Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
04/2000
04/20/2000DE19848129A1 New nucleic acid sequence encoding Alcaligenes faecalis nitrilase polypeptide useful for converting racemic nitriles to chiral carboxylic acids
04/20/2000DE19848017A1 Episomally replicating vectors, useful in gene therapy, contain origins of replication and scaffold-matrix attached region sequences but no viral coding sequences
04/20/2000DE19848016A1 Production of extracellular microbial protein, particularly esterolytic enzymes, in heterologous bacteria transformed with appropriate nucleic acid and secretory apparatus
04/20/2000DE19847690A1 Diagnosing sepsis and severe infections, useful for assessing severity and progress of treatment, by measuring content of peptide prohormone or their derived fragments
04/20/2000DE19847628A1 Outer membrane protein of Helicobacter pylori and DNA sequences, useful in vaccines and for production of diagnostic or therapeutic antibodies
04/20/2000DE19847064A1 Mutant AMPA-type glutamate receptor, useful for identifying receptor agonists and antagonists, lacks the desensitizing properties of the wild-type receptor
04/20/2000DE19846499A1 Production of microorganisms that overproduce pantothenic acid, useful as vitamin in e.g. foods or medicines, by overexpressing sequences that encode ketopantothenate reductase
04/20/2000DE19844111A1 Novel antisense nucleic acids targeted to specific sequences within the ICAM-1 gene, useful for treating inflammation and metastasis
04/20/2000CA2675802A1 Use of an immunoglobulin-producing cell line to gererate diversity in a gene or gene product
04/20/2000CA2356613A1 Improved hybridisation assay in which excess probe is destroyed
04/20/2000CA2348688A1 Non-endogenous, constitutively activated human g protein-coupled receptors
04/20/2000CA2347968A1 Follistatin-related protein zfsta2
04/20/2000CA2347653A1 Novel cell signaling polypeptides and nucleic acids
04/20/2000CA2347247A1 Genes for assessing cardiovascular status and compositions for use thereof
04/20/2000CA2347121A1 (mbp1) polypeptides capable of interacting with oncogenic mutants of the p53 protein
04/20/2000CA2347113A1 Human ankyrin family protein
04/20/2000CA2347091A1 Method and apparatus for direct in vivo gene transfer by electrotransfecection
04/20/2000CA2346877A1 Specific genetic modification of the activity of trehalose-6-phosphate synthase and expression in a homologous or heterologous environment
04/20/2000CA2346776A1 Non-desensitizing ampa-receptors
04/20/2000CA2346775A1 Protein kinase homologs
04/20/2000CA2346743A1 Metabolic selection methods
04/20/2000CA2346713A1 Neisseria genomic sequences and methods of their use
04/20/2000CA2346501A1 Method for amplifying foreign genes
04/20/2000CA2346499A1 Dna sequences for enzymatic synthesis of polyketide or heteropolyketide compounds
04/20/2000CA2346364A1 Method for determining transcription factor activity and its technical uses
04/20/2000CA2346263A1 Nucleic acids that control reproductive development in plants
04/20/2000CA2346259A1 Means and methods for modulating stomata characteristica in plants
04/20/2000CA2346155A1 Enzymatic synthesis of ssdna
04/20/2000CA2346122A1 Stabilized bioactive peptides and methods of identification, synthesis and use
04/20/2000CA2346008A1 G-protein-coupled receptor-like proteins, polynucleotides encoded by them, and methods of using same
04/20/2000CA2346006A1 Delta 6 fatty acid desaturase
04/20/2000CA2346004A1 Transformation process
04/20/2000CA2345936A1 Production of ssdna in a cell
04/20/2000CA2345904A1 Nucleic acid molecules encodeing a branching enzyme from bacteria of the genus neisseria as well as methods for the production of .alpha.-1,6-branched .alpha.-1,4-glucans
04/20/2000CA2345900A1 Selectively replicating viral vectors
04/20/2000CA2345885A1 Bone morphogenic protein-induced genes and polypeptides, and their use in diagnostic and therapeutic methods
04/20/2000CA2345438A1 Microarray system and process for performing biochemical reactions
04/20/2000CA2345352A1 Improved method for more efficient electroporation
04/20/2000CA2345211A1 Recombinant e1a deleted adenoviral vectors
04/20/2000CA2345046A1 Materials and methods for the modification of plant cell wall polysaccharides
04/20/2000CA2344990A1 Materials and methods for the modification of plant lignin content
04/20/2000CA2344978A1 Genes, proteins and biallelic markers related to central nervous system disease
04/20/2000CA2344711A1 Expression and secretion of icil-1 receptor antagonist type ii
04/20/2000CA2344465A1 Methods and compositions for inhibiting neoplastic cell growth
04/20/2000CA2343356A1 Methods for the production of antibodies to specific regions of cyclosporine and cyclosporine metabolites
04/20/2000CA2342314A1 Non-endogenous, constitutively activated human g protein-coupled receptors
04/20/2000CA2326675A1 Isolated peptides which bind to hla-b35 molecules
04/20/2000CA2314004A1 Matrix-remodeling genes
04/19/2000EP0994192A2 Transformation cassette for yeast
04/19/2000EP0994191A1 System for expressing hyperthermostable protease
04/19/2000EP0994190A2 DNA conferring L-homoserine resistance to bacteria, and its use
04/19/2000EP0994189A1 Methods for producing L-aspartic acid crystals
04/19/2000EP0994188A1 Method for obtaining active beta-NGF
04/19/2000EP0994186A1 Raffinose synthetase gene, process for producing raffinose, and transformed plant
04/19/2000EP0993469A1 COMPOUNDS ENCODING THE PROTECTIVE M-LIKE PROTEIN OF $i(STREPTOCOCCUS EQUI) AND ASSAYS THEREFOR
04/19/2000EP0993468A1 Compositions and methods for activating genes of interest
04/19/2000EP0821730A4 Chimeric receptors for regulating cellular proliferation and effector function
04/19/2000EP0807186B1 Methods for the isothermal amplification of nucleic acid molecules
04/19/2000EP0789711B1 Identification of the p21-waf1 -pcna interaction site and therapeutic applications thereof
04/19/2000EP0785941B1 Porphyrin labeling of polynucleotides
04/19/2000EP0677109B1 Expression system for producing apolipoprotein ai-m
04/19/2000EP0667872B1 Mutant interleukin 6 with improved biological activity over wild interleukin 6
04/19/2000EP0598840B1 Human calcium channel compositions and methods
04/19/2000EP0558676B1 Process for transforming monocotyledonous plants
04/19/2000EP0550561B1 Purification of cytokeratin fragments
04/19/2000EP0222835B2 Oral vaccines
04/19/2000CN1251136A Plant with modified growth
04/19/2000CN1251135A System for in vitro transportation using modified TN5 transposase
04/19/2000CN1251134A Neurotrophic factor NNT-1
04/19/2000CN1251133A Bi or multifunctional molecules based on dendroaspin scaffold
04/19/2000CN1251132A Variants of ciliary neurotrophic factor with enhanced receptor selectivity and method for their selection
04/19/2000CN1251131A Enhancement of growth in plant
04/19/2000CN1251130A Isolated viable parasate intestinal cells
04/19/2000CN1251108A Beta-ketoacyl-acp-synthetase II enzyme and gene encoding same
04/19/2000CN1251042A Identification of broadly reactive DR restricted epitopes
04/19/2000CN1250667A Process for preparing genetically engineered polypeptide medicine with Chinese-medicinal materials as main raw material
04/19/2000CN1051576C Prodn. of plant resistant to attacks by sclerotinia sclerotiorum by introduction of gene encoding oxalate oxidase
04/18/2000US6051760 Synthetic DNA sequence having enhanced insecticidal activity in maize
04/18/2000US6051758 Recombinant sweet protein mabinlin
04/18/2000US6051757 Transforming dicotyledonous plant by contacting with agrobacterium tumefaciens having a gene vector comprising exogenous dna but not a functional cytokinin autonomy gene
04/18/2000US6051756 Rapid, simple and efficient process by treating cells prepared from non-embryo brassica tissue with microprojectiles coated with nucleic acid, then identifying stable transformants
04/18/2000US6051755 Modification of plant lipids and seed oils utilizing yeast SLC genes
04/18/2000US6051754 Nucleic acid construct including a nucleotide sequence encoding a polypeptide which desaturates a fatty acid at carbon 5 from the carboxyl end and operably associated with regulatory sequences for gene expression in plants
04/18/2000US6051753 For use in genetic engineering constructs for gene expression of heterologous proteins in plants
04/18/2000US6051719 Dibenzorhodamine dyes
04/18/2000US6051699 Process for the synthesis of oligomeric compounds
04/18/2000US6051698 Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
04/18/2000US6051697 Chemokine expressed in eosinophils
04/18/2000US6051696 Process for typing of HCV isolates
04/18/2000US6051693 Human monoclonal antibody which preferentially binds to neoplastic cell over a normal cell of same tissue type; for diagnosis, anticarcinogenic agents and antitumor agents
04/18/2000US6051692 Amino acid sequence; for prevention, treatment and diagnosis of disorders associated with cellular development and differentiation and retinoid metabolism; vision defects; skin disorders; urogenital disorders; addison's disease
04/18/2000US6051691 Amino acid sequence of protein; for screening bactericides and bacteristats especially targeted to streptococci
04/18/2000US6051689 Receptor for the glucagon-like-peptide (GLP-1)
04/18/2000US6051688 Amino acid sequence for polypeptide of at least 6 contiguous amino acids; for diagnosis and treatment of nervous system disorders; anticonvulsants; antiischemic/antihypoxic agents; antiepileptic agents; alzheimer's/parkinson's diseases
04/18/2000US6051686 Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
04/18/2000US6051636 Denaturing solvent for electrophoresis of nucleic acids comprising an entangled polymer formed by a linear polymer; and a denaturant selected from n-alkyl pyrrolidinone, delta-valerolactam, n-methylcaprolactam and lactone
04/18/2000US6051559 Cloning and characterizing of genes associated with long-term memory
04/18/2000US6051556 Hybrid pesticidal toxins
04/18/2000US6051550 Materials and methods for controlling homopteran pests
04/18/2000US6051431 Selection marker gene free recombinant strains: a method for obtaining them and the use of these strains