Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
12/2003
12/18/2003US20030232375 Has symptoms such as obesity, diabetes, hypogonadism, mental retardation, renal cancer and other renal abnormalities, retinopathy and polydactyly or limb deformities; used in diagnosis and therapy of BBS and in drug screening
12/18/2003US20030232366 Polyvalent cation-sensing receptor in Atlantic Salmon
12/18/2003US20030232360 An in vitro system that recapitulates regulated mRNA stability and turnover of exogenous RNA substrates; used to identify agents capable of modulating RNA turnover in the presence of RNA stability modifying agents
12/18/2003US20030232358 Identifying the genetic factors responsible for cell differentiation based on expression cloning
12/18/2003US20030232357 A heat-stable enzyme having a DNA helicase activity, and a structure-specific endonuclease activity; obtained by cloning a gene encoding the enzyme from chromosomal DNA of a a sulfur-metabolizing thermophilic archaebacteria
12/18/2003US20030232355 A compound containing a first and a second polymeric strands, and each strand includes a sequence of ligands covalently bound by linkeres, atleast one linker selected from an amide, thioamide, sulfinamide or sufonamide
12/18/2003US20030232354 Use of electron transfer moieties with different redox potentials to electronically detect nucleic acids, such as sequencing of DNA
12/18/2003US20030232349 Nucleic acid and amino acid sequences of proteases and the use of these sequences in the diagnosis and treatment of gastrointestinal, cardiovascular, autoimmune/inflammatory, cell proliferative, and neurological disorders
12/18/2003US20030232347 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
12/18/2003US20030232346 Measuring the distance between labeled nucleotides, such as nucleotides labeled with bulky groups
12/18/2003US20030232342 Simple, efficient, and accelerated method for enzyme-catalyzed in vitro modification and synthesis of nucleic acid using microwave irradiation
12/18/2003US20030232338 Polynucleotides encoding polypeptides involved in one-carbon compound metabolism in methylophilus methylotrophus
12/18/2003US20030232335 Minicell-based screening for compounds and proteins that modulate the activity of signalling proteins
12/18/2003US20030232334 Novel compositions and methods for cancer
12/18/2003US20030232333 Cleaving single-stranded nucleic acid sequences at a desired location, using a restriction endonuclease that is active at the chosen temperature
12/18/2003US20030232332 Novel proteins and nucleic acids encoding same
12/18/2003US20030232331 Novel proteins and nucleic acids encoding same
12/18/2003US20030232330 Detection and identification of enteric bacteria
12/18/2003US20030232329 A specific nucleic acid sequence that encodes a portion of a new human CRH receptor-related G protein-coupled receptor
12/18/2003US20030232326 Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences
12/18/2003US20030232325 Contacting a host cell protein or a peptide containing a WW domain with a viral protein or peptide with an amino acid sequence corresponding to the site that binds to WW doamin, to permit binding and forming complex in presence of sample
12/18/2003US20030232324 Chimeric alphavirus replicon particles
12/18/2003US20030232323 Identifying an agents which inhibit the interaction between a PD-1 ligand and a PD-1 polypeptide, from test agents, determining whether interaction is inhibited, and such agent unable to inhibit interaction, modulates immune response
12/18/2003US20030232074 For stimulating immune activation; for screening immunostimulatory compounds
12/18/2003US20030232061 For therapy of respiratory tract infection in a mammal
12/18/2003US20030232060 Administering an immunizing composition comprising: a carrier; a plasmid encoding an attenuated, doxycycline-inducible proviral molecular clone of the human immunodeficiency virus type 1 (HIV-1), to induce viral expression of the plasmid
12/18/2003US20030232058 Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
12/18/2003US20030232049 Multispecific reagent for selectively stimulating cell surface receptors
12/18/2003US20030232047 Platlet glycoprotein IB alpha fusion polypeptides and methods of use thereof
12/18/2003US20030232041 For use in food and feeds
12/18/2003US20030232037 Immunology, gene therapy
12/18/2003US20030232036 Alphavirus RNA replicon systems
12/18/2003US20030232035 Capable of expressing a heterologous sequence in target cells; vaccines
12/18/2003US20030232034 Antisense modulation of junctional adhesion molecule 3 expression
12/18/2003US20030232022 P. gingivalis antigenic composition
12/18/2003US20030232009 Used to block undesirable immune reactions in patients with transplant rejection and autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and autoimmune diabetes
12/18/2003CA2855445A1 Methods and compositions for production of maize lines with increased transformability
12/18/2003CA2493890A1 Methods for using adamts-12, an integrin and metalloprotease with thrombospondin motifs
12/18/2003CA2489153A1 Modified byrodin 1 with reduced immunogenicity
12/18/2003CA2489083A1 Method for identifying agonists or antagonists for the g-protein coupled mas-like 1 receptor
12/18/2003CA2489054A1 Chromoprotein
12/18/2003CA2489053A1 Chromoprotein
12/18/2003CA2488932A1 Transgenic mammals expressing polyglutamine
12/18/2003CA2488883A1 Method for identifying agonists or antagonists for the gpr45-like/gpr63 receptor
12/18/2003CA2488778A1 Assay to detect replication competent viruses
12/18/2003CA2488769A1 Composition and methods for obtaining nucleic acids from sputum
12/18/2003CA2488682A1 Gene differentially expressed in breast and bladder cancer and encoded polypeptides
12/18/2003CA2488668A1 Modifying the dna recombination potential in eukaryotes
12/18/2003CA2488633A1 Device for multiple simultaneous gene transfer
12/18/2003CA2488621A1 Genes and polypeptides relating to hepatocellular or colorectal carcinoma
12/18/2003CA2488575A1 Three dimensional vaginal tissue model containing immune cells
12/18/2003CA2488558A1 Prevention and reduction of blood loss
12/18/2003CA2488497A1 Neuroprotective synergy of erythropoietin and insulin-like growth factor
12/18/2003CA2488449A1 Screening methods
12/18/2003CA2488382A1 Methods and compositions for detecting cancers
12/18/2003CA2488332A1 Methods and compositions for production of maize lines with increased transformability
12/18/2003CA2488330A1 Improvements for combinatorial oligonucleotide pcr
12/18/2003CA2488328A1 Retrons for gene targeting
12/18/2003CA2488249A1 Spliceosome mediated rna trans-splicing in stem cells
12/18/2003CA2488246A1 Spliceosome mediated rna trans-splicing and correction of factor viii genetic defects using spliceosome mediated rna trans spling
12/18/2003CA2488059A1 Non-polymeric hematopoietic cell clots for delivery of active agents
12/18/2003CA2487943A1 Methods of diagnosing & treating diabetes and insulin resistance
12/18/2003CA2487924A1 Use of corticotroph-derived glycoprotein hormone to treat inflammation and potentiate glucocorticoid action
12/18/2003CA2487907A1 Immunogenic compositions comprising a xenogenic prostate protein p501s
12/18/2003CA2487831A1 Immunogenic compositions
12/18/2003CA2487438A1 Methods of treating and diagnosing diabetes with cx3cr1 modulators
12/18/2003CA2487077A1 Isolated nucleic acid molecule encoding a novel centromere-associated motor protein, and uses thereof
12/18/2003CA2486362A1 Novel recombinant anticoagulant proteins
12/18/2003CA2486270A1 Vegfr modulating agents and methods for liver growth and liver protection
12/18/2003CA2486118A1 Flexible vaccine assembly and vaccine delivery platform
12/18/2003CA2485874A1 T cell receptor cdr3 sequences and methods for detection
12/18/2003CA2480351A1 Improvements in and relating to a method of dna testing for mycobacterium paratuberculosis strains
12/18/2003CA2473321A1 Flavivirus vaccines
12/17/2003EP1371988A2 Assay for the determination of the hormonal effect of compounds
12/17/2003EP1371983A1 Immunoassay, reagent for immunoassay, and production method of the same
12/17/2003EP1371732A1 Fused protein having beta 1,2-n-acetylglucosaminyltransferase ii activity and process for producing the same
12/17/2003EP1371731A1 Aminoketone asymmetric reductase and nucleic acid thereof
12/17/2003EP1371730A2 Recombinant poxvirus for chimeric proteins of the human immunodeficiency virus
12/17/2003EP1371729A2 Use of ttf3 ligands for the diagnosis and therapy of cancer
12/17/2003EP1371728A1 Gene encoding adseverin
12/17/2003EP1371727A1 Recombinant gene containing inverted repeat sequence and utilization thereof
12/17/2003EP1371725A1 Novel aminopeptidase and its gene
12/17/2003EP1371662A1 Novel variant of the cellular receptor LXR alpha
12/17/2003EP1371661A1 Variants of the Constitutive Activated of Retinoid acid response receptor (CAR) in its ligand binding domain (LBD)
12/17/2003EP1371660A1 Vaccine
12/17/2003EP1371377A1 Compositions for gene therapy of rheumatoid arthritis including a gene encoding an anti-angiogenic protein or parts thereof
12/17/2003EP1371375A1 Vaccine to protect animals against leishmania
12/17/2003EP1371373A1 Recombination super compound interferon used as hepatitis b surface antigen and e antigen inhibitor
12/17/2003EP1370870A2 Diagnostic screens for alzheimer's disease
12/17/2003EP1370696A2 Expression profiles and methods of use
12/17/2003EP1370694A2 Detection of methicillin-resistant staphylococcus aureus (mrsa)
12/17/2003EP1370692A2 Methods for purifying and detecting double stranded dna target sequences by triple helix interaction
12/17/2003EP1370691A2 Method for detecting cytosine methylation patterns having high sensitivity
12/17/2003EP1370689A1 Molecular target validation method
12/17/2003EP1370687A1 DETECTING BINDING OF mRNA TO AN OLIGONUCLEOTIDE ARRAY USING RNA DEPENDENT NUCLEIC ACID MODIFYING ENZYMES
12/17/2003EP1370685A2 Diagnosis of diseases associated with dna repair
12/17/2003EP1370684A2 Polynucleotides related to colon cancer
12/17/2003EP1370683A2 mRNA AMPLIFICATION
12/17/2003EP1370682A2 Assay for identifying inhibitors of the rna dependent rna polymerase (ns5b) of hcv
12/17/2003EP1370681A2 Methods using fluorescence energy transfer probes for detecting cleavage of nucleic acids