Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
11/2003
11/26/2003CN1128878C Coding sequence of human methionine sulfoxide rductase, its encoded polypeptide and its preparing method
11/26/2003CN1128877C High lysine protein gene and method for increasing content of lysine and protein in seeds of gramineous crops
11/26/2003CN1128876C Transferrin receptor genes of moraxella
11/26/2003CN1128875C Method for preparing polypeptide variants
11/26/2003CN1128873C Recombinant yeasts for effective fermentation of glucose and xylose
11/25/2003USRE38331 Cells with altered betaine catabolism and their use in producing metabolites or enzymes
11/25/2003US6653535 Methods for modulating water-use efficiency or productivity in a plant by transforming with a DNA encoding a NAPD-malic enzyme operably linked to a guard cell or an epidermal cell promoter
11/25/2003US6653533 Vectors comprising foreign nucleotide sequence; transcription factors that enhance activation of defense mechanisms
11/25/2003US6653532 Methods for influencing the flowering behavior of plants by enhancing the saccharose-cleaving activity in the apical meristem
11/25/2003US6653531 Chorismate synthase from plants
11/25/2003US6653530 Transformation with a vector comprising transcriptional initiation region, nucleotide sequence encoding a plastid transit peptide and phytoene synthase; neutraceuticals; high oleic acid; longer shelf life and stability
11/25/2003US6653529 Transforming monocotyledon cells with nucleic acid constructs linked to promoters, then culturing in imazethapyr, imazameth, imazapyr, imazamox or imazaquin, to form hydrids having herbicide resistance
11/25/2003US6653528 Isolated polynucleotide of given sequence; vectors; decreased concentration useful in paper industry and digestibility of forage crops; increase causes high mechanical strength of wood and rot resistance
11/25/2003US6653527 Isolated nucleic acid encoding the N-terminal amino acids of a COP1 protein; transforming cells; Arabidopsis, spinach, tomatoes, rice
11/25/2003US6653526 Transgenic mice exhibiting increased susceptibility to seizures
11/25/2003US6653473 Fluorescent quenching detection reagents and methods
11/25/2003US6653467 Antisense oligonucleotide selected from RNA or DNA, of given sequence, where each uracil is replaced with thymine; used to correct the shift of the reading frame; dystrophin
11/25/2003US6653466 Active principle comprises antisense oligonucleotide consisting of a 20 to 50-nucleotide sequence against exon 19 of dystrophin pre-mRNA
11/25/2003US6653463 Biocidal protein
11/25/2003US6653460 Voltage-gated calcium channel antagonist and method
11/25/2003US6653459 Isolated nucleic acid encoding a polypeptide of given sequence; use in producing glycoproteins with minimal and uniform sugar residues; low antigenicity; side-effect reduction of drugs
11/25/2003US6653458 Modified oligonucleotides
11/25/2003US6653452 Nucleotide sequences coding enzymatic polypeptide for use in the treatment of parasitic infections, tumors, leukemias, Alzheimer's disease, autoimmune disorders and viral diseases
11/25/2003US6653450 Mutated recombinant collagens
11/25/2003US6653449 Isolated from jellyfish; use in development of drugs for treatment of sting injuries and in pharmaceuticals where platelet agglutination is desired
11/25/2003US6653448 Wnt-7B-like polypeptides and nucleic acids encoding same
11/25/2003US6653447 ULBP DNA and polypeptides
11/25/2003US6653446 Nucleotide sequences which code enzymatic polypeptide for use in treatment of gout, kidney, blood and preferential genetic disorders
11/25/2003US6653445 Chemotactic cytokine V (CCV); isolated protein of given sequence; use in diagnostics and as anti-viral or anti-tumor agent
11/25/2003US6653444 Polypeptides comprising a B7 extracellular domain
11/25/2003US6653382 Ethylene-unsaturated carboxylic acid copolymer; ionomers; resilience, melt processability
11/25/2003US6653326 Hydroxylamine derivatives useful for enhancing the molecular chaperon production and the preparation thereof
11/25/2003US6653292 Stimulating Th1 pattern of immune activation, cytokine production, NK lytic activity and B cell proliferation; modulating with nucleic acid sequences containing unmethylated CpG dinucleotides
11/25/2003US6653285 Polypeptide inhibitors and enhancers of glycosaminoglycans such as hyaluronic acid, chondroitin sulfate, dermatan sulfate, heparin, keratan sulfate, chitin and chitosans; antiinflammatory and anticarcinogenic agents; infections
11/25/2003US6653284 Keratinocyte growth factor-2 formulations
11/25/2003US6653280 Antifungal polypeptide AlyAFP from Alyssum and methods for controlling plant pathogenic fungi
11/25/2003US6653134 Obtaining a bone marrow sample from a human, isolating stromal cells, and administering to the central nervous system of the patient; treating a genetic disease, a tumor, trauma and stroke
11/25/2003US6653133 Antisense modulation of Fas mediated signaling
11/25/2003US6653132 IRES sequences with high translational efficiency and expression vectors containing the sequence
11/25/2003US6653125 Synthetic hepatitis C genes
11/25/2003US6653118 Deoxyribonuclease, gene encoding same and use thereof
11/25/2003US6653116 Peptide for use in the treatment of inflammation, cancer, arteriosclerosis and psoriasis
11/25/2003US6653115 D-sorbitol dehydrogenase gene
11/25/2003US6653113 Modifying DNA sequence in genome by homologous recombination using isogenic constructs; can contain markers for antibiotic resistance and ability to grow on selected substrate
11/25/2003US6653111 Containing a recombinant plasmid pVIC40 and deposited on Nov. 19, 1987 in the collection of microorganism cultures at the USSR Antibiotics Rearch Institute under Reg. No. 1867; efficiency; nutrients; feeds; drugs
11/25/2003US6653110 Generation of glutamic acid by fermentation; obtain microorganism, incubate in nutrient broths, recover glutamic acid
11/25/2003US6653108 Process for selective amplification of a full-length cDNA involving an anchor nucleic acid
11/25/2003US6653106 Topoisomerase-based ligation and cloning methods
11/25/2003US6653103 For inhibiting export of nucleic acids from nucleus to cytoplasm of a cell
11/25/2003US6653101 Transforming a eukaryotic host by transfection with transcription units containing genes encoding a transactivator; promoters; use for increasing amount of protein expressed
11/25/2003US6653100 hKCa3/KCNN3 small conductance calcium activated potassium channel: A diagnostic marker and therapeutic target
11/25/2003US6653099 Plant UDP-glucose dehydrogenase
11/25/2003US6653094 Diagnosing pancreatic defect in humans; obtain organelle sample, detect preferential organelle, monitor sample for organelle defect, diagnose pancreatic defect
11/25/2003US6653081 Methods for monitoring antiretroviral therapy and guiding therapeutic decision in the treatment of HIV/AIDS
11/25/2003US6653080 Loop probe hybridization assay for polynucleotide analysis
11/25/2003US6653072 Improving expression of a protein encoded by DNA substrate by assembling oligonucleotides into recombinant nucleic acids and using it to transform cells; recursive sequence recombination
11/25/2003US6653069 Method for quality control of an attenuated vericella live vaccine
11/25/2003US6653068 Generation of specific binding partners binding to (poly)peptides encoded by genomic DNA fragments or ESTs
11/25/2003US6652878 Cell transfection apparatus and methods for making and using the cell transfection apparatus
11/25/2003US6652860 Peptide, apoEp 1.B, compositions and uses thereof
11/25/2003US6652859 Diagnosis and therapy
11/25/2003US6652858 Administering an OX-2 protein or a nucleic acid encoding it to preventing graft rejection, fetal loss, autoimmune disease, and allergies; immunosuppressants; gene therapy
11/25/2003US6652854 Administering agents that hinder CD30/CD30L (CD30L=ligand of CD30) binding; animal model of arthritis for drug screening
11/25/2003US6652851 Cloning and recombinant production of polistinae venom enzymes, such as phospholipase and hyaluronidase, and immunological therapies based thereon
11/25/2003US6652850 Adeno-associated viral liposomes and their use in transfecting dendritic cells to stimulate specific immunity
11/25/2003US6652848 Dendritic cell hybrids
11/25/2003US6652808 Electric field assisted self-assembly of functionalized programmable nucleic acids, modified structures and other selective affinity or binding moieties
11/25/2003US6652575 Stent with smooth ends
11/25/2003CA2194166C Multi-stage cascase boosting vaccine
11/25/2003CA2100860C A receptor tyrosine kinase target protein cdna cloning method and hgrb proteins
11/25/2003CA2086888C Whooping cough vaccine
11/25/2003CA2083837C Recombinant dna coding for a novel protein having .beta.-1,3 glucanase activity, bacteria containing this dna, transformed plant cells and plants
11/25/2003CA2053230C Potato .alpha. -amylase genes
11/21/2003CA2428112A1 Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasia
11/21/2003CA2424937A1 Methods for improving efficiencies in livestock production
11/21/2003CA2387003A1 Method for improving efficiencies in livestock production
11/20/2003WO2003096017A1 Methods and compositions for inducing an immune response
11/20/2003WO2003096015A1 Biomolecular substrate, method of testing or diagnosis with use thereof and apparatus therefor
11/20/2003WO2003095973A2 Nanoparticle probes with raman spectroscopic fingerprints for analyte detection
11/20/2003WO2003095971A2 Posh nucleic acids, polypeptides and related methods
11/20/2003WO2003095680A1 Methods for the enrichment of low-abundance polynucleotides
11/20/2003WO2003095678A1 Ldl receptor-related proteins 1 and 2 and treatment of bone or cartilage conditions
11/20/2003WO2003095677A1 Nucleic acid probes for detection of non-viral organisms
11/20/2003WO2003095674A2 Methods for evaluating a disease condition by detection of particle and non-particle bound nucleic acids in blood plasma and serum
11/20/2003WO2003095671A1 Method of diagnosis and treatment for affective disorders
11/20/2003WO2003095670A2 Process for generating sequence-specific proteases by directed evolution and use thereof
11/20/2003WO2003095667A2 Autoimmune conditions and nadph oxidase defects
11/20/2003WO2003095664A2 Pyrophosphorolysis activated polymerization (pap)
11/20/2003WO2003095663A2 Modified t lymphocytes and uses therefor
11/20/2003WO2003095658A1 Homologous recombination into bacterium for the generation of polynucleotide libraries
11/20/2003WO2003095656A1 Recombinant fowlpox virus
11/20/2003WO2003095655A2 Methods for increasing oil content in plants
11/20/2003WO2003095654A2 Method for producing a transgenic plant having modified transport of substances
11/20/2003WO2003095653A1 Promoters having a modified transcription efficiency and derived from methyltrophic yeast
11/20/2003WO2003095652A2 Expression constructs for producing double-stranded (ds) rna and the use thereof
11/20/2003WO2003095651A1 Process for producing mevalonic acid
11/20/2003WO2003095650A1 Human prolyl 4-hydroxylase
11/20/2003WO2003095649A1 Nobel glyphosate-tolerant 5-enolpyruvylshikimate-3-phospha synthase and gene encoding it
11/20/2003WO2003095647A2 CHIMERIC snRNA MOLECULES CARRYING ANTISENSE SEQUENCES AGAINST THE SPLICE JUNCTIONS OF THE DYSTROPHIN GENE AND THEIR THERAPEUTIC APPLICATIONS
11/20/2003WO2003095646A1 Isolating nucleic acid