| Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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| 09/30/2004 | US20040192630 nucleic acid constructs containing a HexB encoding element and a HexA encoding element; used in the treatment of Tay-Sachs and Sandoff disease; delivering a vector to a brain cell |
| 09/30/2004 | US20040192629 Selectively inhibit the mutant while retaining wild-type gene expression to treat diseases caused by dominant mutants such as amyotrophic lateral sclerosis, Huntington's disease, Alzheimer's disease, and Parkinson's disease; administering to the cell an siRNA specific for the target allele |
| 09/30/2004 | US20040192628 gene expression inhibition of the kinase to prevent neovascularization, treat cancer |
| 09/30/2004 | US20040192627 Mitochondrial genome replenishment |
| 09/30/2004 | US20040192626 siNA molecule comprising a double-stranded structure that down-regulates expression of a target nucleic acid, wherein said siNA molecule does not require a 2'-hydroxyl group containing ribonucleotide; treating viral diseases such as SARS (severe acute respiratory syndrome virus), herpes, hepatitis, HIV |
| 09/30/2004 | US20040192610 For treating disorders regulated at neuronal nicotinic acetylcholine receptors, including cardiovascular disorders, gastric motility disorders, urinary incontinence, nicotine addiction, mood disorders and small cell lung carcinoma |
| 09/30/2004 | US20040192607 Transcriptional regulation of the human beta3-adrenergic receptor gene |
| 09/30/2004 | US20040192589 Production of high molecular mass lectins |
| 09/30/2004 | US20040192588 Pharmaceutical compositions comprising modified cns-derived peptides for promoting nerve regeneration and prevention of nerve degeneration |
| 09/30/2004 | US20040191912 New constitutive plant promoter |
| 09/30/2004 | US20040191911 Method for altering degradation of engineered protein in plant cells |
| 09/30/2004 | US20040191910 Genes encoding plant transcription factors |
| 09/30/2004 | US20040191905 Modulation of HIV replication by RNA interference |
| 09/30/2004 | US20040191904 Antisense modulation of src-c expression |
| 09/30/2004 | US20040191901 Insulin producing cells derived from human embryonic stem cells |
| 09/30/2004 | US20040191898 Trangenic diploid cell comprising mutation in kinase allele for use in screening modulator for treatment of anxiety, addiction, withdrawal syndrome, skeletal muscle spasms, convulsive seizures and epilepsy |
| 09/30/2004 | US20040191884 Photoprotein derived from okinawan squid and gene encoding the photoprotein |
| 09/30/2004 | US20040191883 Comprises water soluble glucose dehydrogenase associated with pyrroloquinoline quinine as a coenzyme for use as diagnostic tool in bioassay for monitoring blood glucose concentration |
| 09/30/2004 | US20040191876 Bacterium having ability to produce L-glutamic acid, L-proline or L-arginine and method for producing L-glutamic acid, L-proline or L-arginine |
| 09/30/2004 | US20040191875 Method for producing target substance |
| 09/30/2004 | US20040191873 Determining transcription profile for cell with simultaneous identification of intron/exon boundaries; functional genomics and transcriptomics |
| 09/30/2004 | US20040191872 Using oligonuclelotide immobilized columns, RNA polymerase and cleavage enzyme to prepare preferential nucleotide sequences |
| 09/30/2004 | US20040191871 Method for plasmid preparation by conversion of open circular plasmid |
| 09/30/2004 | US20040191870 Methods of 6-0 sulfating polysaccharides and 6-0 sulfated polysaccharide preparations |
| 09/30/2004 | US20040191869 Recombinant vector coding cytochrome bo3 ubquinol oxidase fusion for use as tool in determining three dimensional structure of primary protein and fused partner domains; drug sceening and delivery |
| 09/30/2004 | US20040191867 DNA sequences coding for a mammalian glucuronyl C5-epimerase and a process for its production |
| 09/30/2004 | US20040191866 Attenuated microorganisms for the treatment of infection |
| 09/30/2004 | US20040191865 Using transgenic cells for propagation of heterologous proteins; bioreactors |
| 09/30/2004 | US20040191864 Methods for producing biological substances in enzyme-deficient mutants of Aspergillus |
| 09/30/2004 | US20040191863 Mutations affecting plasmid copy number |
| 09/30/2004 | US20040191861 Preparing transgenic cells and inducing expression of heterologous sequences; tissue engineering and in vitro translation |
| 09/30/2004 | US20040191851 Methods for the identification of inhibitors of lipid transfer protein activity in plants |
| 09/30/2004 | US20040191850 Nucleic acid molecules encoding proteins essential for plant growth and development and uses thereof |
| 09/30/2004 | US20040191847 Kit for diagnosing gaucher disease in humans and animals |
| 09/30/2004 | US20040191840 Using immunoglobulins to inactivate viricidal and antitumor activities of huma n type interferon for preventing autoimmunity and graft rejection; immunosuppressants |
| 09/30/2004 | US20040191839 Methods for sorting undifferentiated cells and uses thereof |
| 09/30/2004 | US20040191829 Comprises peptide associated with sugar transport protein for identifying modulators for treatment and prevention of cell proliferative disorder |
| 09/30/2004 | US20040191827 Modulators of the hypocretin system and methods of screening therefor |
| 09/30/2004 | US20040191826 Dipeptidyl peptidases |
| 09/30/2004 | US20040191825 Using pyrococcus polymerase fusion to replicate preferential nucleotide sequences; polynucleotide amplification tool; genetic engineering |
| 09/30/2004 | US20040191816 Microarray for propagation of preferential nucleotide sequences for subsequent transformation into animal cells; forensics; medicine and epidemiology; public health and prediction, diagnosis and prevention of disease |
| 09/30/2004 | US20040191811 Methods for measuring levels of uridine-diphosphate-N-acetylglucosamine and activity of inhibitors thereof |
| 09/30/2004 | US20040191808 Reagents for oligonucleotide cleavage and deprotection |
| 09/30/2004 | US20040191806 Assays using crosslinkable immobilized nucleic acids |
| 09/30/2004 | US20040191805 Nucleotide sequences coding g-protein coupled receptors for identifying modulators of sweet taste transduction; sweetners and flavoring; tastands and food treatment |
| 09/30/2004 | US20040191800 Comprises nucleotide sequences coding protein which controls thermogenesis in human skeletal muscle and heart for prevention and treatment of obesity, cachexia, cardiovascular and muscular disorders |
| 09/30/2004 | US20040191799 Method for plasmid preparation by conversion of open circular plasmid |
| 09/30/2004 | US20040191796 8-(3-{[bis(methylethyl)amino](2-cyanoethoxy)phosphinooxy}propyl)- 7-oxophenoxazin-3-yl 2,2-dimethylpropanoate; improves signal to noise ratios and other advantageous characteristics in hybridization and related assays |
| 09/30/2004 | US20040191794 Method for the determination of multiple analytes |
| 09/30/2004 | US20040191791 Comprises nucleotide sequences coding sodium voltage gated channels for identifying modulators for treatment of epilepsy; diagnosis of seizure disorders |
| 09/30/2004 | US20040191790 Comprises activator polypeptide which confers heat resistance and stability to polygalacturonase; identifying modulators which decrease or increase pectin degradation in fruit juices |
| 09/30/2004 | US20040191788 Method of encoding information in nucleic acids of a genetically enginerred organism |
| 09/30/2004 | US20040191787 Leucoanthocyanidin reductase (LAR) polypeptide for modifying the pasture quality of legumes and producing bloat-safe forage crops with enhanced nutritional value, disease/pest resistance and malting qualities |
| 09/30/2004 | US20040191785 Methods for diagnosing individuals with an increased risk to develop a deficiency based on mdr1 gene polymorphism |
| 09/30/2004 | US20040191782 Evaluating colon tumors for recurrence via differential gene expression of tumor antigen genes in bowel cell walls; cancer diagnosis and treatments; antitumor agents |
| 09/30/2004 | US20040191781 Genomic profiling of regulatory factor binding sites |
| 09/30/2004 | US20040191779 Statistical analysis of regulatory factor binding sites of differentially expressed genes |
| 09/30/2004 | US20040191777 Apparatus and methods for isolating droplet dispensing devices |
| 09/30/2004 | US20040191773 Oligoribonucleotides and ribonucleases for cleaving RNA |
| 09/30/2004 | US20040191772 Method of shuffling polynucleotides using templates |
| 09/30/2004 | US20040191768 Process for typing of HCV isolates |
| 09/30/2004 | US20040191767 Comprises nucleotide sequences coding hepatitis core protein fusion for generating vaccine to prevent infcetion and treat liver dysfunction; gene therapy and cell-mediated immune response |
| 09/30/2004 | US20040191763 HBV mutations associated with reduced susceptibility to adefovir |
| 09/30/2004 | US20040191762 Method for purification of viral vectors having proteins which bind sialic acid |
| 09/30/2004 | US20040191761 Modified adenoviral E1A constructs and methods of use thereof |
| 09/30/2004 | US20040191756 Transgenic rodent for diagnosing and identifying modulator for treatment and prevention inflammatory disorders |
| 09/30/2004 | US20040191273 Methods and compositions for obtaining disease protection for economically important animals |
| 09/30/2004 | US20040191272 Methods and reagents for vaccination which generate a CD8 T cell immune response |
| 09/30/2004 | US20040191261 Genetically engineered fusion protein comprising fibrin/fibrinogen binding moiety such as endothelial growth factor (VEGF165) C-terminal domain fused to a wound healing agent such as leptin |
| 09/30/2004 | US20040191259 Nucleotide sequences coding immunoglobin for use in detection and prevention of hepatitis b viral infections; genetic vaccines |
| 09/30/2004 | US20040191235 Method for obtaining antigen-specific tr1 regulatory lymphocytes |
| 09/30/2004 | US20040191233 Bifidobacteria and siderophores produced thereby and methods of use |
| 09/30/2004 | US20040191230 Pharmaceutical composition for the diagnosis, prevention or treatment of a tumoral pathology comprising an agent modulating the polymerization state of actin |
| 09/30/2004 | US20040191228 Methods of kidney transplantation utilizing developing nephric tissue |
| 09/30/2004 | US20040191223 Combinatorial methods for inducing cancer cell death |
| 09/30/2004 | US20040191222 Adenovirus serotype 34 vectors, nucleic acids and virus produced thereby |
| 09/30/2004 | US20040191221 Delivering heterologous gene to a periosteal cell of a mammal; gene expression; bone disorders, osteoarthritis and osteoporosis; antiinflammatory agents |
| 09/30/2004 | US20040191173 Metastasis models using green fluorescent protein (GFP) as a marker |
| 09/30/2004 | US20040188353 Novel separation agent for separating optical isomer and method for preparation thereof |
| 09/30/2004 | DE10312842A1 Thermisch stabile Amidasen Thermally stable amidases |
| 09/30/2004 | DE10309985A1 New nucleic acids, and encoded proteins, from prostatic cancer tissue, useful for diagnosis, treatment and in screening for specific binding agents |
| 09/30/2004 | CA2855229A1 Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure |
| 09/30/2004 | CA2790689A1 Fvii or fviia variants |
| 09/30/2004 | CA2524255A1 Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure |
| 09/30/2004 | CA2522786A1 Gene therapy vectors having reduced immunogenicity based on cd8 alpha-chain |
| 09/30/2004 | CA2519863A1 Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure |
| 09/30/2004 | CA2519860A1 Short interfering rna (sirna) analogues |
| 09/30/2004 | CA2519620A1 Humanized anti-cd4 antibody with immunosuppressive properties |
| 09/30/2004 | CA2519457A1 Compounds and their use for specific and simultaneous inhibition of genes involved in diseases and related drugs |
| 09/30/2004 | CA2519397A1 Reduced stature plants |
| 09/30/2004 | CA2519071A1 Targeted and regional cellular ablation in zebrafish |
| 09/30/2004 | CA2519027A1 Agent comprise an albumin-like first polypeptide bound to a second polypeptide |
| 09/30/2004 | CA2518980A1 Antibodies to igf-i receptor for the treatment of cancers |
| 09/30/2004 | CA2518926A1 Adenovirus serotype 24 vectors, nucleic acids and virus produced thereby |
| 09/30/2004 | CA2517283A1 Relaxin3-gpcr135 complexes and their production and use |
| 09/30/2004 | CA2517186A1 Regulation of cell surface proteins |
| 09/30/2004 | CA2464894A1 Colorectal cancer prognostics |
| 09/29/2004 | EP1462528A1 Nucleic acid immobilization and use as a biosensor |
| 09/29/2004 | EP1462525A1 siRNA EXPRESSION SYSTEM AND PROCESS FO RPRODUCING FUNCTIONAL GENE KNOCKDOWN CELL OR THE LIKE USING THE SAME |
| 09/29/2004 | EP1462524A1 Cellulase preparations containing reducing agent and method of processing fiber |