Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
08/2005
08/11/2005WO2005010145A3 Method and compositions for detection and enumeration of genetic variations
08/11/2005WO2004096016A3 Modulation of glucagon receptor expression
08/11/2005WO2004094463A3 Peptide inhibitors of autophosphorylation protein kinases
08/11/2005WO2004083394A3 Human g protein-coupled receptors and modulators thereof for the treatment of inflammatory disorders
08/11/2005WO2004079342A3 Use of nucleic acid mimics for internal reference and calibration in a flow cell microarray binding assay
08/11/2005WO2004043407A3 Methods and products for treating staphylococcal infections
08/11/2005WO2004039940A3 Polynucleotide encoding novel human g-protein coupled receptors, and splice variants thereof
08/11/2005WO2004036190A3 Compositions and methods for detecting west nile virus
08/11/2005WO2004033636A3 Protein modification and maintenance molecules
08/11/2005WO2003102159A3 Novel proteins and nucleic acids encoding same
08/11/2005US20050177898 Maize metallothionein 2 promoter and methods of use
08/11/2005US20050177897 Isolated nucleic acid molecule of a nucleotide sequence for promoters that initiate transcription
08/11/2005US20050176948 Libraries; locked nucleic acids; peptide nucleic acids
08/11/2005US20050176946 Constitutive promoter from Arabidopsis
08/11/2005US20050176945 Cloning and characterization of slc26a7 and slc26a9 anion exchangers
08/11/2005US20050176944 Intracellular signaling polypeptide for identifying modulator for prevention and treatment cell proliferative, endocrine, autoimmune/inflammatory, neurological, gastrointestinal, reproductive, developmental, and vesicle trafficking disorders
08/11/2005US20050176670 Recombinant DNA for gene suppression
08/11/2005US20050176665 RNA interference mediated inhibition of hairless (HR) gene expression using short interfering nucleic acid (siNA)
08/11/2005US20050176663 RNA interference mediated inhibition of protein tyrosine phosphatase type IVA (PRL3) gene expression using short interfering nucleic acid (siNA)
08/11/2005US20050176634 substitution or the elimination ofcysteine residue (Cys) in the C-terminal portion of the wild type protein polypeptide sequence; prevents multimerisation of monomeric form but does not affect dimerisation; storage stability; treatment of ischemia, scleroderma, skin ulcer, aging, burn, wound; cosmetic
08/11/2005US20050176125 Alternatively spliced isoform of CDC25A phosphatase and methods of use
08/11/2005US20050176110 Using immobilized xylose isomerase to isolate and recover biopolymers from industrial process streams and biotech off waste
08/11/2005US20050176106 Use of the RTX secretion system to achieve heterologous polypeptide secretion by Vibrio cholerae
08/11/2005US20050176104 Using overexpression of nucleotide sequences coding tumor associated antigen as diagnostic/prognostic tool in detection of cancer
08/11/2005US20050176101 Enzyme expression methods
08/11/2005US20050176099 Plasmid system for multigene expression
08/11/2005US20050176097 Bacterial bioreactor for propagation of enzymatic polypeptides
08/11/2005US20050176083 Blood protein fusion comprising serine-protease (SP) domain for use in treatment of thrombosis a nd blood coagulation disorders
08/11/2005US20050176065 Biarsenical molecules label tetracycsteine polypeptides; orthogonal labelling for observing conformational changes; solid phase synthesis; kits
08/11/2005US20050176047 Expression vector comprising regulatory sequences associated with tissue specific expression of ovomucoid gene for use as a gene expression control elements in heterologous gene transfer and transcription in birds
08/11/2005US20050176041 Using membrane proteins as tool in diagnosis, prevention and treatment of cell proliferative disorders
08/11/2005US20050176039 Macrophage migration inhibitory factor (MIF) as marker for urological inflammatory disease
08/11/2005US20050176038 Transcribed non-naturally occurring RNA sequences which form hairpin structures for use in treatment of cell proliferative disorders; gene therapy; antisense agents
08/11/2005US20050176035 Destabilization of hybridization via DNA N-glycosylase/uridine nucleosidase, insertion of probe; kits
08/11/2005US20050176024 chemically synthesized double stranded siNA that directs cleavage of EGFR such as HER1, HER2, HER3 or HER4; diagnosis or treatment of cancer for example
08/11/2005US20050176009 Polymorphic olfactory receptor genes and arrays, kits and methods utilizing information derived therefrom for genetic typing of individuals
08/11/2005US20050176008 Single strand polynucleotide sequence for suppression of genic action; gene expression inhibition; antisense agents
08/11/2005US20050175986 Human monoclonal antibody
08/11/2005US20050175617 Tie-2 ligands, methods of making and uses thereof
08/11/2005US20050175591 For efficient mRNA termination/translation; using this shorter dual termination/polyadenylation signal and avoiding the need for large and cumbersome polyadenylation signals, expression vectors may be engineered to carry considerably larger genes
08/11/2005US20050175584 Functionalized colloidal metal compositions and methods
08/11/2005US20050173334 Non-luminescent substrate
08/11/2005DE102004002351A1 New RNA aptamers specific for lipopolysaccharide-binding protein, useful for diagnosis and treatment of sepsis, inhibit the lipopolysaccharide-induced signaling cascade
08/11/2005CA2556849A1 Inhibition of bright function as a treatment for excessive immunoglobulin production
08/11/2005CA2554755A1 Functionalized colloidal metal compositions and methods
08/11/2005CA2554599A1 Novel brain natriuretic peptide variants and methods of use thereof
08/11/2005CA2554466A1 Branched polymeric sugars and nucleotides thereof
08/11/2005CA2554440A1 Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of breast cancer
08/11/2005CA2553676A1 Human soluble neuropilin-1 primary polyadenylation signal and uses thereof
08/11/2005CA2553187A1 Heterodimeric follicle stimulating hormone-fc (fsh-fc) fusion proteins for the treatment of infertility
08/11/2005CA2553104A1 Antisense oligomers and methods for inducing immune tolerance and immunosuppression
08/11/2005CA2552391A1 Oligonucleotide and the use thereof for modulating an isoform c beta-1 protein-kinase in the form of a skin depigmentation agent
08/11/2005CA2549263A1 Systems for tightly regulated gene expression
08/11/2005CA2548465A1 System and methods for nucleic acid and polypeptide selection
08/10/2005EP1562045A2 Bioarray chip reaction apparatus and its manufacture
08/10/2005EP1560931A2 Functional and hyperfunctional sirna
08/10/2005EP1560929A2 Polynucleotides for the amplification and detection of chlamydia trachomatis and neisseria gonorrhoeae
08/10/2005EP1560925A2 Inhibitors of inflammatory gene activity and cholesterol biosynthesis
08/10/2005EP1560924A2 Molecular lymphatic mapping of sentinel lymph nodes
08/10/2005EP1560918A2 Compositions and methods for the modulation of viral maturation
08/10/2005EP1560840A2 Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
08/10/2005EP1560839A2 Chimeric oligomeric compounds and their use in gene modulation
08/10/2005EP1560838A1 Labelled nucleotides
08/10/2005EP1560597A2 Differentially expressed genes involved in cancer, the polypeptides encoded thereby, and methods of using the same
08/10/2005EP1499895A4 Functionalized nanoparticles and methods of use
08/10/2005EP0877811B1 Mutated prenyl diphosphate synthases
08/10/2005CN1653177A Muteins of placental growth factor type 1, preparation method and application thereof
08/10/2005CN1653079A Intercalator containing pseudonucleotide(s)
08/10/2005CN1651575A Structure of antisense digonucleotide for inhibiting fibronectin expression and use
08/10/2005CN1651457A Nucleotide sequences of HIV-1 group (or subgroup) o retroviral antigens
08/10/2005CN1651450A Small interference RNA molecule (SiRNA) capable of effectively killing and wounding tumour cell pointed at PLK1 mRNA, its mixture and use
08/10/2005CN1214113C Gene sequence of Japanese shistosome China mainland strain gynecophoric canal protein
08/10/2005CA2496146A1 Stabilization of linear double-stranded dna in the presence of exonucleases
08/09/2005US6928368 Gene mining system and method
08/09/2005US6927056 Proteases
08/09/2005US6927044 IL-1 receptor based cytokine traps
08/09/2005US6927040 Polpeptide for use in the treatment of granulomatosis, nervous system and skin disorders, bacterial infections and leishmania
08/09/2005CA2348689C Combinatorial strategies for polymer synthesis
08/06/2005CA2553946A1 Antibodies against clostridium difficile toxins and uses thereof
08/04/2005WO2005071115A1 Activatable probes and methods for in vivo gene detection
08/04/2005WO2005070967A2 Anti-cancer antibodies with reduced complement fixation
08/04/2005WO2005070966A2 Fusion polypeptides capable of activating receptors
08/04/2005WO2005070957A1 Hcv rna-dependent rna polymerase
08/04/2005WO2005070946A1 Ribonucleic acid compound and method of liquid-phase synthesis of oligonucleic acid compound
08/04/2005WO2005070859A1 Fluorous supports and processes for production of oligonucleotide derivatives with the same
08/04/2005WO2005070104A2 REAL-TIME POLYMERASE CHAIN REACTION-BASED GENOTYPING ASSAY FOR β2-ADRENERGIC RECEPTOR SINGLE NUCLEODITE POLYMORPHISM
08/04/2005WO2005069994A2 Folate conjugates and complexes
08/04/2005WO2005069986A2 Chimeric promoters for use in plants
08/04/2005WO2005063787A3 Propargyl substituted nucleoside compounds and methods
08/04/2005WO2005059131A3 Protein binding miniature proteins and uses thereof
08/04/2005WO2005056020A3 Nf-kb oligonucleotide decoy molecules
08/04/2005WO2005049793A3 Methods and compositions for combinatorial approaches to cancer gene therapy
08/04/2005WO2005044859A3 Cd20 antibodies with increased fc receptor binding affinity and effector function
08/04/2005WO2005027723A3 Real time assay for rotavirus
08/04/2005WO2005023994A3 Modified oligonucleotides for telomerase inhibition
08/04/2005WO2005019471A3 Periostin-like factor: compositions and methods for making and using the same
08/04/2005WO2005018414A3 Detection of somatic cells in milk
08/04/2005WO2005015155A3 Methods for comparing relative flux rates of two or more biological molecules in vivo through a single protocol
08/04/2005WO2004080273A3 Compositions and methods for diagnosing and treating prostate cancer
08/04/2005WO2004064782A3 Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides