Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
12/2004
12/09/2004US20040248175 Embryogenic regulatory protein for use in diagnosis, prevention and treatment of cell proliferative and reproductive disorders
12/09/2004US20040248174 Small interfering RNA sequences for use in prevention and treatment of vision defects, inflammation, cardiovascular and cell proliferative disorders; RNA interference; gene expression inhibition
12/09/2004US20040248173 Nucleotide sequences coding cyclic peptide receptor for use in identifying modulators for treatment of pituitary hormone, epinephrine release, gastrointestinal, cardiovascular, electrolyte balance, hypertensive, diabetic and respiratory system disorder
12/09/2004US20040248171 Using hypermethylation of regulatory protein gene sequences has diagnostic indicator of breast, lung and colon cancers
12/09/2004US20040248168 Nucleotide sequences coding homeodomain-interacting protein kinase (HIPK) for use as tool in identifying antisense agent for use in treatment of nervous system and brain disorders
12/09/2004US20040248167 Multicompartment apparatus for the rapid detection of DNA, proteins and viruses
12/09/2004US20040248165 Nucleic acid immobilization method and manufacturing method of biosensor using same
12/09/2004US20040248164 Preparing microarray comprised of short hairpin looped RNA molecules for use in monitoring gene expression in mammalian cells; high throughput assay for use in functional genomics; post transcriptional gene silencing
12/09/2004US20040248162 Releasable polymer arrays
12/09/2004US20040248159 Plant farnesyltransferases
12/09/2004US20040248155 Novel oncogene, recombinant protein derived therefrom, and uses thereof
12/09/2004US20040248154 Hormone transcription factor for use in identifying tissue-selective estrogens and controlling heterologous gene expression
12/09/2004US20040248153 Determining linkage realtionships between preferential genes along a chromosome; genetic engineering and linkage relationships
12/09/2004US20040248149 Nucleotide sequences coding G-protein coupled receptor (T2R) for use in identifying modulators which control bitterness; food processing and pharmocological design
12/09/2004US20040248148 Ultrasensitive detection of pathogenic microbes
12/09/2004US20040248145 Using vector transformation to generate transgenic cells which overexpress an enzyme which specifically digests RNA/DNA hybrids; gene expression inhibition via nuclease digestion and antisense oligonucleotide exposure
12/09/2004US20040248143 Generating novel polypeptides via non-stochastic polynucleotide site-saturation mutagenesis; protein bioengineering
12/09/2004US20040248142 Method for detecting hepatocellular carcinoma
12/09/2004US20040248141 Transgenic cell comprising nucleotide sequences which form triplex structures for use in diagnosis, prevention and treatment of skin, pigmentation and cell proliferative disorders
12/09/2004US20040248140 Nucleotidic sequences having activity of controlling translation efficiency and utilization thereof
12/09/2004US20040248137 Human and mammalian stem cell-derived neuron survival polypeptides
12/09/2004US20040248133 Method for determining cell cycle position
12/09/2004US20040248132 Regulatory sequences which control expression from seven in absentia homologue-1(siah-1) and death receptor 5 (DR5) for use in identifying modulators of apoptosis and cell proliferative; antitumor agents
12/09/2004US20040248131 Methods for dna mutagenesis and dna cloning
12/09/2004US20040248130 Nucleic acid extraction device
12/09/2004US20040248129 Neural polypeptide for use as tool in identifying modulators for controlling body weight; treating obesity
12/09/2004US20040248126 Method of detecting toxic substance
12/09/2004US20040248124 Nucleic acid encoding polypeptide involved in cellular entrance of the prrs virus
12/09/2004US20040248123 Membrane protein receptor for use in identifying modulator of taste; point mutations; antibodies; food processing and bitterness; phenotype analysis
12/09/2004US20040248122 Comprises substrate presenting reflecting main surface with localized sites (containing halogen, silane, or silanol groups) which are sensitive to fluorescence detection by transparent layer; microarrays; improved fluorescence
12/09/2004US20040248121 Transgenic myocytes as tool in monitoring myostatin inhibitory activity on gene expression; tissue and musle regeneration; diagnosing and treating muscle disorders
12/09/2004US20040248119 Dna fragments containing gene having function relating to autonomous proliferation of plasmid
12/09/2004US20040248115 Nucleotide sequence probes for detecting beer-spoilage lactic acid bacteria; food processing and alcoholic beverages
12/09/2004US20040248114 Novel maxizyme
12/09/2004US20040248113 Expression vector comprising immunoglobulin sequences for treatment and prevention of infections and cell proliferative disorders; minigene vaccines; immunotherapy
12/09/2004US20040248110 Random truncation and amplification of nucleic acid
12/09/2004US20040248109 Methods for selecting protein binding moieties
12/09/2004US20040248102 Replicating RNA sequences using template mediated primer extension; preparing labeled nucleic acid for monitoring differential gene expression
12/09/2004US20040248101 Identification of novel antibacteria agents by screening the single-stranded DNA expression library
12/09/2004US20040248099 Calcium-activated potassium channels; 1,4-dihydropyridine-3,5-dicarboxylic acid derivatives act as inhibitors; gene knockout; skin disorders; psoriasis; wound healing
12/09/2004US20040248098 Using rearrangements in microsatellite sequences (numbers present) detected via variation in mass to charge ratio to identify genomic polymorphism
12/09/2004US20040248091 Novel polypeptide-human g-protein and the polynucleotide encoding the same
12/09/2004US20040248088 Novel g protein-coupled receptor up-regulated in prostate cancer and uses thereof
12/09/2004US20040248087 Using specific oligonucleotide primers to enrich isothermal amplification reaction products with preferential nucleotide sequences; DNA amplification
12/09/2004US20040248083 Viral plasmid comprising heterologous or synthetic dimerisation sequences which promotes dimer formation of plasmid transcripts and prevents recombination between plasmid transcripts and another retrovirus present in genome; gene transfer tool; bioreactor
12/09/2004US20040247680 Targeted delivery of controlled release polymer systems
12/09/2004US20040247661 injectable liposomal composition for delivery of large amounts of water-soluble substance comprises a plurality of liposomal vesicles having a high weight ratio of lipid to encapsulated water-soluble substance which is distributed over the liposomal vesicles; high efficiency of encapsulation
12/09/2004US20040247621 Combination therapy using a synergistic mixture of mechlorethamine, nitrogen mustard N-oxide, melphalan, uramustin, ifosfamide, chlorambucil, or cyclophosphamide and an anti-interleukin-6 receptor antibody; anticarcinogenic agents
12/09/2004US20040247620 Genetic transduction for improved exogenous gene expression of epothilones in a modified host cell
12/09/2004US20040247616 Homologous 28-kilodalton immunodominant protein genes of Ehrlichia canis and uses thereof
12/09/2004US20040247615 A nucleic acid comprising a nucleotide sequence encoding a Met-NS3-NS4A-NS4B-NS5A-NS5B polypeptide containing an inactive NS5B RNA-dependent RNA polymerase region; adenovector or DNA plasmid vaccine; cultured cells expressing the nucleic acid; vaccination
12/09/2004US20040247613 A nucleic acid expression vector encodes the catalytic subunit of human telomerase reverse transcriptase (hTRT); immunostimulants; anticarcinogenic agents; gene therapy
12/09/2004US20040247601 Methods for diagnosing cancer and decreasing metastasis by cancer cells
12/09/2004US20040247600 Agent that specifically binds to human MTAP protein in an embedded biological sample, especially a polyclonal antibody or a monoclonal antibody produced by hybridoma cell line ATCC Accession No. PTA-5001
12/09/2004US20040247595 Related to the potassium channel subfamily; can be used as models for the development of and aid in the identification of therapeutic proteins that modulate transporter activity
12/09/2004US20040247585 Recombinant alpha-galactosidase a therapy for fabry disease
12/09/2004US20040247583 Capable of producing d-pseudoephedrine by acting on l-2-methylaminopropiophenone; a nucleic acid coding the enzyme, a microorganism producing the enzyme, and producing an optically active aminoalcohol using them
12/09/2004US20040247578 Administering into or near a site of a tumor or infectious lesion an antigen presenting cell, especially a dendritic cell, and an immunostimulatory cytokine or a nucleic acid encoding an immunostimulatory cytokine
12/09/2004US20040247572 Hair follicle-reconstitution system and animal carrying the same
12/09/2004US20040247564 Treating a tissue disorder involving a loss and/or apoptosis of cells by administering an agent that induces phosphorylation and/or activation of protein kinase B to cause proliferation; particularly administering a human stromal-derived factor-1 and a G-CSF to cause proliferation of cardiomyocytes
12/09/2004US20040247562 Diagnostic and prognostic method for cancer based on skipping of the exon 3 region of the G-CSF gene at mRNA or protein levels
12/09/2004US20040245317 Artificial chromosomes that can shuttle between bacteria yeast and mammalian cells
12/09/2004US20040245209 Covering a catalyst thin film with a supramolecule thin film; self-assembling by annealing; selectively staining with a metal compound and etching an unstained portion using stained film as a mask to form stained supramolecule nanopattern and using it to form a nanopattern of the catalyst by ion-milling
12/09/2004US20040245163 Purification device for ribonucleic acid in large volumes, and method
12/09/2004US20040244714 Methods for growing and imprinting fish using an odorant
12/09/2004US20040244623 Printed materials comprising a support having an oligomer and/or a polymer applied thereon, a method for preparing the same and a method for delivering and/or storing the same
12/09/2004DE10314413A1 Verfahren zum Nachweis der Expression rekombinanter Proteine an einer Zelloberfläche und zur Immobilisierung und Aufreinigung von Zellen und Proteinen A method for detecting the expression of recombinant proteins on a cell surface and for immobilization and purification of proteins and cells
12/09/2004DE102004019852A1 New modified sarcosine oxidase, useful for assaying creatinine, e.g. for diagnosis of kidney disease, has improved stability under acidic conditions, also new DNA that encodes it
12/09/2004CA2527907A1 Double-stranded hairpin rnas for rnai
12/09/2004CA2527819A1 Optical sensors based on hybrid aptamer/conjugated polymer complexes
12/09/2004CA2527722A1 Biodegradable poly(beta-amino esters) and uses thereof
12/09/2004CA2527571A1 Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
12/09/2004CA2527429A1 Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions using various agents
12/09/2004CA2527301A1 Oligonucleic acid-bearing composite and pharmaceutical composition containing the composite
12/09/2004CA2527216A1 Process for obtaining plasmid dna by means of an aqueous 2-phase system
12/09/2004CA2527115A1 Wheat plants having increased tolerance to imidazolinone herbicides
12/09/2004CA2527109A1 Oligo double-stranded rna inhibiting the expression of bcl-2 and medicinal composition containing the same
12/09/2004CA2526695A1 Selection of allosteric regulators with class iii g protein-coupled receptors depleted of the extracellular domain
12/09/2004CA2526083A1 Complement inhibitors
12/09/2004CA2525853A1 Method for cloning in the rat by nuclear transfer
12/09/2004CA2525717A1 Gitr ligand and gitr ligand-related molecules and antibodies and uses thereof
12/09/2004CA2525540A1 Enterococcus antigens
12/09/2004CA2524454A1 Enzyme with xylanase activity at acidic ph
12/09/2004CA2523716A1 Human anti-human cd3 binding molecules
12/09/2004CA2521331A1 Novel il-8-like polypeptides
12/08/2004EP1484699A2 Protein design automation for protein libraries
12/08/2004EP1484415A2 Method of alleviating pest infestation in plants
12/08/2004EP1484412A2 Eukaryotic host cell line in which an endogenous gene has been activated, and uses thereof
12/08/2004EP1484411A1 Stress resistant plant
12/08/2004EP1484410A1 Fermentation methods and genetically modified bacteria with increased substrate and byproduct uptake.
12/08/2004EP1484409A2 Expression vector comprising short-lived drug resistance gene
12/08/2004EP1484408A1 Human kinase proteins and polynucleotides encoding the same
12/08/2004EP1484407A1 Method of controlling ethanol production and mass production of lactic acid and transformant therefor
12/08/2004EP1484405A1 Nucleic acid fragments and polypeptide fragments derived from M. Tuberculosis
12/08/2004EP1484404A1 Immunogenic detoxified mutants of cholera toxin and of the toxin LT, their preparation and their use for the preparation of vaccines
12/08/2004EP1484403A1 Gene participating in the synthesis of brassinosteroid
12/08/2004EP1484402A2 Antibody for use in therapy
12/08/2004EP1484401A1 Secreted polypeptides and corresponding polynucleotides
12/08/2004EP1484400A1 Sodium-independent transporter carrying acidic amino acid and its gene
12/08/2004EP1484399A1 Mouse spermatogenesis genes, human male sterility-associated genes and diagnostic system using the same