Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
06/2003
06/18/2003EP1319013A2 Linker phosphoramidites for oligonucleotide synthesis
06/18/2003EP1319012A1 Process for producing multiple oligonucleotides on a solid support
06/18/2003EP1318796A2 Polynucleotide intercalator interceptors and inhibitors
06/18/2003CN1425065A Method of controlling telomere length
06/18/2003CN1424325A Production of reorganized human parathyroid hormone 1-34 peptide
06/17/2003US6579972 An antibody having a specific binding affinity to a polypeptide of given amino acid sequence; can use in treating diabetes, skeletal muscle diseases, Alzheimer's disease, or peripheral neuropathies with an agonist or antagonist
06/17/2003US6579856 Inhibition of stress activated protein kinase (SAPK) pathway and sensitization of cells to cancer therapies
06/17/2003US6579710 Human kinases and polynucleotides encoding the same
06/17/2003US6579683 A ligand which is a member of Ephrin family of Eph family receptor interactive protein has been shown to be expressed by arterial endothelial cells but not by venous endothelial cell, useful for distinguishing target artieris and veins
06/17/2003US6579680 Detecting genetic polymorphisms; provide probes, hybridize probes, detect hybridization of probes
06/17/2003US6579520 IL-17 related mammalian cytokine polypeptides (IL-17E)
06/17/2003CA2241331C Reusable solid support for oligonucleotide synthesis, process for production thereof and process for use thereof
06/17/2003CA2124928C Hbv amplifier probes for use in solution phase sandwich hybridization assays
06/13/2003WO2003047602A1 Immunostimulatory oligodeoxynucleotides
06/13/2003CA2452909A1 Immunostimulatory oligodeoxynucleotides
06/12/2003WO2003048723A2 Label-free detection of nucleic acids via surface plasmon resonance
06/12/2003WO2003048395A1 Methods for the selection and cloning of nucleic acid molecules free of unwanted nucleotide sequence alterations
06/12/2003WO2003048387A2 Labelled nucleotides
06/12/2003WO2003048345A1 Phenotypic screen of chimeric proteins
06/12/2003WO2003048338A2 Nucleic acid injected into hepatic vein lumen and delivered to primate liver
06/12/2003WO2003048332A2 METHODS FOR ANALYZING METHYLATED CpG ISLANDS AND GC RICH REGIONS
06/12/2003WO2003048325A2 Nucleotide sequences of shrimp beta-actin and actin promoters and their use in genetic transformation technology
06/12/2003WO2003048315A2 Antisense modulation of mdm2 expression
06/12/2003WO2003048304A2 ALLOIOCOCCUS OTITIDIS OPEN READING FRAMES (ORFs) ENCODING POLYPEPTIDE ANTIGENS, IMMUNOGENIC COMPOSITIONS AND USES THEREOF
06/12/2003WO2003048303A2 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
06/12/2003WO2003048187A2 Peptides and use thereof in therapeutic agents against hiv infection
06/12/2003WO2003048179A2 Thermolabile hydroxyl protecting groups and methods of use
06/12/2003WO2003047421A2 Methods and reagents for diagnosis and treatment of diabetes
06/12/2003WO2003020734A3 Labeled nucleoside polyphosphates
06/12/2003WO2003012070A3 Gene associated with bone disorders
06/12/2003WO2002103031A3 Methods for detecting and treating the early onset of aging-related conditions
06/12/2003US20030110521 Anxiolytic agents; psychological disorders; insertion of genetic vector into nucleic acids, transcription
06/12/2003US20030109677 TIE-2 ligands, methods of making and uses thereof
06/12/2003US20030109672 Secreted and transmembrane polypeptides and nucleic acids encoding the same
06/12/2003US20030109479 Bioactive substances useful for the delivery of effector units in animals. Also disclosed are methods for utilizing the bioactive substances of the invention.
06/12/2003US20030109471 Nucleic acid-based compounds and methods of use thereof
06/12/2003US20030109470 Variants thereof, are described wherein a nucleic acid sequence of the invention exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers such as those listed expression of a nucleic acid
06/12/2003US20030109438 Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
06/12/2003US20030109436 Wherein cysteine residue number 132 or 135 is replaced by another amino acid residue, preferably an alanine or serine residue and/or wherein the leucine residue at position 193 is the carboxy terminal residue. DNA sequence codes for cells
06/12/2003US20030109032 Oligonucleotide labeling reagents
06/12/2003US20030109003 Antitumor agent; transformation of expression vector; genetic engineering; process control hybrids
06/12/2003US20030108983 Secreted and transmembrane polypeptides and nucleic acids encoding the same
06/12/2003US20030108924 Isolated polynucleotide; determination genotype; analyzing
06/12/2003US20030108923 Blocking gene expression
06/12/2003US20030108907 Nucleic acids, proteins, and antibodies
06/12/2003US20030108899 Detection hybrids; masking biosynthesis; photosensitive blocking agents; determination accumulated fluorescence radiation
06/12/2003US20030108882 Nucleic acid encoding a retinoblastoma binding protein (RBP-7) and polymorphic markers associated with said nucleic acid
06/12/2003US20030108873 Systems for the detection of target sequences
06/12/2003CA2473883A1 Alloiococcus otitidis open reading frames (orfs) encoding polypeptide antigens, immunogenic compositions and uses thereof
06/12/2003CA2469477A1 Phenotypic screen of chimeric proteins
06/12/2003CA2469066A1 Labelled nucleotides
06/12/2003CA2468991A1 Methods and reagents for diagnosis and treatment of diabetes
06/12/2003CA2464897A1 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
06/11/2003EP1318401A2 Method for the early detection of the seroconversion of an anti hepatitis C virus antibody
06/11/2003EP1317553A2 Pdes and uses thereof
06/11/2003EP1317528A2 Lipoxygenase
06/11/2003EP1317466A2 Synthons for oligonucleotide synthesis
06/11/2003EP1317464A2 Fluorescent nucleobase conjugates having anionic linkers
06/11/2003EP0694075B1 Thermostable dna topoisomerase v
06/11/2003EP0690873B1 Growth differentiation factor-8
06/11/2003EP0662086B1 Protein l and hybrid proteins thereof
06/11/2003EP0644900B1 A monoclonal antibody to a human mdr1 multidrug resistance gene product, and its use
06/11/2003CN1422953A Gene sequence of Japanese shistosome China mainland strain gynecophoric canal protein
06/11/2003CN1422952A Human interferon alpha 2b gene cDNA code modification recombination sequence
06/10/2003US6576783 Oligonucleotide protecting groups
06/10/2003US6576752 Aminooxy functionalized oligomers
06/10/2003US6576744 Cytokine receptor zalpha11
06/10/2003US6576475 Assay system and novel labelled compounds for use therewith
06/10/2003US6576453 Thermostable DNA ligase mutants
06/10/2003US6576448 Isolating preferential nucleotide sequences; obtain sample of nucleotide sequences, incubate with restriction enzymes, tie adaptors, methylate, denature, methylated incubate with preferential enzymes, elongate, recover sequence
06/10/2003US6576434 Transport protein of given amino acid sequence; exposing cells that express the protein to compound; measuring ion transport; use in treatment of interleukin mediated atopic allergy, asthma and cystic fibrosis
06/10/2003US6576426 Tag reagent and assay method
06/10/2003US6576424 Solid support for use in the determination, classification and mapping of biopolymer sequences
06/10/2003US6576218 Transplacental delivery of oligonucleotides
06/10/2003CA2191795C Antisense oligonucleotide modulation of raf gene expression
06/05/2003WO2003046581A2 Methods for diagnosis and treatment of epithelial-derived cancers,such as colorectal cancers and kidney cancers
06/05/2003WO2003046221A1 Method for the specific identification of orthopoxvirus with the aid of a miniature biological chip.
06/05/2003WO2003046155A1 Ϝ-glutamylcysteine-producing yeast
06/05/2003WO2003046146A2 Compositions and methods of selective nucleic acid isolation
06/05/2003WO2003046134A2 Expression of polypeptides in rod outer segment membranes
06/05/2003WO2003046133A2 Regulatory nucleic acid assay for diagnostic and library screens
06/05/2003WO2003045969A1 Coupling reagent for h-phosphonate chemistry
06/05/2003WO2003045310A2 Digital assay
06/05/2003WO2002088396A9 Reagents and methods for automated in situ or microarray hybridization
06/05/2003WO2002077261A3 Human potassium channel
06/05/2003WO2002060932A3 A serpin in bifidobacteria
06/05/2003US20030106097 Hydrolases; insect/disease resistant plants; controlling cellulose concentration during cell wall deposition
06/05/2003US20030106093 Coleoptera resistant plants; biological pest control
06/05/2003US20030105311 Oligonucleotides having A-DNA form and B-DNA form conformational geometry
06/05/2003US20030105309 Novel bicyclonucleoside and oligonucleotide analogue
06/05/2003US20030105308 Polymerases; gene expression inhibition; gene therapy
06/05/2003US20030105303 Primate phagocytic leukocyte protein; detection and diagnosis of immunological disorders; cancer detection
06/05/2003US20030105293 Human circulating cytokine cc-1
06/05/2003US20030105288 Membrane proteins; antitumor agents; antiproliferative agents; tumor necrosis factor
06/05/2003US20030105286 Comprises pseudo-isocytosine and pseudo-uracil for increasing binding affinity to DNA/RNA strands
06/05/2003US20030105284 Small and intermediate conductance, calcium-activated potassium channels and uses thereof
06/05/2003US20030105056 Used to produce amino- modified linkers that space an oligonucleotide from a solid support
06/05/2003US20030105051 Nucleic acid treatment of diseases or conditions related to levels of HER2
06/05/2003US20030105035 Administering synthetic, oligonucleotide, antibody that binds to epidermal growth factor receptor or a cytotoxic agent selected from taxanes, platinum-derived agents, and topoisomeraseII-selective drugs for inhibiting proliferation
06/05/2003US20030105013 For therapy of wounds, various cancers, and disorders of the vessels including atherosclerosis and cardiac hypertrophy