Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
12/2004
12/16/2004US20040253707 Novel cathepsins L-like cysteine protease derived from northern shrimp (Pandalus eous)
12/16/2004US20040253706 Substrates and assays for beta-secretase
12/16/2004US20040253704 Plasmid comprising nucleotide sequences coding poly- gamma -glutamate synthetase for use in developing vaccine for prevention and treatment of bacillus infection
12/16/2004US20040253703 Novel aminopeptidase derived from bacilius licheniformis, gene encoding the aminopeptidase, expression vector containing the gene, transformant and method for preparation thereof
12/16/2004US20040253701 Protein and peptide fragments from mouse telomerase reverse transcriptase
12/16/2004US20040253700 Expression vector comprising nucleotide sequences coding adenosine triphosphatase for use in improving organismal energy metabolism
12/16/2004US20040253699 Insect inhibitory lipid acyl hydrolases
12/16/2004US20040253698 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
12/16/2004US20040253697 Nucleotide sequences coding epothilone polyketide synthase for use in generating fungicides, immunosuppressants and/or antitumor agents in microorganisms; bioreactors and heterologous gene expression
12/16/2004US20040253695 Using enone reductase to generate optically active intermediates for use in the synthesis of pharmaceuticals
12/16/2004US20040253693 Methods for the biosynthesis of polyesters
12/16/2004US20040253688 Using transposon regulatory element as tool in cloning and expxression of heterologous nucleotide sequences; bioreactors
12/16/2004US20040253687 Using multicompartment apparatus and affinity chromatography to isolate/purify preferential protein from cell solutions
12/16/2004US20040253686 Novel human kunitz-type inhibitors and methods relating thereto
12/16/2004US20040253685 eNOS mutations useful for gene therapy and therapeutic screening
12/16/2004US20040253684 Nucleotide sequences coding mambrane associated guanylate kinase for use in treatment and prevention of nervous system, blood, sleep and behavioral disorders
12/16/2004US20040253682 Immunloglobulin prostaglandin inhibitor for use in the treatment and prevention of arthritic and inflammatory bowel disorders
12/16/2004US20040253681 Mitogenic oxygenase regulators
12/16/2004US20040253676 Method for producing sweetners and alcohol
12/16/2004US20040253675 Method for GPCR assay with a coexpressed Galpha protein
12/16/2004US20040253674 Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR)
12/16/2004US20040253671 Isolating hexose oxidase for use as tool in enhancement of nutrient quality of animal feeeds
12/16/2004US20040253670 Using eschericia as bioreator for production of pasturella galactosyltransferase for use in processing sugars for use as components of pharmeceuticals
12/16/2004US20040253669 Regulation of human dcamkl1-like serine/threonine protein kinase
12/16/2004US20040253668 Expression vector comprising nucleotide sequences coding membrane protein for use identifying modulators for treatment of cell proliferative, respiratory, nervous system, autoimmune and inflammatory disorders
12/16/2004US20040253667 Expression vector comprising nuclelotide sequences coding membrane protein for use in identifying modulator for treatment of cell proliferative, nervous system and inflammatory diseases
12/16/2004US20040253666 Secreted and transmembrane polypeptides and nucleic acids encoding the same
12/16/2004US20040253663 Genes encoding carotenoid compounds
12/16/2004US20040253655 Immunoassay for use in detection high blood pressure; immunodiagnostics
12/16/2004US20040253654 Streptococcus uberis adhesion molecule
12/16/2004US20040253651 Detected from secreted glycoprotein (such as matrix metalloproteinases, prostate specific antigen, kallikrein 2, human chorionic gonadotrophin or carcinoembryonic antigen); glycosyltransferases; for diagnosing and targeting cell proliferative disorders; vaccines
12/16/2004US20040253647 Evaluating modulators effectiveness as treatment for alzheimer's via quantifying amyloid precursor protein peptide cleavage products present after exposure agonist/antagonist
12/16/2004US20040253645 Monoclonal antibody with enhanced species preference; immunotherapy
12/16/2004US20040253643 Using ratio of neurofibrillary tangle to amyloid beta protein in cerebrospinal fluid as diagnostic indicator of nervous system disorders; immunodiagnostics
12/16/2004US20040253635 Contacting libraries with tag (green/blue fluorescent protein, horseradish peroxidase) to form complex, incubating, then identifying competitive binding agents
12/16/2004US20040253631 Expression vector comprising topisomerase site-specific recombination sequences for use as gene transfer and propagation tools in bioreactors; gene therapy; protein and gene expression analysis
12/16/2004US20040253629 Expression vector comprising nucleotide sequences coding bcl-2-related ovarian killer (BOK) for use as diagnostic/investigative tool in elucidating mechanisms of apoptopsis, specifically in reproduction; antiproliferative agents
12/16/2004US20040253623 Nucleic acid binding proteins
12/16/2004US20040253621 Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts
12/16/2004US20040253620 Using insertional events to transfer genetic material to cells, expressing nucleotide sequences, translating products and identifying allelic variants via electrophoretic separation
12/16/2004US20040253617 Using capsular polysaccharide gene (CPS) sequences to classify streptococcal serotypes; diagnosis and treatment of infection
12/16/2004US20040253614 Multicompartment device comprising microarrays which utilizes computer imaging to monitor and analyze genetic hybridization events in liquids; computer diagnostic imaging
12/16/2004US20040253612 Selection of proteins using RNA-protein fusions
12/16/2004US20040253611 Immunologically active proteins from borrelia burgdorferi
12/16/2004US20040253610 Expression vector comprising nucleotide sequences coding tumor necrosis factor receptor protein (TWEAK) for use in identifying modulators for treatment of inflammatory, cardiovacullar, vision and cancer disorders
12/16/2004US20040253607 Transgenic cells comprising recombinant vectors which code and express bacterial cell surface protein for use tools in identifying affinity binding reagents; high throughput assay
12/16/2004US20040253604 Artificial intron for use in treatment and prevention of viral infection; gene expression inhibition
12/16/2004US20040253603 Using dextran sulfate as volume exclusion agent for enhancing hybridization; automated in situ/vitro hybridization
12/16/2004US20040253602 Therapeutic and diagnostic methods and compositions based on jagged/notch proteins and nucleic acids
12/16/2004US20040253599 Novel protein, its dna and use thereof
12/16/2004US20040253595 P53-dependent apoptosis-inducing protein and method of screening for apoptosis regulator
12/16/2004US20040253591 Compositions and methods for making mutations in cell lines and animals
12/16/2004US20040253590 Compositions and methods for making mutations in cell lines and animals
12/16/2004US20040253589 Compositions and methods for making mutations in cell lines and animals
12/16/2004US20040253588 Cytochrome p450 monooxygenase for use in identifying modulators for treatment, diagnosis and prevention of autoimmune/inflammatory, cell proliferative, developmental, endocrine, eye, metabolic, gastrointestinal and liver disorders
12/16/2004US20040253586 Plastid transformation
12/16/2004US20040253585 Methods of detecting polynucleotide kinase and its use as a label
12/16/2004US20040253584 Method for separating nucleic acids into populations
12/16/2004US20040253581 Transgenic animals expressing transdominant negative retroviral nucleic acids and proteins
12/16/2004US20040253578 Solid support comprising immobilized dynamic action reference tools (DART)/bioconjugates for use in isolation and analysis of nucleic acids and polypeptides; drug screening
12/16/2004US20040253574 Method for producing ready to use, antigen loaded or unloaded, cryconserved mature dendritic cells
12/16/2004US20040253303 Biodrugs contains carrier capable of introducing the isolated DNA molecule into a mammalian cell; ANTITUMOR AGENTS, VIRICIDES, BACTERICIDES; GENE EXPRESSION BY IMMUNOCOMPETENT CELLS; AUTOIMMUNED DISEASE TREATMENT; SIDE EFFECT REDUCTION
12/16/2004US20040253273 Recombinant influenza viruses expressing tumor-associated antigens as antitumor agents
12/16/2004US20040253272 Process for producing inactivated virus envelopes
12/16/2004US20040253270 Nucleic acid encoding infectious, nonpathogenic porcine circovirus type-1(PCV1), which contains immunogenic open reading frame gene of pathogenic PCV2 in place of an ORF gene of PCV1 nucleic acid molecule; means of protecting pigs against viral infection or postweaning multisystemic wasting syndrome
12/16/2004US20040253250 Compositions and methods for regulating lymphocyte activation
12/16/2004US20040253247 Conjugate comprising a peptide having an engineered amino acid sequence capable of binding a plasma protein, said peptide conjugated to the therapeutic or diagnostic substance, wherein elimination half time of conjugate exceeds that of unconjugated therapeutic or diagnostic substance; peptide ligands
12/16/2004US20040253245 Modulating an immune response by administering a modulator of Notch intracellular domain protease activity, including modulators of presenilin and presenilin-dependent gamma secretase activity; immunotherapy; treatment of Alzheimer's disease
12/16/2004US20040253239 nucleotide sequences that code angiogenic factor antagonists and vascular endothelial structure regulators, used for prevention of angoigenesis or cancer; gene therapy
12/16/2004US20040253234 DNA sequences that code antibodies or fragments; genetic vectors and host cells transformed by the vector, used for diagnosis and prophylaxis of cancer
12/16/2004US20040253233 genetic engineered chimeric and humanized antibodies obtained from murine monoclonal antibody P3 (MAb P3) and its antiidiotypic antibodies, used as antitumor agents
12/16/2004US20040253231 monoclonal or polyclonal antibodies having specific reactivity with adenosine triphosphate binding domains, caspase recruitment domains and triosephosphate isomerase domain peptides, used for modulation of apoptosis
12/16/2004US20040253224 genetically engineered hydrolase enzymes comprising amino acid sequence having chitinase activity, used for treating respiratory system disorders such as cystic fibrosis, chronic obstructive pulmonary disease, asthma, bronchitis or tuberculosis
12/16/2004US20040253221 Novel pla1
12/16/2004US20040253216 Activated checkpoint therapy and methods of use thereof
12/16/2004US20040253215 Methods and compositions for treating disorders
12/16/2004US20040253214 fusing cells; nucleic acid vector comprises a nucleotide sequence encoding a measles virus F glycoprotein and a nucleotide sequence encoding a chimeric measles virus H glycoprotein; nucleotide sequence encoding a syncytium-inducing polypeptide expressible on a eukaryotic cell surface
12/16/2004US20040253211 analyzing the expression of claudin-3, claudin-4 and claudin-9; if these genes are under-expressed, the transformed/cancerous cell is a metastatic cell; nucleic acid is transfected into the cancerous cell
12/16/2004US20040253210 replication-defective adenovirus type 7 that expresses one or more HIV polypeptides for use in stimulating an immune response to HIV-1; adenovirus serotype 7 cosmid vector; gene therapy
12/16/2004US20040253141 Apparatus and method for nucleic acid spatial ordering
12/16/2004DE10322912A1 Verfahren zum Nachweis von Nukleinsäuren A method for detecting nucleic acids
12/16/2004CA2536472A1 Epas1 gene transfer to improve cell therapy
12/16/2004CA2531569A1 Composition for stabilizing survival of transplanted hematopoietic stem cell, kit for obtaining the composition, method of stabilizing survivial of transplanted hematopoietic stemcell, human monoclonal antibody or human polyclonal antibody and method of producing the same, gene encoding human monoclonal antibody and transformation introducing the gene
12/16/2004CA2529061A1 Antimicrobial polypeptides
12/16/2004CA2528851A1 Extracellular aspergillus polypeptides
12/16/2004CA2528500A1 Porcine cmp-n-acetylneuraminic acid hydroxylase gene
12/16/2004CA2528408A1 Plant transformation and selection
12/16/2004CA2528252A1 Methods and kits for mass production of dsrna
12/16/2004CA2528131A1 Nucleotides for prevention and treatment of bacterial and fungal pathologies
12/16/2004CA2528088A1 Method for diagnosing cancer and method for determining cancer susceptibility
12/16/2004CA2528053A1 Phl p 5a derivatives having reduced allergenicity and retained t-cell reactivity
12/16/2004CA2528046A1 Flavivirus replicon packaging system
12/16/2004CA2527914A1 Improved secretion of neublastin
12/16/2004CA2527726A1 De-immunized anti-cd3 antibody
12/16/2004CA2527721A1 Chimeric adenovirus capsid proteins
12/16/2004CA2527346A1 Cell surface expression vector of sars virus antigen and microorganisms transformed thereby
12/16/2004CA2527044A1 Safe production of a product of interest in hybrid seeds
12/16/2004CA2526482A1 Peptide ligands of dendritic cells for nucleic acid vector targeting
12/16/2004CA2526365A1 Methods and compositions for amino acid production
12/16/2004CA2525401A1 Cell specific replication-competent viral vectors comprising a self processing peptide cleavage site