Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
09/2010
09/28/2010US7803596 Enzyme derived from thermophilic organisms that functions as a chromosomal replicase, and preparation and uses thereof
09/28/2010US7803595 Mammalian sphingosine kinase type 2 isoforms, cloning, expression and methods of use thereof
09/28/2010US7803594 Recombinant arginine methyltransferase encoded by nucleic acid sequences of Trypanosoma brucei
09/28/2010US7803593 Nucleic acid molecule that encodes the MGAT-X1 protein; pharmaceutical composition containing the nucleic acid or its expression vector
09/28/2010US7803592 Substrate specificity for glucose is improved by substituting another amino acid residue for the amino acid residue at position 472 and/or 475; sensors, assay kits
09/28/2010US7803591 Polynucleotide coding for a multimeric oxidoreductase complex having an alpha subunit, a gamma subunit and a cytochrome C subunit with specific amino acid sequences; used to manufacture of L-ascorbic acid
09/28/2010US7803584 Cultivating an Escherichia coli that has been modified to attenuate expression of the sraL gene and collecting L-threonine and/or L-lysine from the medium
09/28/2010US7803580 Detecting the methylation status of a target region of a nucleic acid molecule using an intercalating nucleic acid containing two or more internal intercalating pseudonucleotides, preferably a phosphoramidite of 1-(4,4'-dimethoxytriphenylmethyloxy)-3-pyrenemethyloxy-2-propanol
09/28/2010US7803579 Strand displacement amplification is used to synthesize a nucleic acid having a sequence complementary to a target sequence by using a primer designed so that it is capable of forming a stem-loop structure by the extension of the primer and satisfies additional specific requirements
09/28/2010US7803578 A gene encoding a protein having an improved nitrile hydratase activity, whereby heat resistance has been improved or substrate specificity has been changed; for efficient production of acrylamide
09/28/2010US7803577 Polynucleotide encoding a tropoelastin polypeptide; expression products and hybrid molecules of the derivatives and variants
09/28/2010US7803575 Use of heat-stable carbonic anhydrase in CO2 separation, e.g., from flue gas, natural gas or biogas; carbonic anhydrase with a specific structure, polynucleotide encoding the enzyme, recombinent expression vector and host cell, and carbonic anhydrase biosynthesis
09/28/2010US7803569 Atherothrombosis risk in an individual is indicated by an FSAP protein concentration that is reduced compared to the FSAP protein concentration in the standard sample
09/28/2010US7803562 Method for screening human intestinal Npt2B modulatory agents
09/28/2010US7803560 Contacting a candidate antagonist with a MCP-1 receptor polypeptide having an amino acid sequence at least 95% homologous to an extracellular domain of a specific sequence, and comparing the binding of MCP-1 to the receptor polypeptide; decreased binding indicates an antagonist
09/28/2010US7803552 Biomarkers for predicting prostate cancer progression
09/28/2010US7803551 Amplifying the target nucleic acid with primers in the presence of a double-stranded DNA binding dye; monitoring fluorescence of the dye; melting curve is generated for the target nucleic acid by measuring fluorescence from the dsDNA binding dye as the mixture is heated.
09/28/2010US7803548 Determining the presence or absence of the 1484G->T mutation in both alleles of the CF transmembrane regulatory gene; if the human is homozygous for the mutation, s/he has cystic fibrosis; is a carrier if heterozygous; and has no predisposition or carrier status if mutation is absent in both alleles
09/28/2010US7803547 Using primer amplification to identify lepidopteran insect resistant cotton; biological pest control
09/28/2010US7803546 Method of screening for sensitivity to kinase inhibitor therapy
09/28/2010US7803545 Genotyping preferential genetic disorders via characterizing heteroduplex DNA ; allelic variation and disease diagnosis
09/28/2010US7803541 Different nucleic acids are captured through cooperative hybridization events on different, identifiable subsets of particles or at different selected positions on a spatially addressable solid support.
09/28/2010US7803540 Immobilizing first and second probes on a substrate, hybridizing the probes with first and second hurdle DNAs probes, hybridizing the target DNA with the hybrids, and determining the ratio of a signal of the target DNA hybridized to the first probe to a signal of the DNA hybridized to the second probe
09/28/2010US7803539 Method of isolating and purifying nucleic acids using immobilized hydrogel or PEG-hydrogel copolymer
09/28/2010US7803537 by direct sample immobilization onto microspheres of an array comprising a patterned surface of discrete sites that can associate the individual microspheres
09/28/2010US7803536 Methods of detecting fluorescence with anthraquinone quencher dyes
09/28/2010US7803535 Predicting the likelihood of an incidence of graft versus host diseases by detecting the presence at least one of the polymorphisms Nod2-SNP8, Nod2-SNP12, Nod2-SNP13 in the NOD2/CARD15 gene
09/28/2010US7803532 Diagnosis of Sezary syndrome (a type of lymphoma) by analyzing a nucleic acid sample from a human patient to detect the presence or the absence of a neuron navigator 3 gene and diagnosing Sezary syndrome when the gene is absent
09/28/2010US7803531 Anticancer, antitumor agents
09/28/2010US7803530 Detection and typing of human papillomavirus using PNA probes
09/28/2010US7803528 Real-time monitoring of nucleic acid amplification using a first probe that is a fluorophore capable of hybridizing to the nucleic acid, and a second probe capable of hybridizing to the first probe, has a molecule which quenches said first probe, and is longer than the first probe; detectng fluorescence
09/28/2010US7803525 Detecting a specific nucleic acid sequence of at least 13 contiguous nucleotides or the reverse complement sequence by using quantitative real-time reverse transcriptase polymerase chain reaction
09/28/2010US7803399 Delivery system for nucleic acids
09/28/2010US7803388 Polymorphic membrane proteins or PMPs of Chlamydia, amino acid and nucleotide sequences; immunogens; vaccines; biodrugs;respiratory system disorders; urogenital system disorders; genetic engineering
09/28/2010US7803377 Anti-DLL4 antibodies and methods using same
09/28/2010US7803365 Ex vivo and in vivo expression of the thrombomodulin gene for the treatment of cardiovascular and peripheral vascular diseases
09/28/2010CA2415493C Cation mediated triplex hybridization assay
09/28/2010CA2407726C Sulfonated [8,9]benzophenoxazine dyes and the use of their labelled conjugates
09/28/2010CA2382631C Poly(ether-thioether), poly(ether-sulfoxide) and poly(ether-sulfone) nucleic acids
09/28/2010CA2270400C Mutant penicillin g acylases
09/28/2010CA2188017C Cardiotrophin and uses therefor
09/28/2010CA2153494C Novel parasitic helminth proteins
09/27/2010CA2660622A1 Rig-i mutations and uses thereof in diagnostic and therapeutic virus-dependent immune applications
09/23/2010WO2010108192A1 Mirnas as therapeutic targets in cancer
09/23/2010WO2010108040A1 Inhibitors of viral integrase and methods of use
09/23/2010WO2010107952A2 RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
09/23/2010WO2010107891A1 Compositions for use in identification of salmonella
09/23/2010WO2010107838A1 Targeting apolipoprotein b for the reduction of apolipoprotein c-iii
09/23/2010WO2010107740A2 Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1
09/23/2010WO2010107733A2 Treatment of nuclear factor (erythroid-derived 2)-like 2 (nrf2) related diseases by inhibition of natural antisense transcript to nrf2
09/23/2010WO2010107709A1 Protein production in microorganisms of the phylum labyrinthulomycota
09/23/2010WO2010105372A1 Compositions and methods for silencing hepatitis c virus expression
09/23/2010WO2010088668A3 Methods of detecting sepsis
09/23/2010WO2001051665A9 Nanoparticles having oligonucleotides attached thereto and uses therefor
09/23/2010US20100242141 Composition for production of plant body having improved sugar content, and use thereof
09/23/2010US20100242138 ODP1-2 Genes and Uses Thereof in Plants
09/23/2010US20100242137 Polynucleotides encoding proteins involved in plant metabolism
09/23/2010US20100242136 Udp-glucose modifiers
09/23/2010US20100242134 Methods and polynucleotides for improving plants
09/23/2010US20100242128 Method to produce modified plants with altered n-glycosylation pattern
09/23/2010US20100242126 Regulator of ephrin-Eph receptor signaling and mouse having abnormal ephrin-Eph receptor signaling mechanisms
09/23/2010US20100240882 Apparatus, System and Method for Purifying Nucleic Acids
09/23/2010US20100240881 Therapeutic compositions
09/23/2010US20100240880 Ab initio generation of single copy genomic probes
09/23/2010US20100240873 Ligand (act-4-l) to a receptor on the surface of activated cd4+ tcells
09/23/2010US20100240870 Composite organic-inorganic nanoclusters
09/23/2010US20100240869 Gene related to growth promoting function of acetic acid bacterium, acetic acid bacterium bred using the gene and method for producing vinegar using the acetic acid bacterium
09/23/2010US20100240738 Antisense modulation of kinesin-like 1 expression
09/23/2010US20100240736 Novel Compounds for the Treatment or Alleviation of Edema, and Methods for their Use
09/23/2010US20100240734 Methods and compositions for the specific inhibition of gene expression by double-stranded rna
09/23/2010US20100240732 Aptamer-targeted sirna to prevent attenuation or suppression of a t cell function
09/23/2010US20100240730 RNA Interference Mediated Inhibition of Gene Expression Using Chemically Modified Short Interfering Nucleic Acid (siNA)
09/23/2010US20100240687 Method for checking and controlling the mammalian lactic acid fermentation process/aerobic glucose fermentation metabolic pathway in mammalian organism
09/23/2010US20100240673 EML4-ALK Fusion Gene
09/23/2010US20100240583 Soluble protein and utilization of the same
09/23/2010US20100240582 Peptides and related molecules that modulate nerve growth factor activity
09/23/2010US20100240574 Heyl as a Therapeutic Target and a Diagnostic Marker for Neoplasia and Uses Therefor
09/23/2010US20100240554 siRNA Targeting Glucagon Receptor (GCGR)
09/23/2010US20100240553 Primer set and probe for detection of human papillomavirus
09/23/2010US20100240552 Method for evaluation of drug sensitivity by analysis of pomc gene
09/23/2010US20100240544 Aptamer biochip for multiplexed detection of biomolecules
09/23/2010US20100240133 Compositions and Methods for Transposon Mutagenesis of Human Embryonic Stem Cells
09/23/2010US20100240125 Bone delivery conjugates and method of using same to target proteins to bone
09/23/2010US20100240106 Mutant enzymes
09/23/2010US20100240103 Oligonucleotides labeled with a plurality of fluorophores
09/23/2010US20100240102 Methods and compositions for multiple displacement amplification of nucleic acids
09/23/2010US20100240101 Parallel Proximity Ligation Event Analysis
09/23/2010US20100240100 Human antibodies that have mn binding and cell adhesion-neutralizing activity
09/23/2010US20100240096 Novel hemopoietin receptor protein, nr10
09/23/2010US20100240095 Polypeptides having cellobiohydrolase II activity and polynuleotides encoding same
09/23/2010US20100240093 Isolated Staphylococcus Pseudolugdunensis
09/23/2010US20100240084 Use of the protien maba (fabg1) of mycobacterium tuberculosis for designing and screening antibiotics
09/23/2010US20100240065 Prolyl Hydroxylase Compositions and Methods of Use Thereof
09/23/2010US20100240064 Differential enzymatic fragmentation
09/23/2010US20100240059 Maize event dp-098140-6 and compositions and mehtods for the identification and/or detection thereof
09/23/2010US20100240054 Identification and isolation of fetal cells and nucleic acid
09/23/2010US20100240049 Methods of Detecting Cervical Cancer
09/23/2010US20100240042 Method of detecting methylated cytosine
09/23/2010US20100240039 Fhl1 mutations associated with novel x-linked muscular myopathies
09/23/2010US20100240034 Gene defects and mutant ALK kinase in human solid tumors