Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
08/2010
08/31/2010US7786351 Recombinant DNA constructs and methods for controlling gene expression
08/31/2010US7786296 5'-O-(4,4'-dimethoxytrityl)-thymidine-3'-O-diisopropylsilyl-4-benzoylaminobutanoic acid triethylammonium; for the synthesis of a nucleic acid oligomer containing modified bases that are unstable under a basic condition
08/31/2010US7786295 Quantitative analysis; cloning; sequence determination; lysis separation
08/31/2010US7786294 Compositions and methods for amplification and cloning of near full-length viral genome samples
08/31/2010US7786293 For solid phase synthesis of phosphorothioate-containing antisense oligonucleotides; gene expression inhibition
08/31/2010US7786292 compounds having a chelating moiety and an oligonucleotide sequence which includes one or more modified nucleobases such as hydroxynucleobases; inhibiting translation of a nucleic acid in an organism
08/31/2010US7786291 cause RNAi-induced degradation of mRNA from the Nav1.8 sodium channel gene; for inhibiting chronic pain
08/31/2010US7786290 consisting of two single strands that exhibits increased effectiveness in inhibiting the expression of a target gene by means of RNA interference; improved stability in cells
08/31/2010US7786289 Method and kit for identifying antibiotic-resistant microorganisms
08/31/2010US7786288 A binding site of the cystosolic protein cyclophilin A on human immunodeficiency virus capsid protein, which may be expressed by a recombinant viral, bacterial or yeast carrier; may be treated with neuraminidase or trypsin to remove sialic acid; immune stimulant such as teichoic acid or zymosan
08/31/2010US7786287 Hepatitis C virus assay systems
08/31/2010US7786286 Microorganismal, outer-membrane, enzymatic polypeptide for use in developing vaccine for prevention and treatment of nesserial infection
08/31/2010US7786285 Nucleic acid, expression vectors and host cells for synthetic genes, chosen from a gram negative bacteria, yeast, or mammalian cell; zinc-endopeptidases that specifically cleave the synaptosomal proteins, SNAP-25, VAMP, or syntaxin at discrete sites
08/31/2010US7786284 Polynucleotides encoding IL-17 receptor A antigen binding proteins
08/31/2010US7786283 BRI constructs and methods of using
08/31/2010US7786281 Protein-deamidating enzyme, microorganism producing the same, gene encoding the same, production process therefor, and use thereof
08/31/2010US7786279 Nucleic acid molecules, polypeptides, antibodies and compositions for treating and detecting influenza virus infection
08/31/2010US7786278 improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer; carcinoembryonic antigen (CEA)
08/31/2010US7786275 Identification of a unique core domain of Par-4 sufficient for selective apoptosis induction in cancer cells
08/31/2010US7786272 bind to biomarker overexpressed in colon or lung tumor cells
08/31/2010US7786266 Desmocollin 2 (DSC2) specific immunoglobulin for use in prevention and treatment of cell proliferative disorders
08/31/2010US7786261 protein of an ectodomain of a transforming growth factor beta membrane-bound receptor and a peptide subunit of an alpha -helical coiled-coil; selecting compounds capable of inhibiting ligand binding and kinase activity
08/31/2010US7786092 Selective inhibition of pro-angiogenic VEGF pathway gene expression; Tissue targeted nanoparticle compositions comprising polymer (histidine-lysine copolymer) conjugates and nucleic acid molecules; antisense strand consists of the complement of SEQ ID NO: 286; ocular disease, arthritis, inflammation
08/31/2010US7786090 Methods and compositions for treating and preventing neurologic disorders
08/31/2010US7786089 modulate an immune response through toll like receptors; 5'-TCGiTCGiTTCTC-Y-GiCTTGiCAAGiCT-5' (SEQ ID NO: 1), wherein X is a glycerol linker, Y is C3-1inker and Gl is 7-deazaguanosine
08/31/2010US7786047 an immunoglobulin having determined antigen specificity, and having a variable fragment which is derived from a so-called heavy-chain immunoglobulin having two heavy polypeptide chains capable of recognizing and binding one or several antigens and which is further naturally devoid of light chains
08/31/2010US7785886 Contacting ABC1-expressing cells with a composition containing test compound and measuring biological activity by determining the level of efflux of labeled substrate ; use in treating cardiovascular disease
08/31/2010US7785881 MAGE-C2 antigenic peptides and uses thereof
08/31/2010US7785879 Pregnane X receptor compositions, crystals and uses thereof
08/31/2010US7785878 Mammalian alpha-kinase proteins, nucleic acids and diagnostic and therapeutic uses thereof
08/31/2010US7785875 Polynucleotide encoding HCV epitopes which can bind to various HLA supertypes, immunogenic composition comprising same and method of inducing an HCV-specific immune response using same
08/31/2010US7785871 Shuttle vector which utilizes homologous recombination to generate transgenic organism and express heterologus gene sequences; gene therapy and animal models
08/31/2010US7785863 Consists of a light source, a micromirror positioned to redirect light from light source toward substrate, a computer connected to and controlling micromirror and a reaction chamber is placed in the path of light redirected by mirrors
08/31/2010US7785859 Methods for displaying (poly)peptides/proteins on bacteriophage particles via disulfide bonds
08/31/2010US7785856 therapeutic fusion protein comprising amino acid residues 70-952 of human acid alpha-glucosidase (GAA) and a peptide tag; permits M6P-independent targeting of human GAA or GAA-like enzymes to patient lysosomes
08/31/2010US7785854 Heat and alkali resistant hydrolase for use in saccharification of lignocellulosic feedstocks, production of fermentable sugars and fuel alcohol, improving digestibility of feeds, pulp and paper processing and releasing dye from and softening denim
08/31/2010US7785853 Comprises heat resistant enzymatic polypeptide for bioremediation of plant biomass and pollution control; reuse
08/31/2010US7785852 Exonucleases; polymerases; solid phase synthesis
08/31/2010US7785851 having predetermined levels or more of enzyme activity and heat resistance which reduces denaturing in the enzymes
08/31/2010US7785850 Heterologus expression of trypanothione reductase from Leishmania donovani in a prokaryotic system
08/31/2010US7785849 Cyclic nucleotide-specific phosphodiesterases from Leishmania and uses thereof
08/31/2010US7785847 Method for producing optically active alcohols from alkanones using a dehydrogenase of azoarcus
08/31/2010US7785844 Modified primer for detection of DNA viruses
08/31/2010US7785843 libraries of nucleic acid species each comprising a transcription unit having a promoter region operatively linked to a coding sequence; enable the indirect detection and analysis of particular biomolecules, for example, by mass spectrometry
08/31/2010US7785842 determining a ratio of the amount or concentration of an extracellular human RNA from plasma or serum from a human that is a coding RNA comprising an open reading frame encoding an amino acid sequence to that of a noncoding human; cancer detection
08/31/2010US7785837 used to synthesize plastic materials and other products; utilize raw materials based on carbohydrates rather than hydrocarbons; produces 3-hydroxypropionic acid (3-HP) from beta-alanine
08/31/2010US7785834 Soluble TNF receptors and their use in treatment of disease
08/31/2010US7785832 Method of protein synthesis
08/31/2010US7785829 polynucleotide encoding a soluble polypeptide; for decreasing inhibition of axonal growth of a central nervous system neuron; neurological diseases, disorders and injuries such as spinal cord injury
08/31/2010US7785827 allows and facilitates production and accumulation of tRNAs that are misaminoacylated with nonstandard and noncognate amino acids; can be used to introduce novel amino acids into proteins
08/31/2010US7785802 nucleic acid molecule coding for g protein-coupled recept for use in identifying modulators of taste transductance; artificial sweetners; used as additives in foods, beverages and medicinals for blocking bitter taste
08/31/2010US7785801 Identification of surface-associated antigens for tumor diagnosis and therapy
08/31/2010US7785797 detecting the gene expression level of a nucleic acid comprising measuring the RNA level expressed by polymerase chain reaction or by hybridization to an oligonucleotide comprising DNA, RNA, cDNA, peptide nucleic acids, genomic DNA or synthetic oligonucleotides
08/31/2010US7785796 sequence determination of an immobilized target polynucleotide comprising monitoring the sequential incorporation of nucleotides complementary to the immobilized target polynucleotide; the nucleotides have a base that is linked to a detectable label via a cleavable linker; detection of the labels
08/31/2010US7785790 sequencing nucleic acids immobilized on layouts using single copies of the layouts; improved accuracy, longer read lengths of sequences and efficiency of multiplex polymerase chain reaction
08/31/2010US7785789 diagnosis autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) in humans comprising detecting homozygosity or heterozygosity of a C to T nonsense mutation and an A to G missense mutation of a DNA sequence; cleavage with Taq 1 or another enzyme which cleaves recognition site 5'-TCGA-3'
08/31/2010US7785786 Methods for detecting nucleic acids using multiple signals
08/31/2010US7785785 Charge perturbation detection system for DNA and other molecules
08/31/2010US7785784 Detection of oligonucleotides by dual hybridization
08/31/2010US7785782 Device and method for in-line blood testing using biochips
08/31/2010US7785781 performing a bioassay on a sample to determine the sequence of an allele of the P2X1 promoter gene, to determine the to likelihood of developing peripheral vascular disease, strokes and myocardial necrosis; screening for anticoagulants
08/31/2010US7785780 Assay for detecting and identifying micro-organisms
08/31/2010US7785779 Generating vector comprising regulatory sequences associated with protein translation elongation factor TU (P EF-TU); improving exogenous gene expression
08/31/2010US7785778 Porcine polymorphisms and methods for detecting them
08/31/2010US7785610 Chimeric immunomodulatory compounds and methods of using the same—III
08/31/2010CA2518861C Carboxylic acid reductase polypeptide, nucleotide sequence encoding same and methods of use
08/31/2010CA2190592C Detection and differentiation of mycobacterium tuberculosis complex bacteria by direct variant repeat oligotyping
08/31/2010CA2190371C Receptor for oncostatin m
08/26/2010WO2010096723A1 Methods for the detection and identification of extended spectrum beta lactamases
08/26/2010WO2010096418A2 Antibody molecules having specificity for human ox40
08/26/2010WO2010096394A2 Aldehyde-tagged protein-based drug carriers and methods of use
08/26/2010WO2010096201A2 Synthesis of ara-2'-o-methyl-nucleosides, corresponding phosphoramidites and oligonucleotides incorporating novel modifications for biological application in therapeutics, diagnostics, g- tetrad forming oligonucleotides and aptamers
08/26/2010WO2010094899A1 Nucleic acids specifically binding with human factor vii/viia and uses thereof
08/26/2010WO2010048317A3 Micro-rnas as markers for tumor progression
08/26/2010WO2010047835A3 Double-stranded ribonucleic acids with rugged physico-chemical structure and highly specific biologic activity
08/26/2010US20100218283 Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof
08/26/2010US20100218282 Nucleic acid molecules from rice controlling abiotic stress tolerance
08/26/2010US20100218280 Defensin-Encoding Nucleic Acid Molecules Derived From Nicotiana Alata, Uses Therefor and Transgenic Plants Comprising Same
08/26/2010US20100218279 Plant resistance to banana bunchy top virus
08/26/2010US20100218275 Method for increasing salt tolerance of plant by overexpressing syfbp/sbpase gene isolated from synechocystis and plant produced by the same
08/26/2010US20100218274 Constitutive promoter from oil palm
08/26/2010US20100218266 Methods of identifying and using snail1 inhibitory compounds in chondrodysplasia treatment and preparation of pharmaceutical compositions
08/26/2010US20100217032 Process for preparing pravastatin
08/26/2010US20100216983 Synthesis of locked nucleic acid derivatives
08/26/2010US20100216982 Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation
08/26/2010US20100216981 Antiviral agent
08/26/2010US20100216979 6-modified bicyclic nucleic acid analogs
08/26/2010US20100216978 Wireframe nanostructures
08/26/2010US20100216972 RNAi Inhibition of Alpha-ENaC Expression
08/26/2010US20100216971 RNAi Inhibition of Alpha-ENaC Expression
08/26/2010US20100216870 Novel Genes Encoding a Nystatin Polyketide Synthase and Their Manipulation and Utility
08/26/2010US20100216868 Agents, compositions and methods for treating pathologies in which regulating an ache-associated biological pathway is beneficial
08/26/2010US20100216866 RNAi Modulation of APOB and Uses Thereof
08/26/2010US20100216720 Antibodies to troponin i and methods of use thereof
08/26/2010US20100216717 Hypoallergenic Mutant Polypeptides Based on Fish Parvalbumin
08/26/2010US20100216713 Novel compositions and methods in cancer associated with altered expression of prlr
08/26/2010US20100216711 Protease-Stable, Cell Wall-Lysing Enzymes
08/26/2010US20100216710 Methods for stimulating nervous system regeneration and repair by regulating arginase i and polyamine synthesis
08/26/2010US20100216708 Fibronectin Type III Domain Based Scaffold Compositions, Methods and Uses
08/26/2010US20100216704 Novel genes and proteins that home to developing microvessels