Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
08/2000
08/08/2000US6100388 Lactobacilli harboring aggregation gene as a vaccine delivery vehicle
08/08/2000US6100387 Chimeric polypeptides containing chemokine domains
08/08/2000US6100386 Nucleotide sequences coding polypeptide associated with signal transductionand tyrosine kinases; for the treatment of cancers; anticarcinogenic agents
08/08/2000US6100383 Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
08/08/2000US6100376 A21, B30, modified insulin derivatives having an altered action profile
08/08/2000US6100243 Method of sensitizing tumor cells with adenovirus E1A
08/08/2000US6100242 Gene therapies for enhancing cardiac function
08/08/2000US6100241 Nucleic acids encoding an immunogenic fragment of eimeria lactate dehydrogenase (ldh) which will react with antiserum raised against the ldh; preparing a vector vaccine against coccidiosis; administering to prevent coccidiosis in birds
08/08/2000US6100235 Methods of treating immune and inflammatory response with IL-17 receptors
08/08/2000US6100099 Chromatographic aparatus for the immunological detection of compounds; for the detection of target nucleotide sequences, antigens and antibodies
08/08/2000US6100092 Replication of target nucleic acids; transforming or transfecting cells with plant preferential regulatory sequences and propagating cells
08/08/2000US6100091 Modified acyl-ACP desaturase
08/08/2000US6100090 Compound 8 to 30 nucleobases in length targeted coding region of human phosphatidyl inositol 3'-kinase p85; therapy and diagnosis of diseases related hormone and growth factor receptors and oncogene products
08/08/2000US6100089 Using animal cell in culture which has stably integrated laci gene (the lac repressor), lac operator, and reporter gene; exposure to compound which mutates laci gene causes detectable expression of reporter gene
08/08/2000US6100088 Viral vaccines
08/08/2000US6100087 Ribozymes targeted to human CCR5 mRNA
08/08/2000US6100086 Expression construct of transgene, regulatory sequences, and adenoviral sequences; facilitates persistent expression of transgene in cells and protects cells from cell-mediated immune responses; gene therapy especially for cystic fibrosis
08/08/2000US6100079 Method for treating biopolymers, microorganisms or materials by using more than one type of magnetic particles
08/08/2000US6100078 Purified DNA polymerase from bacillus stearothermophilus ATCC 12980
08/08/2000US6100077 Isolation of a gene encoding diacylglycerol acyltransferase
08/08/2000US6100076 Amino acid sequence of enzyme which glycosylates an epidermal growth factor domain of a polypeptide with an activated fucose moiety
08/08/2000US6100074 Mutant mono-oxygenase cytochrome P-450 cam
08/08/2000US6100072 Preparing liquid or lyophilized reagent by mixing surfactant solubilized tissue factor with surfactant-free solution, suspension, or dispersion of phospholipid vessicle, incubating mixture to produce reagent; also fibrinogen levels
08/08/2000US6100071 Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production
08/08/2000US6100070 G-CSF receptor agonists
08/08/2000US6100069 Amino acid sequence of peptidyl-propyl cis/trans isomerase involved in protein folding; for screening bacteriostats, bactericides, and antibiotics; diagnosis and prophylaxis
08/08/2000US6100068 Method of protein production using mitochondrial translation system
08/08/2000US6100067 Molecules containing at least one peptide sequence carrying one or several epitopes characteristic of a protein produced by P. falciparum at the sporozoite stage and in the hepatocytes
08/08/2000US6100065 Recombinant polypeptide particles with high immunogenicity; comprises portion of pre-s1 peptide and surface antigen peptide
08/08/2000US6100064 Increasing secretion by culturing cells transformed with recombinant vector encoding cytomegalovirus gb protein that may have deactivated protease site and lacks transmembrane encoding domain but has cytoplasmic domain
08/08/2000US6100063 Procaryotic cell comprising at least two copies of a gene
08/08/2000US6100062 Expression system for HSCLOCK
08/08/2000US6100060 Recombinant expression system of polynucleotide encoding a specific amino acid sequence and present in a host cell; for recombinant production of wnt-5b polypeptides important in developmental signal transduction
08/08/2000US6100059 Compounds
08/08/2000US6100057 Introducing regulatory sequences which link to endogenous heme biosynthetic enzymes or copies of nucleotide sequences encoding heme biosynthetic enzymes with linked regulatory sequences, culturing fungus, recovering secreted hemoprotein
08/08/2000US6100056 Lactococcus which does not secrete a natural nisin, but which expresses genes for nisin modification, immunity, and translocation out of cell; for production of mutant nisins including acid stable variant
08/08/2000US6100054 Production for recombinant lactoferrin and lactoferrin polypeptides using DNA sequences in various organisms
08/08/2000US6100053 Microbial transglutaminases, their production and use
08/08/2000US6100048 Using a panel of mammalian cells transformed with recombinant expression constructs encoding a variety of melanocortin receptors; contacting cells with compound, detecting binding, and determing if compound inhibits feeding behavior
08/08/2000US6100046 Methods of identifying modulators of alpha9, a novel acetylcholine-gated ion channel receptor subunit
08/08/2000US6100043 Isolating individual cell of interest by contacting cell population with capture system of member of binding pair attached at discrete sites to solid support; complementary binding pair member is expressed on surface of host organism
08/08/2000US6100042 Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
08/08/2000US6100041 Human prohormone convertase 4
08/08/2000US6100040 Methods and compositions for detection of specific nucleotide sequences
08/08/2000US6100037 Polynucleotide encoding a cyclic nucleotide phosphodiesterase having a specific amino acid sequence; diagnosis, treatment, and prevention of cancer and immune disorders; anticarcinogenic/antidiabetic/antiarthritic agents
08/08/2000US6100035 Contacting nucleic acids bound to nucleic acid binding factors with a population of isolated nucleic acids, and identifying the isolated nucleic acids that bind to the nucleic acid binding factors
08/08/2000US6100034 Detection of retroviral subtypes based upon envelope specific sequences
08/08/2000US6100032 Human Smad3 and Smad4 are sequence-specific transcription activators
08/08/2000US6100029 Methods for the detection of chromosomal aberrations
08/08/2000US6100025 Dna encoding a mammalian cyclic nucleotide phosphodiesterase and which are inserts in plasmids ppde46 (atcc no. 69552), ppde43 (atcc no 69551), and ppde339 (atcc no. 69550)
08/08/2000US6099846 Immunocomplex; forming antibodies
08/08/2000US6099843 Used to protect animals from diseases caused by parasitic helminths
08/08/2000US6099842 Recombinant immunotoxin composed of a single chain antibody reacting with the human transferrin receptor and diptheria toxin
08/08/2000US6099841 Include hgf receptor antibodies and fragments thereof; used to treat a pathological liver condition
08/08/2000US6099840 Variant hbsag protein of fragment thereof displaying the antigenicity of hepatitis b virus surface antigen
08/08/2000US6099838 For the prevention or reversal of transplant rejection as well as therapy for autoimmune diseases
08/08/2000US6099832 Transplants for myocardial scars
08/08/2000US6099831 Recombinant vectors of viral origin which contain a nucleotide sequence coding for a specific polypeptide, and their use for the expression of this polypeptide in muscle cells; used as medicines in the field of muscle diseases
08/08/2000US6099823 Compositions and methods for the treatment and diagnosis of cardiovascular disease
08/08/2000CA2233144C Arf-p19, a novel regulator of the mammalian cell cycle
08/08/2000CA2219795C Modulation of cholesteryl ester transfer protein (cetp) activity
08/08/2000CA2216165C Ndf peptides
08/08/2000CA2207505C Neurological drug screens
08/08/2000CA2176746C Nucleic acid analogue induced transcription of double stranded dna
08/08/2000CA2149764C Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
08/08/2000CA2071907C Bcrf1 proteins as inhibitors of interferon-y
08/08/2000CA2070664C Antisense oligonucleotide inhibition of papillomavirus
08/08/2000CA2067711C Solid phase extraction purification of dna
08/08/2000CA1341082C Method of treating tumor cells by inhibiting growth factor receptor function
08/08/2000CA1341079C Large scale method for purification of high purity heparinase
08/08/2000CA1341074C Hbv surface antigen particles, prepared by recombinant dna processes, composed of different epitopes, selected from the pre-s and s-peptides as a new vaccine
08/08/2000CA1341073C Vectors and methods for expression of human protein c activity
08/05/2000CA2297352A1 Multiplex genotyping of populations of individuals
08/03/2000WO2000045322A1 Determining protein function and interaction from genome analysis
08/03/2000WO2000045177A1 Assays for modulators of elongation factor p activity
08/03/2000WO2000045176A2 METHOD OF IDENTIFYING N-TERMINAL proBNP
08/03/2000WO2000045167A2 Non-invasive method for detecting target rna
08/03/2000WO2000045146A1 Array centrifuge
08/03/2000WO2000044940A2 Nucleic acid sequences for detecting genetic markers for cancer in a biological sample
08/03/2000WO2000044939A1 Replicable probe array
08/03/2000WO2000044936A1 Microassay for serial analysis of gene expression and applications thereof
08/03/2000WO2000044935A2 Multiplex real-time pcr
08/03/2000WO2000044934A2 Method of identifying cytosine methylation patterns in genomic dna samples
08/03/2000WO2000044926A1 High level expression of a heterologous protein having rare codons
08/03/2000WO2000044923A1 Biocatalytic synthesis of shikimic acid
08/03/2000WO2000044922A1 E1b-deleted adenoviral shuttle vectors
08/03/2000WO2000044921A1 Transgenic plants modified to contain resveratrol glucoside and uses thereof
08/03/2000WO2000044920A1 Maize alternative oxidase genes and uses thereof
08/03/2000WO2000044919A1 Transformation and regeneration of allium plants
08/03/2000WO2000044918A1 Methods and means for modification of plant characteristics using the vernalization gene vrn2
08/03/2000WO2000044917A1 Inducible expression system for use in plants
08/03/2000WO2000044916A1 Nucleotide sequence having a tissue specific regulatory activity on the transcription of genes in plants
08/03/2000WO2000044915A1 Method for conveying bnyvv resistance to sugar beet plants
08/03/2000WO2000044914A1 Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna
08/03/2000WO2000044913A1 Metalloprotease polynucleotides and polypeptides
08/03/2000WO2000044912A1 Manipulating isoprenoid expression
08/03/2000WO2000044911A1 Overexpression of a dna sequence coding for a transketolase in plants
08/03/2000WO2000044910A1 Methods of use of a novel lysyl oxidase-related protein
08/03/2000WO2000044909A1 Nucleic acid sequences encoding isoflavone synthase
08/03/2000WO2000044908A2 Comp/tsp-1, comp/tsp-2 and other tsp chimeric proteins