| Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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| 08/22/2000 | US6107463 Amino acid sequence of protein involved in bacterial two component signal transduction systems; bactericides and bacteriostats especially against staphylococcus |
| 08/22/2000 | US6107462 Amino acid sequences of 3-hydroxy-3-methylglutaryl-coenzyme a reductase degradation polypeptides; for screening drugs |
| 08/22/2000 | US6107457 Bcr-abl peptide having tyrosine from position 177 and/or tyrosine from position 283; suppresses induction of ras protein; anticarcinogenic agents for leukemia; enriching bone marrow stem cells prior to transplantation |
| 08/22/2000 | US6107324 5-HT2A receptor inverse agonists |
| 08/22/2000 | US6107287 Killing tumor cells |
| 08/22/2000 | US6107286 Complexing with nucleic acids |
| 08/22/2000 | US6107279 Class of proteins for the control of plant pests |
| 08/22/2000 | US6107278 Polynucleotide encoding lepidopteran active toxin PS86I2 derived from Bacillus thuringiensis and methods of using PS86I2 |
| 08/22/2000 | US6107265 Detergent compositions containing cellulase compositions deficient in CBH I type components |
| 08/22/2000 | US6107104 Calcineurin deletion mutant which binds a-kinase anchor protein 79 and having defined amino acid sequence; for screening enzyme inhibitors for use as immunosuppressants with reduced side effects |
| 08/22/2000 | US6107095 Low cost, efficient delivery; dispersing liquid containing substance into microdroplets which penetrate without destroying cells by using rotating vessel which ejects liquid through peripheral openings toward cells |
| 08/22/2000 | US6107094 In vitro modification of target rna by contacting solution of target and ribonuclease preferential for double-stranded rna with oligonucleotide complementary to target and including nucleotides modified to improve affinity/specificity |
| 08/22/2000 | US6107093 Recombinant cells that highly express chromosomally-integrated heterologous genes |
| 08/22/2000 | US6107092 Compound 8 to 30 nucleobases in length targeted to human steroid receptor rna activtor or nucleic acid encoding the activator; for decreased amount or function; therapy and prophylaxis of related diseases |
| 08/22/2000 | US6107091 Compound 8 to 30 nucleobases in length targeted to 5' or 3' untranslated regions or coding region of a nucleic acid encoding human g protein; diagnosis, prophylaxis and therapy of related diseases |
| 08/22/2000 | US6107090 Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains |
| 08/22/2000 | US6107089 Nucleic acids encoding annexin XI |
| 08/22/2000 | US6107088 XAF genes and polypeptides: methods and reagents for modulating apoptosis |
| 08/22/2000 | US6107087 High level expression of human cyclooxygenase-2 |
| 08/22/2000 | US6107086 Determined DNA sequences derived from a papillomavirus genome, their uses for in vitro diagnostic purposes and the production of antigenic compositions |
| 08/22/2000 | US6107078 Ribozymes with optimized hybridizing arms, stems, and loops, tRNA embedded ribozymes and compositions thereof |
| 08/22/2000 | US6107076 Activated by g-protein, g-s-alpha; for screening stimulators and enzyme inhibitors |
| 08/22/2000 | US6107075 Human elastase IV |
| 08/22/2000 | US6107074 TRAF2-associated protein kinase and assays |
| 08/22/2000 | US6107073 Kinase capable of site-specific phosphorylation of IκBα |
| 08/22/2000 | US6107072 Thermostable geranylgeranyl diphosphate synthase |
| 08/22/2000 | US6107071 Polynucleotide or complementary sequence which codes for a specific staphylococcus aureus amino acid sequence; for diagnosis of bacterial infections; screening of bactericides, bacteriostats, and antibiotics |
| 08/22/2000 | US6107070 Human manganese superoxide dismutase proteins |
| 08/22/2000 | US6107069 Nucleotide and amino acid sequences; for cloning; for hybridization probes to screen libraries |
| 08/22/2000 | US6107063 Recombinantly preparing microorganism with mutated enzyme by replacing at least one base in region which codes for allosteric domain causing reduced l-isoleucine feedback inhibition, and culturing microorganism |
| 08/22/2000 | US6107062 Antisense viruses and antisense-ribozyme viruses |
| 08/22/2000 | US6107061 Modified primer extension reactions for polynucleotide sequence detection |
| 08/22/2000 | US6107060 Starch encapsulation |
| 08/22/2000 | US6107059 Peptide library and screening method |
| 08/22/2000 | US6107057 Polynucleotide sequence coding leader sequences of killing antigen and a somatomedin; for the production of heterologous polypeptides in yeast |
| 08/22/2000 | US6107051 Evaluation of propagation capacity in plants; monitoring the amount of soluble polypeptide in endosperm |
| 08/22/2000 | US6107042 Cell-free system for initiation of DNA replication |
| 08/22/2000 | US6107041 Detecting modulators of inhibitor of apoptosis; incubating cell that expresses inhibitor of apoptosis with modulator, monitor the expression of inhibitor of apoptosis, increase in apoptosis is indicator of the presence of a modulator |
| 08/22/2000 | US6107040 Pharmacological targeting of mRNA cap formation |
| 08/22/2000 | US6107033 Quantitative analysis of bacteria in cultures; prepare oligonucleotide probes, hybridize probes with culture samples, count the number of labelled bacteria in sample |
| 08/22/2000 | US6107032 Sequence determination of nucleic acid molecule; one step amplification of both full-length and truncated copies of nucleotide sequence, generating a sequence ladder, evaluating sequence patterns to obtain the nucleotide sequence |
| 08/22/2000 | US6107031 Detecting an microorganism nucleic acids; sequencing nucleic acids in sample, comparing entire nucleotide sequence to known nucleotide sequences, detecting nucleotide sequences which are distinct from the known nucleotide sequences |
| 08/22/2000 | US6107028 Prevention of viral replication or expression; insertion of a expression vector coding ribonucleic acid preferential proteolytic enzyme into cells infected with virus |
| 08/22/2000 | US6107027 Supression of viral gene expression in cells; transducing cells with a adenovirus vector which codes a protein which has preferential proteolytic activity for ribonucleic acids |
| 08/22/2000 | US6107023 Isolating nucleotide sequences in mix; joining nucleotide linker to nucleotide sequences by ligation with subsequent amplification, denaturation and hybridization of nucleotide sequences, isolating preferential nucleotide sequences |
| 08/22/2000 | US6106859 Stabilization of lipid:DNA formulations during nebulization |
| 08/22/2000 | US6106843 Process for the isolation of a nontoxinogenic vibrio cholerae strain and a process for preparing cholera vaccine from said vibrio cholerae strain |
| 08/22/2000 | US6106834 Use of anti-CD45 leukocyte antigen antibodies for immunomodulation |
| 08/22/2000 | US6106833 Bispecific antibodies, methods of production and use thereof |
| 08/22/2000 | US6106832 Treating x-linked hyper igm syndrome and combined variable immunodeficiency syndrome |
| 08/22/2000 | US6106829 Diagnostic cancer marker; hybridization; vaccines |
| 08/22/2000 | US6106827 Gene expression controlled by promoter for glial fibrillary acidic protein or rsv promoter |
| 08/22/2000 | US6106826 Replication competent, avirulent Herpes simplex virus as a vector for neural and ocular gene therapy |
| 08/22/2000 | US6106825 Gene expression |
| 08/22/2000 | US6106824 Expression of growth associated protein B-50/GAP-43 in vitro and in vivo |
| 08/22/2000 | CA2297438A1 .beta..beta.-carotene 15,15'-dioxygenases |
| 08/22/2000 | CA2160784C Ligase chain reaction with endonuclease iv correction and contamination control |
| 08/22/2000 | CA2050343C Matrix metalloproteinase peptides: role in diagnosis and therapy |
| 08/22/2000 | CA2046900C Melanin-concentrating hormones and methods of treatment using same |
| 08/22/2000 | CA2016627C Proteinase inhibitors, process for the preparation thereof and medicaments containing these |
| 08/22/2000 | CA1341089C Non-a, non-b hepatitis virus antigen peptide |
| 08/22/2000 | CA1341088C Inhibition of htlv-iii by exogenous oligonucleotides |
| 08/20/2000 | CA2299105A1 Process for the fermentative production of l-amino acids using coryneform bacteria |
| 08/19/2000 | CA2261186A1 Expression and secretion of heterologous polypeptides from freshwater caulobacter |
| 08/17/2000 | WO2000048004A1 High throughput mass spectrometry |
| 08/17/2000 | WO2000047985A1 Apparatus and methods for high resolution separation of sample components on microfabricated channel devices |
| 08/17/2000 | WO2000047778A1 Method for maintenance and selection of episomes |
| 08/17/2000 | WO2000047777A1 Protection probes |
| 08/17/2000 | WO2000047775A1 Selection of proteins using rna-protein fusions |
| 08/17/2000 | WO2000047771A2 Biallelic markers derived from genomic regions carrying genes involved in arachidonic acid metabolism |
| 08/17/2000 | WO2000047764A2 Test kit and method for quantitatively detecting genetically modified dna in foodstuff by means of fluorescence-coupled pcr |
| 08/17/2000 | WO2000047763A1 CRYSTAL STRUCTURE OF cPLA2, AND METHODS OF IDENTIFYING AGONISTS AND ANTAGONISTS USING SAME |
| 08/17/2000 | WO2000047757A1 Method of producing a recombinant adeno-associated virus, suitable means for producing the same and use thereof for producing a medicament |
| 08/17/2000 | WO2000047756A1 Recombined porcine adenovirus based viral vaccines and vectors |
| 08/17/2000 | WO2000047755A2 Plant udp-glucose epimerases |
| 08/17/2000 | WO2000047754A1 A method for inhibiting the expression of target genes in plants |
| 08/17/2000 | WO2000047753A1 Actinomycetes-origin cyclic plasmid dna |
| 08/17/2000 | WO2000047751A1 Intein-mediated protein ligation of expressed proteins |
| 08/17/2000 | WO2000047750A2 Metalloproteases of the neprilysin family |
| 08/17/2000 | WO2000047749A1 Heat-inducible promoter |
| 08/17/2000 | WO2000047748A2 Udp-glucose modifiers |
| 08/17/2000 | WO2000047747A2 Maize glutathione-s-transferase enzymes |
| 08/17/2000 | WO2000047746A1 Process for producing coenzyme q10 |
| 08/17/2000 | WO2000047745A1 The ltr region of msrv-1 and the proteins it encodes, and probes and methods for detecting msrv-1 retrovirus |
| 08/17/2000 | WO2000047744A1 Antigen of erysipelothirx rhusiopathiae comprising an immuno-protective epitope |
| 08/17/2000 | WO2000047743A1 Neisseria meningitidis serogroup b antigen |
| 08/17/2000 | WO2000047742A1 Nac1 - a plant gene encoding a transcription factor involved in cotyledon and lateral root development |
| 08/17/2000 | WO2000047741A1 Glycosylated leptin compositions and related methods |
| 08/17/2000 | WO2000047740A2 Tnf-related proteins |
| 08/17/2000 | WO2000047739A2 Autoantigens for the diagnostic of endometriosis |
| 08/17/2000 | WO2000047738A2 Human and mouse trek-1 potassium channel protein and their use |
| 08/17/2000 | WO2000047737A1 Haemophilus influenzae rd outer membrane sequences used as vaccine |
| 08/17/2000 | WO2000047736A1 Polypeptide variants with raised heparin-binding capacity |
| 08/17/2000 | WO2000047735A2 NON-HUMAN TRANSGENIC ANIMAL WHOSE GERM CELLS AND SOMATIC CELLS CONTAIN A KNOCKOUT MUTATION IN DNA ENCODING ORPHAN NUCLEAR RECEPTOR ERRalpha |
| 08/17/2000 | WO2000047734A1 Inhibiting formation of atherosclerotic lesions |
| 08/17/2000 | WO2000047733A1 Antitumor antisense sequences directed against r1 and r2 components of ribonucleotide reductase |
| 08/17/2000 | WO2000047732A1 Method for fractionating double-stranded nucleic acids in solutions in order to obtain single-stranded nucleic acids |
| 08/17/2000 | WO2000047731A1 Protein having dna helicase activity, polynucleotide encoding the protein, antisense polynucleotide against the polynucleotide and antibody recognizing the protein |
| 08/17/2000 | WO2000047730A1 N-acetylglucosamine 2-epimerase and dna encoding the enzyme |
| 08/17/2000 | WO2000047729A1 Deglycosylated kringle 1-5 region fragments of plasminogen and methods of use |