Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
09/2004
09/23/2004WO2003011209A8 Methods of sensitizing hepatocyte cell cultures to hepatitis infection, beads coated with hbv or hcv polypeptides and methods of using such beads to model viral infection or deliver substances into hepatocytes
09/23/2004WO2002101059A3 Transgenic plants synthesising high amylose starch
09/23/2004WO2002095003A3 Phytases, nucleic acids encoding them and methods for making and using them
09/23/2004WO2002086124A8 Human chemokine-13
09/23/2004US20040187178 Lentil plants having increased resistance to imidazolinone herbicides
09/23/2004US20040187177 Method to enhance agrobacterium-mediated transformation of plants
09/23/2004US20040187176 Methods for improving plant agronomical traits by altering the expression or activity of plant G-protein alpha and beta subunits
09/23/2004US20040187175 TPS plant gene constructs and transformants
09/23/2004US20040187174 Comprises expression vector coding cytochrome c promoter for use in transformation and controlling heterologous gene expression in rice, barley, wheat or maize
09/23/2004US20040187173 Preparing transgenic embryos via nuclear transfer of metaphase genetic material into enucleated oocytes; bioreactors and heterologous gene expression
09/23/2004US20040187172 Transgenic animal for screening therapeutic agents for brain tumors
09/23/2004US20040187171 Expression vectors comprising nucleotide sequences coding cytokines for tissue specific expression and treatment of skin disorders
09/23/2004US20040187170 Characterisation of gene function using double stranded RNA inhibition
09/23/2004US20040186287 heterocyclic imines such as 2-(2,6-difluorophenyl)-5-phenyl-3,4-dihydro-2H-pyrrole, formed by cyclocondensation, for use as insecticides or miticides
09/23/2004US20040186276 Proteins and DNA related to salt tolerance in plants
09/23/2004US20040186275 Sarcomere binding polypeptide for use in diagnosis and treatment of diabetes and cardiomyopathies; diuretics; vasodilation; antiarrhythmic agents
09/23/2004US20040186274 Methylation of histone h4 at arginine 3
09/23/2004US20040186071 Oligonucleotides or polynucleotides; screening for a drug candidate of an immunomodulator for CD40; reducing IL-12 cytokine production, treating inflammation disease; peptide nucleotide acid, modified nucleotides
09/23/2004US20040186070 Increased production of secreted proteins by recombinant eukaryotic cells
09/23/2004US20040186069 Antisense modulation of tumor necrosis factor receptor 2 expression
09/23/2004US20040186067 Vectors and methods for immunization or therapeutic protocols
09/23/2004US20040186053 Having a molecular weight of about 72 kDa, being a single chain protein with an N-terminal amino acid sequence of Leu Ala Pro Ser Pro Gln Ser Pro Glu Thr 1 5 10 Pro Ala [SEQ ID NO:16], and producing rapid inhibition of factor Xa in the presence of protein Z, calcium ions and cephalin.
09/23/2004US20040186051 Apo-2 ligand variants and uses thereof
09/23/2004US20040185567 Modification of plant genomes
09/23/2004US20040185566 Comprises nucleotide sequences coding serratia metalloprotease (SMP) for transformation and generation of parasite resistant plants; parasiticide; nematocide; biological pest control
09/23/2004US20040185565 High throughput system for producing recombinant viruses using site-specific recombination
09/23/2004US20040185563 Antigen presenting cells, method for their preparation and their use for cancer vaccines
09/23/2004US20040185562 Transforming cells with nucleotide sequences coding and expressing enzymatic polypeptides associated with biosynthesis of glucuronic, ascorbic and glucaric acids; bioreactors
09/23/2004US20040185559 Modulation of diacylglycerol acyltransferase 1 expression
09/23/2004US20040185556 Shuttle vector which utilizes homologous recombination to generate transgenic organism and express heterologus gene sequences; gene therapy and animal models
09/23/2004US20040185555 Viral vector coding lymphadenopathy associated antigens and devoid of early gene sequences for transfer and expression of heterologous gene sequences; vaccine development
09/23/2004US20040185546 enzyme inhibitor for selectin mediated binding events and methods of treating disease conditions using animal models; genetic engineering
09/23/2004US20040185541 Heterologous production of polyketides
09/23/2004US20040185533 Corticotropin-releasing factor2 receptors
09/23/2004US20040185528 Method for improved protein expression in bacteria by monitoring and modulating protein folding
09/23/2004US20040185527 Isolated human transporter proteins nucleic acid molecules encoding human transporter proteins and uses thereof
09/23/2004US20040185525 Process for producing peptide
09/23/2004US20040185508 Methods and reagents for modulating cholesterol levels
09/23/2004US20040185507 Isolated monoclonal antibody comprising a light and heavy chain variable of given sequence; diagnosing, treating and preventing prostate/colon cancer and renal carcinoma
09/23/2004US20040185504 Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization
09/23/2004US20040185503 Administering peroxisome proliferator-activated receptor agonist; assaying substance for up-regulating the expression of fatty acid-binding protein; glomerulonephritis, nephrotic syndrome, focal glomerulosclerosis
09/23/2004US20040185498 Novel cellulases, the genes encoding them and uses thereof
09/23/2004US20040185497 Method and kit for the screening, the detection and/or the quantification of transcriptional factors
09/23/2004US20040185496 Anti-bacterial methods and materials
09/23/2004US20040185493 kit with affinity-labeled primer-adapter molecules which allow improved isolation increasing both product recovery and speed of isolation
09/23/2004US20040185489 Gene transcription assay method
09/23/2004US20040185485 Gene markers useful for detecting skin damage in response to ultraviolet radiation
09/23/2004US20040185484 by fragmenting DNA; polishing the fragments' ends; ligating to universal adaptors, performing strand displacement and extension of the nicked fragments, purifying the double-stranded ligation products; solid phase synthesis
09/23/2004US20040185480 Method of treating surface of substrate used in biological reaction system
09/23/2004US20040185479 Modified oligonucleotides for use in gene modulation
09/23/2004US20040185476 antibody microarray for detecting incomplete deprotection of synthetic test oligonucleotides; high throughput assay; solid phase synthesis
09/23/2004US20040185474 Method of diagnosing depression
09/23/2004US20040185468 Promoter variants of the alpha-7 nicotinic acetylcholine receptor
09/23/2004US20040185466 to detect single nucleotide polymorphisms, genetic mutation, gene expression, forensic identification, disease association, DNA/genomic sequencing and translation/transcription analysis; solid phase synthesis
09/23/2004US20040185465 for diagnosing a disease in an animal or susceptibility to a disease related to an over-expression of a phosphodiesterase; for drug screening antiinflammatory agents
09/23/2004US20040185461 can be improved by providing stem-loop structures, in which the terminal regions (stems) cannot hybridize with any target polynucleotide that partially hybridizes with any other part of the structure; solid phase synthesis
09/23/2004US20040185460 kits for drug screening by gel-shift assay, western blot, phage-based expression cloning, co-fractionation by chromatography, co-precipitation, cross linking, interaction trap/two hybrid analysis, and enzyme linked immunosorbent assay (ELISA)
09/23/2004US20040185442 Novel polypeptide-human retinoic acid-responsive protein 53.57 and a polynucleotide encoding the same
09/23/2004US20040185441 obtained from Coleoptera having a luciferin-luciferase reaction by culturing transformant/transductant; genetic engineering
09/23/2004US20040185439 using polymorphisms to determine susceptibility cancer, osteoporosis, cardiovascular disorders; for drug screening
09/23/2004US20040185436 chimeric immunoglobulin for detecting hepatitis c viral (HVC) infections and/or contaminated blood products; diagnosis and viral diseases; kits
09/23/2004US20040185435 Molecular sequence of swine retrovirus and methods of use
09/23/2004US20040185431 for drug screening anticancer agents using animal model expression profiles; genetic engineering
09/23/2004US20040185146 Methods for producing sialyloligosaccharides in a dairy source
09/23/2004US20040185114 Starch encapsulation
09/23/2004US20040185060 Immunological enhancement agent comprising N-terminal peptide of p43 as an effective component
09/23/2004US20040185059 Biotin-binding receptor molecules
09/23/2004US20040185058 Immunogenic polypeptides physically linked; anticarcinogenic, antitumor, antiallergen, and viricidal agents; autoimmune diseases; systemic or mucosal vaccines; genetic engineering
09/23/2004US20040185056 Vaccines containing bovine herpesvirus 1 attenuated by mutation in latency-related gene
09/23/2004US20040185048 Modulation of IL-2- and IL-15-mediated T cell responses
09/23/2004US20040185038 loss of immunogenicity is achieved by amino acid substitution, addition or deletion, conducted at a position which in the non-modified polypeptide remains uncleaved by a protease of the MHC class II proteolytic pathway
09/23/2004US20040185033 Tumor antigens and CTL clones isolated by a novel procedure
09/23/2004US20040182706 Penetrating the cell membrane of the cell with a liquid-filled capillary; and applying electric current to the said capillary to propel the flow of the liquid inside the said capillary into the cell by electroosmosis
09/23/2004DE10311984A1 Using neutral endopeptidase-associated molecules for treatment, diagnosis, prophylaxis and monitoring of eating and metabolic disorders and dementia, also for drug development
09/23/2004DE10311399A1 New nucleic acid encoding inactive L-serine dehydratase, useful for improving bacterial synthesis of L-serine, is a deleted or mutated form of the wild-type sequence
09/23/2004DE10310261A1 Identifizierung von Antigen-Epitopen Identification of antigen epitopes
09/23/2004DE10310196A1 Verwendung eines trizyklischen Antidepressivums zur Förderung der Endozytose Use of a tricyclic antidepressant to promote endocytosis
09/23/2004DE10309856A1 Verfahren zur fermentativen Herstellung von S-Adenosylmethionin A process for the fermentative production of S-adenosylmethionine
09/23/2004DE10309557A1 Ein Translokationsenzym als Selektionsmarker A Translokationsenzym as a selection marker
09/23/2004DE10309555A1 New peptide chain release factor B, useful for improving recombinant protein production in bacteria, also a more active variant and related nucleic acids, vectors and cells, accelerates release of proteins from the ribosome
09/23/2004CA2557737A1 Insulin-like growth factor (igf-i) plasmid-mediated supplementation for therapeutic applications
09/23/2004CA2529819A1 Pegylated single domain antibodies
09/23/2004CA2523776A1 Baff mutants with at least one amino acid substitution and methods of their production
09/23/2004CA2519499A1 Phosphokinase assay
09/23/2004CA2519086A1 Biological molecule-immobilized chip and its use
09/23/2004CA2518944A1 Inhibitors of extracellular hsp90
09/23/2004CA2518912A1 Polypeptide compounds for inhibiting angiogenesis and tumor growth
09/23/2004CA2518907A1 Gene trap system
09/23/2004CA2518898A1 Nucleic acid compounds for inhibiting angiogenesis and tumor growth
09/23/2004CA2518811A1 Plant cells and plant bodies with modified cell growth, development and differentiation
09/23/2004CA2518787A1 Antibody against tumor specific antigen as target
09/23/2004CA2518782A1 Oligonucleotide mimetics
09/23/2004CA2518733A1 Production of plants with improved digestibility having an inactive peroxidase
09/23/2004CA2518552A1 Novel compositions and methods for the treatment of immune related disease
09/23/2004CA2518549A1 Soluble hybrid prion proteins and their use in the diagnosis, prevention and treatment of transmissible spongiform encephalopathies
09/23/2004CA2518475A1 Irna agents comprising asymmetrical modifications
09/23/2004CA2518417A1 Method for increasing resistance against stress factors in plants
09/23/2004CA2518275A1 Humanized antibodies that recognize beta amyloid peptide
09/23/2004CA2500521A1 Novel nucleic acids and polypeptides
09/22/2004EP1460134A1 SUGAR TRANSFERASE GnT-V HAVING ANGIOGENIC EFFECT