| Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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| 09/17/2002 | US6451765 Methods for treating breast cancer using Mammastatin |
| 09/17/2002 | US6451764 VEGF-related protein |
| 09/17/2002 | US6451760 Treatment of inflammation using a 2F1 polypeptide or an antibody thereto |
| 09/17/2002 | US6451604 Polynucleotides; nucleotide sequence and complement; genetic engineering |
| 09/17/2002 | US6451603 Ribozyme nucleic acids and methods of use thereof for controlling viral pathogens |
| 09/17/2002 | US6451602 Hybridizable oligonucleotides |
| 09/17/2002 | US6451601 Increasing the replicative capacity of normally quiescent cells, such as normal somatic cells, by transient immortalization or transient telomerization, to produce cells suitable for gene therapy |
| 09/17/2002 | US6451597 Method for enhanced protein stabilization and for production of cell lines useful for production of such stabilized proteins |
| 09/17/2002 | US6451596 Helper adenovirus vectors |
| 09/17/2002 | US6451595 Murine leukemia virus with pol, env, and gag coding regions deleted; gene therapy; gene expression and engineering |
| 09/17/2002 | US6451594 Adenovirus vector comprising transgene, cardiomyocyte restricted ankyrin repeat protein promoter, and inverted terminal repeat sequences from human adeno-associated virus |
| 09/17/2002 | US6451593 Circular strand of dna forms dumbbell; complementary sequence duplex has promoter, coding, and polyadenylation sequences; noncomplementary single-strand loops; microprojectiles for ballistic cell transfer |
| 09/17/2002 | US6451592 Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis |
| 09/17/2002 | US6451582 Staphylococcus strains comprising an inducible gene encoding an RNA polymerase specificity factor |
| 09/17/2002 | US6451581 Isolated nucleic acid fragment encoding a branched-chain biosynthetic enzyme. the invention also relates to the construction of a chimeric gene encoding all or a portion of the branched-chain biosynthetic enzyme, in sense or antisense |
| 09/17/2002 | US6451579 Regulated expression of recombinant proteins using RNA viruses |
| 09/17/2002 | US6451577 Human uridine disphosphate galactose-4-epimerase |
| 09/17/2002 | US6451576 Sesquiterpene synthases from grand fir (Abies grandis), and methods of use |
| 09/17/2002 | US6451575 The invention is directed to the family of aggrecan degrading metallo proteases (admps) that exhibit the ability to cleave the aggrecan core protein between amino acid residues glu.sup.373 -ala.sup.374. the invention encompasses the |
| 09/17/2002 | US6451574 Proteinase K variants having decreased adsorption and increased hydrolysis |
| 09/17/2002 | US6451573 Proteinase inhibitor, precursor thereof and genetic sequences encoding same |
| 09/17/2002 | US6451572 Overexpression of phytase genes in yeast systems |
| 09/17/2002 | US6451570 Mutants of monoamine oxidase B |
| 09/17/2002 | US6451568 First cloning and expression, from a mammalian source, of proteins capable of catalyzing choline- and ethanolaminephosphotransferase reaction site-directed mutagenesis was used to differentiate the residues responsible |
| 09/17/2002 | US6451566 Method for producing dihydroxyacetone-3-phosphate |
| 09/17/2002 | US6451563 Method for making linear, covalently closed DNA constructs |
| 09/17/2002 | US6451562 Polypeptides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) polynucleotides |
| 09/17/2002 | US6451561 Growth hormone variants |
| 09/17/2002 | US6451560 Prokaryotic expression system characterized by alterations to the dlt operon whereby expression of genes encoded therein may be regulated to limit the availability of polypeptides encoded by said genes. |
| 09/17/2002 | US6451559 Expression vector for improved production of polypeptides in yeast |
| 09/17/2002 | US6451557 Method for producing, in yeast, a hydroxylated triple helical protein, and yeast host cells useful in said method |
| 09/17/2002 | US6451556 EF-Tu |
| 09/17/2002 | US6451554 Purified nucleic acid sequence encoding a sodium channel protein wherein said nucleic acid sequence comprises the coding portion of the nucleic acid sequence and producing a mammalian sensory neuron sodium channel protein, wherein the |
| 09/17/2002 | US6451549 Encoded by a polynucleotide; use as reporter molecule |
| 09/17/2002 | US6451546 Plant glurs of the invention may function as signal transducers involved in the regulation of plant growth. the invention also relates to the identification of compounds that modulate the activity of the plant glur and herbicides |
| 09/17/2002 | US6451541 Chaperones capable of binding to prion proteins and distinguishing the isoforms PrPc and PrPsc |
| 09/17/2002 | US6451540 2′-O-alkylthioalkyl and 2′-C-alkythioalkyl containing nucleic acids |
| 09/17/2002 | US6451539 Expression vectors, transfection systems, and method of use thereof |
| 09/17/2002 | US6451538 Antisense modulation of CHK2 expression |
| 09/17/2002 | US6451537 Gene of rice dihydrodipicolinate synthase and DNA relating to the same |
| 09/17/2002 | US6451535 Composition containing DNA coding for a ribozyme and an oligonucleotide substrate, and method for measuring transcription rates |
| 09/17/2002 | US6451534 Kvlqt1 and kcne1 which are genes associated with long qt syndrome. additional sequence data for the two genes are also disclosed. mutations in kvlqt1 which result in long qt syndrome. the intron/exon junction sequence data allow for the |
| 09/17/2002 | US6451531 Dioxetane labeled probes and detection assays employing the same |
| 09/17/2002 | US6451529 Probes for the detection of prostate cancer cells. the probes bind selectively with target polynucleotide sequences selected from the group |
| 09/17/2002 | US6451527 A method of selecting internalizing ligands displayed on a genetic package from a library of ligand displaying genetic packages, comprising: contacting a library of ligand displaying genetic packages with a cell and detection of |
| 09/17/2002 | US6451523 Variant form of the receptor for the obese gene product. the invention relates to methods of detecting this receptor variant in cells and tissues of obese individuals. |
| 09/17/2002 | US6451522 Combining agent to be tested, antibody or antigen-binding fragment which binds to amino terminal domain of mammalian cc-chemokine receptor 2, mammalian cc-chemokine receptor 2 or ligand-binding variant, measuring binding |
| 09/17/2002 | US6451324 Ryegrass pollen allergen |
| 09/17/2002 | US6451323 Recombinant newcastle disease virus RNA expression systems and vaccines |
| 09/17/2002 | US6451322 Retrovirus like particles made non infectious by a plurality of mutations |
| 09/17/2002 | US6451319 Deletion or insertion in dna sequence; vaccines, gene therapy |
| 09/17/2002 | US6451318 Secreted proteins |
| 09/17/2002 | US6451315 Compounds and methods for the diagnosis and treatment of B. microti infection |
| 09/17/2002 | US6451313 Heterotetramer; expression vectors encoding heavy and light chains; viricides |
| 09/17/2002 | US6451311 An antibody which binds procalcitonin but not free calcitonin, free katacalcin and free n-procalcitonin; used as an in vitro or in vivo diagnostic agent |
| 09/17/2002 | US6451310 Preventing t cell activation of b cells by administering antibody cabable of binding protein recognized by monoclonal antibody 5c8 |
| 09/17/2002 | US6451308 Administering mutant polypeptide to treat rheumatoid arthritis and as immunomodulator |
| 09/17/2002 | US6451304 Method for retrovirus vector production by separated gag and pol expression |
| 09/17/2002 | US6451261 Multi-well microfiltration apparatus |
| 09/17/2002 | US6451191 Film based addressable programmable electronic matrix articles and methods of manufacturing and using the same |
| 09/17/2002 | CA2402822A1 Reactive monomers for the oligonucleotide and polynucleotide synthesis, modified oligonucleotides and polynucleotides, and a method for producing the same |
| 09/17/2002 | CA2260007C Method for treating gastrointestinal damage |
| 09/17/2002 | CA2243459C Human antibodies that bind human tnf.alpha. |
| 09/17/2002 | CA2238640C Non-toxic mutants of pathogenic gram-negative bacteria |
| 09/17/2002 | CA2226342C Pap mutants that exhibit anti-viral and/or anti-fungal activity in plants |
| 09/17/2002 | CA2213001C Isolated nucleic acid molecule encoding peptides which form complexes with mhc molecule hla-cw*1601 and uses thereof |
| 09/17/2002 | CA2204151C Cdna encoding a bmp type ii receptor |
| 09/17/2002 | CA2189426C Subtilisin bpn' variants having decreased adsorption and increased hydrolysis |
| 09/17/2002 | CA2187908C Non-splicing variants of gp350/220 |
| 09/17/2002 | CA2172989C Conotoxin peptides |
| 09/17/2002 | CA2158427C Methods and compositions for controlling translation of hcv proteins |
| 09/17/2002 | CA2145405C Nucleotides labelled with an infrared dye and their use in nucleic acid detection |
| 09/17/2002 | CA2131543C Comparative genomic hybridization |
| 09/17/2002 | CA2122036C Bacterial nitroreductase for the reduction of cb 1954 and analogues thereof to a cytotoxic form |
| 09/17/2002 | CA2111853C Substantially pure receptor like tgf-.beta.1 binding molecules and uses thereof |
| 09/17/2002 | CA2095534C Avirulent microbes and uses therefor |
| 09/17/2002 | CA2082933C Method and means to perform biochemical reactions |
| 09/17/2002 | CA2067919C Heterobifunctional antibodies possessing dual catalytic and specific antigen binding properties and methods using them |
| 09/17/2002 | CA2047244C Genetically engineered immunoglobulins |
| 09/16/2002 | CA2376131A1 A method for the production of pharmaceutically active recombinant urokinase |
| 09/16/2002 | CA2373468A1 Reg-like protein |
| 09/15/2002 | CA2373454A1 Recombinant infectious laryngotracheitis virus vaccine |
| 09/15/2002 | CA2339598A1 Dna fragment having promoter function |
| 09/13/2002 | CA2374027A1 Cloning, expression, sequencing, and functional enhancement of monoclonal scfv antibody against venezuelan equine encephalitis virus(vee) |
| 09/12/2002 | WO2002071064A1 Method of examining steroid-responsiveness |
| 09/12/2002 | WO2002071059A1 A system and method for managing gene expression data |
| 09/12/2002 | WO2002071040A2 Use of infrared spectroscopy in genotypic analysis |
| 09/12/2002 | WO2002070755A2 Fen endonucleases |
| 09/12/2002 | WO2002070751A1 Pcr method |
| 09/12/2002 | WO2002070750A2 Method of determining dihydropyrimidine dehydrogenase gene expression |
| 09/12/2002 | WO2002070748A2 Response of dendritic cells to a diverse set of pathogens |
| 09/12/2002 | WO2002070745A2 Polymorphisms in the zf9 gene linked to a predisposition for the development of inappropriate scarring of fibrosis |
| 09/12/2002 | WO2002070744A2 Adenoviral library assay for e2f regulatory genes and methods and compositions for screening compounds |
| 09/12/2002 | WO2002070742A1 Method for the development of gene panels for diagnostic and therapeutic purposes based on the expression and methylatoin status of the genes |
| 09/12/2002 | WO2002070741A2 Methods, systems and computer program products for determining the biological effect and/or activity of drugs, chemical substances and/or pharmaceutical compositions based on their effect on the methylation status of the dna |
| 09/12/2002 | WO2002070740A2 Test system for determining gene toxicities |
| 09/12/2002 | WO2002070739A2 Assay for identifying inhibitors of the rna dependent rna polymerase (ns5b) of hcv |
| 09/12/2002 | WO2002070737A2 Compositions and methods relating to osteoarthritis |
| 09/12/2002 | WO2002070736A2 Method for the detection of nucleic acid molecules |
| 09/12/2002 | WO2002070735A2 Method for the amplification and detection of dna using a transcription based amplification |