Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
06/2005
06/16/2005US20050131215 Nucleotide sequences coding ribosomal polypeptides for use as tool in detection of modulator for treatment of bacterial infection; bactericides; microbiocides
06/16/2005US20050131214 Cytokine polypeptide for use as tool in tissue repair
06/16/2005US20050131209 Crystallized hnf4 gamma ligand binding domain polypeptide and screening methods employing same
06/16/2005US20050131200 Biocompatability; polyphosphoester/polyphosphoramidate linkages; improved gene delivery into muscles; DNA vaccines
06/16/2005US20050130928 Modulating mammalian midkine activity; alters pulmonary vasculature development and smooth muscle cell development
06/16/2005US20050130927 For treating neoplasm, hypoproliferation, hyperproliferation, degenerative and neurodegenerative diseases, ischaemia, immune system disorder, infectious disease, or metabolic dysfunction
06/16/2005US20050130924 Reducing amounts of a selected wild-type mRNA target within a cell, by binding to the mRNA target an antisense compound; treating or preventing a disease or condition associated with a preselected target cellular protein in an animal
06/16/2005US20050130923 4'-thionucleosides and oligomeric compounds
06/16/2005US20050130919 Allow for inhibition of the expression of target alleles in a spatially and temporally regulatable manner; useful for investigating gene functions; genetic engineering
06/16/2005US20050130917 Preventing the attachment of Neisserial cells to epithelial cells (nasopharynx tract); antibodies, mutant proteins and nucleic acid from the adhesion-specific genes
06/16/2005US20050130916 Nucleic acid coding for the cgl1 polypeptide and diagnostic and therapeutic application of said nucleic acid and of the cgl1 polypeptide
06/16/2005US20050130911 Nucleic acid-lipophilic conjugates
06/16/2005US20050130889 Analog further comprises an amino acid substitution wherein the cysteine residue at BPI amino acid position 132 is replaced by another amino acid; for treating gram-negative bacterial infections in a subject; bactericidal for gram-positive bacteria and mycoplasma; enhances effectiveness of antibiotics
06/16/2005US20050130885 Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
06/16/2005US20050130881 Single amino acid based compounds for counteracting effects of reactive oxygen species and free radicals
06/16/2005US20050130320 Using antibody imaging to determine concentration and distribution of proteins in cells and tissues; immunoaffinity chromatography
06/16/2005US20050130308 Cloning and/or sequencing vector
06/16/2005US20050130307 Replication control region having the ability to convey a phenotype of altered plasmid copy number to the plasmid on which it resides
06/16/2005US20050130306 Conditionally replication-competent viral vector for use as gene transfer tool in genetic engineering
06/16/2005US20050130305 Use of a modified phosphate for enhancing the natural mutation rate in bacteria and mutating recombinant DNA phage inserts
06/16/2005US20050130304 Regulation of endogenous gene expression in cells using zinc finger proteins
06/16/2005US20050130289 Fast method of transforming competent cells
06/16/2005US20050130286 For diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders
06/16/2005US20050130284 Diacylglycerol acyltransferase genes, proteins, and uses thereof
06/16/2005US20050130280 Fructose-bisphosphate aldolase regulatory sequences for gene expression in oleaginous yeast
06/16/2005US20050130276 Modified isopropylmalate isomerase for use in production of leucine; medicine, cosmetics and enhancing animal feeds
06/16/2005US20050130271 Method of suppressing differentiation by administering a human serrate-1 polypeptide
06/16/2005US20050130269 Membrane protein fusion for use as diagnostic tool in genetic engineering; reporter gene expression
06/16/2005US20050130268 Recombinant DNA formed by ligating; gene expression; suppressing proliferation; medicine/drugs; host cell
06/16/2005US20050130267 Modulation of gene expression using localization domains
06/16/2005US20050130266 Prosuction of antibodies or (functionalized) fragments thereof derived from heavy chain immounogobulins of camelidae
06/16/2005US20050130265 Aiolos, Helios, Daedalos and Ikaros: genes, polypeptides, regulatory elements and uses thereof
06/16/2005US20050130264 Nucleotide sequences which code for the rpoB gene
06/16/2005US20050130262 Mutated photoproteins and their uses
06/16/2005US20050130259 Expression vector comprising nucleotide sequences coding peptidylprolyl isomerase for use as tool to improve heterologous gene expression
06/16/2005US20050130255 Process control based on microbiological activity
06/16/2005US20050130242 Uses of aldose-1-epimerase (mutarotase) for diagnosis and therapy of inflammatory diseases and sepsis
06/16/2005US20050130219 Using host transduced cells as bioreactor for expression and isolation of preferential gene products
06/16/2005US20050130218 Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
06/16/2005US20050130216 For use in detecting the presence of a target nucleic acid sequence in a sample
06/16/2005US20050130215 Using weighted color ratio to accurately determine gene expression patterns; bioinformatics
06/16/2005US20050130209 Expression vector comprising nucleotide sequences coding deoxyribonuclease for use as tool in treatment and prevention of cystic fibrosis
06/16/2005US20050130205 Replicating and propagating preferential nucleotide sequences using plasmid comprising restriction enzyme sites which generate hapaxoterministic ends; gene expression analysis
06/16/2005US20050130203 Novel GABAB receptor DNA sequences
06/16/2005US20050130202 Using presence of microsatellite sequences in mitochondrial polymerase g (POLG) gene as tool in detection and treatment of reproductive disorders
06/16/2005US20050130196 Using column chromatography to isolate preferential polynucleotides from solution; electrospray mass spectrometry
06/16/2005US20050130195 Functional molecule and process for producing the same
06/16/2005US20050130191 forming multibranched polyamide amine dendrimer molecules on walls of a U-shaped flow channel through which a solution containing target DNA is flowed;binding probe DNA to tips of said multibranched polyamide amine dendrimer molecules; andextracting said target DNA by hybridization with probes
06/16/2005US20050130184 Expression vector comprising coded looped RNA sequences for use in the prevention and treatment nervous system disorders; RNA interference
06/16/2005US20050130181 RNA interference mediated inhibition of wingless gene expression using short interfering nucleic acid (siNA)
06/16/2005US20050130179 Charge tags and the separation of nucleic acid molecules
06/16/2005US20050130178 Thermal cycling protocol for nucleic acid amplification uses two primers with different thermal melting temperatures; polymerase chain reaction (PCR)
06/16/2005US20050130177 Variable valve apparatus and methods
06/16/2005US20050130176 Molecular beacon comprising an oligonucleotide stem-loop structure and having a photoluminescent dye for use in determining the presence of a selected genetic sequence in a population
06/16/2005US20050130173 Methods of amplifying and sequencing nucleic acids
06/16/2005US20050130164 Generating test strip and/or microarrays comprised of immobilized DNA for use diagnostic tool in gene expression analysis
06/16/2005US20050130163 Surface-enhanced resonance Raman scattering (SERRS) active polymer beads; for use in detecting targect molecules
06/16/2005US20050130161 Identifying gene regulatory elements using methyltransferase and restriction enzyme disgestion; animal toxicity profiles; drug screening
06/16/2005US20050130160 Over-expression of extremozyme genes in pseudomonads and closely related bacteria
06/16/2005US20050130158 Screening method
06/16/2005US20050130156 Methods for making polynucleotides and purifying double-stranded polynucleotides
06/16/2005US20050130153 Plasmid targeting vector comprising fluorescent protein for use visualization tool in confocal microscopy; automated cell sorting
06/16/2005US20050130150 Using allelic variation in growth hormone as tool in diagnosis and treatment of growth hormone irregularities
06/16/2005US20050130147 Methods of preparing a targeting vector and uses thereof
06/16/2005US20050130146 Histone deactylase for use in identifying modulators for prevention and treatment of cell proliferative disorders
06/16/2005US20050130145 polynucleotides which identify and encode human secreted proteins (SECP); expression vectors, host cells, antibodies, and agonists; drug screening
06/16/2005US20050130143 Human smooth muscle myosin heavy chain polypeptide (hSMMyHC 7polypeptide) for use as tool in identifying modulator for prevention and treatment of hypertension, hypotension, heart and respiratory disorders
06/16/2005US20050130142 Forming double-stranded polynucleotide molecules
06/16/2005US20050130141 Process for preparing variant polynucleotides
06/16/2005US20050130140 Using site directed mutagenesis and polymerase chain reaction replication to produce polypeptides of preferential characteristics; directed protein evolution
06/16/2005US20050130137 Vitronectin adhesion receptor for use in identifying modulators for treatment and prevention of cell proliferative and blood disorders
06/16/2005US20050130135 Hepatitis a virus nucleotide sequences, recombinant proteins and uses thereof
06/16/2005US20050130131 Contacting macrophages in vitro with composition comprising hepatitis c viral particles, culture cells, incubate with non-macrophage cells, culture, recover viral particles; viricides and rational drug design
06/16/2005US20050130130 Killer cell activatory receptor ligand for use in diagnosis, prevention and treatment of infection, cell proliferative, autoimmune and arthritic disorders
06/16/2005US20050130129 Targeting gene transfer vectors to certain cell types by pseudotyping with viral glycoprotein
06/16/2005US20050130127 Coronavirus-like particles comprising functionally deleted genomes
06/16/2005US20050130124 Helper phage comprising conditional mutation in filamentous viral coat protein for use as tool in expression of heterologous gene products
06/16/2005US20050130123 Methods of examining (-) strand rna virus vectors having lowered ability to form grains and method of constructing the same
06/16/2005US20050130117 Using serine/threonine kinase screening tool in detection of modulator for prevention and treatment of inflammatory, respiratory, allergic and autoimmune diseases
06/16/2005US20050130116 Test system comprising cells expressing polymorphic cytochrome p450 for use as drug and toxicological screening tools; bioassay; rational drug design
06/16/2005US20050129717 Novel uses
06/16/2005US20050129713 For use in vaccine
06/16/2005US20050129705 hepatitis C virus; for activating cytotoxic t lymphocytes in presence of major histomcompatibility complex
06/16/2005US20050129704 An immunogenic complex that includes plant cells transformed with a chimeric gene containing a nucleotide sequence adapted for protein expression in plants and an RSV coding sequence that encodes an antigenic protein of RSV
06/16/2005US20050129702 Tick chitinase
06/16/2005US20050129701 Antibody to latent membrane proteins and uses thereof
06/16/2005US20050129698 Polypeptides (MBP1) capable of interacting with oncogenic mutants of the p53 protein
06/16/2005US20050129694 At least one (SEK) kinase inhibitor that acts in an synergistic manner to those inhibiting the virus multiplication for the Raf/MEK/ERK signal transmission path; influenza viricides
06/16/2005US20050129688 Monkey monoclonal antibodies specific to human B7.1 and/or B7.2 primatized forms thereof, pharmaceutical compositions containing, and use thereof as immunosuppressants
06/16/2005US20050129683 Human testis expressed patched like protein
06/16/2005US20050129679 By use of antagonists to JAM-1 Claudin-4 and occludin; drug delivery
06/16/2005US20050129673 Chondrocyte cell-lines
06/16/2005US20050129672 For isolating an enriched or purified population of motor neurons from a mixed population of human brain and/or spinal cells; for therapeutically targeting motor neurons eg myeloradiculopathy
06/16/2005US20050129670 Tumor cells modified to express B7-2 with increased immunogenicity and uses therefor
06/16/2005US20050129669 Gene therapy; comprising a targeting sequence, a regulatory sequence, an exon and an unpaired splice-donor site
06/16/2005US20050129665 Isolated lineage negative hematopoietic stem cells and methods of treatment therewith
06/16/2005US20050129661 For gene therapy; cochleates containing rep proteins and DNA with inverted terminal repeats (ITRs) for use as a vector for efficient delivery of genes
06/16/2005US20050129660 For gene therapy by transfection; forming an occlusion of fluid flow in a limb; inserting a viral vector into the lumen of a vein or artery in said limb, thereby forcing fluid into the extravascular space, releasing the occlusion
06/16/2005US20050129657 Interferon-alpha induced gene
06/16/2005US20050128863 Device for fast vibration of tubes containing samples