Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
06/2005
06/30/2005US20050142635 chimeric antibodies comprising variable domain peptides, DNA codes for the antibodies, expression vectors, host cells and a process of culturing the host cells to produce the monoclonal antibodies, used for immunotherapy; nonimmunogenic
06/30/2005US20050142634 Novel modulator of non-genomic activity of nuclear receptors (mnar) and uses thereof
06/30/2005US20050142633 producing proteins having with hydrolase enzyme activity from proenzymes, derived from host cells comprising methylotrophic yeast; proteolytic enzymes
06/30/2005US20050142632 mixture of components from collagenases and components from proteases from clostridium, used for improving the isolation results with respect to yield, viability and integrity of the cells
06/30/2005US20050142628 Use
06/30/2005US20050142625 monoclonal antibodies or antigen-binding fragments having specific binding affinity to an epitope of protein kinases polypeptides, used for the diagnosis and treatment of various kinase-related diseases in humans
06/30/2005US20050142617 gene related to bone density; possible use in the drug screening, treatment, and diagnosis of bone disorders such as osteoporosis
06/30/2005US20050142607 Contacting biological sample with at least two antibodies wherein epitope in Moraxella catarrhalis for each antibody is either internal or surface exposed and detecting binding of antibodies to sample, wherein binding is indicative of presence of Moraxella catarrhalis; bacteria-induced acute otitis media
06/30/2005US20050142604 Methods and compositions to treat cardiovascular disease using 1419, 58765 and 2210
06/30/2005US20050142603 Method for producing a protein by culturing in culture medium a host cell transfected with a vector comprising a nucleic acid having the given nucleotide sequence; treatment of myocardial necrosis or ischemia reperfusion injuries; gene therapy; inhibits cell death associated with hypoxia, apoptosis
06/30/2005US20050142601 Nucleic acids encoding an enediyne polyketide synthase complex
06/30/2005US20050142598 Oligonucleotides containing molecular rods
06/30/2005US20050142588 Nucleotide sequences coding sodium/bile co-transport protein for use in diagnosis, prevention and treatment of cell proliferative; pharmacogenomics
06/30/2005US20050142583 Using immobilized oligonucleotides as tools in synthesis, selection, amplification and evolution of non-natural molecules based on nucleic acid templates
06/30/2005US20050142582 Aptamers and methods for their in vitro selection and uses thereof
06/30/2005US20050142581 Methods for selecting a target molecule that has an affinity for a ligand that is equal to or greater than a baseline affinity wherein either one or both of the target molecule and ligand, independently, is a microRNA; mass spectrometry methods for detecting binding interactions of ligands to substrates
06/30/2005US20050142578 Introducing library of siNA constructs into a biological system; determining nucleotide sequence of a siNA construct in which a process has been modulated; cellular proliferation, differentiation, morphology, angiogenesis, migration, viral multiplication; gene expression and engineering; transcription
06/30/2005US20050142575 Detection and identification of staphylococcus aureus using the 16S-23S rRNA spacer
06/30/2005US20050142571 Methods for nucleic acid isolation and kits using solid phase material
06/30/2005US20050142570 Methods for nucleic acid isolation and kits using a microfluidic device and sedimenting reagent
06/30/2005US20050142566 Sperm-specific cation channel, catSper2, and uses therefor
06/30/2005US20050142565 Extraction of DNA or RNA from cells; microfluidic device with silicon substrate; inlet for blood, buffered saline solution, lysing agent, alcohol and/or air; mixer; lysing chamber for lysis of cellular membranes; binding chamber; flow control valve; plasma etching silica surface
06/30/2005US20050142561 Intracellular signaling pathways in diabetic subjects
06/30/2005US20050142553 Serine hydroxymethyltransferase as a target for herbicides
06/30/2005US20050142552 Susceptibility locus for schizophrenia
06/30/2005US20050142550 Increased copy number of a nucleic acid linked to a reporter nucleic acid; screen cells for increased expression of a polypeptide derived from the nucleic acid, and related cell
06/30/2005US20050142549 Reading, detection or quantification method, hybrids or complexes used in said method and the biochip using same
06/30/2005US20050142548 Allelic variants of grp50
06/30/2005US20050142546 Assays for identifying modulators of rhomboid polypeptides
06/30/2005US20050142545 Methods for identifying small molecules that bind specific rna structural motifs
06/30/2005US20050142543 Method of designing addressable array for detection of nucleic acid sequence differences using ligase detection reaction
06/30/2005US20050142535 Ogligonucleotides comprising alternating segments and uses thereof
06/30/2005US20050142183 Expressing by means of a eukaryotic or prokaryotic vector, in which a nucleic acid coding for the mistletoe lectin polypeptide according to the usual genetic code or the fragment thereof is cloned in a suitable heterologous eukaryotic or prokaryotic host
06/30/2005US20050142182 Long circulating liposome
06/30/2005US20050142179 Transfection reagents
06/30/2005US20050142151 Live attenuated vaccines against brucellosis and infection by other diseases; trans complementation of the Brucella wboA gene is used to maintain an expression vector in an attenuated Brucella host cell in a vaccinee; heterologous antigens can be expressed using this Brucella platform
06/30/2005US20050142149 Virulence genes and proteins, and their use
06/30/2005US20050142148 e.g. include antigenic gene product of another virus, such as influenza virus, respiratory syncytial virus, human metapneumovirus and avian pneumovirus; respiratory tract infections
06/30/2005US20050142146 Vaccine; against Chlamydia pneumonia; therapy, prevention of infections,
06/30/2005US20050142145 Derivatives of choline binding proteins for vaccines
06/30/2005US20050142144 Epitope sequences
06/30/2005US20050142138 Endothelial cell expression patterns
06/30/2005US20050142136 Anti-interleukin 8 therapy for tumor osteolysis
06/30/2005US20050142132 Prevention and treatment of amyloidogenic disease
06/30/2005US20050142127 Provides novel peptides and proteins that effect protein phosphorylation and nucleic acid molecules encoding such peptide and protein molecules, all of which are useful in the development of human therapeutics and diagnostic compositions and methods
06/30/2005US20050142120 Cells expressing anti-Fc receptor binding components
06/30/2005US20050142115 Papilloma pseudovirus and preparation
06/30/2005US20050142114 Preferentially targeting liposome to mammalian immune cell such as myeloid progenitor cell, monocyte, dendritic cell, macrophage or T-lymphocyte by administering to cell a liposome comprising an active agent and an outer surface that comprises a targeting ligand that binds marker on surface of cell
06/30/2005US20050142111 Prevention of transplant arteriosclerosis and interstitial fibrosis by stable and long-term expression of heme oxygenase-1 in grafts
06/30/2005US20050142098 Polyoxyethylene glycol conjugated neublastin polypeptide dimers; exhibit prolonged bioavailability
06/30/2005US20050142064 Administering test drug infected with adenovirus used as a vector and engineered by incorporating a detectable reporter gene and having human PXR binding regions falling within an untranslated region of a human CY3A gene; genetic engineering and expression; gene therapy; drug screening
06/30/2005DE10355409A1 Sphärische, magnetische Silicagel-Träger mit vergrößerter Oberfläche für die Aufreinigung von Nukleinsäuren Spherical magnetic silica gel carrier with increased surface area for purification of nucleic acids
06/30/2005DE10347888A1 Verfahren zur Herstellung von enantiomerenangereicherten alpha-Hydroxycarbonsäuren bzw. -amide A process for the preparation of enantiomerically enriched alpha-hydroxycarboxylic acids and amides
06/30/2005DE10345386A1 Recombinant yeast cells, useful for detecting estrogenic compounds in the environment, contain a plasmid with an estrogen-receptor gene and a plasmid with a reporter gene controlled by promoter with an estrogen response element
06/30/2005CA2588965A1 Novel chimeric plasminogen activators and their pharmaceutical use
06/30/2005CA2560045A1 Methods and compositions comprising bacteriophage nanoparticles
06/30/2005CA2550507A1 Method for producing yellow flower by controlling flavonoid synthetic pathway
06/30/2005CA2550192A1 Nucleic acid probes and broad-range primers from regions in dna directed rna polymerase subunit b genes, and methods in which they are used
06/30/2005CA2550058A1 Pharmaceutical composition comprising a tgf-beta2 antisense oligonucleotide and a chemotherapeutic
06/30/2005CA2550056A1 Plants having modified yield, and method for making the same comprising increased expression of a growth related ubx (grubx) protein
06/30/2005CA2550028A1 Transgenic plants with reduced level of saturated fatty acid and methods for making them
06/30/2005CA2550013A1 Bactericide against streptococcus mutans and streptococcus sobrinus
06/30/2005CA2549936A1 Dominant gene suppression transgenes and methods of using same
06/30/2005CA2549884A1 Cytokine binding domains
06/30/2005CA2549878A1 Glycosylation-deficient hepatocyte growth factor
06/30/2005CA2549852A1 Method and nucleic acids for the improved treatment of breast cell proliferative disorders
06/30/2005CA2549573A1 Dna sequence, and recombinant preparation of group 4 major allergens from cereals
06/30/2005CA2549529A1 Helical synthetic peptides that stimulate cellular cholesterol efflux
06/30/2005CA2549523A1 Cytochrome c protein and assay
06/30/2005CA2549386A1 Methods for synthesis of encoded libraries
06/30/2005CA2549303A1 Novel sodium channel
06/30/2005CA2549171A1 Psod expression units
06/30/2005CA2549097A1 Method of producing arachidonic acid-containing plants
06/30/2005CA2549031A1 Method for obtaining an enriched population of sirna-expressing cells
06/30/2005CA2549000A1 Method for treating neurological disorders
06/30/2005CA2548972A1 Treatment of mammals by sirna delivery into mammalian nerve cells
06/30/2005CA2548769A1 Ztnf 12, a tumor necrosis factor
06/30/2005CA2548349A1 P ef-tu expression units
06/30/2005CA2548347A1 Methods for generating immunity to antigen
06/30/2005CA2548338A1 Ip-10 antibodies and their uses
06/30/2005CA2548306A1 Pgro expression units
06/30/2005CA2548125A1 Methods for the preparation of a fine chemical by fermentation
06/30/2005CA2548100A1 Methods and compositions for treatment of interferon-resistant tumors
06/30/2005CA2547860A1 Methods for the preparation of lysine by fermentation of corynebacterium glutamicum
06/30/2005CA2547792A1 Gene variants coding for proteins from the metabolic pathway of fine chemicals
06/30/2005CA2547765A1 Yeast strains with improved fructose fermentation capacity
06/30/2005CA2547635A1 A human cytotoxic t-lymphocyte epitope and its agonist epitope from the non-variable number of tandem repeat sequence of muc-1
06/30/2005CA2547563A1 Corn plant mon88017 and compositions and methods for detection thereof
06/30/2005CA2545675A1 Rnai potency prediction method
06/30/2005CA2545671A1 Brachyspira pilosicoli 72kda outer-membrane protein and diagnostic and therapeutic uses thereof
06/30/2005CA2545006A1 Biosensors for detecting macromolecules and other analytes
06/29/2005EP1548481A1 Cofocal microscope, fluorescence measuring method and polarized light measuring metod using cofocal microscope
06/29/2005EP1548441A1 Method for transfer of a substance
06/29/2005EP1548438A1 Interaction detecting method and bioassay device, and bioassay-use substrate
06/29/2005EP1548423A1 Image processing method for biochemical test
06/29/2005EP1548132A1 Nucleic acid labeling method by PCR
06/29/2005EP1548130A1 Fen endonucleases
06/29/2005EP1548129A1 Method of diagnosing integration dysfunction syndrome using blood
06/29/2005EP1548128A1 Method of recovering dna
06/29/2005EP1548127A1 PRIMER AND PROBE FOR DETECTING i VIBRIO VULNIFICUS /i AND DETECTION METHOD USING THE SAME