Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
08/2003
08/07/2003CA2474485A1 Light activated gene transduction using ultraviolet light for cell targeted gene delivery
08/07/2003CA2474468A1 Amplifying repetitive nucleic acid sequences
08/07/2003CA2474414A1 Oligonucleotides comprising alternating segments and uses thereof
08/07/2003CA2474091A1 Method of fixing biomolecule to carrier
08/07/2003CA2474006A1 Variants of the alpha 1 subunit of human ampk
08/06/2003EP1333093A2 Human muscle nad: arginine adpribosyltransferase
08/06/2003EP1333035A2 Growth differentiation factor-8
08/06/2003EP1017705B1 Rapid rna isolation procedure
08/06/2003EP0985052B1 Methods and compositions to identify swine genetically resistant to f18 e. coli associated diseases
08/06/2003EP0788557A4 Rapid detection and identification of nucleic acid variants and pathogens
08/06/2003EP0695305B1 Method of forming oligonucleotides
08/06/2003CN1434921A T2R taste receptors and genes encoding same
08/06/2003CN1434723A Immunostimulatory oligodeoxynucleotides
08/06/2003CN1434054A Dowble-stranded RNA and use thereof
08/06/2003CN1117098C Cancer suppressing action of antisense nucleic acid to leukemia gene of bursa-dependent lymphocyte
08/06/2003CN1117097C Cancer suppressor action of antisense nucteic acid of para-insulin growth factor receptor gene
08/05/2003US6602984 Human elastase IV
08/05/2003US6602858 Ribozyme for use as tool in genetic engineering
08/05/2003US6602713 Antisense modulation of protein phosphatase 2 catalytic subunit beta expression
08/05/2003US6602688 Transforming a thioredoxin reductase-deficient Escherichia strain with a nucleotide molecule encoding antibody; culturing; enzyme cleaves nontoxic prodrug to give the toxic drug; antitumor agent
08/05/2003US6602684 Culturing a host cell to express a nucleic acid encoding beta (1,4)-N- acetylglucosaminyltransferase III under conditions for production of a polypeptide; can use to provide proteins with improved therapeutic properties
08/05/2003US6602668 For enhancing an amplification protocol
07/2003
07/31/2003WO2003062783A2 Light addressable electrochemical detection of duplex structures
07/31/2003WO2003062452A2 Methods for the integrated synthesis and purification of oligonucleotides
07/31/2003WO2003062450A2 Probe correction for gene expression level detection
07/31/2003WO2003062447A2 Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression
07/31/2003WO2003062445A2 Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for pcr analysis
07/31/2003WO2003062422A1 Signalling aptamer complexes
07/31/2003WO2003062414A2 Methods of obtaining isoform specific expression in mammalian cells
07/31/2003WO2003062389A2 UNIVERSAL RT-COUPLED PCR METHOD FOR THE SPECIFIC AMPLIFICATION OF mRNA
07/31/2003WO2003062381A2 Multiply-substituted protease variants
07/31/2003WO2003062273A2 Modulator of the notch signalling pathway and use thereof in medical treatment
07/31/2003WO2003044178A3 Hybrid oligonucleotide primers for amplification of dna and uses thereof
07/31/2003WO2003041659A3 Method and identification of downstream mrna ligands to fmrp and their role in fragile x syndrome and associated disorders
07/31/2003WO2003031571A3 Novel human proteins, polynucleotides encoding them and methods of using the same
07/31/2003WO2003028636A3 Antisense modulation of il-1 receptor-associated kinase-4 expression
07/31/2003WO2003025140A3 Transductin-1 and transductin-2 and applications to hereditary deafness
07/31/2003WO2003014138A8 Method for immobilizing compounds by means of nitron formation and arrangement for immobilizing compounds
07/31/2003WO2002090377A3 Peptides that bind to dna and inhibit dna replication, and methods of use
07/31/2003WO2002090372A3 Products containing charged biomaterials and method for the preparation thereof
07/31/2003WO2002083849A9 Vascular endothelial growth factor 2
07/31/2003WO2002024909A3 Receptor nucleic acids and polypeptides
07/31/2003WO2002024056A3 METHODS AND COMPOSITIONS FOR DETECTING CANCERS ASSOCIATED WITH METHYLATION OF hMLH1PROMOTER DNA
07/31/2003WO2002020847A3 Gene and sequence variation associated with lipid disorder
07/31/2003WO2002004489A3 Polymorphic kinase anchor proteins and nucleic acids encoding the same
07/31/2003US20030144499 Photocleavable protecting groups and methods for their use
07/31/2003US20030144497 Novel human transferase proteins and polynucleotides encoding the same
07/31/2003US20030144489 Hybrids; genetic engineered libraries
07/31/2003US20030144233 Conformation-activity relationship of apoptosis-inducing phosphodiester oligonucleotides
07/31/2003US20030144231 Locked Nucleoside Analogues is a biochemical conjugate of nucleotides; as an aptamer in specific binding of antibiotics, drugs, amino acids, peptides, enzymes, saccharides, polysaccharides; heat resistance
07/31/2003US20030143735 Contacting human vpr interacting protein with a test compound and comparing the affinity of the vpr in the presence and absence of it
07/31/2003US20030143724 Prepatterned substrate for optical synthesis of DNA probes
07/31/2003US20030143708 Method and reagent for the treatment of alzheimer's disease
07/31/2003US20030143697 Nucleic acid encoding a fusion polypeptide that forms a multimer that binds to a cytokine to form a nonfunctional complex; cytokine antagonists for the treatment of cytokine-related diseases or disorders
07/31/2003US20030143676 Receptor polypeptides and polynucleotides encoding such polypeptides; for treating a disorder characterized by an elevated level of osteopontin
07/31/2003US20030143674 Polypeptides fused to heterologous polypeptide sequences, and an antibodies which bind to the above polypeptides
07/31/2003US20030143616 Addressable protein arrays
07/31/2003US20030143607 Combining a sample suspected of containing target nucleic acid with a probe comprising a nucleic acid and a tag with a phosphramidite group to hybridize to target nucleic acid, detecting presence of probe
07/31/2003US20030143605 Methods for the selection and cloning of nucleic acid molecules free of unwanted nucleotide sequence alterations
07/31/2003US20030143599 Attaching a primer; ligation of an adaptor sequence or homopolymeric tailing with terminal deoxynucleotidyltransferase
07/31/2003US20030143598 Bioconjugate-nanoparticle probes
07/31/2003US20030143591 Measuring change in fluorescence upon hybridization
07/31/2003US20030143581 Target analyte supported on conductive support containing a nanoparticle comprising a photoelectrochemically active group, exposing the active group with light to generate photoelectric current, measuring the current
07/31/2003US20030143579 Inhibitors of apoptosis
07/31/2003US20030143570 A solid support comprising immobilized latent thiol groups, activating the thiol groups and reacting activated thiol groups with an affinity ligand having atleast an alpha-beta unsaturated carbonyl group, immobizing ligand on the support
07/31/2003US20030143569 Methods of immobilizing ligands on solid supports and apparatus and methods of use therefor
07/31/2003US20030143561 Nucleoside derivatives for library preparation
07/31/2003US20030143555 Method for labeling and fragmenting DNA
07/31/2003US20030143551 Reading multiple chemical arrays
07/31/2003US20030143543 Genetic changes in atypical nodular proliferations in congenital melanocytic nevi
07/31/2003US20030143538 Oligonucleotides are attached to nanoparticles and have sequences complementary to portions of a nucleic acid; hybridization causes a detectable change
07/31/2003US20030143535 Nucleic acid accessible hybridization sites
07/31/2003US20030143331 Contacting thiosphosphate mono- or oligonucleotide with a solid support functionalized with linker moiety bearing a functional group to permit linkage of mono- or oligonucleotide to solid support via thiophosphate sulfur atom
07/31/2003US20030143131 Device for chemical and biochemical reactions using photo-generated reagents
07/31/2003CA2473960A1 Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for pcr analysis
07/31/2003CA2473683A1 Signalling aptamer complexes
07/31/2003CA2472729A1 Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression
07/31/2003CA2472725A1 Multiply-substituted protease variants
07/30/2003EP1331011A2 Derivatized oligonucleotides having improved uptake and other properties
07/30/2003EP1330650A2 Method and apparatus for reading reporter labeled beads
07/30/2003EP1330553A1 A kit for detecting non-pathogenic or pathogenic influenza a subtype h5 virus
07/30/2003EP1330550A2 Atropisomers of asymmetric xanthene fluorescent dyes and methods of dna sequencing and fragment analysis
07/30/2003EP1086245B1 Multi-fluorescent hairpin energy transfer oligonucleotides
07/30/2003EP1054726B1 Apparatus for chemical and biochemical reactions using photo-generated reagents
07/30/2003CN1432578A Recombinant protein A gene and prepn and application of its expression product
07/30/2003CN1432577A Sheep growth hormone releasing hormone gene and its expression product and application
07/30/2003CN1432576A Nucleotide with specificity to o-antigen of type-12 shigella shigae and colibacillus 0152
07/29/2003US6600032 Compound for use in the treatment of viral, protozoan and parasitic infections
07/29/2003US6600031 Methods of making nucleic acid or oligonucleotide arrays
07/29/2003US6600028 Tricyclic base analogues
07/29/2003US6599880 Analog further comprises an amino acid substitution; for treating gram-negative bacterial infections in a subject
07/29/2003US6599741 Modulating transcription of genes in vascular cells
07/29/2003US6599728 Tankyrase II interacts with telomere-associated proteins, thereby affecting telomerase activity and potentially telomere length
07/29/2003US6599719 For therapy of rheumatoid arthritis, tumors
07/29/2003US6599716 Nucleic acids encoding NTR3, a member of the TNF-receptor supergene family
07/29/2003US6599700 Methods for detection of transition single-nucleotide polymorphisms
07/29/2003US6599698 Mutated steroid hormone receptors, methods for their use and molecular switch for gene therapy
07/29/2003CA2122044C Hiv immunotherapeutics
07/29/2003CA2093664C Modified ribozymes
07/24/2003WO2003060151A2 Novel calpastatin (cast) alleles