Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
09/2005
09/15/2005US20050203047 Methods for transcription and expression of nucleic acids into organisms; in particular, invention comprises a tRNA vector system to deliver and express short interfering nucleic acid, small interfering (siRNA), micro RNA (miRNA) and antisense (asRNA) into organism with high efficiency; pain treatment
09/15/2005US20050203045 Antisense modulation of cellular inhibitor of Apoptosis-2 expression
09/15/2005US20050203044 Small-mer having about 3 to about 6 nucleotides and having antiviral or antiproliferative activity or both; useful in therapeutic, diagnostic, target validation, and genomic discovery applications; capable of inhibiting viral replication
09/15/2005US20050203043 Identification of toxic nucleotide sequences
09/15/2005US20050203042 Oligomeric compounds for the modulation of Bcl-2
09/15/2005US20050203041 Antisense compound and method for selectively killing activated T cells
09/15/2005US20050203040 siNA molecule comprising a double-stranded structure that down-regulates expression of vascular cell adhesion molecule (VCAM), wherein said siNA molecule does not require the presence of nucleotides having a 2'-hydroxy group within the siNA molecule for mediating RNA interference
09/15/2005US20050203038 Modulation of ACE2 expression
09/15/2005US20050203026 Rosacea; vascular endothelial growth factor inhibitors; protease inhibitors such as Bowman-Birk Inhibitor, soybean trypsin inhibitor, and Eglin chymotrypsin inhibitor
09/15/2005US20050203009 Inhibiting VPAC1 (Vasoactive intestinal peptide)-mediated tumorigenesis; inhibits binding of pituitary adenylate cyclase-activating polypeptide (PACAP) to cell membranes
09/15/2005US20050203007 Eglin c based drugs for treatment of disease
09/15/2005US20050202565 Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence
09/15/2005US20050202552 Proteins producing an altered immunogenic response and methods of making and using the same
09/15/2005US20050202551 Proteins producing an altered immunogenic response and methods of making and using the same
09/15/2005US20050202547 Allows the above microorganism to use cyclododecanol and cyclododecanone (12-membered ring compounds) as sole carbon source for growth and energy
09/15/2005US20050202537 Methods and compositions for producing secreted trimeric receptor analogs and biologically active fusion proteins
09/15/2005US20050202535 Fusion protein comprising bowman-kirk, soybean trypsin and eglin C inhibitors for use in treatment and prevention of inflammatory, arthritic and skin disorders
09/15/2005US20050202532 Amino acid sequences for prevention and treatment of cardiovascular disease
09/15/2005US20050202531 Receptor protein for identifying modulators to treat and prevent inflammatory, antherosclerotic and cancer disorders; wound healing agents
09/15/2005US20050202528 Polypeptides involved in the biosynthesis of spiramycins, nucleotide sequences encoding these polypeptides and applications thereof
09/15/2005US20050202526 Secreted and transmembrane polypeptides and nucleic acids encoding the same
09/15/2005US20050202519 Mutated abl kinase domains
09/15/2005US20050202503 Displacement assay for detection of small molecules
09/15/2005US20050202501 Using sequencing by hybridization as tool in detecting variance in genic sequences; identifying restriction fragment length polymorphism and/or single nucleotide polymorphisms
09/15/2005US20050202496 Secreted and transmembrane polypeptides and nucleic acids encoding the same
09/15/2005US20050202480 Stabilization of linear double-stranded DNA in the presence of exonucleases
09/15/2005US20050202479 Methods and materials relating to insulin growth factor-like (IGFL) polypeptides and polynucleotides
09/15/2005US20050202477 Nucleic acid probe for use in screening and identifying grampositive bacteria
09/15/2005US20050202475 Using chimeric membrane protein as diagnostic/prognostic indicator of cell proliferative disorders
09/15/2005US20050202467 Nucleotide sequences coding serotonin receptor (5-HT1A receptor) for use in identifying modulators for prevntion and treatment of neuropsychiatric disorders
09/15/2005US20050202460 Methods and compositions for detecting Bacillus species
09/15/2005US20050202459 Non-natural polynucleotide formed via fluid comprising template and intercalator, and ligating
09/15/2005US20050202456 Processes for detecting or quantifying analytes of interest
09/15/2005US20050202455 Process for producing two or more copies of nucleic acids in a library, and process for detecting or quantifiying more than one nucleic acid in a library
09/15/2005US20050202450 Polypeptides stable under hypoxic and nonhypoxic conditions; antihypoxic agents; myocardial necrosis and arrhythmia, strokes, autoimmune deseases, neurodegenerative disorders
09/15/2005US20050202443 Type II restriction endonuclease and application thereof
09/15/2005US20050202441 Methods of designing, synthesizing, and propagating reference nucleic acids
09/15/2005US20050202437 Expression vector comprised of lactobacillus and heterologous gene sequences for use as gene therapeutic tools; enhancing expression of exogenous gene sequences
09/15/2005US20050202436 Target-specific multiple sequencing primer pool for microbial typing and sequencing applications in DNA-sequencing technologies
09/15/2005US20050202432 Plurality of genes differentially expressed in kidney cells after exposure to hormone; identifying agents which enhance calcium uptake in post-menopausal women; diagnosing and treating cardiovascular disorders
09/15/2005US20050202424 Membrane protein for use as tool in identifying modulators for treatment of phenotype-mediated antibiotic-resistance; microbiocides; bactericides; preventing infection in cystic fibrosis patients
09/15/2005US20050202419 Peroxide-driven cytochrome P450 oxygenase variants
09/15/2005US20050202417 Oligonucleotide probe for determining concentration of viral genomes in biological fluids
09/15/2005US20050202416 Gene-specific polynucleotide primers for identifying coronavirus particles in biological fluids
09/15/2005US20050202396 Microarray with increased flexibility for use in gene expression analysis
09/15/2005US20050202077 Targeted delivery of RNA interference molecules
09/15/2005US20050202022 Polynucleotides encoding humanized antibodies against human 4-1BB
09/15/2005US20050202021 Anti-cancer antibodies with reduced complement fixation
09/15/2005US20050202019 Therapeutic and diagnostic applications based on the role of the CXCR-4 gene in tumorigenesis
09/15/2005US20050201976 Selective inhibitors of nuclear factor-kappaB activation and uses thereof
09/15/2005US20050201975 Modifying chemokine G-protein mediated signalling and/or signal transduction by administering a modulator of the Notch signalling pathway; using a fusion protein of a segment of a Notch ligand extracellular domain and an immunoglobulin Fc segment or a polynucleotide encoding it; antiinflammatory agents
09/15/2005US20050201937 Creation of a gradient of isotope enrichment; ability to measure a multiplicity of isotope enrichments simultaneously
09/15/2005DE102004009704A1 New conjugates useful for labeling nucleic acids comprise a label coupled to nucleotide or nucleoside molecules through polymer linkers
09/15/2005CA2560066A1 Natural igm antibodies and inhibitors thereof
09/15/2005CA2559114A1 Compounds for hydrolysing ribonucleic acids (rnas)
09/15/2005CA2558960A1 Lactobacillus acidophilus nucleic acid sequences encoding carbohydrate utilization-related proteins and uses therefor
09/15/2005CA2558667A1 Antisense oligonucleotides for inhibiting the formation of metastases in cancer
09/15/2005CA2558510A1 Thrombomodulin (thbd) haplotypes predict outcome of patients
09/15/2005CA2557819A1 Magnetic device for isolation of cells and biomolecules in a microfluidic environment
09/15/2005CA2557818A1 Photocleavable fluorescent nucleotides for dna sequencing on chip constructed by site-specific coupling chemistry
09/15/2005CA2557661A1 Nucleic acid complexes
09/15/2005CA2557571A1 Toll-like receptor 2 (tlr-2) haplotypes predict outcome of patients
09/15/2005CA2557353A1 Immunogenic compositions for chlamydia pneunomiae
09/14/2005EP1574577A2 Growth differentiation factor-11
09/14/2005EP1574572A1 Compounds for hydrolysing ribonucleic acids (RNAs)
09/14/2005EP1573070A2 pRNA CHIMERA
09/14/2005EP1573065A2 Methods for rapid forensic analysis of mitochondrial dna and characterizationg of mitochondrial dna heteroplasmy
09/14/2005EP1573045A2 Heart failure gene determination and therapeutic screening
09/14/2005EP1573038A2 A high resolution typing system for pathogenic mycobacterium tuberculosum
09/14/2005EP1573036A2 Subtelomeric dna probes and method of producing the same
09/14/2005EP1573035A2 Brother of the regulator of imprinted sites (boris)
09/14/2005EP1573031A2 Androgen regulated nucleic acid molecules and encoded proteins
09/14/2005EP1573024A2 Nuleic acids and corresponding proteins useful in the detection and treatment of various cancers
09/14/2005EP1573023A2 Nucleic acid and corresponding protein entitled 162p1e6 useful in treatment and detection of cancer
09/14/2005EP1573009A2 Detection of small nucleic acids
09/14/2005EP1572987A2 Novel nucleic acids and polypeptides
09/14/2005EP1572978A2 Bead bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries
09/14/2005EP1572977A2 Assay and compositions for detection of bacillus anthracis nucleic acid
09/14/2005EP1572975A2 Streptococcus uberis adhesion molecule
09/14/2005EP1572970A2 Inhibitory oliogonucleotides targeted to bcl-2
09/14/2005EP1572967A2 Il-1 receptor based antagonists and methods of making and using
09/14/2005EP1572965A2 Human sarcoma-associated antigens
09/14/2005EP1572964A2 Double-stranded rna structures and constructs, and methods for generating and using the same
09/14/2005EP1572960A2 Identification of a novel bitter taste receptor, t2r76
09/14/2005EP1572953A2 Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, bgs42
09/14/2005EP1572952A2 Novel polynucleotide and polypeptide sequences and uses thereof
09/14/2005EP1572941A2 Novel flavivirus antigens
09/14/2005EP1572938A2 Polyvalent cation-sensing receptor in atlantic salmon
09/14/2005EP1572929A2 Membrane-anchored beta2 microglobulin covalently linked to mhc class i peptide epitopes
09/14/2005EP1572925A2 Cancer-linked gene as target for chemotherapy
09/14/2005EP1572924A2 Contraceptive targets
09/14/2005EP1572922A2 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
09/14/2005EP1572921A2 Cytokine polypeptides
09/14/2005EP1572908A2 Chimeric molecules for cleavage in a treated host
09/14/2005EP1572907A2 Molecules interacting with casl (mical) polynucleotides, polypeptides, and methods of using the same
09/14/2005EP1572906A2 Novel nucleic acid molecules and polypeptides encoding baboon tafi
09/14/2005EP1572889A2 Nucleic acid and amino acid sequences encoding high-level expressor factor viii polypeptides and methods of use
09/14/2005EP1572886A2 Use of phosphorothiolate polynucleotides in ligating nucleic acids
09/14/2005EP1572878A2 Compositions and methods for inferring a response to a statin
09/14/2005EP1572875A2 Receptors and membrane-associated proteins