Patents
Patents for C07D 463 - Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula: , e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring (613)
08/1993
08/25/1993EP0557035A2 An ester cleavage process for use with beta-lactams
08/24/1993US5239069 Amino protecting group
08/24/1993US5239068 Cephalosporins
08/19/1993CA2089544A1 Methods and compounds for the preparation of carbacephems
08/19/1993CA2089540A1 Ester cleavage process for use with .beta.-lactams
08/11/1993CN1075146A Process for making antimicrobial quinolonyl lactams
05/1993
05/12/1993EP0540609A1 Cephalosporins and homologues, preparations and pharmaceutical compositions
05/12/1993EP0540606A1 Cephalosporins and homologues, preparations and pharmaceutical compositions
04/1993
04/21/1993CN1020340C 1-carbacephalosporin antibiotics
04/15/1993WO1993007154A1 Process for making antimicrobial quinolonyl lactams
04/15/1993CA2120493A1 Process for making antimicrobial quinolonyl lactams
02/1993
02/23/1993US5189158 Acid mediated ring closure
02/03/1993EP0525057A1 Antimicrobial quinolonyl lactams
01/1993
01/20/1993EP0523585A2 Improvements in or relating to beta lactam production
01/19/1993US5180719 Antimicrobial quinolonyl lactam esters
01/12/1993US5179088 Administering bactericides
12/1992
12/08/1992US5169945 Reacting imide with secondary amine to form amide which protects amine during nucleophilic reactions
12/02/1992CN1066655A Process for preparing doubly blocked 1-carba(1-dethia)-3-cephem-4-carboxylic acids
11/1992
11/17/1992CA1310323C Process and preparing cis-1-carba(1-dethia)cephalosporins and intermediates therefor
11/11/1992EP0512813A2 Process for preparing doubly blocked 1-carba(1-dethia)-3-cephem-4-carboxylic acids
11/11/1992CA2067708A1 Process for preparing doubly blocked 1-carba(1-dethia)-3-cephem-4-carboxylic acids
10/1992
10/28/1992EP0511001A2 Ring-closure method for 1-carbacephalosporin six-membered ring
10/27/1992US5158946 Antibiotics, bactericides
10/26/1992CA2066493A1 Ring-closure method for 1-carbacephalosporin six-membered ring
10/07/1992CN1065061A 4-substituted azetidinodes as precursors to 2-substituted-2-carboxy carbapenem antibiotics and method of producing them
09/1992
09/23/1992EP0504612A2 Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them
09/23/1992EP0504216A1 Cephalosporins, processes for their preparation, intermediates and pharmaceutical compositions containing them
09/23/1992EP0222022B1 Process for producing beta-lactam derivatives
09/21/1992CA2063326A1 Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them
08/1992
08/25/1992US5142039 β-lactam antibiotics
08/05/1992CN1063284A Antibacterial agents
08/04/1992CA1305964C2 1-carba (dethia) cephalosporin 3-triflate ester antibiotics
07/1992
07/29/1992CN1063104A Trifluoromethyl 1-carba (1-dethia) cephems
07/22/1992EP0495585A1 Antibacterial agents
07/15/1992EP0494733A1 Trifluoromethyl 1-carba(1-dethia)cephems
07/11/1992CA2058699A1 Trifluoromethyl 1-carba(1-dethia)cephems
07/07/1992US5128336 3-(substituted)-1-carba(dethia)-3-cephems
07/07/1992CA1304744C Process for intermediates to 1-carbapenems and 1- carbacephems
05/1992
05/26/1992US5116972 4-(2,3 epoxypropane)azetidinones
05/19/1992US5114933 Cephalosporin compounds
05/13/1992EP0485103A2 Process for cleavage of esters during the production of cephalosporins
05/06/1992EP0484030A2 Antibiotic C-3 cyclobutenedione substituted (1-carba)cephalosporin compounds, compositions, and methods of use thereof
05/06/1992CA2054451A1 Process for cleavage of esters during the production of cephalosporins
04/1992
04/23/1992CA2053159A1 Antibiotic c-3 cyclobutenedione substituted (1-carba) cephalosporin compounds, compositions, and methods of use thereof
04/22/1992CN1060469A Process for preparing cephalosporins derivants
04/21/1992US5106968 Process for bicyclic β-lactams diazo-β-keto-butyrate-intermediates for bicyclic β-lactams
04/21/1992US5106842 Antibiotic c-3 cyclobutenedione substituted (1-carba)cephalosporin compounds, compositions, and methods of use thereof
03/1992
03/24/1992US5099015 Trifluoromethyl 1-carba(1-dethia)cephems
03/10/1992US5095107 Process for cleavage of esters during the production of cephalosporins
02/1992
02/25/1992US5091525 7beta- 2'-(R)-2'-(p-hydroxyphenyl-2'-amino-acetamido!-3-chloro -3-(1-carbadethiacephem)-4-carboxylic acid
02/18/1992US5089610 Ring-closure method for 1-carbacephalosporin six-membered ring
02/18/1992US5089490 Cephem derivatives
02/18/1992CA1295995C Antibacterial compounds, their production and use
02/06/1992WO1992001696A1 Cephalosporins and homologues, preparations and pharmaceutical compositions
02/06/1992WO1992001695A1 Cephalosporins and homologues, preparations and pharmaceutical compositions
12/1991
12/31/1991US5077287 3-thiazolylthio carbacephem antibacterial agents
12/25/1991CN1015178B Process and intermediates for beta-lactam antibiotics
12/18/1991CN1015103B Process for preparing 3-halo-1-carbo-3-cephem-4-carboxylic acid and its deriv.
12/11/1991EP0460881A1 Process for bicyclic beta-lactams
12/07/1991CA2043939A1 Process for bicyclic .beta.-lactams
12/03/1991US5070194 Deprotection of intermediates
11/1991
11/21/1991EP0457512A2 New amino protecting group
11/15/1991CA2041897A1 Amino protecting group
11/12/1991US5064649 Cephalosporin derivatives
10/1991
10/31/1991WO1991016327A1 Antimicrobial quinolonyl lactams
10/31/1991WO1991016310A1 Antimicrobial quinolone thioureas
10/31/1991CA2078444A1 Antimicrobial quinolonyl lactams
10/31/1991CA2077435A1 Novel antimicrobial quinolone thioureas
10/22/1991CA1291118C Process for preparing cephalosporin compounds
10/01/1991US5053500 Intermediates for the preparation of beta-lactam antibiotics
09/1991
09/24/1991US5051502 Rhodium catalyzed cyclization process for bicyclic β-lactams
09/17/1991US5049558 Quaternized nitrogen-heterocycle substituted
09/11/1991EP0445925A1 1-Carba(dethia)caphalosporin antibiotics
08/1991
08/07/1991CN1053611A Crystalline hydrochloride of new beta-lactam antibiotic and process therefor
08/06/1991US5037975 Cephalosporin free radical compounds
07/1991
07/31/1991EP0439353A1 Crystalline hydrochloride of new beta-lactam antibiotic and process therefor
06/1991
06/27/1991WO1991009038A1 Cephalosporins, processes for their preparation, intermediates and pharmaceutical compositions containing them
06/12/1991EP0431794A2 3-Fluorosulfonyloxyceph-3-EM displacement process
06/05/1991EP0430556A2 (1-Akylsubstituted) and 1,1-dialkylsubstituted) carbacephalosporins
05/1991
05/28/1991US5019571 1-carbacephalosporin antibiotics
05/28/1991CA2030367A1 (1-alkylsubstituted) and (1,1-dialkylsubstituted) carbacephalosporins
05/22/1991CA2147460A1 3-fluorosulfonyloxyceph-3-em displacement process
04/1991
04/16/1991CA1283096C Antibacterial compounds
03/1991
03/20/1991EP0418020A2 Cephalosporinderivatives, process for their preparation and pharmaceutical compositions
03/20/1991CN1050023A Process for preparation of cephalosporin derivative
03/13/1991EP0416814A2 Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates
03/13/1991EP0416810A2 Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates
03/05/1991CA2024396A1 Compounds
01/1991
01/08/1991US4983732 Cehmical intermediates for beta-lactam antibiotics
12/1990
12/27/1990EP0404584A2 Oxidation and reduction method to produce 4-acyloxyazetidin-2-one
12/25/1990US4980348 Carbacephem antibiotics
12/21/1990CA2019483A1 Oxidation and reduction method to produce 4-acyloxyazetidin-2-one
12/18/1990CA1277978C Antibacterial compounds, there production and use
12/11/1990US4977257 DMF solvates of a β-lactam antibiotic
12/11/1990US4976834 Asymmetric photochemical reaction process
10/1990
10/31/1990EP0395219A2 Cephalosporins and their homologues, process for their preparation and pharmaceutical compositions
10/09/1990US4962100 3-amidazolium-1-yl-methyl,7-(2-(5-amino-1,2,4-thiadiazol-3-yl) 2-alkoxyiminoacetamido) derivatives; active against cephalosporin-resistant bacteria
09/1990
09/30/1990CA2013391A1 Compounds
09/26/1990EP0389176A2 Beta-lactams and processes for their preparation
09/25/1990CA1274519A1 1-carbacephalosporin antibiotics
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