| Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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| 04/18/2000 | US6051430 Vectors and methods for providing cells with additional nucleic acid material integrated in the genome of said cells |
| 04/18/2000 | US6051429 Peptide-enhanced cationic lipid transfections |
| 04/18/2000 | US6051428 Transducing tumor cells with herpes simplex virus amplicon containing gene coding for cytokines, chemokines, cellular adhesion molecules, or costimulatory molecules which activate b or t-cells for transient expression of the protein |
| 04/18/2000 | US6051427 Retroviral packaging plasmid including retroviral helper dna lacking native enhancer and/or promoter of the viral 5' long terminal repeat, the psi function sequence and the 3' long terminal repeat, but encodes foreign regulatory sequences |
| 04/18/2000 | US6051426 Vector includes dna sequences encoding pre-s and s region of hepatitis b genome under control of heterologous promoter; for use in chinese hamster ovary cells to produce vaccines having immunogenic properties of hepatitis b surface antigen |
| 04/18/2000 | US6051424 Human cDNAs and proteins encoded thereby |
| 04/18/2000 | US6051419 Genes which influence pichia proteolytic activity, and uses therefor |
| 04/18/2000 | US6051418 Hybrid proteins with modified activity |
| 04/18/2000 | US6051410 Self-assembled, defective, nonself-propagating viral particles |
| 04/18/2000 | US6051409 Method for achieving integration of exogenous DNA delivered by non-biological means to plant cells |
| 04/18/2000 | US6051408 Gene and gene structure coding for an aminotransferase, and microorganisms which express this gene |
| 04/18/2000 | US6051407 A dna encoding a protein; regulating the production of cellulose in prokaryotic and eukaryotic cells |
| 04/18/2000 | US6051406 Keratan sulfate 6-sulfotransferase and DNA coding for the same |
| 04/18/2000 | US6051405 An expression vector containing a dna segment that directs the synthesis of a recombinant fusion protein which is a single chain fab variable region from a modified pseudomonas exotoxin gene; producing improved toxins |
| 04/18/2000 | US6051404 A nucleic acid encoding a protein; vaccines for poultry |
| 04/18/2000 | US6051402 A nucleic acid encoding an anti-sickling beta-globin protein; gene therapy for sickle cell |
| 04/18/2000 | US6051401 Methods and constructs for protein expression |
| 04/18/2000 | US6051400 An expression system comprising of a polynucleotide encoding a protein; therapy and diagnosis of kidney diseases, cardiovascular disorders, strokes, alzheimer's disease; anticarcinogenic agents and antiinflammatory agents |
| 04/18/2000 | US6051399 Production of C-terminal amidated peptides from recombinant protein constructs |
| 04/18/2000 | US6051398 Nucleic acids encoding CR3 polypeptide, vector and transformed cell thereof, and expression thereof |
| 04/18/2000 | US6051397 DNA encoding MCK-10, a novel receptor tyrosine kinase |
| 04/18/2000 | US6051396 Method for producing retinoblastoma gene protein products |
| 04/18/2000 | US6051387 Methods of determining the presence of a neoplasm with CLNH5- and CLNH11-specific antibodies |
| 04/18/2000 | US6051386 Introducing a stimulant to test cells of a pigment cell line expressing exogenous cell surface receptor to set an initial state of pigment disposition, contacting with test chemical; change in pigment disposition indicates an agonist |
| 04/18/2000 | US6051385 Compositions and methods for identifying and testing therapeutics against HSV infection |
| 04/18/2000 | US6051384 Method of detecting p53-specific antibodies |
| 04/18/2000 | US6051383 Protein from pseudomonas fluorescens involved in antibiotic biosynthesis; for transformed bacteria that are useful as agricultural biocontrol agents against fungal pathogens |
| 04/18/2000 | US6051382 Process for recognizing the risk of becoming ill after an arthropod bite |
| 04/18/2000 | US6051381 Escherichia host cell containing a fusion protein, a dna binding domain, protein interacting domain, and a reporter gene linked to a promoter; used as a yeast two-hybrid system; interaction cloning, mapping/analyzing protein interactions |
| 04/18/2000 | US6051380 Hybridizing dna in an electrophoresis system using a low conductivity, zwitterionic buffer; transporting dna toward a microlocation where ph of buffer is below the isoelectric point, enhancing hybridization of dna to probe |
| 04/18/2000 | US6051379 Oligonucleotides capable of detecting mutations in a tumor suppressor gene at specific locations using an allele specific detection assay; for detection possible development of breast and ovarian cancer |
| 04/18/2000 | US6051376 Uses of mda-6 |
| 04/18/2000 | US6051375 Glycoprotein B of the RFHV/KSHV subfamily of herpes viruses |
| 04/18/2000 | US6051373 Methods for screening for inhibitors of the transcription-enhancing activity of the X protein of hepatitis B virus |
| 04/18/2000 | US6051239 Compositions and methods for systemic delivery of oral vaccines and therapeutic agents |
| 04/18/2000 | US6051237 Specific immunotherapy of cancer using a live recombinant bacterial vaccine vector |
| 04/18/2000 | US6051232 Comprising allogenic chimeric major histocompatibility complex class i milecule; to induce tolerance to donor grafts when administered to the recipient at time of transplantation |
| 04/18/2000 | US6051229 Human-human hybridom for neoplasms CLNH5 and CLNH11 specific antibody compositions |
| 04/18/2000 | US6051228 Antibodies against human CD40 |
| 04/18/2000 | US6051227 Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
| 04/18/2000 | US6051226 use of antibodies targeting the MN oncoprotein conjugated to an anticancer therapeutic agent such as drug or toxin for tissue targeted cancer therapy |
| 04/18/2000 | US6051225 Family of high affinity, modified antibodies for cancer treatment |
| 04/18/2000 | US6051222 Cancer diagnosis; genetic engineering |
| 04/18/2000 | US6051221 BRK protein tyrosine kinase and encoding nucleic acid |
| 04/18/2000 | US6051218 Administering cell expressing interleukin-3 |
| 04/18/2000 | US6051217 Administering to patient with hematopoietic or immunodeficiency |
| 04/18/2000 | CA2192184C Extraction of heterologous insoluble proteins from bacteria |
| 04/18/2000 | CA2156176C Dna polymerases with enhanced thermostability and enhanced length and efficiency of primer extension |
| 04/18/2000 | CA2092195C Retroviral packaging cell line |
| 04/18/2000 | CA2076068C Method and apparatus for inducing controlled stressed behavior in animals, such as enhanced eating, drinking, mating, maternal or the like behavior |
| 04/18/2000 | CA1340963C Gene for encoding a human malaria vaccine antigen |
| 04/17/2000 | CA2284849A1 Episomally replicating vector, its preparation and use |
| 04/16/2000 | CA2284857A1 G protein coupled receptor a4 |
| 04/13/2000 | WO2000020867A1 A novel ret-independent signaling pathway for gdnf |
| 04/13/2000 | WO2000020645A1 ANTISENSE OLIGONUCLEOTIDE MODULATION OF TUMOR NECROSIS FACTOR-α (TNF-α) EXPRESSION |
| 04/13/2000 | WO2000020642A1 Prevention of adhesions |
| 04/13/2000 | WO2000020640A1 A novel method of diagnosing, monitoring, staging, imaging and treating gastrointestinal cancers |
| 04/13/2000 | WO2000020639A1 Enzymatic synthesis of oligonucleotide tags |
| 04/13/2000 | WO2000020636A1 Methods of identifying inverse agonists of the serotonin 2a receptor |
| 04/13/2000 | WO2000020635A1 ANTISENSE MODULATION OF INTEGRIN α4 EXPRESSION |
| 04/13/2000 | WO2000020634A1 Methods for treating or identifying a subject at risk for a neurological disease by determining the presence of a variant gpiiia and/or variant gpiib allele |
| 04/13/2000 | WO2000020633A1 Detection of nucleic acid polymorphism |
| 04/13/2000 | WO2000020632A1 Susceptibility locus for osteoarthritis |
| 04/13/2000 | WO2000020631A1 Susceptibility locus for osteoarthritis |
| 04/13/2000 | WO2000020630A1 Oligonucleotide primers that destabilize non-specific duplex formation and uses thereof |
| 04/13/2000 | WO2000020622A1 Zinc finger peptide cleavage of nucleic acids |
| 04/13/2000 | WO2000020621A1 Extracellular novel rage binding protein (en-rage) and uses thereof |
| 04/13/2000 | WO2000020619A2 Secreted renilla luciferase |
| 04/13/2000 | WO2000020617A1 Intercellular propagation of recombinant dna |
| 04/13/2000 | WO2000020616A1 HYPERSENSITIVE RESPONSE ELICITOR FROM $i(XANTHOMONAS CAMPESTRIS) |
| 04/13/2000 | WO2000020615A2 Commercial production of laccase in plants |
| 04/13/2000 | WO2000020614A1 Geminivirus resistant transgenic plants |
| 04/13/2000 | WO2000020613A1 Plant promoters and plant terminators |
| 04/13/2000 | WO2000020612A2 Therapeutically active proteins in plants |
| 04/13/2000 | WO2000020611A1 Improved transformation of plastids |
| 04/13/2000 | WO2000020610A1 Disruption of the kex1 gene in pichia and methods of full length protein expression |
| 04/13/2000 | WO2000020609A2 Protective recombinant haemophilus influenzae high molecular weight proteins |
| 04/13/2000 | WO2000020608A1 Method of treating prostate cancer with an adenovirus expression vector encoding a prodrug enzyme |
| 04/13/2000 | WO2000020607A2 Chimaeric proteins between members of tgf-beta superfamily |
| 04/13/2000 | WO2000020606A1 Method for the production of (poly)peptides by using truncated variants of the sv40 large t antigen with an intact n terminus |
| 04/13/2000 | WO2000020605A1 Sulfotransferase sequence variants |
| 04/13/2000 | WO2000020604A2 Oxidoreductase molecules |
| 04/13/2000 | WO2000020603A1 Altered fatty acid biosynthesis in insect cells using delta five desaturase |
| 04/13/2000 | WO2000020602A2 Delta 6 and delta 12 desaturases and modified fatty acid biosynthesis and products produced therefrom |
| 04/13/2000 | WO2000020601A2 Polyketide synthase enzymes and recombinant dna constructs therefor |
| 04/13/2000 | WO2000020600A1 Avian pneumovirus vaccine and diagnostic agent |
| 04/13/2000 | WO2000020599A1 Established cells |
| 04/13/2000 | WO2000020598A1 Peptides useful for reducing symptoms of toxic shock syndrome and septic shock |
| 04/13/2000 | WO2000020597A1 Novel strains of the bacillus subtilis group for food fermentation |
| 04/13/2000 | WO2000020596A1 Fungal transcriptional activator useful in methods for producing polypeptides |
| 04/13/2000 | WO2000020595A1 Interleukin-1 homolog |
| 04/13/2000 | WO2000020594A1 Tsg-5: a tnf-inducible gene |
| 04/13/2000 | WO2000020593A1 Il-17 homolog nucleic acids, polypeptides, vectors, host cells, methods and uses thereof |
| 04/13/2000 | WO2000020592A1 Glucose-dependent insulinotropic peptide for use as an osteotropic hormone |
| 04/13/2000 | WO2000020591A2 Tgf-beta superfamily mutant members, including morphogenic proteins |
| 04/13/2000 | WO2000020590A2 G-protein coupled receptor proteins |
| 04/13/2000 | WO2000020589A2 PTANs: TESTIS SPECIFIC PROTEINS EXPRESSED IN PROSTATE CANCER |
| 04/13/2000 | WO2000020588A2 Bone marrow-derived serum proteins |
| 04/13/2000 | WO2000020587A2 Cancer associated antigens and uses therefor |
| 04/13/2000 | WO2000020586A2 Renal cancer associated antigens and uses therefor |