetic oligonucleotide that is complemtary to capl mrna including the 3' splice site thereby inhibiting capl gene expression; anticarcinogenic agents
03/02/1999US5877306 Modified Bacillus thuringiensis insecticidal-crystal protein genes and their expression in plant cells
03/02/1999US5877305 DNA encoding biosynthetic binding protein for cancer marker
03/02/1999US5877302 Compacted nucleic acids and their delivery to cells
03/02/1999US5877293 CDR grafted anti-CEA antibodies and their production
03/02/1999US5877291 Multivalent single chain antibodies
03/02/1999US5877290 Humanized antibody fragment that binds a polypeptide sequence encoded by cdna of an anti-hypercalcemic hormone; treatment of electrolyte disorders, kidney failure, bone and heart disorders, osteoporosis, paget's disease
03/02/1999US5877285 Lymphocyte specific chemokines; for diagnostic kits; antiproliferative agents; anticancer agents; autoimmune disorders
03/02/1999US5877282 Peptide inhibitors of nuclear protein translocation having nuclear localization sequences and methods of use thereof
03/02/1999US5877281 Since del-1 is expressed in endothelial cells and certain cancer cells, it may be useful as an endothelial cell and tumor marker. in addition, the ability of del-1 protein to inhibit vascular formation provides for its use as an
03/02/1999US5877280 Thermostable muts proteins
03/02/1999US5877279 Materials for the production of nanometer structures and use thereof
03/02/1999US5877274 Antimicrobial cationic peptides
03/02/1999US5877273 Antigenic polypeptide mycobacteria; for production of antibodies; for simple diagnosis of tuberculosis and leprosy
03/02/1999US5877220 Delivering macromolecules to cells
03/02/1999US5877179 Cystic fibrosis
03/02/1999US5877162 Short external guide sequences
03/02/1999US5877160 Compositions and methods of treatment of androgen-associated baldness using antisense oligomers
03/02/1999US5877159 The gene may encode, e.g., a vaccine antigen, an therapeutic agent, an immunoregulatory agent or a anti-sense rna or a catalytic rna.
03/02/1999US5877152 Method for isolation of highly pure von Willebrand Factor
03/02/1999US5877023 Atomizing gold microparticles in dna solution into fog which is pressurized and accelerated through capillaries toward cells fixed to support, particles penetrate membranes and walls allowing dna to enter; for transgenic plants, animals
03/02/1999US5877022 Ribozymes targeted to APO(a) RNA
03/02/1999US5877021 Induction of graft tolerance, treatment of autoimmune diseases, inflammatory disorders and allergies in particular, by inhibition of b7-1, b7-2, b7-3 and cd40.
03/02/1999US5877020 Promoter for the receptor tyrosine kinase, Tie
03/02/1999US5877018 Synthetic eukaryotic promoters containing two inducible elements
03/02/1999US5877017 Isolated nucleic acid molecule encoding peptides which form complexes with MHC molecule HLA-Cw*1601 and uses thereof
03/02/1999US5877016 Human trk receptors and neurotrophic factor inhibitors
03/02/1999US5877015 APP770 mutant in alzheimer's disease
03/02/1999US5877013 Rhodosporidium D-amino acid oxidase
03/02/1999US5877012 Class of proteins for the control of plant pests
03/02/1999US5877011 Chimeric adenoviral vectors
03/02/1999US5877010 Thymidine kinase mutants
03/02/1999US5877006 DNAs encoding chimeric immunoglobulin light or heavy chains and fragments thereof having variable regions derived from monoclonal antibody 7E3, and vectors and host cells comprising same
03/02/1999US5877003 Thermostable Mutants of D-N-α-carbamoylase
03/02/1999US5877002 Enzyme from agrobacterium radiobacter with amino acid substitutions, for efficient production of d-alpha amino acids used in chemical intermediates for sweetners, insecticides, cephalosporins, penicillins
03/02/1999US5877001 Polynucleotide encoding thermostable enzyme isolated from thermococcus; for removal of l-arginine, l-phenylalanine, or l-methionine from n-terminal of peptides in peptide synthesis reactions when ester functionality is present
03/02/1999US5876997 Phytase
03/02/1999US5876995 Bioluminescent novelty items
03/02/1999US5876991 Dna sequence which encodes tylactone synthase domain from strepomyces fradiae; for antibiotics, antitumor agents, immunosuppressants
03/02/1999US5876988 Selection marker gene free recombinant strains: method for obtaining them and the use of these strains
03/02/1999US5876987 Method, DNA and bacteria for hyperproduction of an antibiotic due to disruption of an AbsA gene
03/02/1999US5876985 Methods and compositions for the preparation of recombinant Trichomonas vaginalis proteins and peptides
03/02/1999US5876979 RNA component of mouse, rat, Chinese hamster and bovine telomerase
03/02/1999US5876978 Concurrent amplification of target and control cdna in presence of mutant competitive templates, comparing relative band densities; for analysis of small specimens
03/02/1999US5876976 Method for reducing carryover contamination in an amplification procedure
03/02/1999US5876975 Trehalose phosphorylase its preparation and uses
03/02/1999US5876973 Method for making antibodies which specifically bind to glial growth factors
03/02/1999US5876972 Nucleic acid molecules coding for tumor suppressor proteins and methods for their isolation
03/02/1999US5876971 Amino acid sequence of protein isolated from insects which suck the blood of mammals; anticoagulants; treatment of thromboses or unstable angina or arteriosclerosis; prevention of reblockage of vessels after angioplasty
03/02/1999US5876969 Fusion polypeptide of therapeutic polypeptides attatched to c-and n-terminals of human serum albumin; for high plasma stability, minimization of dosage, side effect reduction
03/02/1999US5876968 Mixture of disulfide bonded dimer of al-milano, lipid lowering agent, and carrier; drug for treatment of athlerosclerosis and cardiovascular disease; prodrug for monomer; prevention of thrombosis
03/02/1999US5876967 Fibroblast growth factor homologous factor-2 and methods of use
03/02/1999US5876966 Compounds and methods for the stimulation and enhancement of protective immune responses and IL-12 production
03/02/1999US5876965 Nucleic acid encoding ARF-19, a novel regulator of the mammalian cell cycle
03/02/1999US5876964 Nucleotide sequence encoding enzyme from peppermint species; for recombinant expression systems to enhance production of monoterpenoids in plants; anticancer agents for gene therapy
03/02/1999US5876963 Human nucleotide pyrophosphohydrolase
03/02/1999US5876961 Production of antibodies
03/02/1999US5876958 Assays of cells expressing human calcium channels containing α1 β subunits
03/02/1999US5876951 Yeast cells engineered to produce pheromone system protein surrogates and uses therefor
03/02/1999US5876950 Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy
03/02/1999US5876943 Antigenic polypeptide produced by genetic engineering for use in diagnosis of and vaccines to peptic ulcers and stomach cancer
03/02/1999US5876940 Assay offers a powerful option for the diagnosis of many genetic diseases.
03/02/1999US5876939 Screening for apoptosis modulators by determining alteration of association between cytoplasmic domain of cell surface protein and other proteins in presence of compound; anticarcinogenic agents
03/02/1999US5876938 Use of boron-containing polynucleotides as diagnostic agents
03/02/1999US5876937 Method for determining the integrity of nucleic acid
03/02/1999US5876936 Nucleic acid sequencing with solid phase capturable terminators
03/02/1999US5876934 DNA sequencing method
03/02/1999US5876932 Method for gene expression analysis
03/02/1999US5876931 Identification of genes
03/02/1999US5876930 Detecting polynucleotide in sample using oligonucleotide probe containing fluorescence and quencher molecules; probe has different conformations allowing different signal intensities when hybridized or unhybridized
03/02/1999US5876929 Analysis kit identifying dna, distinguishes between different eukaryotic sources; enzyme digest of driver dna and tester dna with target dna, ligate adaptors, amplify, melt, anneal of amplicons, use as probes to screen cells
03/02/1999US5876925 Generating bacteriophage display library expressing heterologous protein which bonds antigen on magnetically labeled cells; incubating with labeled and unlabeled cells, separating out label cells, isolating dna
03/02/1999US5876924 Detecting target nucleic acids by hybridization with oligonucleotide-ligand probe; forming complex with target, probes and paramagnetic beads; separating and washing complex; circularizing probes forming detectable cluster
03/02/1999US5876923 Screening suppressors which inhibit infected cell protein-4 polypetide by infecting cells with defective alpha-4 gene virus, incubating with compound allowing viral replication, comparing cell pathology
03/02/1999US5876919 Incubating compound with tub protein in vitro, detection of complex formed; for modulators of obesity, cachexia, and other eating disorders
03/02/1999US5876734 Polypeptides for diagnosing infection with Trypanosoma cruzi
03/02/1999US5876731 Candidate vaccines against hiv-1 and which are useful in diagnostic application.
03/02/1999US5876730 Heparin-binding growth factor (HBGF) polypeptides
03/02/1999US5876725 Actinobacillus pleuropneumoniae transferrin binding protein vaccines and uses thereof
03/02/1999US5876723 Purified human papillomavirus type 33 (HPV-33) peptides as an immunogenic composition
03/02/1999US5876722 Hybrid protein
03/02/1999US5876718 Using antibodies which bind to protein
03/02/1999US5876717 Prevent rejection of organ transplantation and also to cure autoimmune diseases.
03/02/1999US5876713 Glutamine: fructose-6-phosphate amidotransferase, its production and use
03/02/1999US5876712 Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated