Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
11/2003
11/18/2003US6649595 FK506 binding proteins (FKBPs); rapamysin derivatives; multimerizing chimeric proteins in genetically engineered cells using said derivatives
11/18/2003US6649421 Antigen binding protein; use in diagnosis and treatment of cardiac infarction, stroke, arterial occlusion disease and kidney failure due to endothelial dysfunction
11/18/2003US6649411 Also using ADNF III nucleic acid probes to detect the presence of pathologically proliferating cells in human tissues.
11/18/2003US6649409 Method for producing a nucleotide sequence construct with optimized codons for an HIV genetic vaccine based on a primary, early HIV isolate and synthetic envelope BX08 constructs
11/18/2003US6649407 Viral fiber protein for use in the treatment of viral diseases
11/18/2003US6649404 Detecting binding between a immobilized and mobile chemical species (oligonucleotides); signals; use in diagnosis and gene/drug discovery
11/18/2003US6649399 Given nucleotide sequence; use in therapeutic, diagnostic, and pharmacogenomic applications
11/18/2003US6649396 Fiber receptor-independent system for the propagation of adenoviral vectors
11/18/2003US6649393 Mutant form of cytotoxic ribonucleolytic protein which allows production by recombinant methods
11/18/2003US6649392 Mutant form of a cytotoxic ribonucleolytic protein which allows production by recombinant methods
11/18/2003US6649391 Isolated polynucleotide encoding a polypeptide of given sequence; dephosphorylates MAP(mitogen activated protein)-kinase; used for modulating cell proliferation, differentiation and survival
11/18/2003US6649390 Thermophilic alkaline phosphoesterase and its expression
11/18/2003US6649389 Peptide for use in the diagnosis and treatment of cancer, thyroid, diabetes, atherosclerosis, and cardiovascular disorders
11/18/2003US6649388 Polypeptides derived from JNK3
11/18/2003US6649387 Enzymatic oxidative deamination process
11/18/2003US6649382 Methods of making polyhydroxyalkanoate using biosynthesis genes from alcaligenes latus
11/18/2003US6649379 Gene isolated from Corynebacterium glutamicum, Escherichia coli, and Bacillus subtilis, encoding a homoserine dehydrogenase; mutated in carboxy terminus to prevent end-product inhibition; biosynthesis
11/18/2003US6649378 Self-contained device integrating nucleic acid extraction, amplification and detection
11/18/2003US6649375 Adenoviral vectors for enhanced gene expression
11/18/2003US6649374 Recombinant Chlamydia trachomatis PGP3 antigen
11/18/2003US6649373 Use of trans-activation and CIS-activation to modulate the persistence of expression of a transgene
11/18/2003US6649372 Which expresses heterologous nucleotide sequences; introducing expression vectors, nucleotprotein, and polymerase into a cell; allowing complex to form; culturing; use in vaccines
11/18/2003US6649370 Isolated polynucleotide which induces a immune response when administered to a mammal; expression vectors; vaccines
11/18/2003US6649355 Lipoxygenase proteins and nucleic acids
11/18/2003US6649353 Method for influencing the p53 linkage to target genes
11/18/2003US6649350 Electrochemical sensor using intercalative, redox-active moieties
11/18/2003US6649347 Use of methylated nucleic acid segments for isolating centromere DNA
11/18/2003US6649345 Phenylalanine hydroxylase gene variants, and amino acid and pterin homeostasis, in the definition, detection, treatment and prevention of psychotic, mood and personality disorders
11/18/2003US6649340 Protein which contains a predetermined amino acid in the hypervariable region of the antigen-binding site; use in studying structure/ function and in developing new enzymes and antibodies
11/18/2003US6649339 Screening for the presence of a parvovirus genome equivalent using nucleic acid amplification; purification
11/18/2003US6649171 Diagnostic, prophylactic and therapeutic uses, i.e. vaccines; antibiotic resistant bacteria responsible for much of the otitis media in young children
11/18/2003US6649169 Cold-adapted equine influenza viruses
11/18/2003US6649164 (RANK); RANK is a member of the TNF superfamily; used to regulate an immune response
11/18/2003US6649159 Monitoring preferential gene expression of a gene; transfering nucleotide sequences to cells, incubate, monitor intensity of fluoresence
11/18/2003US6649158 Methods and compositions to induce antitumor response
11/18/2003CA2265508C Bone morphogenetic protein-16 (bmp-16) compositions
11/18/2003CA2223433C Ob protein compositions and methods
11/18/2003CA2143845C Self-assembling recombinant papillomavirus capsid proteins
11/18/2003CA2045208C Inhibition of coloration of human serum albumin
11/18/2003CA2014518C Lipopolyamines, their preparation and their use
11/18/2003CA1341447C Mutant t-pa with kringle replacement
11/18/2003CA1341446C Tissue plasminogen activator analogs having modified growth factor domains
11/17/2003CA2387006A1 A novel mouse with deficiency of gene of neutrophil chemotactic factor lect2
11/15/2003CA2382767A1 Plant fad2 coding sequence balancing for fatty acid profiling in edible oils
11/13/2003WO2003094088A1 Mouse olfactory receptor gene superfamily specification
11/13/2003WO2003093817A2 Method of identifying ligands for nuclear receptors
11/13/2003WO2003093797A2 Polynucleotides for the detection and quantification of hepatitis b virus nucleic acids
11/13/2003WO2003093794A2 Methods for discovering tumor biomarkers and diagnosing tumors
11/13/2003WO2003093789A2 Method for measuring ion channel activity
11/13/2003WO2003093512A1 Methods and compositions for the modification of nucleic acids
11/13/2003WO2003093508A1 Method of detecting rheumatoid arthritis by detecting overexpression of wnt
11/13/2003WO2003093506A2 Mitochondrial polymorphisms linked to a predisposition for the development of inappropriate scarring or fibrosis
11/13/2003WO2003093505A2 Method for determining the presence of an unconventional transmissible agent responsible for transmissible subacute spongiform encephalopathy
11/13/2003WO2003093501A2 Ssh based methods for identifying and isolating unique nucleic acid sequences
11/13/2003WO2003093492A2 Compositions and methods for determining susceptibility of hepatitis c virus to anti-viral drugs
11/13/2003WO2003093486A1 In situ generation of viral vectors
11/13/2003WO2003093485A2 Optimization of transgene expression in mammalian cells
11/13/2003WO2003093484A1 Insect resistant plants and methods for making the same
11/13/2003WO2003093483A1 Wound-inducible expression in plants
11/13/2003WO2003093482A2 Method for producing multiple unsaturated fatty acids in plants
11/13/2003WO2003093481A1 Nucleic acid for autonomous replication in micro-organisms of the acetobacteraceae family
11/13/2003WO2003093479A1 Improved raav expression systems and methods for enhancing transduction of mammalian neural cells
11/13/2003WO2003093478A1 Immunoconjugates for the treatment of tumours
11/13/2003WO2003093477A1 Novel carbonyl reductase, gene thereof and use of the same
11/13/2003WO2003093476A1 Vector with modified protease-dependent tropism
11/13/2003WO2003093475A1 Compositions and methods for the modification of gene expression_using the superubiquitin promoter from pinus radiata
11/13/2003WO2003093474A1 Psp94 binding protein and psp94 diagnostic assays
11/13/2003WO2003093473A1 A multimeric self-cleaving ribozyme construct
11/13/2003WO2003093472A2 Cgrp binding nucleic acids
11/13/2003WO2003093471A1 Novel 88 phage vectors
11/13/2003WO2003093469A2 Methods for delivering nucleic acid molecules into cells and assessment thereof
11/13/2003WO2003093468A2 Expression system for large functional proteins
11/13/2003WO2003093467A1 Proteins having an (r)-hydroxynitrile lyase activity and extracted from prunus laurocerasus and sorbus aucuparia
11/13/2003WO2003093466A1 Human rhomboid-related protein
11/13/2003WO2003093465A1 FACTOR VII OR VIIa POLYPEPTIDE VARIANTS
11/13/2003WO2003093464A1 Compositions isolated from forage grasses and methods for their use
11/13/2003WO2003093460A1 Method for direct rescue and amplification of integrated viruses from cellular dna of tissues
11/13/2003WO2003093459A1 Stable cytochrome p450 24 (cyp24) expressing cell line and methods and uses thereof
11/13/2003WO2003093455A2 Adenovirus vectors for immunotherapy
11/13/2003WO2003093453A2 Bacillus licheniformis mutant host cell
11/13/2003WO2003093451A2 Transposable elements in rice and methods of use
11/13/2003WO2003093450A2 Maize clavata3-like polynucleotide sequences and methods of use
11/13/2003WO2003093449A2 Methods for delivery of nucleic acids
11/13/2003WO2003093443A2 Alcam and alcam modulators
11/13/2003WO2003093441A2 A method of regulating gene expression
11/13/2003WO2003093440A2 Methods and compositions for expressing a nucleic acid in a dendritic cell
11/13/2003WO2003093437A2 Production of papillomavirus vaccines in plants
11/13/2003WO2003093436A2 Treatment for phenylketonuria
11/13/2003WO2003093432A2 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
11/13/2003WO2003093431A2 Ablated slam-dependent entry
11/13/2003WO2003093430A2 Methods and compositions for use in preparing sirnas
11/13/2003WO2003093428A2 Gene targeting using replicating dna molecules
11/13/2003WO2003093426A2 In vitro mutagenesis, phenotyping, and gene mapping
11/13/2003WO2003093424A2 In vivo ssdna expression vectors for altering gene expression
11/13/2003WO2003093422A2 Novel tissue factor targeted antibodies as anticoagulants
11/13/2003WO2003093421A2 Methods and compositions for use in homologous recombination
11/13/2003WO2003093417A2 Lentiviral vector particles resistant to complement inactivation
11/13/2003WO2003093414A2 Transgenic animal model for spliceosome-mediated rna trans-splicing
11/13/2003WO2003093411A2 Ice1, a regulator of cold induced transcriptome and freezing tolerance in plants
11/13/2003WO2003093409A2 Promoters exhibiting endothelial cell specificity and methods of using same