Patents
Patents for C07D 473 - Heterocyclic compounds containing purine ring systems (11,932)
02/2003
02/25/2003US6525059 Substituted pyrazoles as p38 kinase inhibitors
02/25/2003US6525032 Agonists of human adenosine receptors useful as anti-inflammatory agents in treatment of diseases of respiratory tract; chemical intermediates
02/25/2003CA2113080C Topical composition containing penciclovir
02/20/2003WO2003014296A2 A group of novel anti-cancer compounds with specific structure
02/20/2003WO2003013528A1 Substituted pyridin-4-ones and their use as gonadotropin-releasing hormone receptor antagonists.
02/20/2003US20030036543 Especially as inhibitors of Aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.
02/20/2003CA2456144A1 A group of novel anti-cancer compounds with specific structure
02/20/2003CA2455871A1 Substituted pyridin-4-ones and their use as gonadotropin-releasing hormone receptor antagonists.
02/19/2003EP1119571B1 Tricyclic delta3-piperidines as alpha2-antagonists
02/19/2003CN1101816C Substituted purine derivatives, processes for their prepn. their use, and compsns. comprising them
02/18/2003US6521620 Suppressing tumors, especially breast cancers; antiproli-ferative agents; arthritis, vascular restenosis, psoriasis and angiogenesis; extremely low cytotoxicity
02/13/2003WO2003011864A1 DERIVATIVES OF TRIAZOLYL-IMIDAZOPYRIDINE AND OF THE TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A2a RECEPTOR AND THEIR USE AS MEDICAMENTS
02/13/2003WO2003011863A1 Novel crystal forms of 9-substituted hypoxanthine derivatives
02/13/2003WO2003011297A1 N3-substituted 6-anilinopyrimidines and methods to treat gram-positive bacterial and mycoplasmal infections
02/13/2003US20030032804 Methods of treating periodontal disease
02/13/2003CA2417337A1 Novel crystal forms of 9-substituted hypoxanthine derivatives
02/11/2003US6518425 A process for producing a 1,3-oxathiolane nucleoside comprising reacting a 5-halo-2-protected-oxymethyl-1,3-oxathiolane with a silylated purine or pyrimidine without the addition of a Lewis acid or an additional base to the reaction
02/11/2003US6518314 Pharmaceutical agents that impede the initiation and progression of primary and secondary DMS disruptions
02/11/2003US6518286 Compounds
02/11/2003US6518277 Disrupting leukocyte function
02/11/2003CA2092305C Compounds having antihypertensive and anti-ischemic properties
02/06/2003WO2002059112A3 Pyrazole compounds useful as protein kinase inhibitors
02/06/2003US20030028026 Nitrate salts of Salbutamol, Cetirizine, Loratadine, Terfenadine, Emedastine, Ketotifen, Nedocromil, Ambroxol, Dextromethorphan, Dextorphan, Isoniazide, Erythromycin, and Pyrazinamide; respiratory system pathology treatment
02/05/2003CN1395566A Corticotropin releasing factor antagonists
02/04/2003US6514977 For treating p38 kinase mediated disorders
02/04/2003US6514664 Radiation sensitive compositions containing image quality and profile enhancement additives
01/2003
01/30/2003WO2003007942A1 Substituted isoindoles and the use thereof
01/30/2003WO2002088079A3 Dual inhibitors of pde 7 and pde 4
01/30/2003US20030023087 Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use
01/30/2003US20030022885 Pyrazole compounds useful as protein kinase inhibitors
01/30/2003CA2453650A1 Substituted isoindoles and the use thereof
01/29/2003EP1278748A2 Inhibitors of human phosphatidyl-inositol 3-kinase delta
01/29/2003EP1278741A1 Muscarinic agonists
01/29/2003EP1278515A1 Pharmaceutical formulation comprising carrier beads coated with a layer of valaciclovir
01/28/2003US6511998 Pyrazole carboxamides useful for the treatment of obesity and other disorders
01/28/2003US6511984 Neuropeptide Y antagonists
01/28/2003US6511977 For preventing or treating cardiac arrhythmia or atrial arrhythmia
01/28/2003CA2108369C Method and composition for ameliorating the adverse effects of aging
01/23/2003WO2003006465A1 Partial and full agonist of a adenosine receptors
01/23/2003WO2003006423A1 N-(3-amino-2-hydroxy-propyl) substituted alkylamide compounds
01/23/2003WO2003005969A2 Tetrahydropurinones as corticotropin releasing factor
01/23/2003WO2002050066A3 Pyrazole compounds useful as protein kinase inhibitors
01/23/2003WO2002004448A3 Methods for treatment of drug-induced peripheral neuropathy and related conditions
01/23/2003US20030018189 Cyclic polyamines having total 9-24 members which have activity in against HIV-infected cells as well as other biological activity related to binding of ligands to chemokine receptors
01/23/2003US20030018038 1,4 substituted piperidinyl NMDA/NR2B antagonists
01/23/2003CA2453503A1 N-(3-amino-2-hydroxy-propyl) substituted alkylamide compounds
01/22/2003EP0888348B1 Acyclic nucleoside derivatives
01/22/2003EP0880521B1 Synthesis of acyclic nucleosides
01/21/2003US6509356 1-(4-(Substituted alkoxy)benzyl)naphthalene compounds having estrogen inhibitory activity
01/16/2003WO2003004496A1 Dpp-iv-inhibiting purine derivatives for the treatment of diabetes
01/16/2003WO2003004488A1 Indazole benzimidazole compounds as tyrosine and serine/threonine kinase inhibitors
01/16/2003WO2002050062A3 Benzimidazole and pyridylimidazole derivatives as ligands for gaba receptors
01/16/2003US20030013847 Pyruvate derivatives
01/16/2003US20030013846 Cytoprotective agents
01/16/2003US20030013727 Therapy for sexual disorders
01/16/2003US20030013724 Novel prolines as antimicrobial agents
01/16/2003US20030013721 Antiinflammatory agents; immunology; cardiovascular disorders; rheumatic disorders
01/16/2003US20030013660 Dioxolane analogs for improved inter-cellular delivery
01/16/2003US20030013657 Reducing oxidation stresses; central nervous system disorders; antiinflammatory agents
01/16/2003US20030013656 Reducing oxidation stresses; central nervous system disorders; antiinflammatory agents
01/15/2003EP1274701A1 Chemical compounds
01/15/2003EP0584347B1 Enantiomeric hydroxylated xanthine compounds
01/15/2003CN1391558A Substituted 1,3-diaryl-2-pyridine-2-yl-3-(pyridine-2-ylamino)-propanol derivatives, methods for their production, pharmaceutical compositions containing the same and their use
01/15/2003CN1098687C Use of aminopurine antiviral agents for treatment and prophylaxis of latent herpesvirus infections
01/15/2003CN1098686C Use of xanthine derivatives for reducing pathological hyper-reactivity of eosinophilic granulocytes, xanthine compounds and process for producing them
01/14/2003US6506876 LTA4 hydrolase inhibitor pharmaceutical compositions and methods of use
01/14/2003US6506770 Antiviral compounds
01/14/2003US6506768 Tetrahydro γ-carbolines
01/14/2003US6506762 Certain alkylene diamine-substituted heterocycles
01/09/2003WO2003002566A1 Purine derivatives as a2b adenosine receptor antagonists
01/09/2003WO2003002565A1 2,6,9-substituted purine derivatives and their use n the treatment of proliferative disorders
01/09/2003WO2003002564A1 Improved synthesis of branched acyclic nucleosides
01/09/2003WO2003002122A1 Beta-hydroxyamine derivatives useful in treatment of alzheimer's disease
01/09/2003WO2003001881A2 Cell-based high-throughput screening methods
01/09/2003WO2002059111A3 Pyrazole compounds useful as protein kinase inhibitors
01/09/2003US20030008865 Xanthine-and phenazone-acesulfame-H complexes having improved taste, process for their preparation and their use
01/09/2003US20030008842 Formulations of adenosine a1 agonists
01/09/2003CA2452039A1 Beta-hydroxyamine derivatives useful in treatment of alzheimer's disease
01/09/2003CA2451795A1 Cell-based high-throughput screening methods
01/09/2003CA2450575A1 Improved synthesis of branched acyclic nucleosides
01/03/2003WO2003000689A1 Imidazo`1,2-a!pyridine derivatives for the prophylaxis and treatment of herpes viral infections
01/03/2003WO2002066020A3 Modulation of gsk-3beta activity and its different uses
01/03/2003WO2002004452A3 Methods for treatment of disease-induced peripheral neuropathy and related conditions
01/03/2003WO2002004451A3 Methods for stimulation of synthesis of synaptophysin in the central nervous system
01/03/2003CA2451008A1 Imidazo¬1,2-a]pyridine derivatives for the prophylaxis and treatment of herpes viral infections
01/02/2003US20030004330 Methods for producing nucleoside derivatives and intermediates therefor
01/02/2003US20030004173 Pharmaceutically active compounds
01/02/2003US20030004164 Anticancer agents; autoimmune diseases
01/02/2003US20030004161 Anticancer agents; autoimmune diseases
01/02/2003US20030003505 Nucleobase heterocyclic combinatorialization
01/02/2003EP1270574A1 Caffeine complexes with improved flavour, process for their preparation and their use
01/02/2003EP1270573A1 Xanthine and phenazone acesulfam-H complexes with improved taste, process for their preparation and their use
01/02/2003EP1268480A1 8-quinolinxanthine and 8-isoquinolinxanthine derivatives as pde 5 inhibitors
01/01/2003CN1388123A Chloropyrimidine intermediate
12/2002
12/31/2002US6500946 Low cost, simple, high yield production, including that of antiviral agent 9-(2,3-dideoxy-2-fluoro-.beta.-d-threo-pentofuranosyl)adenine (fdda)
12/27/2002WO2002102315A2 QUINAZOLINE AND PYRIDO[2,3-d]PYRIMIDINE INHIBITORS OF PHOSPHODIESTERASE (PDE) 7
12/27/2002WO2002102314A2 Purine inhibitors of phosphodiesterase (pde) 7
12/27/2002WO2002102313A2 Pyrimidine inhibitors of phosphodiesterase (pde) 7
12/27/2002WO2002074753A3 5-phenylpyrimidine, methods and intermediate products for the production thereof and use of the same for controlling pathogenic fungi
12/27/2002CA2450936A1 Purine inhibitors of phosphodiesterase (pde) 7
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