Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
09/2002
09/11/2002CN1368551A Process for creating medicine screening system with ABC1 gene cell target to screen 3G medicine of cardiovascular disease
09/11/2002CN1368511A Human protein with cancer inhibiting function and its coding sequence
09/11/2002CN1368510A Human protein with suppression to cancer cell growth and its coding sequence
09/11/2002CN1368509A Human protein with suppression to cancer cell growth and its coding sequence
09/11/2002CN1368508A Human protein with cancer inhibiting function and its coding sequence
09/11/2002CN1368504A DNA sequence of dendrobium and method for discriminating its veriety and judging if it is true or false
09/11/2002CN1368384A Genetically engineered vaccine of MUC-1 antigen for human breast cancer
09/11/2002CN1090679C Monitoring multiple amplification reactions simultaneously and analyzing it
09/11/2002CN1090676C Expression systems utilizing autolyzing fusion proteins and novel reducing polypeptide
09/10/2002US6448476 Plants and plant cells transformation to express an AMPA-N-acetyltransferase
09/10/2002US6448475 Transgenic plants can be made that have altered tocopherol levels in their tissues for increased vitamin e supplementation
09/10/2002US6448474 Transforming a coffee plant with a vector comprising a nucleic acid sequence from a coffee fruit that codes for an rna that is sense/antisense to a coffee fruit-expressed mrna for acc oxidase; applying ethylene to fruit to ripen
09/10/2002US6448473 Construction and use of nucleic acid segments and vectors containing multiple sequences encoding members of a biosynthetic pathway for the synthesis of polylactone biopolymers
09/10/2002US6448472 Genetic and epigenetic manipulation of ABC transporters and ectophosphatases for the conference of hormone and herbicide resistance
09/10/2002US6448471 Nematode-feeding structure specific gene and its application to produce nematode resistant plants
09/10/2002US6448470 Mouse has cartilage comprising human col2a1 collagen gene but not mouse col2a1, and a normal skeletal structure
09/10/2002US6448469 Production of membrane proteins in the milk of transgenic nonhuman mammals
09/10/2002US6448468 Transgenetic mouse which comprises an inactive Peg3 gene, and the use thereof
09/10/2002US6448407 Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis
09/10/2002US6448391 Ubiquitin-lytic peptide fusion gene constructs with enhanced stability and gene expression
09/10/2002US6448390 Mutant protein allows for decreased shedding of the surface protein by suppressing precursor cleavage, while maintaining mutant envelope protein incorporation into a virion
09/10/2002US6448389 Human cytomegalovirus DNA constructs and uses therefor
09/10/2002US6448388 Polynucleotides encoding proteins sharing sequence similarity with mammalian proteases; proteases are associated with inter alia, regulating development, diabetes, obesity, infertility, modulating cellular processes, and infectious disease
09/10/2002US6448386 High molecular weight major outer membrane protein of moraxella
09/10/2002US6448382 Loading a mixture of isoforms onto a tsk sulfopropyl cation exchange chromatography column, washing with linear gradient buffer, discarding fraction comprising double clipped isoform and collecting intact and single-clipped isoforms
09/10/2002US6448381 DNA encoding heparin-binding growth factor
09/10/2002US6448379 Inhibitors to il8 receptor binding, including antibodies, that interact with the amino-terminal extracellular domain of the il8 receptor and compete with il8 and other related natural ligands, for receptor-binding.
09/10/2002US6448376 Two new proteins which appear to be new members of the e2f gene family, called e2f-5
09/10/2002US6448375 Active and inactive CC-chemokine receptor
09/10/2002US6448230 Testis expressed polypeptide
09/10/2002US6448226 Bacillus thuringiensis strains and their insecticidal proteins
09/10/2002US6448224 Antibiotics and methods of using the same
09/10/2002US6448221 By administering an adipocyte complement related protein to reduce platelet aggregation
09/10/2002US6448087 Method for determining and modifying protein/peptide solubility
09/10/2002US6448083 Contacting a mammalian cell with filamentous phage particles presenting a ligand on their surfaces, wherein a vector within the phage encodes a gene product under control of a promoter
09/10/2002US6448082 An isolated nucleic acid sequence capable of being transferred by conjugation, from a bacterium of the species lactococcus
09/10/2002US6448081 Oligonucleotides specifically hybridizable with nucleic acids encoding interleukin 12 p40 subunit
09/10/2002US6448080 Antisense modulation of WRN expression
09/10/2002US6448079 Inhibiting the expression of p38 mitogen activated protein kinase in cells or tissues comprising contacting said cells or tissues in vitro with the antisense compound
09/10/2002US6448078 Inhibiting human vpr interacting protein activity in a cell using a nucletide sequence complementary to a portion of the nucleotide sequence that encodes hvip; anticancer agent
09/10/2002US6448074 Adeno-associated virus vector for boosting immunogenicity of freshly isolated tumor cells
09/10/2002US6448073 Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
09/10/2002US6448071 Effective competitors to t cell receptors and mhc molecules normally involved in transplant rejection and autoimmune disease
09/10/2002US6448070 Recombinant plant viruses, especially their use as immunizing agents which carry antigenic sequences from mammalian or other animal pathogens and their use as a system for increased production of polypeptides of interest
09/10/2002US6448059 Methods and composition for inhibition of tRNA activities
09/10/2002US6448056 Microbial xyloglucan endotransglycosylase (XET)
09/10/2002US6448052 To convert ethyl 4-chloroacetoacetate using nadph as a coenzyme to produce ethyl (s)-4-chloro-3-hydroxybutyrate; substrate specificity, no activity to ethyl acetoacetate, specified optimal ph and temperature; enzyme from candida
09/10/2002US6448049 Starch conversion process
09/10/2002US6448048 Method for effecting site-directed mutagenesis
09/10/2002US6448047 Sample processing to release nucleic acids for direct detection
09/10/2002US6448046 Possessing enhanced stability within a host, enabling the sustained systemic transcription of a nucleotide sequence; accomplished by the use of a dual subgenomic promoter system which reduces the frequency of recombination
09/10/2002US6448043 Enterococcus faecalis EF040 and uses therefor
09/10/2002US6448042 These enzymes have been implicated in a variety of disease processes, including tumor cell invasion, tumor angiogenesis and rheumatoid arthritis
09/10/2002US6448041 Colon cancer marker
09/10/2002US6448040 Nucleic acid molecules encoding hypusine mutants having the biological activity, of inhibiting cellular proliferation
09/10/2002US6448039 Enhancer sequences for late T cell expressed genes
09/10/2002US6448037 PgsA
09/10/2002US6448036 ribB
09/10/2002US6448035 Disorders mediated by disease states associated with suppressed immune function can be treated by administering a soluble form of the negative signaling lir
09/10/2002US6448034 Production of variant nisin
09/10/2002US6448033 Incubating a sample of ribosomes obtained from a cell-free extract with plasmid dna containing a coding sequence for a protein of interest with an aminoacyl trna having fluorescent label
09/10/2002US6448032 With anti-inflammatory and antipyretic function and involved in a number of diseases such as melanoma and skin cancer
09/10/2002US6448021 Cc-chemokine receptor 2 (ccr2) bound by an antibody or functional fragment to block binding of a ligand
09/10/2002US6448019 Inhibit vascular smooth muscle cell activation and/or proliferation or enhance vascular endothelial cell activation and/or proliferation or activate estrogen responsive genes in vascular cells. vasoprotective agents are vasospecific,
09/10/2002US6448017 In vitro amplification of nucleic acid molecules via circular replicons
09/10/2002US6448014 PCR-hybridization assays specific for integrated retroviruses
09/10/2002US6448013 Quantitatively determining the amount of polynucleotides in a sample. the distinct polynucleotide targets and standard polynucleotide targets are contacted with detectable probes and independently detectable single or double stranded
09/10/2002US6448012 Method for mapping a nucleic acid
09/10/2002US6448011 Isolated nucleic acid, vectors, transformed mammalian cells and non-human transgenic animals that encode and express normal or mutant adrenergic receptor genes.
09/10/2002US6448009 Method for target site selection and discovery
09/10/2002US6448007 Functional genomic screen for post-transcriptional 5′ and 3′ regulatory elements
09/10/2002US6448006 Methods and compositions for reducing bacterial tolerance to antibacterials disinfectants and organic solvents
09/10/2002US6448005 14723 Receptor, a novel G-protein coupled receptor
09/10/2002US6448004 Electrochemiluminescence helicase assay
09/10/2002US6448002 Method to detect clinically relevant mutations of the DNA sequence of ki-ras oncogene, its use and a testkit for early diagnosis of tumors
09/10/2002US6448000 Viral growth and cellular genes that function as tumor suppressors. thus, the present invention provides nucleic acids related to and methods of reducing or preventing viral infection or cancer. the invention also provides methods of
09/10/2002US6447996 Polypeptides having galanin receptor activity, genetic material for expressing same, any recombinant cell expressing said polypeptides, and the use thereof, are disclosed.
09/10/2002US6447995 The viral vector particle content of a medium. a medium is provided and contacted with an excitation energy such that, if a viral vector particle is in the medium, an electron associated with the intrinsically fluorogenic portion of the
09/10/2002US6447994 A nucleic acid having a first nucleotide sequence encoding an infectious hepatitis c virus, a second nucleotide sequence encoding a ribozyme, and an inducible promoter operably linked to the first and second nucleotide sequences,
09/10/2002US6447993 Protecting cats from infection by a broad range of fiv strains using a multi-subtype fiv vaccine. multi-subtype fiv vaccines comprising either cell free whole virus or cell lines infected with viruses and vaccinating cats
09/10/2002US6447804 Dry solid medium for storage and analysis of genetic material
09/10/2002US6447783 Compositions comprising FGF9 and use thereof for stimulating cartilage and bone repair
09/10/2002US6447776 Monoclonal antibodies against mutant amino acid sequences generated by genetic deletions or point mutations; detection of cancer
09/10/2002US6447770 Biocontrol agents for take-all
09/10/2002US6447769 Modified tumor cells to inhibit transforming growth factor
09/10/2002US6447768 Methods of gene therapy with a DNA sequence encoding NOS
09/10/2002US6447766 Deamidated chemokines
09/10/2002US6447764 Method for isolating anionic organic substances from aqueous systems using cationic polymer nanoparticles
09/10/2002US6447723 Microarray spotting instruments incorporating sensors and methods of using sensors for improving performance of microarray spotting instruments
09/10/2002CA2234876C Positive selection vector for bacillus sp.
09/10/2002CA2128247C Vaccines based on streptokinase
09/10/2002CA2073441C Introns and exons of the cystic fibrosis gene and mutations at various positions of the gene
09/09/2002CA2375276A1 Methods to isolate gene coding and flanking dna
09/08/2002CA2380716A1 Dna vaccine using liposome-encapsulated plasmid dna encoding for hemagglutinin protein of influenza virus
09/08/2002CA2370324A1 Large circular target-specific antisense nucleic acid compounds
09/08/2002CA2363461A1 Methods for producing proteins by using cell-free protein synthesis systems
09/06/2002WO2002069369A2 Cpg-like nucleic acids and methods of use thereof
09/06/2002WO2002069232A2 Method for identification of t-cell epitopes and use for preparing molecules with reeduced immunogenicity
09/06/2002WO2002068955A1 Transgenic knockouts of bace-1
09/06/2002WO2002068927A2 Using viruses to detect or purify proteins