Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
12/2003
12/16/2003US6664379 Nuclease inhibitor cocktail
12/16/2003US6664376 Chimeric polypeptide molecules
12/16/2003US6664375 Nucleotide sequences coding binding protein for use in the treatment of alzheimer's disease and nervous system disorders
12/16/2003US6664373 TWIK-5 potassium channel polypeptides and uses therefor
12/16/2003US6664370 Immune reactivity to HER-2/neu protein for diagnosis and treatment of malignancies in which the HER-2/neu oncogene is associated
12/16/2003US6664232 HLA-A2 restraint tumor antigen peptide originating in SART-1
12/16/2003US6664231 Based on Domain III (amino acids 142-169) of bactericidal/ permeability-increasing protein; candida, aspergillus, cryptococcus
12/16/2003US6664227 Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains
12/16/2003US6664112 Methods for improving the sequence fidelity of synthetic double-stranded oligonucleotides
12/16/2003US6664109 Genetically engineered soybean cell for use as expression tool in plant genetic engineering
12/16/2003US6664108 Mobilization of viral genomes from T-DNA using site-specific recombination systems
12/16/2003US6664107 Insertion of exogenous DNA into genome of mammals producing transgenic mammals with decreased/suppressed endogenous gene expression and/or with expression of a novel gene(s); use in screening drugs for immunostimulatory effects
12/16/2003US6664105 Polynucleotide encoding a polypeptide having heparanase activity and expression of same in genetically modified cells
12/16/2003US6664103 Chemically assembled nano-scale circuit elements
12/16/2003US6664098 Cellular differentiation and proliferation; ligands, membrane receptors; antigrowth agents; use of human Notch ligand, human Delta molecule, in development of drug candidates for differential regulation of undifferentiated cells
12/16/2003US6664094 Use of mutants of Neisseria gonorrhoeae in vaccine production which contain mutations in a major outer membrane protein gene such that no immunologically functional polypeptides encoded by said gene are produced
12/16/2003US6664092 Nucleic acid sequences; amino acid sequences; vectors; host cells; genetic engineering; Aspergillus oryzae; use in the production of protein hydrolysates having desirable organoleptic properties and high degrees of hydrolysis
12/16/2003US6664090 Carboxylesterase nucleic acid molecules, proteins and uses thereof
12/16/2003US6664089 Nucleotide sequences coding enzymatic proteins; for use in the treatment of cell proliferation and differention disorders; antiproliferative agents
12/16/2003US6664088 Production of vanillin
12/16/2003US6664087 Isolated human kinase proteins
12/16/2003US6664084 Isolated nucleic acid molecules encoding human glucuronyltransferase proteins, and related products and processes
12/16/2003US6664082 Microorganism belonging to the genus Gluconobacter, which has an engineered gene for the biological activity of reducing L-sorbose which is more than 90% non- functional in developing the said biological activity.
12/16/2003US6664080 TaqMan™-PCR for the detection of pathogenic E. coli strains
12/16/2003US6664079 Sequencing nucleic acid; obtain nucleotide sequences, incubate in reaction mixture, apply to solid support, determine nucleotide sequences
12/16/2003US6664078 Culturing a bacterial transformant in an antibiotic-free batch medium and feeding the portion of a feed-back medium after the rise of the concentration of dissolved oxigen above a threshold-set point; isolation of ccc plasmid DNA
12/16/2003US6664077 DNA encoding ACPL
12/16/2003US6664076 Modification of bacteria
12/16/2003US6664075 Polypeptide binds to patched protein; genetic engineering
12/16/2003US6664072 Kits for screening for modulators of the motor protein HsKip3b
12/16/2003US6664068 Antibodies, antiapoptotic agents
12/16/2003US6664066 Modified Morbillivirus V proteins
12/16/2003US6664064 Number of repeat sequences which are present in a sample is determined by means of melting temperature analysis of the hybridization product of the target nucleic acid with a hybridization probe
12/16/2003US6664063 Methods for separating,fractionating and analyzing gene of virus existing in hydrosphere
12/16/2003US6664060 Arrays with mask layers and methods of manufacturing same
12/16/2003US6664058 A nucleotide, e.g., 6-(beta-D-2-Deoxyribofuranosyl)-5-hydro-methyl-8H-pyrimido(4,5 -c)(1,2)pyridazin-7-one-5'-triphosphate, incorporated into a polynuceotide or an oligomucleotide; viricides; labels
12/16/2003US6664057 Hybridization of probe; diagnosis of breast cancer
12/16/2003US6664055 Diagnosing mood/psychological disorders in humans; obtain sample, monitor allelic genotype or phenotype, monitor pattern of kainate receptor protein, compare to control, evaluate for mood/psychological disorder
12/16/2003US6664054 Enhancing the expression of down-regulated polynucleotides or introducing down-regulated polypeptide or protein to cell can decrease the growth and/or abnormal characteristics of cancer and dysplasia
12/16/2003US6664051 Fixation of nucleotide derivatives to solid carrier
12/16/2003US6664048 Combination of selection steps used to detect clones that express interacting molecules from false positive clones.
12/16/2003US6664046 mRNA splice variants can be discriminated from the predominant splice variants which encode inactive forms based on the presence of the beta region, the 182 nucleotide deletion encompassing exon 7 and exon 8. present invention
12/16/2003US6664040 Complexing to polypeptides; antiproliferation agent
12/16/2003US6663906 Expression of fructose 1,6 bisphosphate aldolase in transgenic plants
12/16/2003US6663872 Immune response
12/16/2003US6663871 Non-replicating or replication- impaired pox virus vector carrying at least one CD8 T cell epitope which is also present in the priming composition, malaria
12/16/2003US6663870 Methods for promoting growth of bone using zvegf3
12/16/2003US6663868 Heat shock protein-based vaccines and immunotherapies
12/16/2003US6663867 Administering to a patient a hybrid protein comprising two different coexpressed amino acid sequences forming heterodimer, each comprising an amino acid sequence of tumor nacrosis factor binding protein and a subunit of hCG, FSG, LH
12/16/2003US6663858 Antitumor, gene therapy
12/16/2003US6663857 In vivo gene transfer using implanted retroviral producer cells
12/16/2003US6663856 Gene therapy
12/16/2003CA2286879C Novel method for the production of anti-human antigen receptors and uses thereof
12/16/2003CA2214359C Dna diagnostics based on mass spectrometry
12/16/2003CA2202167C Molecular tagging system
12/16/2003CA2134751C Monoclonal antibodies and their use
12/16/2003CA2096604C Protein c derivatives
12/16/2003CA2072627C Recombinant herpes simplex viruses vaccines and methods
12/16/2003CA2068614C Esterase genes, esterase, recombinant plasmids and transformants containing the recombinant plasmid and methods of producing optically active carboxylic acids and their enantiomeric esters using said transformants
12/14/2003CA2432496A1 Diagnostic and therapeutic uses of sufu gene
12/14/2003CA2430259A1 Vaccine
12/11/2003WO2003102590A1 Methods of detecting target molecules and molecular in teractions
12/11/2003WO2003102588A2 Diagnostic agent, method for detecting a carcinoma, and means for the treatment thereof
12/11/2003WO2003102584A2 Semaphorin-like proteins and methods of using same
12/11/2003WO2003102582A1 Method for detecting biochemical reagin biochip
12/11/2003WO2003102578A2 High throughput cellular response assay using microarrays
12/11/2003WO2003102245A1 Antisense modulation of beta-site app-cleaving enzyme 2 expression
12/11/2003WO2003102244A1 Antisense modulation of beta-site app-cleaving enzyme expression
12/11/2003WO2003102242A1 Notch 1 inhibitors for inducing apopotosis
12/11/2003WO2003102239A2 Met/fret based method of target nucleic acid detection whereby the donor/acceptor moieties are on complementary strands
12/11/2003WO2003102238A2 Direct pcr quantification
12/11/2003WO2003102237A1 Treatment with cytokines
12/11/2003WO2003102234A1 Method for high-throughput integrated chemical and biochemical reactions
12/11/2003WO2003102232A2 Amplification of ribonucleic acids
12/11/2003WO2003102231A1 Method for parallelly sequencing a nucleic acid mixture by using a continuous flow system
12/11/2003WO2003102230A1 Pthrp-based prediction and diagnosis of bone disease
12/11/2003WO2003102221A1 Screening method for regulatory enzymes employing tribrid (tri-hybrid) system
12/11/2003WO2003102219A2 Improved pseudotyped retroviruses
12/11/2003WO2003102215A2 Methods of identifying and isolating stem cells and cancer stem cells
12/11/2003WO2003102214A2 Method for efficient rna interference in mammalian cells
12/11/2003WO2003102213A2 Error-prone dna polymerase i mutants and methods for targeted random mutagenesis in continuous culture using error-prone dna polymerase i mutants
12/11/2003WO2003102206A2 Sgk and nedd used as diagnostic and therapeutic targets
12/11/2003WO2003102203A1 Stabilized biocatalysts and methods of bioconversion using the same
12/11/2003WO2003102201A2 Methods and materials for the production of d-lactic acid in yeast
12/11/2003WO2003102200A2 Fermentation process using specific oxygen uptake rates as a process control
12/11/2003WO2003102199A1 New gdf-9 and gdf-9b (bmp-15) sequences for altering mammalian ovarian function and ovulation rate
12/11/2003WO2003102198A1 Method for the stable expression of nucleic acids in transgenic plants, controlled by a parsley-ubiquitin promoter
12/11/2003WO2003102197A1 Transgenic plants with controlled distribution of a trait to progeny
12/11/2003WO2003102196A1 Vectors for expression of biotinylated proteins in mammalian cells, and their use for identification of protein-nucleic acid interactions in vivo
12/11/2003WO2003102195A1 Protein hydrolysate rich in tripeptides
12/11/2003WO2003102194A1 Chondroitin synthetase and dna coding for the enzyme
12/11/2003WO2003102193A1 Chondroitin synthetase and nucleic acid coding for the enzyme
12/11/2003WO2003102192A1 Methods of purification of cytochrome p450 proteins and of their crystallizing
12/11/2003WO2003102191A1 Immunogenic sequences
12/11/2003WO2003102190A2 Bacterial polypeptides involved in viability
12/11/2003WO2003102189A1 Allergen from mugwort pollen
12/11/2003WO2003102188A1 Mutated androgen receptor, cancer cells expressing the same, method of constructing the same and use thereof
12/11/2003WO2003102187A1 Self-coalescing or self-aggregating proteins derived from a membrane translocating sequence
12/11/2003WO2003102186A1 Dna inducing cancer cell-specific expression and cancer cell-specific expression vector
12/11/2003WO2003102185A2 Methods and compositions for treating neoplasia relating to hnrnp a1 and a2 nucleic acid molecules